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Bis(lauroyloxy)dioctyltin
Artikel-Nr:
(BOSSBS-11712R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11712R
Lokale Artikelnummer::
BOSSBS-11712R
Beschreibung:
The charged multivesicular body proteins, commonly designated CHMPs, belong to the vacuolar sorting protein family and function as chromatin-modifying proteins. CHMP1-6 are all components of ESCRT (endosomal sorting complex required for transport) I, II or III complexes. These complexes are crucial for sorting endosomal articles into multivesicular bodies (MVBs), and are also required for the formation of these bodies. CHMP2B, also known as CHMP2.5 or vacuolar protein-sorting-associated protein 2-2, is a 213 amino acid cytosolic protein. Widely expressed in brain, heart, skeletal muscle, small intestine, pancreas, lung, placenta and leukocytes, CHMP2B associates directly with CHMP2A and vps4 for the disassembly of the ESCRT-III complex. Defects in the gene encoding CHMP2B have been shown to cause chromosome 3-linked frontotemporal dementia (FTD3).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1913R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1913R-A555
Lokale Artikelnummer::
BOSSBS-1913R-A555
Beschreibung:
Matrix Metalloproteinase 8 (MMP8) is also known as neutrophil collagenase and collagenase 2. MMP8 degrades fibrillar collagens types I, II, III, aggrecan, serpins and alpha 2 macroglobulin. All collagenases cleave fibrillar collagens at one specific site resulting in generation of N terminal three quarter and C terminal one quarter fragments, which then denature to gelatin at body temperature. The substrate specificity of collagenases is variable: MMP1 degrades type III collagen more efficiently than type I or type II collagen, whereas MMP8 is more potent in degrading type I collagen than type III or type II collagen. MMP13, in turn degrades type II collagen 6 fold more efficiently than type I and type II collagens and displays almost 50 fold stronger gelatinolytic activity than MMP1 and MMP8. MMP8 is very similar to MMP1, sharing 57 % amino acid identity. Most cell types do not produce MMP8. Until recently, it was thought that MMP8 was produced exclusively by neutrophils, but it has also been detected in other cell types including arthritic chondrocytes and gingival fibroblasts. The human MMP8 gene has the chromosomal location of 11q22.2-22.3. MMP8 is heavily glycosylated, and the zymogen has a mass of 85 Kd. The zymogen is quickly activated to the 64 Kd form, and this breaks down to a cascade of active forms.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1913R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1913R-HRP
Lokale Artikelnummer::
BOSSBS-1913R-HRP
Beschreibung:
Matrix Metalloproteinase 8 (MMP8) is also known as neutrophil collagenase and collagenase 2. MMP8 degrades fibrillar collagens types I, II, III, aggrecan, serpins and alpha 2 macroglobulin. All collagenases cleave fibrillar collagens at one specific site resulting in generation of N terminal three quarter and C terminal one quarter fragments, which then denature to gelatin at body temperature. The substrate specificity of collagenases is variable: MMP1 degrades type III collagen more efficiently than type I or type II collagen, whereas MMP8 is more potent in degrading type I collagen than type III or type II collagen. MMP13, in turn degrades type II collagen 6 fold more efficiently than type I and type II collagens and displays almost 50 fold stronger gelatinolytic activity than MMP1 and MMP8. MMP8 is very similar to MMP1, sharing 57 % amino acid identity. Most cell types do not produce MMP8. Until recently, it was thought that MMP8 was produced exclusively by neutrophils, but it has also been detected in other cell types including arthritic chondrocytes and gingival fibroblasts. The human MMP8 gene has the chromosomal location of 11q22.2-22.3. MMP8 is heavily glycosylated, and the zymogen has a mass of 85 Kd. The zymogen is quickly activated to the 64 Kd form, and this breaks down to a cascade of active forms.
VE:
1 * 100 µl
Artikel-Nr:
(39807.LA)
Lieferant:
Alfa Aesar
Hersteller-Artikelnummer::
39807.LA
Lokale Artikelnummer::
ALFA39807.LA
Beschreibung:
Aluminiumoxid Polierpaste
VE:
1 * 1 ST
Artikel-Nr:
(BOSSBS-0424R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0424R-A488
Lokale Artikelnummer::
BOSSBS-0424R-A488
Beschreibung:
Cleaves collagens of types I, II, and III at one site in the helical domain. Also cleaves collagens of types VII and X. In case of HIV infection, interacts and cleaves the secreted viral Tat protein, leading to a decrease in neuronal Tat's mediated neurotoxicity.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3844R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3844R-A750
Lokale Artikelnummer::
BOSSBS-3844R-A750
Beschreibung:
Hemidesmosomes are structures which link the basal lamina to the intermediate filament cytoskeleton. An important functional component of hemidesmosomes is the integrin beta-4 subunit (ITGB4), a protein containing two fibronectin type III domains. The protein encoded by Intergrin beta 4 binding protein binds to the fibronectin type III domains of ITGB4 and may help link ITGB4 to the intermediate filament cytoskeleton. The encoded protein, which is insoluble and found both in the nucleus and in the cytoplasm, can function as a translation initiation factor and prevent the association of the 40S and 60S ribosomal subunits. Multiple transcript variants encoding several different isoforms have been found for this gene.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1091R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1091R-A555
Lokale Artikelnummer::
BOSSBS-1091R-A555
Beschreibung:
Constitutive NADPH oxidase which generates superoxide intracellularly upon formation of a complex with CYBA/p22phox. Regulates signaling cascades probably through phosphatases inhibition. May function as an oxygen sensor regulating the KCNK3/TASK-1 potassium channel and HIF1A activity. May regulate insulin signaling cascade. May play a role in apoptosis, bone resorption and lipolysaccharide-mediated activation of NFKB.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1091R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1091R-FITC
Lokale Artikelnummer::
BOSSBS-1091R-FITC
Beschreibung:
Constitutive NADPH oxidase which generates superoxide intracellularly upon formation of a complex with CYBA/p22phox. Regulates signaling cascades probably through phosphatases inhibition. May function as an oxygen sensor regulating the KCNK3/TASK-1 potassium channel and HIF1A activity. May regulate insulin signaling cascade. May play a role in apoptosis, bone resorption and lipolysaccharide-mediated activation of NFKB.
VE:
1 * 100 µl
Artikel-Nr:
(46126.30)
Lieferant:
Alfa Aesar
Hersteller-Artikelnummer::
46126.30
Lokale Artikelnummer::
ALFA46126.30
Beschreibung:
Aluminiumoxid, Drysphere® trocknungsfördernd, mit Indikator 20%
VE:
1 * 250 g
Artikel-Nr:
(BOSSBS-1873R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1873R-A488
Lokale Artikelnummer::
BOSSBS-1873R-A488
Beschreibung:
Cleaves C-terminal amino acids linked to proline in peptides such as angiotensin II, III and des-Arg9-bradykinin. This cleavage occurs at acidic pH, but enzymatic activity is retained with some substrates at neutral pH.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1873R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1873R-A680
Lokale Artikelnummer::
BOSSBS-1873R-A680
Beschreibung:
Cleaves C-terminal amino acids linked to proline in peptides such as angiotensin II, III and des-Arg9-bradykinin. This cleavage occurs at acidic pH, but enzymatic activity is retained with some substrates at neutral pH.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1873R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1873R-A555
Lokale Artikelnummer::
BOSSBS-1873R-A555
Beschreibung:
Cleaves C-terminal amino acids linked to proline in peptides such as angiotensin II, III and des-Arg9-bradykinin. This cleavage occurs at acidic pH, but enzymatic activity is retained with some substrates at neutral pH.
VE:
1 * 100 µl
Artikel-Nr:
(USBI037305-PE)
Lieferant:
US Biological
Hersteller-Artikelnummer::
037305-PE
Lokale Artikelnummer::
USBI037305-PE
Beschreibung:
Anti-KCND1 Rabbit Polyclonal Antibody (PE (Phycoerythrin))
VE:
1 * 200 µl
Artikel-Nr:
(USBI037302-PE)
Lieferant:
US Biological
Hersteller-Artikelnummer::
037302-PE
Lokale Artikelnummer::
USBI037302-PE
Beschreibung:
Anti-KCNC2 Rabbit Polyclonal Antibody (PE (Phycoerythrin))
VE:
1 * 200 µl
Artikel-Nr:
(USBI037297-AP)
Lieferant:
US Biological
Hersteller-Artikelnummer::
037297-AP
Lokale Artikelnummer::
USBI037297-AP
Beschreibung:
Anti-KCNA6 Rabbit Polyclonal Antibody (AP (Alkaline Phosphatase))
VE:
1 * 200 µl
Artikel-Nr:
(BOSSBS-1850R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1850R-CY3
Lokale Artikelnummer::
BOSSBS-1850R-CY3
Beschreibung:
Receptor for both mineralocorticoids (MC) such as aldosterone and glucocorticoids (GC) such as corticosterone or cortisol. Binds to mineralocorticoid response elements (MRE) and transactivates target genes. The effect of MC is to increase ion and water transport and thus raise extracellular fluid volume and blood pressure and lower potassium levels.
VE:
1 * 100 µl
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Dieses Produkt kann nur an eine Lieferadresse versandt werden die über die entsprechende Lizenzen verfügt. Für weitere Hilfe bitte kontaktieren Sie Ihr VWR Vertriebszentrum.
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Dieses Produkt ist Ersatz für den von Ihnen gewünschten Artikel.
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