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Artikel-Nr: (BOSSBS-6117R-A350)
Lieferant: Bioss
Hersteller-Artikelnummer:: BS-6117R-A350
Lokale Artikelnummer:: BOSSBS-6117R-A350
Beschreibung: May inhibit NODAL and BMP signaling during neural patterning (By similarity). May be a tumor suppressor in brain cancers.
VE: 1 * 100 µl


Artikel-Nr: (BOSSBS-0699R-CY5.5)
Lieferant: Bioss
Hersteller-Artikelnummer:: BS-0699R-CY5.5
Lokale Artikelnummer:: BOSSBS-0699R-CY5.5
Beschreibung: Probable acetyl-CoA transporter necessary for O-acetylation of gangliosides (PubMed:9096318). Negatively regulates BMP signaling (PubMed:25402622).
VE: 1 * 100 µl


Artikel-Nr: (BOSSBS-0699R-CY7)
Lieferant: Bioss
Hersteller-Artikelnummer:: BS-0699R-CY7
Lokale Artikelnummer:: BOSSBS-0699R-CY7
Beschreibung: Probable acetyl-CoA transporter necessary for O-acetylation of gangliosides (PubMed:9096318). Negatively regulates BMP signaling (PubMed:25402622).
VE: 1 * 100 µl


Artikel-Nr: (BOSSBS-1374R-HRP)
Lieferant: Bioss
Hersteller-Artikelnummer:: BS-1374R-HRP
Lokale Artikelnummer:: BOSSBS-1374R-HRP
Beschreibung: BMPs (bone morphogenetic proteins) belong to the TGF beta superfamily of structurally related signaling proteins. Members of this superfamily are widely represented throughout the animal kingdom and have been implicated in a variety of developmental processes. Proteins of the TGF beta superfamily are disulfide-linked dimers composed of two 12-15 kDa polypeptide chains. As implied by their name, BMPs initiate, promote and regulate bone development, growth, remodelling and repair. Smad1 translocation to the nucleus is observed after the addition of BMP4 (also designated BMP2B), suggesting that BMP4 may play a role in activation of the Smad pathway. BMP is secreted into the extracellular matrix.
VE: 1 * 100 µl


Lieferant: Bertin Instruments
Beschreibung: Tragbarer Luftkeimsammler mit innovativer Trockenzyklontechnologie.

Artikel-Nr: (BOSSBS-12418R-HRP)
Lieferant: Bioss
Hersteller-Artikelnummer:: BS-12418R-HRP
Lokale Artikelnummer:: BOSSBS-12418R-HRP
Beschreibung: BAMBI is a membrane spanning glycoprotein that acts as a negative regulator of TGF-beta signaling during development. The BAMBI family of proteins are related to type I TGF-beta receptor family, however, BAMBI is a pseudoreceptor that lacks an intracellular serine/threonine kinase domain. BAMBI transcription regulation is under the influence of beta-catenin, BMP, smad3 and smad4. BAMBI expression can increase in colorectal and hepatocellular carcinomas relative to non-cancerous tissues. BAMBI is expressed at high levels during odontogenesis. BAMBI is coexpressed with Bmp-4 during early Xenopus embryogenesis and can be detected in poorly metastatic human melanoma cell lines.
VE: 1 * 100 µl


Artikel-Nr: (BOSSBS-3860R-A647)
Lieferant: Bioss
Hersteller-Artikelnummer:: BS-3860R-A647
Lokale Artikelnummer:: BOSSBS-3860R-A647
Beschreibung: CHRDL2 is a novel chordin like protein that can act as a BMP antagonist. Amember of the chordin family of proteins, it contains a signal peptide andthree CR (cysteine-rich repeat) domains. When expressed as a recombinantprotein it is secreted and binds to activin A, but not to BMP-2, -4, -6. Differential expression has been detected in developing chondrocytes, myoblasts, osteoblasts, and osteoarthritic joints. Complex alternative splicing of CHRDL2 potentially results in distinct isoforms that differ at their C termini, in the expression of signal peptide, and in the content of CR domains. CHRDL2 was originally characterized as a novel protein exclusively expressed in breast, lung, and colon tumors.
VE: 1 * 100 µl


Artikel-Nr: (BOSSBS-3860R-CY7)
Lieferant: Bioss
Hersteller-Artikelnummer:: BS-3860R-CY7
Lokale Artikelnummer:: BOSSBS-3860R-CY7
Beschreibung: CHRDL2 is a novel chordin like protein that can act as a BMP antagonist. Amember of the chordin family of proteins, it contains a signal peptide andthree CR (cysteine-rich repeat) domains. When expressed as a recombinantprotein it is secreted and binds to activin A, but not to BMP-2, -4, -6. Differential expression has been detected in developing chondrocytes, myoblasts, osteoblasts, and osteoarthritic joints. Complex alternative splicing of CHRDL2 potentially results in distinct isoforms that differ at their C termini, in the expression of signal peptide, and in the content of CR domains. CHRDL2 was originally characterized as a novel protein exclusively expressed in breast, lung, and colon tumors.
VE: 1 * 100 µl


Artikel-Nr: (BOSSBS-12418R-A680)
Lieferant: Bioss
Hersteller-Artikelnummer:: BS-12418R-A680
Lokale Artikelnummer:: BOSSBS-12418R-A680
Beschreibung: BAMBI is a membrane spanning glycoprotein that acts as a negative regulator of TGF-beta Signalling during development. The BAMBI family of proteins are related to type I TGF-beta receptor family, however, BAMBI is a pseudoreceptor that lacks an intracellular serine/threonine kinase domain. BAMBI transcription regulation is under the influence of beta-catenin, BMP, smad3 and smad4. BAMBI expression can increase in colorectal and hepatocellular carcinomas relative to non-cancerous tissues. BAMBI is expressed at high levels during odontogenesis. BAMBI is coexpressed with Bmp-4 during early Xenopus embryogenesis and can be detected in poorly metastatic human melanoma cell lines.
VE: 1 * 100 µl


Artikel-Nr: (BOSSBS-10380R-A488)
Lieferant: Bioss
Hersteller-Artikelnummer:: BS-10380R-A488
Lokale Artikelnummer:: BOSSBS-10380R-A488
Beschreibung: The protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein mediates the signals of the bone morphogenetic proteins (BMPs), which are involved in a range of biological activities including cell growth, apoptosis, morphogenesis, development and immune responses. In response to BMP ligands, this protein can be phosphorylated and activated by the BMP receptor kinase. The phosphorylated form of this protein forms a complex with SMAD4, which is important for its function in the transcription regulation. This protein is a target for SMAD-specific E3 ubiquitin ligases, such as SMURF1 and SMURF2, and undergoes ubiquitination and proteasome-mediated degradation. Alternatively spliced transcript variants encoding the same protein have been observed. [provided by RefSeq].
VE: 1 * 100 µl


Artikel-Nr: (BOSSBS-10381R-HRP)
Lieferant: Bioss
Hersteller-Artikelnummer:: BS-10381R-HRP
Lokale Artikelnummer:: BOSSBS-10381R-HRP
Beschreibung: The protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein mediates the signals of the bone morphogenetic proteins (BMPs), which are involved in a range of biological activities including cell growth, apoptosis, morphogenesis, development and immune responses. In response to BMP ligands, this protein can be phosphorylated and activated by the BMP receptor kinase. The phosphorylated form of this protein forms a complex with SMAD4, which is important for its function in the transcription regulation. This protein is a target for SMAD-specific E3 ubiquitin ligases, such as SMURF1 and SMURF2, and undergoes ubiquitination and proteasome-mediated degradation. Alternatively spliced transcript variants encoding the same protein have been observed. [provided by RefSeq].
VE: 1 * 100 µl


Artikel-Nr: (BOSSBS-3418R-CY7)
Lieferant: Bioss
Hersteller-Artikelnummer:: BS-3418R-CY7
Lokale Artikelnummer:: BOSSBS-3418R-CY7
Beschreibung: The protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein mediates the signals of the bone morphogenetic proteins (BMPs), which are involved in a range of biological activities including cell growth, apoptosis, morphogenesis, development and immune responses. In response to BMP ligands, this protein can be phosphorylated and activated by the BMP receptor kinase. The phosphorylated form of this protein forms a complex with SMAD4, which is important for its function in the transcription regulation. This protein is a target for SMAD-specific E3 ubiquitin ligases, such as SMURF1 and SMURF2, and undergoes ubiquitination and proteasome-mediated degradation. Alternatively spliced transcript variants encoding the same protein have been observed. [provided by RefSeq].
VE: 1 * 100 µl


Artikel-Nr: (BOSSBS-10380R-A647)
Lieferant: Bioss
Hersteller-Artikelnummer:: BS-10380R-A647
Lokale Artikelnummer:: BOSSBS-10380R-A647
Beschreibung: The protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein mediates the signals of the bone morphogenetic proteins (BMPs), which are involved in a range of biological activities including cell growth, apoptosis, morphogenesis, development and immune responses. In response to BMP ligands, this protein can be phosphorylated and activated by the BMP receptor kinase. The phosphorylated form of this protein forms a complex with SMAD4, which is important for its function in the transcription regulation. This protein is a target for SMAD-specific E3 ubiquitin ligases, such as SMURF1 and SMURF2, and undergoes ubiquitination and proteasome-mediated degradation. Alternatively spliced transcript variants encoding the same protein have been observed. [provided by RefSeq].
VE: 1 * 100 µl


Artikel-Nr: (BOSSBS-3418R-A350)
Lieferant: Bioss
Hersteller-Artikelnummer:: BS-3418R-A350
Lokale Artikelnummer:: BOSSBS-3418R-A350
Beschreibung: The protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein mediates the signals of the bone morphogenetic proteins (BMPs), which are involved in a range of biological activities including cell growth, apoptosis, morphogenesis, development and immune responses. In response to BMP ligands, this protein can be phosphorylated and activated by the BMP receptor kinase. The phosphorylated form of this protein forms a complex with SMAD4, which is important for its function in the transcription regulation. This protein is a target for SMAD-specific E3 ubiquitin ligases, such as SMURF1 and SMURF2, and undergoes ubiquitination and proteasome-mediated degradation. Alternatively spliced transcript variants encoding the same protein have been observed. [provided by RefSeq].
VE: 1 * 100 µl


Artikel-Nr: (BOSSBS-0699R-CY3)
Lieferant: Bioss
Hersteller-Artikelnummer:: BS-0699R-CY3
Lokale Artikelnummer:: BOSSBS-0699R-CY3
Beschreibung: Probable acetyl-CoA transporter necessary for O-acetylation of gangliosides (PubMed:9096318). Negatively regulates BMP signaling (PubMed:25402622).
VE: 1 * 100 µl


Artikel-Nr: (BOSSBS-0699R-A750)
Lieferant: Bioss
Hersteller-Artikelnummer:: BS-0699R-A750
Lokale Artikelnummer:: BOSSBS-0699R-A750
Beschreibung: Probable acetyl-CoA transporter necessary for O-acetylation of gangliosides (PubMed:9096318). Negatively regulates BMP signaling (PubMed:25402622).
VE: 1 * 100 µl


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Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das call noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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