(Methylsulphonyl)methanesulphonyl+chloride
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
Ethyl-5-oxazolcarboxylat
Lieferant:
Alfa Aesar
Beschreibung:
Ethyl-2-chlornicotinat ≥98%
Lieferant:
Alfa Aesar
Beschreibung:
Ethyl-2-chlorbenzoat ≥98%
Artikel-Nr:
(H61701.06)
Lieferant:
Alfa Aesar
Hersteller-Artikelnummer::
H61701.06
Lokale Artikelnummer::
ALFAH61701.06
Beschreibung:
Ethyl-6-chlorpicolinat ≥97%
VE:
1 * 5 g
Artikel-Nr:
(BLDPBD218384-100MG)
Lieferant:
BLD PHARMATECH GMBH
Hersteller-Artikelnummer::
BD218384-100MG
Lokale Artikelnummer::
BLDPBD218384-100MG
Beschreibung:
Ethyl 4-ethoxypicolinate 97%
VE:
1 * 100 mg
Artikel-Nr:
(APOSPC201315-100MG)
Lieferant:
APOLLO SCIENTIFIC
Hersteller-Artikelnummer::
PC201315-100MG
Lokale Artikelnummer::
APOSPC201315-100MG
Beschreibung:
4-Ethyl-2-fluoroaniline 95+%
VE:
1 * 100 mg
Artikel-Nr:
(APOSOR4132-1G)
Lieferant:
APOLLO SCIENTIFIC
Hersteller-Artikelnummer::
OR4132-1G
Lokale Artikelnummer::
APOSOR4132-1G
Beschreibung:
N-Ethyl-4-boronobenzolsulfonamid 97%
VE:
1 * 1 g
Artikel-Nr:
(BLDPBD246489-1G)
Lieferant:
BLD PHARMATECH GMBH
Hersteller-Artikelnummer::
BD246489-1G
Lokale Artikelnummer::
BLDPBD246489-1G
Beschreibung:
N-Ethyl-2-morpholinoethanamine 95%
VE:
1 * 1 g
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
Ethyl 2-sulphamoylbenzoate
Artikel-Nr:
(07303-50MG)
Lieferant:
Sigma-Aldrich
Hersteller-Artikelnummer::
07303-50MG
Lokale Artikelnummer::
SUPL07303-50MG
Beschreibung:
Organic Standard, (2RS)-2-Ethyl-2-methylpentanoic acid
VE:
1 * 50 mg
Artikel-Nr:
(BOSSBS-12043R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12043R-HRP
Lokale Artikelnummer::
BOSSBS-12043R-HRP
Beschreibung:
Members of the paired homeobox family play a role in regulating cell development and pattern formation during embryonic stages. UNCX (UNC homeobox), also known as UNCX4.1, is a 531 amino acid nuclear transcription factor involved in neurogenesis and somitogenesis. Containing one homeobox DNA-binding domain, UNCX belongs to the paired homeobox family and UNC4 subfamily. UNCX assists in the formation of connections between hypothalamic neurons and the pituitary, which is necessary for central neurons to deliver hormones into peripheral blood. UNCX also plays a role in maintaining differentiation of the axial skeleton and acts upstream of Pax-9. The gene encoding UNCX maps to human chromosome 7, which houses over 1,000 genes and comprises nearly 5% of the human genome. Chromosome 7 has been linked to Osteogenesis imperfecta, Pendred syndrome, Lissencephaly, Citrullinemia and Shwachman-Diamond syndrome.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12143R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12143R-A488
Lokale Artikelnummer::
BOSSBS-12143R-A488
Beschreibung:
Major scaffold postsynaptic density protein which interacts with multiple proteins and complexes to orchestrate the dendritic spine and synapse formation, maturation and maintenance. Interconnects receptors of the postsynaptic membrane including NMDA-type and metabotropic glutamate receptors via complexes with GKAP/PSD-95 and HOMER, respectively, and the actin-based cytoskeleton. Plays a role in the structural and functional organization of the dendritic spine and synaptic junction through the interaction with Arp2/3 and WAVE1 complex as well as the promotion of the F-actin clusters. By way of this control of actin dynamics, participates in the regulation of developing neurons growth cone motility and the NMDA receptor-signaling. Also modulates GRIA1 exocytosis and GRM5/MGLUR5 expression and signaling to control the AMPA and metabotropic glutamate receptor-mediated synaptic transmission and plasticity. May be required at an early stage of synapse formation and be inhibited by IGF1 to promote synapse maturation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9076R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9076R-A750
Lokale Artikelnummer::
BOSSBS-9076R-A750
Beschreibung:
Cyclin dependent kinase 5 (Cdk5) is a key regulator of cell cycle progression in neuronal differentiation that physically associates with and is activated by the neuron-specific protein p35. CDK5RAP1 (CDK5 regulatory subunit-associated protein 1) specifically inhibits Cdk5 activation by p35 through formation of a dimer that inhibits kinase activity. CDK5RAP2, also known as Centrosome-associated protein 215, is a 1893 amino acid centrosomal protein that regulates activity of CDK5 through complex formation with CDK5RAP1. Expressed in placenta, liver, pancreas, heart, skeletal muscle, lung, brain and kidney, CDK5RAP2 associates with centrosomes throughout the cell cycle. Mutations in the gene encoding CDK5RAP2 results in primary microencephaly autosomal recessive type 3, which is characterised by markedly reduced head sise, brain weight and significant neurological deficits. There are four isoforms of CDK5RAP2 that are produced as a result of alternative splicing events.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13067R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13067R-A555
Lokale Artikelnummer::
BOSSBS-13067R-A555
Beschreibung:
Serum response factor (SRF) is a transcription factor that binds the serum response element (SRE), a sequence that mediates the transient response of many cellular genes to growth stimulation. SRF-binding sites are also constitutive promoter elements in many muscle-specific promoters. At the c-Fos SRE, formation of a ternary complex containing SRF and its accessory protein p62TCF appears to be important for signal transduction. Two related Ets domain proteins, Elk-1 and SRF accessory protein-1 (SAP-1), have DNA binding properties identical to that of p62TCF. Elk-1 and SAP-1 contain two homologous regions of which the two amino terminal regions, the Ets domain (box A) and the B box, mediate ternary complex formation with SRF. The third homologous region, the C box located toward the C-terminus of the proteins, contains conserved consensus phosphorylation sites for MAP kinases.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8998R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8998R-CY5.5
Lokale Artikelnummer::
BOSSBS-8998R-CY5.5
Beschreibung:
The initiation of DNA replication is a multi-step process that depends on the formation of pre-replication complexes, which trigger initiation (1). Among the proteins required for establishing these complexes are the origin recognition complex (ORC) proteins (1). ORC proteins bind specifically to origins of replication where they serve as scaffold for the assembly of additional initiation factors (1). Human ORC subunits 1-6 are expressed in the nucleus of proliferating cells and tissues, such as the testis (2). ORC1 and ORC2 are both expressed at equivalent concentrations throughout the cell cycle; however, only ORC2 remains stably bound to chromatin (3,4). ORC4 and ORC6 are also expressed constantly throughout the cell cycle (5,6). ORC2, ORC3, ORC4 and ORC5 form a core complex upon which ORC6 and ORC1 assemble (7,8). The formation of this core complex suggests that ORC proteins play a crucial role in the G1-S transition in mammalian cells (8).
VE:
1 * 100 µl
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