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Antikörper
Lieferant:
Biotium
Beschreibung:
Recognizes a 67 kDa glycoprotein, which is identified as CD33. It is a transmembrane protein of the sialic acid-binding immunoglobulin-like lectin (Siglec) family. It belongs to the immunoreceptor tyrosine-based inhibitory motif (ITIM)-containing molecules able of recruiting protein tyrosine phosphatases SHP-1 and SHP-2 to signal assemblies; these ITIMs are also used for ubiquitin-mediated removal of the receptor from the cell surface. CD33 is expressed on cells of myelomonocytic lineage, binds sialic acid residues in N- and O-glycans on cell surfaces, and is a therapeutic target for acute myeloid leukemia. CD33 is expressed on myeloid progenitors, monocytes, granulocytes, dendritic cells and mast cells. It is absent on platelets, lymphocytes, erythrocytes and hematopoietic stem cells.
Artikel-Nr:
(USBIC1035-26M)
Lieferant:
US Biological
Hersteller-Artikelnummer::
C1035-26M
Lokale Artikelnummer::
USBIC1035-26M
Beschreibung:
Anti-CANX Mouse Monoclonal Antibody [clone: 1D4]
VE:
1 * 50 µG
Artikel-Nr:
(BOSSBS-3928R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3928R
Lokale Artikelnummer::
BOSSBS-3928R
Beschreibung:
Anti-PAPK/ALS2CR2 Rabbit Polyclonal Antibody
VE:
1 * 100 µl
Artikel-Nr:
(AVIVARP35493_P050)
Lieferant:
Aviva Systems Biology
Hersteller-Artikelnummer::
ARP35493_P050
Lokale Artikelnummer::
AVIVARP35493_P050
Beschreibung:
Anti-KCNIP2 Rabbit Polyclonal Antibody
VE:
1 * 50 µG
Artikel-Nr:
(USBIE3375-35F-100)
Lieferant:
US Biological
Hersteller-Artikelnummer::
E3375-35F-100
Lokale Artikelnummer::
USBIE3375-35F-100
Beschreibung:
Anti-erbB Mouse Monoclonal Antibody [clone: 6D370]
VE:
1 * 100 µG
Lieferant:
Biotium
Beschreibung:
This MAb is specific to heavy chain of IgA and shows minimal cross-reaction with heavy chains of other immunoglobulins. It is reactive with both IgA1 and IgA2 subclasses of Alpha heavy chain. It reacts with the third constant domain (CH3) of the alpha chain of IgA molecules. Immunoglobulins are four-chain, Y-shaped, monomeric structures comprised of two identical heavy chains and two identical light chains held together through inter-chain disulfide bonds. The chains form two domains, the Fab (antigen binding) fragment and the Fc (constant) fragment. Immunoglobulin A (IgA) is the main protein of the mucosal immune system. It is generated by B-cells in gut-associated lymphoid tissues. Daily production of IgA exceeds that of any of the other immunoglobulins.IgA exists mainly in dimers but can also exist as polymers or as monomers. Dimers and polymers contain a joining (J) chain that can be bound by the polymeric immunoglobulin receptor (pIgR) for transportation of the molecule to mucosal surfaces. The most common feature of plasmacytomas, and certain non-Hodgkin's lymphomas is the restricted expression of a single heavy chain class. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is clonal and therefore malignant.
Artikel-Nr:
(USBI035752-HRP)
Lieferant:
US Biological
Hersteller-Artikelnummer::
035752-HRP
Lokale Artikelnummer::
USBI035752-HRP
Beschreibung:
Anti-FOXP1 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))
VE:
1 * 200 µl
Lieferant:
Biotium
Beschreibung:
This antibody recognizes a glycoprotein of 110 kDa, which is identified as CD68. It is important for identifying macrophages in tissue sections. It stains macrophages in a wide variety of human tissues, including Kupffer cells and macrophages in the red pulp of the spleen, in lamina propria of the gut, in lung alveoli, and in bone marrow. It reacts with myeloid precursors and peripheral blood granulocytes. It also reacts with plasmacytoid T cells, which are supposed to be of monocyte/macrophage origin. It shows strong granular cytoplasmic staining of chronic and acute myeloid leukemia and also reacts with rare cases of true histiocytic neoplasia. Lymphomas are negative or show few granules.
Artikel-Nr:
(USBI130101)
Lieferant:
US Biological
Hersteller-Artikelnummer::
130101
Lokale Artikelnummer::
USBI130101
Beschreibung:
Anti-KAT7 Rabbit Polyclonal Antibody
VE:
1 * 100 µG
Artikel-Nr:
(BOSSBS-3532R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3532R-A647
Lokale Artikelnummer::
BOSSBS-3532R-A647
Beschreibung:
The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. It is a crucial enzyme in transmembrane signaling.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5583R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5583R-FITC
Lokale Artikelnummer::
BOSSBS-5583R-FITC
Beschreibung:
This is a calcium-independent, phospholipid-dependent, serine- and threonine-specific enzyme. Essential for T-cell receptor (TCR)-mediated T-cell activation, but is dispensable during TCR-dependent thymocyte development. Links the TCR signaling complex to the activation of NF-kappa-B in mature T lymphocytes. Required for interleukin-2 (IL2) production. PKC is activated by diacylglycerol which in turn phosphorylates a range of cellular proteins. PKC also serves as the receptor for phorbol esters, a class of tumor promoters.
VE:
1 * 100 µl
Artikel-Nr:
(USBI037274-PE)
Lieferant:
US Biological
Hersteller-Artikelnummer::
037274-PE
Lokale Artikelnummer::
USBI037274-PE
Beschreibung:
Anti-KATL1 Rabbit Polyclonal Antibody (PE (Phycoerythrin))
VE:
1 * 200 µl
Artikel-Nr:
(BOSSBS-3459R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3459R-A750
Lokale Artikelnummer::
BOSSBS-3459R-A750
Beschreibung:
Tuberin, or TSC2 (Tuberous sclerosis complex), is implicated as a tumor suppressor. It may function in vesicular transport, and may also play a role in the regulation of cell growth arrest and in the regulation of transcription mediated by steroid receptors. Interaction between hamartin (TSC1) and tuberin may facilitate vesicular docking. It specifically stimulates the intrinsic GTPase activity of the Ras related protein RAP1A and RAB5, suggesting a possible mechanism for its role in regulating cellular growth. Mutations in tuberin lead to constitutive activation of RAP1A in tumors. At least three isoforms of Tuberin exist.
VE:
1 * 100 µl
Artikel-Nr:
(AVIVARP39078_P050)
Lieferant:
Aviva Systems Biology
Hersteller-Artikelnummer::
ARP39078_P050
Lokale Artikelnummer::
AVIVARP39078_P050
Beschreibung:
Anti-PATZ1 Rabbit Polyclonal Antibody
VE:
1 * 50 µG
Lieferant:
Biotium
Beschreibung:
This antibody recognizes an antigen associated with the nuclear membrane expressed in human cells. It can be used to stain the nuclear membrane in cell or tissue preparations and can be used as a marker of the nuclear membrane in subcellular fractions. It produces a ring pattern around the nucleus of cells of normal and malignant cells and may be used to stain the nuclear membrane of cells in fixed or frozen tissue sections. ,The nuclear envelope (also known as the perinuclear envelope, nuclear membrane, nucleolemma or karyotheca) is the double membrane of the nucleus that encloses genetic material in eukaryotic cells. It separates the contents of the nucleus (DNA in particular) from the cytosol (cytoplasm). Numerous nuclear pores are present on the nuclear envelope to facilitate and regulate the exchange of materials (for example, proteins and RNA) between the nucleus and the cytoplasm. The space between the two membranes that make up the nuclear envelope is called the perinuclear space (also called the perinuclear cisterna), and is usually about 20 - 40 nm wide. Each of the two membranes is composed of a lipid bilayer. The outer membrane is continuous with the rough endoplasmic reticulum. The inner membrane is erected upon the nuclear lamina, a network of intermediate filaments made of lamin, that plays a role in mitosis and meiosis. The type of lamins present are A, B1, B2, and C. The nuclear envelope may also play a role in the disposition of chromatin inside the nucleus. The lamina acts as a site of attachment for chromosomes. It also acts like a shield for the nucleus. During prophase in mitosis, the chromatids begin condensing to form chromosomes, and the nuclear envelope begins to disintegrate. During metaphase, the nuclear envelope is completely disintegrated, and the chromosomes can be pulled apart as chromatids by the spindle fibers.
Artikel-Nr:
(USBIG9000-19Z)
Lieferant:
US Biological
Hersteller-Artikelnummer::
G9000-19Z
Lokale Artikelnummer::
USBIG9000-19Z
Beschreibung:
Anti-Growth Hormone Releasing Factor Rabbit Polyclonal Antibody
VE:
1 * 200 µl
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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