Drucken
Sie suchten nach:
431 889 results were found
Antikörper
Artikel-Nr:
(BOSSBS-13286R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13286R-A555
Lokale Artikelnummer::
BOSSBS-13286R-A555
Beschreibung:
GARNL1 is expressed during embryogenesis with E12. During development, GARNL1 expression decreases, persisting at high levels only in neurons of the adult brain. GARNL1 localizes to the cytoplasm where it may play a role regulating GTP hydrolysis of proteins such as Ran and Rap. GARNL1 is imported to the nucleus via dimerization with E12. GARNL1 interacts with the HLH region of E12 and may function to negatively regulate the transcription of E12-dependent downstream target genes. This suggests that at least a portion of the function of GARNL1 is dependent upon its association with E12. GARNL1 may also associate with other HLH proteins and influence a variety of HLH signaling cascades. In adult brain, GARNL1 activity does not involve E12 and therefore it may serve a different function in developed neural tissue.
VE:
1 * 100 µl
Artikel-Nr:
(USBI033254-AP)
Lieferant:
US Biological
Hersteller-Artikelnummer::
033254-AP
Lokale Artikelnummer::
USBI033254-AP
Beschreibung:
Anti-CBX4 Rabbit Polyclonal Antibody (AP (Alkaline Phosphatase))
VE:
1 * 200 µl
Artikel-Nr:
(BOSSBS-11752R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11752R-A750
Lokale Artikelnummer::
BOSSBS-11752R-A750
Beschreibung:
Transport of G protein-coupled receptors (GPCRs) to the cell surface membrane is critical for receptor-ligand recognition. Mammalian GPCR odorant receptors (ORs), when heterologously expressed in cells, are poorly expressed on the cell surface. REEP1 (receptor expression-enhancing protein 1), is a 201 amino acid multi-pass mitochondrion membrane protein that belongs to the DP1 family. REEP1 interacts with odorant receptor proteins and may enhance the cell surface expression of odorant receptors. Mutations in the REEP1 gene are the third most common cause of hereditary spastic paraplegia (HSP) after spastin and atlastin gene mutations. Mutations in the REEP1 gene also cause spastic paraplegia autosomal dominant type 31, a neurodegenerative disorder. The REEP1 gene is conserved in chimpanzee, dog, cow, mouse, rat, chicken, zebrafish, A.thaliana and rice, and maps to human chromosome 2p11.2.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6427R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6427R-A750
Lokale Artikelnummer::
BOSSBS-6427R-A750
Beschreibung:
Putative E3 ubiquitin-protein ligase. May participate in methylation-dependent transcriptional regulation. Binds to inverted 5'-CCAAT-3' box 2 in the TOP2A promoter, and activates TOP2A expression. Important for G1/S transition. May be involved in DNA repair and chromosomal stability.Tissue specificity:Expressed in thymus, bone marrow, testis, lung and heart. Overexpressed in breast cancer. UHRF2 is an E3 ubiquitin-protein ligase that is an intermolecular hub protein in the cell cycle network. Through cooperative DNA and histone binding, may contribute to a tighter epigenetic control of gene expression in differentiated cells. Ubiquitinates cyclins, CCND1 and CCNE1, in an apparently phosphorylation-independent manner and induces G1 arrest. Also ubiquitinates PCNP leading to its degradation by the proteasome. E3 SUMO-, but not ubiquitin-, protein ligase for ZNF131.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5506R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5506R-A680
Lokale Artikelnummer::
BOSSBS-5506R-A680
Beschreibung:
The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation, and development. MAPK11 is most closely related to p38 MAP kinase, both of which can be activated by proinflammatory cytokines and environmental stress. This kinase is activated through its phosphorylation by MAP kinase kinases (MKKs), preferably by MKK6. Transcription factor ATF2/CREB2 has been shown to be a substrate of this kinase.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6283R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6283R-A750
Lokale Artikelnummer::
BOSSBS-6283R-A750
Beschreibung:
Sulfotransferase enzymes catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs, and xenobiotic compounds. These cytosolic enzymes are different in their tissue distributions and substrate specificities. The gene structure (number and length of exons) is similar among family members. This gene encodes one of two phenol sulfotransferases with thermostable enzyme activity. Multiple alternatively spliced variants that encode two isoforms have been identified for this gene.
VE:
1 * 100 µl
Artikel-Nr:
(USBI033996-APC)
Lieferant:
US Biological
Hersteller-Artikelnummer::
033996-APC
Lokale Artikelnummer::
USBI033996-APC
Beschreibung:
Anti-CLK2 Rabbit Polyclonal Antibody (APC (Allophycocyanin))
VE:
1 * 200 µl
Artikel-Nr:
(USBI123365)
Lieferant:
US Biological
Hersteller-Artikelnummer::
123365
Lokale Artikelnummer::
USBI123365
Beschreibung:
Anti-ANXA5 Rabbit Polyclonal Antibody
VE:
1 * 100 µl
Artikel-Nr:
(BWRLBS3850)
Lieferant:
Bioworld Technology
Hersteller-Artikelnummer::
BS3850
Lokale Artikelnummer::
BWRLBS3850
Beschreibung:
Synthetic peptide, corresponding to amino acids 1060-1110 of Human DNA pol delta cat.
VE:
1 * 100 µG
Artikel-Nr:
(BOSSBS-0638R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0638R-CY3
Lokale Artikelnummer::
BOSSBS-0638R-CY3
Beschreibung:
Transmembrane serine/threonine kinase forming with the TGF-beta type II serine/threonine kinase receptor, TGFBR2, the non-promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinogenesis. The formation of the receptor complex composed of 2 TGFBR1 and 2 TGFBR2 molecules symmetrically bound to the cytokine dimer results in the phosphorylation and the activation of TGFBR1 by the constitutively active TGFBR2. Activated TGFBR1 phosphorylates SMAD2 which dissociates from the receptor and interacts with SMAD4. The SMAD2-SMAD4 complex is subsequently translocated to the nucleus where it modulates the transcription of the TGF-beta-regulated genes. This constitutes the canonical SMAD-dependent TGF-beta signaling cascade. Also involved in non-canonical, SMAD-independent TGF-beta signaling pathways. For instance, TGFBR1 induces TRAF6 autoubiquitination which in turn results in MAP3K7 ubiquitination and activation to trigger apoptosis. Also regulates epithelial to mesenchymal transition through a SMAD-independent signaling pathway through PARD6A phosphorylation and activation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2521R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2521R-A350
Lokale Artikelnummer::
BOSSBS-2521R-A350
Beschreibung:
Plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0056R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0056R-A680
Lokale Artikelnummer::
BOSSBS-0056R-A680
Beschreibung:
Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.
VE:
1 * 100 µl
Artikel-Nr:
(USBI034064-PE)
Lieferant:
US Biological
Hersteller-Artikelnummer::
034064-PE
Lokale Artikelnummer::
USBI034064-PE
Beschreibung:
Anti-CO040 Rabbit Polyclonal Antibody (PE (Phycoerythrin))
VE:
1 * 200 µl
Artikel-Nr:
(AVIVP101699_T100)
Lieferant:
Aviva Systems Biology
Hersteller-Artikelnummer::
P101699_T100
Lokale Artikelnummer::
AVIVP101699_T100
Beschreibung:
Anti-NUCB1 Rabbit Polyclonal Antibody
VE:
1 * 100 µG
Artikel-Nr:
(USBI039245-FITC)
Lieferant:
US Biological
Hersteller-Artikelnummer::
039245-FITC
Lokale Artikelnummer::
USBI039245-FITC
Beschreibung:
Anti-OBFC1 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))
VE:
1 * 200 µl
Artikel-Nr:
(USBIT1041-04E-PE)
Lieferant:
US Biological
Hersteller-Artikelnummer::
T1041-04E-PE
Lokale Artikelnummer::
USBIT1041-04E-PE
Beschreibung:
Anti-MAPT Rabbit Polyclonal Antibody (PE (Phycoerythrin))
VE:
1 * 200 µl
Preis auf Anfrage
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Dieses Produkt kann nur an eine Lieferadresse versandt werden die über die entsprechende Lizenzen verfügt. Für weitere Hilfe bitte kontaktieren Sie Ihr VWR Vertriebszentrum.
-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
Dieses Produkt wurde von Ihrer Organisation gesperrt. Bitte kontaktieren Sie Ihren Einkauf für weitere Informationen.
Dieses Produkt ist Ersatz für den von Ihnen gewünschten Artikel.
Dieses Produkt ist nicht mehr verfügbar. Bitte kontaktieren Sie den VWR Kundenservice.
|
|||||||||
Listenansicht
