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3,3-Dimethoxypropiononitril
Artikel-Nr:
(BLEG575309)
Lieferant:
BIOLEGEND INC
Hersteller-Artikelnummer::
575309
Lokale Artikelnummer::
BLEG575309
Beschreibung:
ELISA Standard 4-Pack contains four vials of recombinant mouse IFN-gamma at >5 ng per vial. Recommended for ELISA application only. Standards are calibrated against a BioLegend Master Calibrator.
VE:
1 * 1 Pack.
 This is a MarketSource item. Additional charges may apply
Artikel-Nr:
(BOSSBS-3345R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3345R-A488
Lokale Artikelnummer::
BOSSBS-3345R-A488
Beschreibung:
Serine/threonine-protein kinase that performs several important functions throughout M phase of the cell cycle, including the regulation of centrosome maturation and spindle assembly, the removal of cohesins from chromosome arms, the inactivation of APC/C inhibitors, and the regulation of mitotic exit and cytokinesis. Required for recovery after DNA damage checkpoint and entry into mitosis. Required for kinetochore localization of BUB1B. Phosphorylates SGOL1. Required for spindle pole localization of isoform 3 of SGOL1 and plays a role in regulating its centriole cohesion function. Phosphorylates BORA, and thereby promotes the degradation of BORA. Contributes to the regulation of AURKA function. Regulates TP53 stability through phosphorylation of TOPORS. Phosphorylates NEDD1. NEDD1 phosphorylation promotes subsequent targeting of the gamma-tubulin ring complex (gTuRC) to the centrosome, an important step for spindle formation. Phosphorylates both ECT2 and RACGAP1, and thereby stimulates their interaction that is essential for the cleavage furrow formation. Promotes the central spindle recruitment of ECT2.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3345R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3345R-HRP
Lokale Artikelnummer::
BOSSBS-3345R-HRP
Beschreibung:
Serine/threonine-protein kinase that performs several important functions throughout M phase of the cell cycle, including the regulation of centrosome maturation and spindle assembly, the removal of cohesins from chromosome arms, the inactivation of APC/C inhibitors, and the regulation of mitotic exit and cytokinesis. Required for recovery after DNA damage checkpoint and entry into mitosis. Required for kinetochore localization of BUB1B. Phosphorylates SGOL1. Required for spindle pole localization of isoform 3 of SGOL1 and plays a role in regulating its centriole cohesion function. Phosphorylates BORA, and thereby promotes the degradation of BORA. Contributes to the regulation of AURKA function. Regulates TP53 stability through phosphorylation of TOPORS. Phosphorylates NEDD1. NEDD1 phosphorylation promotes subsequent targeting of the gamma-tubulin ring complex (gTuRC) to the centrosome, an important step for spindle formation. Phosphorylates both ECT2 and RACGAP1, and thereby stimulates their interaction that is essential for the cleavage furrow formation. Promotes the central spindle recruitment of ECT2.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13264R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13264R-CY7
Lokale Artikelnummer::
BOSSBS-13264R-CY7
Beschreibung:
There are two forms of glutamic acid decarboxylases (GADs) that exist in brain: GAD-65 (also known as GAD2) and GAD-67 (also known as GAD1, GAD or SCP). GAD-65 and GAD-67 are members of the group II decarboxylase family of proteins and are responsible for catalyzing the rate limiting step in the production of GABA (gamma-aminobutyric acid) from L-glutamic acid. Although both GADs are found in brain, GAD-65 localizes to synaptic vesicle membranes in nerve terminals, while GAD-67 is distributed throughout the cell. GAD-67 is responsible for the basal levels of GABA synthesis. In the case of a heightened demand for GABA in neurotransmission, GAD-65 transiently activates to assist in GABA production. As a member of the group II decarboxylase family, GADL1 (Glutamate decarboxylase-like protein 1) is a 521 amino acid protein that utilizes pyridoxal phosphate as a cofactor for its carboxylase activity. There are two isoforms of GADL1 that exist as a result of alternative splicing events.
VE:
1 * 100 µl
Artikel-Nr:
(USBI151612)
Lieferant:
US Biological
Hersteller-Artikelnummer::
151612
Lokale Artikelnummer::
USBI151612
Beschreibung:
Anti-Beta-Thromboglobulin Mouse Monoclonal Antibody
VE:
1 * 200 µG
Artikel-Nr:
(USBII7662-10L)
Lieferant:
US Biological
Hersteller-Artikelnummer::
I7662-10L
Lokale Artikelnummer::
USBII7662-10L
Beschreibung:
Anti-Interferon beta Rabbit Polyclonal Antibody
VE:
1 * 200 µl
Artikel-Nr:
(USBI029888)
Lieferant:
US Biological
Hersteller-Artikelnummer::
029888
Lokale Artikelnummer::
USBI029888
Beschreibung:
Anti-SDF-1-beta Rabbit Polyclonal Antibody
VE:
1 * 100 µG
Artikel-Nr:
(BOSSBS-13591R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13591R-A488
Lokale Artikelnummer::
BOSSBS-13591R-A488
Beschreibung:
Proteins internalized into the endocytic pathway are usually degraded. Efficient proteolysis requires denaturation, induced by acidic conditions within lysosomes, and reduction of inter- and intrachain disulfide bonds. Cytosolic reduction is mediated enzymatically by thioredoxin. In the endocytic pathway, reduction of protein disulfide bonds is important for the generation of MHC class II-peptide complexes. This process is catalyzed by a gamma-interferon-inducible thiol reductase (GILT). GILT is synthesized as a precursor, and following delivery to MHC class II-containing compartments (MIICs), is processed to the mature form via cleavage of amino- and carboxy-terminal propeptides. A lysosomal thiol reductase, GILT, is optimally active at low pH and capable of catalyzing disulfide bond reduction both in vivo and in vitro. GILT is expressed constitutively in antigen-presenting cells and is induced by g-interferon in other cell types, suggesting a potentially important role in antigen processing. Additionally, T cell recognition of select exogenous and endogenous epitopes is dependent on tumor cell expression of GILT. The absence of GILT in melanomas alters antigen processing and the hierarchy of immunodominant epitope presentation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13591R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13591R-HRP
Lokale Artikelnummer::
BOSSBS-13591R-HRP
Beschreibung:
Proteins internalized into the endocytic pathway are usually degraded. Efficient proteolysis requires denaturation, induced by acidic conditions within lysosomes, and reduction of inter- and intrachain disulfide bonds. Cytosolic reduction is mediated enzymatically by thioredoxin. In the endocytic pathway, reduction of protein disulfide bonds is important for the generation of MHC class II-peptide complexes. This process is catalyzed by a gamma-interferon-inducible thiol reductase (GILT). GILT is synthesized as a precursor, and following delivery to MHC class II-containing compartments (MIICs), is processed to the mature form via cleavage of amino- and carboxy-terminal propeptides. A lysosomal thiol reductase, GILT, is optimally active at low pH and capable of catalyzing disulfide bond reduction both in vivo and in vitro. GILT is expressed constitutively in antigen-presenting cells and is induced by g-interferon in other cell types, suggesting a potentially important role in antigen processing. Additionally, T cell recognition of select exogenous and endogenous epitopes is dependent on tumor cell expression of GILT. The absence of GILT in melanomas alters antigen processing and the hierarchy of immunodominant epitope presentation.
VE:
1 * 100 µl
Artikel-Nr:
(USBI042134-BIOTIN)
Lieferant:
US Biological
Hersteller-Artikelnummer::
042134-BIOTIN
Lokale Artikelnummer::
USBI042134-BIOTIN
Beschreibung:
Anti-SOCS7 Rabbit Polyclonal Antibody (Biotin)
VE:
1 * 200 µl
Artikel-Nr:
(ABCAAB126234-50)
Lieferant:
Abcam
Hersteller-Artikelnummer::
AB126234-50
Lokale Artikelnummer::
ABCAAB126234-50
Beschreibung:
Anti-Nicotinic Acetylcholine Receptor beta Rabbit Polyclonal Antibody
VE:
1 * 50 µl
This is a MarketSource item. Additional charges may apply
Lieferant:
Thermo Scientific
Beschreibung:
CAS No.: 305-84-0
Artikel-Nr:
(ABCAAB3581-50)
Lieferant:
Abcam
Hersteller-Artikelnummer::
AB3581-50
Lokale Artikelnummer::
ABCAAB3581-50
Beschreibung:
Anti-Glucocorticoid Receptor beta Rabbit Polyclonal Antibody
VE:
1 * 50 µl
This is a MarketSource item. Additional charges may apply
Artikel-Nr:
(USBII7662-10N)
Lieferant:
US Biological
Hersteller-Artikelnummer::
I7662-10N
Lokale Artikelnummer::
USBII7662-10N
Beschreibung:
Anti-Interferon, beta, neutralizing Rabbit Polyclonal Antibody
VE:
1 * 100 µl
Artikel-Nr:
(NOVUNB110-58783B)
Lieferant:
Novus Biologicals
Hersteller-Artikelnummer::
NB110-58783B
Lokale Artikelnummer::
NOVUNB110-58783B
Beschreibung:
Anti-Spectrin beta 3 Rabbit Polyclonal Antibody (Biotin)
VE:
1 * 0,1 mL
Artikel-Nr:
(ABCAAB3331-100)
Lieferant:
Abcam
Hersteller-Artikelnummer::
AB3331-100
Lokale Artikelnummer::
ABCAAB3331-100
Beschreibung:
Anti-Proteasome 20S beta 6 Rabbit Polyclonal Antibody
VE:
1 * 100 µG
This is a MarketSource item. Additional charges may apply
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Dieses Produkt kann nur an eine Lieferadresse versandt werden die über die entsprechende Lizenzen verfügt. Für weitere Hilfe bitte kontaktieren Sie Ihr VWR Vertriebszentrum.
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