Drucken

Mouse recombinant CD40

Lieferant: PROSCI
Ratings: (keine Bewertung)

Gesamtbewertung: 0
Bewertung: von 5

92-602
PRSI92-602EA 461 EUR
PRSI92-602
Mouse recombinant CD40
Proteine und Peptide

CD40 is a Type I Transmembrane Glycoprotein that belongs to the TNF Receptor Superfamily. CD40 is expressed in B cells, follicular dendritic cells, dendritic cells, activated monocytes, macrophages, endothelial cells, vascular smooth muscle cells, and several tumor cell lines. The extracellular domain of CD40 is characterised by Cysteine rich repeat regions. Interaction of CD40 with its ligand (CD40L) leads to aggregation of CD40 molecules, which in turn interact with cytoplasmic components to initiate signalling pathways. Several different TRAF proteins (adaptor proteins) have been identified to serves as mediators of the signal transduction. CD40 plays an essential role in mediating a broad variety of immune and inflammatory responses including T cell-dependent immunoglobulin class switching, memory B cell development, and germinal center formation.


Fusion-Tag: C-Fc tag


This recombinant protein can be used for biological assays. For research use only.

Order Now


Learn more

About VWR

Avantor is a vertically integrated, global supplier of discovery-to-delivery solutions for...

Mehr About VWR