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trans-1,4-Cyclohexanedimethanol
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trans-1,4-Cyclohexanedimethanol
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
1'-(tert-Butoxycarbonyl)-1,4'-bipiperidine-4-carboxylic acid 97%
Artikel-Nr:
(APOSPC3518-1G)
Lieferant:
APOLLO SCIENTIFIC
Hersteller-Artikelnummer::
PC3518-1G
Lokale Artikelnummer::
APOSPC3518-1G
Beschreibung:
8-(2-Fluoro-4-nitrophenyl)-1,4-dioxa-8-azaspiro[4.5]decane
VE:
1 * 1 g
Artikel-Nr:
(APOSOR110370-1G)
Lieferant:
APOLLO SCIENTIFIC
Hersteller-Artikelnummer::
OR110370-1G
Lokale Artikelnummer::
APOSOR110370-1G
Beschreibung:
2-Methyl-3-oxo-3,4-dihydro-2H-1,4-benzoxazine-8-carboxylic acid
VE:
1 * 1 g
Artikel-Nr:
(APOSOR111537-1G)
Lieferant:
APOLLO SCIENTIFIC
Hersteller-Artikelnummer::
OR111537-1G
Lokale Artikelnummer::
APOSOR111537-1G
Beschreibung:
2-Methyl-3,4-dihydro-2H-pyrido[3,2-b][1,4]oxazine
VE:
1 * 1 g
Artikel-Nr:
(BOSSBS-8333R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8333R-A488
Lokale Artikelnummer::
BOSSBS-8333R-A488
Beschreibung:
RDH13, also known as all-trans and 9-cis retinol dehydrogenase 13 or SDR7C3, is a 331 amino acid mitochondrial protein belonging to the short-chain dehydrogenases/reductases (SDR) family. Widely expressed, mostly in eye, pancreas, placenta and lung, RDH13 localizes on the outer side of the inner mitochondrial membrane. Related to microsomal retinoid oxidoreductase RDH11, RDH13 is considered to be a major enzyme among the RDH family of proteins. Catalytically active, RDH13 recognizes retinoids as substrates and may function in retinoic acid production. RDH13 may function to protect the mitochondria against oxidative stress. Leber congenital amaurosis (LCA) type 3, an inherited autosomal recessive retinal disease, has been associated with defects of RDH13. LCA represents the most common genetic cause of congenital visual impairment in infants and children.
VE:
1 * 100 µl
Artikel-Nr:
(APOSOR13149-1G)
Lieferant:
APOLLO SCIENTIFIC
Hersteller-Artikelnummer::
OR13149-1G
Lokale Artikelnummer::
APOSOR13149-1G
Beschreibung:
2-Chloro-N-(2,3-dihydro-1,4-benzodioxin-6-yl)acetamide
VE:
1 * 1 g
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
7-Fluoro-2H-benzo[b][1,4]oxazin-3(4H)-one
Artikel-Nr:
(APOSOR46043-5G)
Lieferant:
APOLLO SCIENTIFIC
Hersteller-Artikelnummer::
OR46043-5G
Lokale Artikelnummer::
APOSOR46043-5G
Beschreibung:
7-Bromo-2H-benzo[b][1,4]oxazin-3(4H)-one
VE:
1 * 5 g
Artikel-Nr:
(BOSSBS-8333R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8333R-A555
Lokale Artikelnummer::
BOSSBS-8333R-A555
Beschreibung:
RDH13, also known as all-trans and 9-cis retinol dehydrogenase 13 or SDR7C3, is a 331 amino acid mitochondrial protein belonging to the short-chain dehydrogenases/reductases (SDR) family. Widely expressed, mostly in eye, pancreas, placenta and lung, RDH13 localizes on the outer side of the inner mitochondrial membrane. Related to microsomal retinoid oxidoreductase RDH11, RDH13 is considered to be a major enzyme among the RDH family of proteins. Catalytically active, RDH13 recognizes retinoids as substrates and may function in retinoic acid production. RDH13 may function to protect the mitochondria against oxidative stress. Leber congenital amaurosis (LCA) type 3, an inherited autosomal recessive retinal disease, has been associated with defects of RDH13. LCA represents the most common genetic cause of congenital visual impairment in infants and children.
VE:
1 * 100 µl
Artikel-Nr:
(APOSOR110432-1G)
Lieferant:
APOLLO SCIENTIFIC
Hersteller-Artikelnummer::
OR110432-1G
Lokale Artikelnummer::
APOSOR110432-1G
Beschreibung:
N-(2-Chloroethyl)-2,3-dihydro-4H-1,4-benzoxazine-4-carboxamide
VE:
1 * 1 g
Artikel-Nr:
(APOSOR33631-1G)
Lieferant:
APOLLO SCIENTIFIC
Hersteller-Artikelnummer::
OR33631-1G
Lokale Artikelnummer::
APOSOR33631-1G
Beschreibung:
3,4-Dihydro-2H-1,4-benzoxazin-6-ylmethanol 95%
VE:
1 * 1 g
Artikel-Nr:
(BOSSBS-1228R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1228R-CY7
Lokale Artikelnummer::
BOSSBS-1228R-CY7
Beschreibung:
Clathrin-mediated endocytosis is the pathway by which many receptors for nutrients and hormones are internalized to be recycled or down-regulated. During formation of clathrin coated membranes, clathrin co-assembles with heterotetrameric molecules known as assembly polypeptides (APs) or adaptors which form a layer of protein coat between the clathrin lattice and the membrane. There are two characterized adaptors AP1 and AP2. AP1 is associated with clathrin coated vesicles at the trans-Golgi network and AP2 is associated with the endocytic clathrin coated vesicles at the plasma membrane and has been shown to specifically interact with Shc and EGF receptor. AP2 is composed of four subunits, two separate 100 kDa gene products with similar domain structures (alpha and beta adaptin) and a 50 and 17 kDa subunit. There are two alpha-adaptin genes, alpha A and alpha C which have a tissue specific pattern of expression.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9156R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9156R-A647
Lokale Artikelnummer::
BOSSBS-9156R-A647
Beschreibung:
SH3MD2 acts as a scaffold protein, contributes to Rac-induced signal transduction such as JNKs (MAPK8 and MAPK9) activation and induces apoptosis. Within a signaling complex, it probably recruits protein kinases such as MAP3K10 or MAP3K11 which are in turn activated leading to the sequential activation of MAP2K4, MAP2K7 and JNKs (MAPK8 and MAPK9). SH3MD2 may be involved in targeting of HIV-1 GAG and GAG-POL polyproteins to the plasma membrane. This gene encodes a protein containing an N-terminus RING-finger, four SH3 domains, and a region implicated in binding of the Rho GTPase Rac. Via the RING-finger, the encoded protein has been shown to function as an ubiquitin-protein ligase involved in protein sorting at the trans-Golgi network. The encoded protein may also act as a scaffold for the c-Jun N-terminal kinase signaling pathway, facilitating the formation of a functional signaling module. There are two named isoforms.
VE:
1 * 100 µl
Lieferant:
Alfa Aesar
Beschreibung:
2,3,4,5-Tetrahydro-1H-benzo[e][1,4]diazepine 95%
Artikel-Nr:
(BOSSBS-1228R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1228R-CY5
Lokale Artikelnummer::
BOSSBS-1228R-CY5
Beschreibung:
Clathrin-mediated endocytosis is the pathway by which many receptors for nutrients and hormones are internalized to be recycled or down-regulated. During formation of clathrin coated membranes, clathrin co-assembles with heterotetrameric molecules known as assembly polypeptides (APs) or adaptors which form a layer of protein coat between the clathrin lattice and the membrane. There are two characterized adaptors AP1 and AP2. AP1 is associated with clathrin coated vesicles at the trans-Golgi network and AP2 is associated with the endocytic clathrin coated vesicles at the plasma membrane and has been shown to specifically interact with Shc and EGF receptor. AP2 is composed of four subunits, two separate 100 kDa gene products with similar domain structures (alpha and beta adaptin) and a 50 and 17 kDa subunit. There are two alpha-adaptin genes, alpha A and alpha C which have a tissue specific pattern of expression.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5814R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5814R-A488
Lokale Artikelnummer::
BOSSBS-5814R-A488
Beschreibung:
Prominin 2 is a 112 kDa glycoporotein structurally related to Prominin 1 (CD133) although amino acid similarity is not more than 30%, but their genomic organization is strikingly similar. Like Prominin 1, the prominin 2 exhibit similar membrane topology with 5 trans-membrane domains and two large glycosylated extracellular domains. Similar to Prominin1 localization, the Prominin 2 is also associated with membrane protrusions of the epithelial cells from adult kidney, and all along the digestive track and other epithelial tissues.Prominin 2 expression is down-regulated in aggressive prostate cancer cell lines and transient transfection of PROML2 expression vectors has been shown to induce apoptosis in cultured prostate cancer cells, suggesting a tumor suppressive role for Prominin 2. Prominin 2 expression is likely to be involved in growth suppression in the prostate, and down-regulation of Prominin 2 may disrupt normal prostatic homeostasis and lead to uncontrolled prostatic growth.
VE:
1 * 100 µl
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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