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VARLP032522BAKR00001
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VARLP032522BAKR00001
Artikel-Nr:
(BOSSBS-5808R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5808R-HRP
Lokale Artikelnummer::
BOSSBS-5808R-HRP
Beschreibung:
CDO1 (cysteine dioxygenase, type I) is a 200 amino acid protein that belongs to the cysteine dioxygenase family and is involved in organosulfur biosynthesis. Existing as a monomer and expressed at high levels in liver and placenta and at lower levels in brain, pancreas and heart, CDO1 functions as a dioxygenase that uses iron and zinc as cofactors to catalyze the conversion of L-cysteine and oxygen to 3-sulfinoalanine. Via its catalytic activity, CDO1 is involved in pyruvate-, sulfate- and taurine-related metabolic pathways and is a crucial regulator of cysteine concentrations within the cell. Human CDO1 shares 94% amino acid identity with its rat counterpart, suggesting a conserved role between species. The gene encoding CDO1 maps to human chromosome 5, which contains 181 million base pairs and comprises nearly 6% of the human genome. Deletion of the p arm of chromosome 5 leads to Cri du chat syndrome, while deletion of the q arm or of chromosome 5 altogether is common in therapy-related acute myelogenous leukemias and myelodysplastic syndrome.PathwayOrganosulfur biosynthesis; taurine biosynthesis; hypotaurine from L-cysteine: step 1/2.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5926R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5926R-A555
Lokale Artikelnummer::
BOSSBS-5926R-A555
Beschreibung:
Belongs to the G-protein coupled receptor 1 family. Mas subfamily.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5474R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5474R-A555
Lokale Artikelnummer::
BOSSBS-5474R-A555
Beschreibung:
The classic group of MBP isoforms (isoform 4-isoform 14) are with PLP the most abundant protein components of the myelin membrane in the CNS. They have a role in both its formation and stabilization. The smaller isoforms might have an important role in remyelination of denuded axons in multiple sclerosis. The non-classic group of MBP isoforms (isoform 1-isoform 3/Golli-MBPs) may preferentially have a role in the early developing brain long before myelination, maybe as components of transcriptional complexes, and may also be involved in signaling pathways in T-cells and neural cells. Differential splicing events combined with optional post-translational modifications give a wide spectrum of isomers, with each of them potentially having a specialized function. Induces T-cell proliferation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0451R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0451R
Lokale Artikelnummer::
BOSSBS-0451R
Beschreibung:
PIPKH, also known as PIP5KL1 (phosphatidylinositol-4-phosphate 5-kinase-like 1), is a 394 amino acid phosphoinositide kinase-like protein that contains one PIPK domain. Although PIPKH lacks intrinsic lipid kinase activity, it associates with type I PIPKs and may play a role in localization of PIPK activity. Encoded by a gene that maps to human chromosome 9q34.11, PIPKH localizes to cytoplasm, specifically to large cytoplasmic vesicular structures, and exists as two alternatively spliced isoforms. Highly expressed in brain and testis, PIPKH is also expressed at very low levels in heart, spleen, lung, liver, skeletal muscle and kidney. PIPKH heterodimerizes with other type I phosphatidylinositol-4-phosphate 5-kinases, and may function as a scaffold to localize and regulate kinases to specific cell compartments. Overexpression of PIPKH may suppress cell proliferation and migration in human gastric cancer cells and may also inhibit cervical cancer formation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2406R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2406R-CY5.5
Lokale Artikelnummer::
BOSSBS-2406R-CY5.5
Beschreibung:
Plays a key role in glycolysis and gluconeogenesis. In addition, may also function as scaffolding protein (By similarity).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11127R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11127R-A488
Lokale Artikelnummer::
BOSSBS-11127R-A488
Beschreibung:
Integrin alpha-M/beta-2 is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles. It is identical with CR-3, the receptor for the iC3b fragment of the third complement component. It probably recognizes the R-G-D peptide in C3b. Integrin alpha-M/beta-2 is also a receptor for fibrinogen, factor X and ICAM1. It recognizes P1 and P2 peptides of fibrinogen gamma chain.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5940R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5940R-A350
Lokale Artikelnummer::
BOSSBS-5940R-A350
Beschreibung:
The protein encoded by this gene belongs to the DEAD-like helicase superfamily. It shares similarity with Saccharomyces cerevisiae RAD54 and RDH54, both of which are involved in homologous recombination and repair of DNA. This protein binds to double-stranded DNA, and displays ATPase activity in the presence of DNA. This gene is highly expressed in testis and spleen, which suggests active roles in meiotic and mitotic recombination. Homozygous mutations of this gene were observed in primary lymphoma and colon cancer.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9052R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9052R-A488
Lokale Artikelnummer::
BOSSBS-9052R-A488
Beschreibung:
The exosome is a multi-protein complex composed of several highly conserved subunits, some of which are 3’ to 5’ exoribonucleases. The complex is involved in a variety of cellular processes and is responsible for degrading unstable mRNAs that contain AU-rich elements (AREs) in their untranslated 3’ regions. DIS3, also known as RRP44, is a 958 amino acid protein that localizes to both the cytoplasm and the nucleus and contains one PINc domain. Widely expressed with highest expression in testis, DIS3 functions as a component of the exosome exoribonuclease complex and is required for processing of 7S pre-RNA into a mature nuclear complex and, ultimately, for proper mitotic progression. Abnormal expression levels of DIS3 may be associated with colon cancer, suggesting a role for DIS3 in tumorigenesis. Multiple isoforms of DIS3 exist due to alternative splicing events.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5903R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5903R-A555
Lokale Artikelnummer::
BOSSBS-5903R-A555
Beschreibung:
Promotes cell survival. Blocks dexamethasone-induced apoptosis. Mediates survival of postmitotic Sertoli cells by suppressing death-promoting activity of BAX.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5713R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5713R-CY5
Lokale Artikelnummer::
BOSSBS-5713R-CY5
Beschreibung:
HOXA5 upregulates both p53 promoter-reporter constructs and endogenous p53 synthesis, leading to apoptosis. HOXA5 is detectable in approximately one-third of primary tumors. Lack of HOXA5 expression strongly correlates with methylation of its promoter region, suggesting a causal role for methylation in the silencing of HOXA5 gene expression. HOXA5 expression is an important step in tumorigenesis and loss of expression of p53 in human breast cancer may be primarily due to lack of expression of HOXA5.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5833R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5833R-HRP
Lokale Artikelnummer::
BOSSBS-5833R-HRP
Beschreibung:
This gene encodes a member of the "fused gene" family of proteins, which contain N terminus EF hand domains and multiple tandem peptide repeats. The encoded protein contains two EF hand Ca2+ binding domains in its N terminus and two glutamine and threonine rich 60 amino acid repeats in its C terminus. This gene, also known as squamous epithelial heat shock protein 53, may play a role in the mucosal/epithelial immune response and epidermal differentiation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0727R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0727R-A555
Lokale Artikelnummer::
BOSSBS-0727R-A555
Beschreibung:
CXorf36
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-15146R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-15146R-CY7
Lokale Artikelnummer::
BOSSBS-15146R-CY7
Beschreibung:
C2orf15
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-15165R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-15165R-A750
Lokale Artikelnummer::
BOSSBS-15165R-A750
Beschreibung:
C3orf14 (chromosome 3 open reading frame 14), also known as HT021, is a 128 amino acid protein that is encoded by a gene mapping to human chromosome 3p14.2. Chromosome 3 is made up of approximately 214 million bases encoding over 1,100 genes. Notably, there is a chemokine receptor gene cluster and a variety of human cancer related loci on chromosome 3. Particular regions of the chromosome 3 short arm are deleted in many types of cancer cells. Key tumor suppressing genes on chromosome 3 encode apoptosis mediator RASSF1, cell migration regulator HYAL1 and angiogenesis suppressor SEMA3B. Marfan Syndrome, porphyria, von Hippel-Lindau syndrome, osteogenesis imperfecta and Charcot-Marie-Tooth disease are a few of the numerous genetic diseases associated with chromosome 3.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3989R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3989R-CY5.5
Lokale Artikelnummer::
BOSSBS-3989R-CY5.5
Beschreibung:
Glycogen synthase catalyzes the rate-limiting step in glycogen synthesis. Its activity is regulated by a complex phosphorylation-dephosphorylation mechanism and by allosteric stimulators and inhibitors. Two isozymes of synthase, a skeletal muscle type (Glycogen synthase 1 - GYS1) and a liver type (Glycogen synthase 2 - GYS2), have been identified.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4593R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4593R-HRP
Lokale Artikelnummer::
BOSSBS-4593R-HRP
Beschreibung:
May play an essential role in local proteolysis of the extracellular matrix and in leukocyte migration. Could play a role in bone osteoclastic resorption. Cleaves KiSS1 at a Gly-|-Leu bond. Cleaves type IV and type V collagen into large C-terminal three quarter fragments and shorter N-terminal one quarter fragments. Degrades fibronectin but not laminin or Pz-peptide.
VE:
1 * 100 µl
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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