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2-Iodobenzenesulphonic+acid
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2-Iodobenzenesulphonic+acid
Artikel-Nr:
(BOSSBS-1928R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1928R-A555
Lokale Artikelnummer::
BOSSBS-1928R-A555
Beschreibung:
Acts in vitro to stimulate the secretion of adrenocorticotropic hormone (ACTH). Binds with high affinity to CRF Receptor types 1, 2 alpha, and 2 beta.A powerful cytoprotective effect of urocortin peptide administration against ischemia and reperfusion injury has been demonstrated in isolated cardiomyocyte models, as well as in the intact heart both in vitro and in vivo.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1761R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1761R-A488
Lokale Artikelnummer::
BOSSBS-1761R-A488
Beschreibung:
The MDC gene is one of several Cys-Cys (CC) cytokine genes which are clustered on the q arm of chromosome 16. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by MDC displays chemotactic activity for natural killer cells, chronically activated T lymphocytes, monocytes and dendritic cells. It has no chemoattractant activity for eosinophils, neutrophils and resting T lymphocytes and also displays a mild activity for primary activated T lymphocytes. The product of this gene binds to chemokine receptor CCR4. This chemokine may play a role in the trafficking of activated T lymphocytes to inflammatory sites and other aspects of activated T lymphocyte physiology.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1684R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1684R-HRP
Lokale Artikelnummer::
BOSSBS-1684R-HRP
Beschreibung:
SKI is a nuclear protein that forms homodimers and heterodimers and binds to DNA to function as transcriptional activators and repressors. The SKI oncoprotein dramatically affects cell growth, differentiation, and/or survival. SKI was shown to act in distinct signaling pathways including those involving nuclear receptors, transforming growth factor beta, and tumor suppressors. SKI inhibits transforming growth factor-beta (TGF-beta) signaling through interaction with Smad proteins. SKI represses Smad-mediated transcriptional activation, probably through its action as a transcriptional co-repressor. SKI also inhibits TGF-beta-induced downregulation of genes such as c-myc.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1874R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1874R-CY5
Lokale Artikelnummer::
BOSSBS-1874R-CY5
Beschreibung:
Involved in redox regulation of the cell. Protects radical-sensitive enzymes from oxidative damage by a radical-generating system. Acts synergistically with MAP3K13 to regulate the activation of NF-kappa-B in the cytosol.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11755R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11755R-FITC
Lokale Artikelnummer::
BOSSBS-11755R-FITC
Beschreibung:
Required for pre-mRNA splicing. Can also modulate alternative splicing in vitro. Represses the splicing of MAPT/Tau exon 10. May function as export adapter involved in mRNA nuclear export such as of histone H2A. Binds mRNA which is thought to be transferred to the NXF1-NXT1 heterodimer for export (TAP/NXF1 pathway); enhances NXF1-NXT1 RNA-binding activity. RNA-binding is semi-sequence specific.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11403R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11403R-A555
Lokale Artikelnummer::
BOSSBS-11403R-A555
Beschreibung:
Gonadotropin-releasing hormone (GnRH) is released in a pulsatile manner that varies with the reproductive cycle. This hypothalamic hormone is transported to the pituitary, where it binds to specific receptors and regulates the synthesis and release of luteinizing hormone (LH) and follicle-stimulating hormone (FSH). Localized to the cell membrane, GnRHR2 mediates its own receptor activity via association with G proteins, thereby activating a phosphatidylinositol-calcium second messenger system that regulates GnRHR2 function. GnRHR2 is thought to have potent antiproliferative effects on ovarian and endometrial cancer cells, suggesting a possible role in tumor suppression. Due to alternative splicing events, GnRHR2 is expressed as two isoforms.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11636R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11636R-CY3
Lokale Artikelnummer::
BOSSBS-11636R-CY3
Beschreibung:
Contactins mediate cell surface interactions during nervous system development. Participates in oligodendrocytes generation by acting as a ligand of NOTCH1. Its association with NOTCH1 promotes NOTCH1 activation through the released notch intracellular domain (NICD) and subsequent translocation to the nucleus. Involved in motor coordination. Tissue specificity: Expressed in nervous system. Highly expressed in cerebellum. Expressed at intermediate level in thalamus, subthalamic nucleus. Weakly expressed in corpus callosum, caudate nucleus and spinal cord. Similarity: Belongs to the immunoglobulin superfamily. Contactin family. Contains 4 fibronectin type-III domains. Contains 6 Ig-like C2-type (immunoglobulin-like) domains.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9177R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9177R-A647
Lokale Artikelnummer::
BOSSBS-9177R-A647
Beschreibung:
E3 ubiquitin-protein ligase. Acts as a negative coregulator for LIM homeodomain transcription factors by mediating the ubiquitination and subsequent degradation of LIM cofactors LDB1 and LDB2 and by mediating the recruitment the SIN3a/histone deacetylase corepressor complex. Ubiquitination and degradation of LIM cofactors LDB1 and LDB2 allows DNA-bound LIM homeodomain transcription factors to interact with other protein partners such as RLIM. Plays a role in telomere length-mediated growth suppression by mediating the ubiquitination and degradation of TERF1. By targeting ZFP42 for degradation, acts as an activator of random inactivation of X chromosome in the embryo, a stochastic process in which one X chromosome is inactivated to minimize sex-related dosage differences of X-encoded genes in somatic cells of female placental mammals.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9621R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9621R-CY5
Lokale Artikelnummer::
BOSSBS-9621R-CY5
Beschreibung:
C15orf62
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0187R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0187R
Lokale Artikelnummer::
BOSSBS-0187R
Beschreibung:
Anti-IRS4 Rabbit Polyclonal Antibody
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0518R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0518R-CY5.5
Lokale Artikelnummer::
BOSSBS-0518R-CY5.5
Beschreibung:
Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA-3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA-3'). In the nucleus, contributes to global transcription and the DNA damage response, in addition to specific transcriptional activities that are related to cell development, proliferation and death. In the cytoplasm, interacts with and perturbs HK1- and VDAC1-containing complexes at the mitochondrial outer membrane, thereby impairing mitochondrial membrane potential, inducing mitochondrial leakage and promoting cell death. The phosphorylated form (mediated by ATM) plays a role in the DNA damage response and is involved in the ionizing radiation (IR)-induced S phase checkpoint control and in the recruitment of the MRN complex into the IR-induced foci (IRIF). Exhibits histone acetyltransferase (HAT) activity which specifically acetylates histones H2B and H4 in vitro. In concert with CUL3 and RBX1, promotes the degradation of KAT5 thereby attenuating its ability to acetylate and activate ATM. Can elicit oncogenic or tumor suppressor activities depending on the tissue or cell type.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1126R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1126R-CY7
Lokale Artikelnummer::
BOSSBS-1126R-CY7
Beschreibung:
Serotonin (pronounced) (5-hydroxytryptamine, or 5-HT) is a monoamine neurotransmitter synthesized in serotonergic neurons in the central nervous system (CNS) and enterochromaffin cells in the gastrointestinal tract of animals including humans. Serotonin is also found in many mushrooms and plants, including fruits and vegetables.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11334R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11334R-A488
Lokale Artikelnummer::
BOSSBS-11334R-A488
Beschreibung:
The Beta-Amyloid precursor protein (Beta-APP) is a major constituent of the amyloid deposits in patients with Alzheimer’s disease. The Beta-Amyloid precursor is known to interact with several proteins, including X11 and the G heterotrimetric protein APP-BP1. The neuronal, transmembrane protein X11 is known to bind to the ∫-Amyloid precursor protein via a phosphotyrosine binding (PTB) domain, reducing the secretion of cellular Beta-APP and slowing Beta-APP processing pathways. X11 binds specifically to the YENPTY motif, which is involved in the internalization of Beta-APP. Multiple splice varitents of X11 have been identified, including X11å (also designated Mint 1), X11Beta (Mint 2) and X11(Mint 3).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2396R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2396R-A488
Lokale Artikelnummer::
BOSSBS-2396R-A488
Beschreibung:
Catalyzes the methylation of glycine by using S-adenosylmethionine (AdoMet) to form N-methylglycine (sarcosine) with the concomitant production of S-adenosylhomocysteine (AdoHcy). Possible crucial role in the regulation of tissue concentration of AdoMet and of metabolism of methionine.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6594R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6594R-HRP
Lokale Artikelnummer::
BOSSBS-6594R-HRP
Beschreibung:
May regulate apoptosis, cell proliferation and cell differentiation. Binds beta-galactoside and a wide array of complex carbohydrates. Inhibits CD45 protein phosphatase activity and therefore the dephosphorylation of Lyn kinase. Strong inducer of T-cell apoptosis.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4103R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4103R
Lokale Artikelnummer::
BOSSBS-4103R
Beschreibung:
eIF4B is required for the binding of mRNA to ribosomes. It functions in close association with eIF4F and eIF4A. It binds near the 5'-terminal cap of mRNA in the presence of eIF4F and ATP. It promotes the ATPase activity and the ATP-dependent RNA unwinding activity of both eIF4A and eIF4F.
VE:
1 * 100 µl
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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