6-Formylpicolinonitrile
Artikel-Nr:
(BOSSBS-12567R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12567R-A555
Lokale Artikelnummer::
BOSSBS-12567R-A555
Beschreibung:
Bad is a member of the Bcl2 family and acts to promote apoptosis by forming heterodimers with the survival proteins Bcl2 and BclxL, thus preventing them from binding with BAX. Bad is found on the outer mitochondrial membrane and, once phosphorylated in response to growth stimuli, translocates to the cytoplasm. The phosphorylation status of Bad represents a key checkpoint for death or cell survival. JNK-induced phosphorylation of BAD serine 128 promotes the apoptotic role of Bad by opposing the inhibitory effect of growth factor on Bad-mediated apoptosis. Cdc2-induced phosphorylation of Bad serine 128 has an inhibitory effect on its interaction with 14-3-3 proteins. The latter interaction is critical for Bad phosphorylation at serine 155, a site within the BH3 domain that leads to the release of BclxL and the promotion of cell survival. Alternative splicing of this gene results in two transcript variants which encode the same isoform.This antibody recognise the phosphorylation site of human Ser75, mouse Ser111, rat Ser112.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3655R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3655R-CY7
Lokale Artikelnummer::
BOSSBS-3655R-CY7
Beschreibung:
This gene is a member of the kernel lipocalin superfamily whose members share relatively low sequence similarity but have highly conserved exon/intron structure and three-dimensional protein folding. Most lipocalins are clustered on the long arm of chromosome 9. The encoded glycoprotein has been previously referred to as pregnancy-associated endometrial alpha-2-globulin, placental protein 14, and glycodelin, but has been officially named progestagen-associated endometrial protein. Three distinct forms, with identical protein backbones but different glycosylation profiles, are found in amniotic fluid, follicular fluid and seminal plasma of the reproductive system. These glycoproteins have distinct and essential roles in regulating a uterine environment suitable for pregnancy and in the timing and occurrence of the appropriate sequence of events in the fertilization process. A number of alternatively spliced transcript variants have been observed at this locus, but the full-length nature of only two, each encoding the same protein, has been determined. [provided by RefSeq].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3655R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3655R-FITC
Lokale Artikelnummer::
BOSSBS-3655R-FITC
Beschreibung:
This gene is a member of the kernel lipocalin superfamily whose members share relatively low sequence similarity but have highly conserved exon/intron structure and three-dimensional protein folding. Most lipocalins are clustered on the long arm of chromosome 9. The encoded glycoprotein has been previously referred to as pregnancy-associated endometrial alpha-2-globulin, placental protein 14, and glycodelin, but has been officially named progestagen-associated endometrial protein. Three distinct forms, with identical protein backbones but different glycosylation profiles, are found in amniotic fluid, follicular fluid and seminal plasma of the reproductive system. These glycoproteins have distinct and essential roles in regulating a uterine environment suitable for pregnancy and in the timing and occurrence of the appropriate sequence of events in the fertilization process. A number of alternatively spliced transcript variants have been observed at this locus, but the full-length nature of only two, each encoding the same protein, has been determined. [provided by RefSeq].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3655R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3655R-A647
Lokale Artikelnummer::
BOSSBS-3655R-A647
Beschreibung:
This gene is a member of the kernel lipocalin superfamily whose members share relatively low sequence similarity but have highly conserved exon/intron structure and three-dimensional protein folding. Most lipocalins are clustered on the long arm of chromosome 9. The encoded glycoprotein has been previously referred to as pregnancy-associated endometrial alpha-2-globulin, placental protein 14, and glycodelin, but has been officially named progestagen-associated endometrial protein. Three distinct forms, with identical protein backbones but different glycosylation profiles, are found in amniotic fluid, follicular fluid and seminal plasma of the reproductive system. These glycoproteins have distinct and essential roles in regulating a uterine environment suitable for pregnancy and in the timing and occurrence of the appropriate sequence of events in the fertilization process. A number of alternatively spliced transcript variants have been observed at this locus, but the full-length nature of only two, each encoding the same protein, has been determined. [provided by RefSeq].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9684R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9684R-A555
Lokale Artikelnummer::
BOSSBS-9684R-A555
Beschreibung:
C19orf54 is a 351 amino acid protein that exists as two alternatively spliced isoforms and are encoded by a gene located on human chromosome 19. Chromosome 19 consists of approximately 63 million bases and makes up over 2% of human genomic DNA. Chromosome 19 includes a diversity of interesting genes and is recognized for having the greatest gene density of the human chromosomes. It is the genetic home for a number of immunoglobulin superfamily members including the killer cell and leukocyte Ig-like receptors, a number of ICAMs, the CEACAM and PSG family, and Fcα receptors. Key genes for eye color and hair color also map to chromosome 19. Peutz-Jeghers syndrome, spinocerebellar ataxia type 6, the stroke disorder CADASIL, hypercholesterolemia and insulin-dependent diabetes have been linked to chromosome 19. Translocations with chromosome 19 and chromosome 14 can be seen in some lymphoproliferative disorders and typically involve the proto-oncogene BCL3.
VE:
1 * 100 µl
Artikel-Nr:
(PRSI24-629)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
24-629
Lokale Artikelnummer::
PRSI24-629
Beschreibung:
Anti-Timd2 Recombinant Antibody [Clone: RMT2-14]
VE:
1 * 0,2 mg
New Product
Artikel-Nr:
(ORIGTA320363)
Lieferant:
OriGene
Hersteller-Artikelnummer::
TA320363
Lokale Artikelnummer::
ORIGTA320363
Beschreibung:
Anti-IL1A Mouse Polyclonal Antibody [clone: 364/3B3-14]
VE:
1 * 50 µG
Artikel-Nr:
(VARIPL3476-6689)
Lieferant:
VARIAN
Hersteller-Artikelnummer::
PL3476-6689
Lokale Artikelnummer::
VARIPL3476-6689
Beschreibung:
PL-FMPB resin, 1% DVB, 1,4 mmol/g, 150 - 300 μm, 1 kg
VE:
1 * 1 ST
Lieferant:
Restek
Beschreibung:
Organic Standard, 1,4-Dichlorbenzol 1.000 µg/ml in Acetonitril, Packung: Glasampulle
Artikel-Nr:
(BOSSBS-9258R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9258R-CY5.5
Lokale Artikelnummer::
BOSSBS-9258R-CY5.5
Beschreibung:
The RING-type zinc finger motif is present in a number of viral and eukaryotic proteins and is made of a conserved cysteine-rich domain that is able to bind two zinc atoms. Proteins that contain this conserved domain are generally involved in protein-protein interactions and protein-DNA interactions. Specifically, they are thought to be involved in the ubiquitination pathway of protein degradation. RNF165 (RING finger protein 165) is a 346 amino acid protein that contains one RING-type zinc finger. Via its RING-type zinc finger, RNF165 may play a role in transcriptional regulation and protein degradation events. The gene encoding RNF165 maps to human chromosome 18, which houses over 300 genes, including Trisomy 18, or Edwards syndrome, the second most common trisomy after Downs syndrome. Translocation between chromosome 18 and 14 is the most common translocation in cancers, and occurs in follicular lymphomas. Niemann-Pick disease, hereditary hemorrhagic telangiectasia and erythropoietic protoporphyria are also associated with chromosome 18.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11477R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11477R-A488
Lokale Artikelnummer::
BOSSBS-11477R-A488
Beschreibung:
Semaphorins are a family of cell surface and secreted proteins that are conserved from insects to humans. Members of this family of proteins are approximately 750 amino acids in length (including signal sequences) and are defined by a conserved extracellular “semaphorin†domain of approximately 500 amino acids containing 14-16 cysteines, blocks of conserved sequences and no obvious repeats. The transmembrane semaphorins are characterized by an additional 80 amino acid transmembrane domain and an 80-110 amino acid cytoplasmic domain. Secreted and cell-bound semaphorins chemically attract and repel the growth of neural axons, guiding the development of intricate networks of neural tissue. SEMA4B (semaphorin-4B), also known as SemC or SEMAC, is an 832 amino acid single-pass type I membrane protein that belongs to the semaphorin family and exists as two alternatively spliced isoforms. Containing one Ig-like C2-type (immunoglobulin-like) domain, a PSI domain and a single sema domain, SEMA4B is encoded by a gene located on human chromosome 15.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11477R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11477R-CY5
Lokale Artikelnummer::
BOSSBS-11477R-CY5
Beschreibung:
Semaphorins are a family of cell surface and secreted proteins that are conserved from insects to humans. Members of this family of proteins are approximately 750 amino acids in length (including signal sequences) and are defined by a conserved extracellular “semaphorin†domain of approximately 500 amino acids containing 14-16 cysteines, blocks of conserved sequences and no obvious repeats. The transmembrane semaphorins are characterized by an additional 80 amino acid transmembrane domain and an 80-110 amino acid cytoplasmic domain. Secreted and cell-bound semaphorins chemically attract and repel the growth of neural axons, guiding the development of intricate networks of neural tissue. SEMA4B (semaphorin-4B), also known as SemC or SEMAC, is an 832 amino acid single-pass type I membrane protein that belongs to the semaphorin family and exists as two alternatively spliced isoforms. Containing one Ig-like C2-type (immunoglobulin-like) domain, a PSI domain and a single sema domain, SEMA4B is encoded by a gene located on human chromosome 15.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11477R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11477R
Lokale Artikelnummer::
BOSSBS-11477R
Beschreibung:
Semaphorins are a family of cell surface and secreted proteins that are conserved from insects to humans. Members of this family of proteins are approximately 750 amino acids in length (including signal sequences) and are defined by a conserved extracellular “semaphorin†domain of approximately 500 amino acids containing 14-16 cysteines, blocks of conserved sequences and no obvious repeats. The transmembrane semaphorins are characterized by an additional 80 amino acid transmembrane domain and an 80-110 amino acid cytoplasmic domain. Secreted and cell-bound semaphorins chemically attract and repel the growth of neural axons, guiding the development of intricate networks of neural tissue. SEMA4B (semaphorin-4B), also known as SemC or SEMAC, is an 832 amino acid single-pass type I membrane protein that belongs to the semaphorin family and exists as two alternatively spliced isoforms. Containing one Ig-like C2-type (immunoglobulin-like) domain, a PSI domain and a single sema domain, SEMA4B is encoded by a gene located on human chromosome 15.
VE:
1 * 100 µl
Artikel-Nr:
(PRSI24-173)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
24-173
Lokale Artikelnummer::
PRSI24-173
Beschreibung:
Anti-INSR Recombinant Antibody [Clone: 83-14]
VE:
1 * 0,2 mg
New Product
Artikel-Nr:
(PROOCILULM78401.2)
Lieferant:
LGC Standards PROMOCHEM
Hersteller-Artikelnummer::
CILULM78401.2
Lokale Artikelnummer::
PROOCILULM78401.2
Beschreibung:
Organic Standard, 1,4-Dioxan 1.000 µg/ml in Methanol, Packung: Glasflasche
VE:
1 * 1,2 mL
Lieferant:
MEMMERT
Beschreibung:
Klammer für 14×300 ml Flasche max., Für: WTB35
Preis auf Anfrage
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