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(S)-1-(2-Fluoro-4-methoxyphenyl)ethylamine+hydrochloride
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(S)-1-(2-Fluoro-4-methoxyphenyl)ethylamine+hydrochloride
Artikel-Nr:
(BOSSBS-15555R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-15555R-CY5
Lokale Artikelnummer::
BOSSBS-15555R-CY5
Beschreibung:
Centromere protein C 1 is a centromere autoantigen and a component of the inner kinetochore plate. The protein is required for maintaining proper kinetochore sise and a timely transition to anaphase. A putative pseudogene exists on chromosome 12.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8482R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8482R-A680
Lokale Artikelnummer::
BOSSBS-8482R-A680
Beschreibung:
Plays a major role in tight junction-specific obliteration of the intercellular space.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7013R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7013R-A680
Lokale Artikelnummer::
BOSSBS-7013R-A680
Beschreibung:
The product of this gene belongs to the family of highly homologous synovial sarcoma X (SSX) breakpoint proteins. These proteins may function as transcriptional repressors. They are also capable of eliciting spontaneously humoral and cellular immune responses in cancer patients, and are potentially useful targets in cancer vaccine-based immunotherapy. SSX1, SSX2 and SSX4 genes have been involved in the t(X;18) translocation characteristically found in all synovial sarcomas. This gene appears not to be involved in this type of chromosome translocation. Two transcript variants encoding distinct isoforms have been identified for this gene.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12471R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12471R-A750
Lokale Artikelnummer::
BOSSBS-12471R-A750
Beschreibung:
The androgen receptor gene is more than 90 kb long and codes for a protein that has 3 major functional domains: the N-terminal domain, DNA-binding domain, and androgen-binding domain. The protein functions as a steroid-hormone activated transcription factor. Upon binding the hormone ligand, the receptor dissociates from accessory proteins, translocates into the nucleus, dimerises, and then stimulates transcription of androgen responsive genes. This gene contains 2 polymorphic trinucleotide repeat segments that encode polyglutamine and polyglycine tracts in the N-terminal transactivation domain of its protein. Expansion of the polyglutamine tract causes spinal bulbar muscular atrophy (Kennedy disease). Mutations in this gene are also associated with complete androgen insensitivity (CAIS). Two alternatively spliced variants encoding distinct isoforms have been described.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6981R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6981R-A750
Lokale Artikelnummer::
BOSSBS-6981R-A750
Beschreibung:
Mediates the exchange of chloride ions against protons. Functions as antiporter and contributes to the acidification of the endosome and synaptic vesicle lumen, and may thereby affect vesicle trafficking and exocytosis. May play an important role in neuronal cell function through regulation of membrane excitability by protein kinase C. It could help neuronal cells to establish short-term memory.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6921R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6921R-A750
Lokale Artikelnummer::
BOSSBS-6921R-A750
Beschreibung:
Involved in DNA damage response and double-strand break (DSB) repair. Component of the BRCA1-A complex, acting as a central scaffold protein that assembles the various components of the complex and mediates the recruitment of BRCA1. The BRCA1-A complex specifically recognises 'Lys-63'-linked ubiquitinated histones H2A and H2AX at DNA lesion sites, leading to target the BRCA1-BARD1 heterodimer to sites of DNA damage at DSBs. This complex also possesses deubiquitinase activity that specifically removes 'Lys-63'-linked ubiquitin on histones H2A and H2AX.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1608R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1608R-FITC
Lokale Artikelnummer::
BOSSBS-1608R-FITC
Beschreibung:
Inhibits translation initiation and cap-dependent translation. May excert its function by hindering the interaction between EIF4A1 and EIF4G. Inhibits the helicase activity of EIF4A. Modulates the activation of JUN kinase. Down-regulates the expression of MAP4K1, thus inhibiting events important in driving invasion, namely, MAPK85 activation and consequent JUN-dependent transcription. May play a role in apoptosis. Tumor suppressor. Inhibits tumor promoter-induced neoplastic transformation. Binds RNA (By similarity).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1546R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1546R-CY5.5
Lokale Artikelnummer::
BOSSBS-1546R-CY5.5
Beschreibung:
Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limbs and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC. AP2 beta appears to be required for normal face and limb development and for proper terminal differentiation and function of renal tubular epithelia.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2007R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2007R-A680
Lokale Artikelnummer::
BOSSBS-2007R-A680
Beschreibung:
Auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand. Induces a robust stimulatory effect on the 3'-5' exonuclease and 3'-phosphodiesterase, but not apurinic-apyrimidinic (AP) endonuclease, APEX2 activities. Has to be loaded onto DNA in order to be able to stimulate APEX2. Plays a key role in DNA damage response (DDR) by being conveniently positioned at the replication fork to coordinate DNA replication with DNA repair and DNA damage tolerance pathways. Acts as a loading platform to recruit DDR proteins that allow completion of DNA replication after DNA damage and promote postreplication repair: Monoubiquitinated PCNA leads to recruitment of translesion (TLS) polymerases, while 'Lys-63'-linked polyubiquitination of PCNA is involved in error-free pathway and employs recombination mechanisms to synthesise across the lesion.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-10178R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-10178R-CY7
Lokale Artikelnummer::
BOSSBS-10178R-CY7
Beschreibung:
The protein encoded by this gene is an enzyme that synthesizes the prenyl side-chain of coenzyme Q, or ubiquinone, one of the key elements in the respiratory chain. The gene product catalyzes the formation of all trans-polyprenyl pyrophosphates from isopentyl diphosphate in the assembly of polyisoprenoid side chains, the first step in coenzyme Q biosynthesis. Defects in this gene are a cause of coenzyme Q10 deficiency.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3054R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3054R-CY7
Lokale Artikelnummer::
BOSSBS-3054R-CY7
Beschreibung:
Functions as a central linker protein, downstream of the B-cell receptor (BCR), bridging the SYK kinase to a multitude of signaling pathways and regulating biological outcomes of B-cell function and development. Plays a role in the activation of ERK/EPHB2, MAP kinase p38 and JNK. Modulates AP1 activation. Important for the activation of NF-kappa-B and NFAT. Plays an important role in BCR-mediated PLCG1 and PLCG2 activation and Ca(2+) mobilization and is required for trafficking of the BCR to late endosomes. However, does not seem to be required for pre-BCR-mediated activation of MAP kinase and phosphatidyl-inositol 3 (PI3) kinase signaling. May be required for the RAC1-JNK pathway. Plays a critical role in orchestrating the pro-B cell to pre-B cell transition. May play an important role in BCR-induced B-cell apoptosis.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8020R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8020R
Lokale Artikelnummer::
BOSSBS-8020R
Beschreibung:
This gene belongs to the chemokine like factor gene superfamily, a novel family that is similar to the chemokine and the transmembrane 4 superfamilies of signaling molecules. The protein encoded by this gene may play an important role in testicular development. Alternatively spliced transcript variants encoding different isoforms have been identified.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8233R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8233R-CY5.5
Lokale Artikelnummer::
BOSSBS-8233R-CY5.5
Beschreibung:
FRMPD1 has been identified as a regulatory binding partner of activator of G-protein signaling 3 (AGS3).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1981R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1981R-CY7
Lokale Artikelnummer::
BOSSBS-1981R-CY7
Beschreibung:
Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity. Required for the entry in S phase and for cell division.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7951R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7951R-CY7
Lokale Artikelnummer::
BOSSBS-7951R-CY7
Beschreibung:
The function of ADCK1 is not yet clear. It is not known if it has protein kinase activity and what type of substrate it would phosphorylate (Ser, Thr or Tyr).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7984R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7984R-CY5.5
Lokale Artikelnummer::
BOSSBS-7984R-CY5.5
Beschreibung:
Carbonic anhydrases are a large family of zincmetalloenzymes that catalyze the reversible hydration of carbondioxide. They participate in a variety of biological processes,including respiration, calcification, acid-base balance, boneresorption, and the formation of aqueous humor, cerebrospinalfluid, saliva, and gastric acid. They show extensive diversity intissue distribution and in their subcellular localization. Thecytosolic protein encoded by this gene is predominantly expressedin the salivary glands. Alternative splicing in the coding regionresults in multiple transcript variants encoding differentisoforms. [provided by RefSeq, Jul 2008].
VE:
1 * 100 µl
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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