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432 382 results were found
Antikörper
Artikel-Nr:
(BOSSBS-9748R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9748R-CY7
Lokale Artikelnummer::
BOSSBS-9748R-CY7
Beschreibung:
Ankyrins are membrane adaptor molecules that play important roles in coupling integral membrane proteins to the spectrin-based cytoskeleton network. Mutations of ankyrin genes lead to severe genetic diseases, such as fatal cardiac arrhythmias and hereditary spherocytosis. ANKRD22 (ankyrin repeat domain 22) is a 191 amino acid protein that contains four ANK repeats. Conserved in chimpanzee, dog, cow, mouse, rat, chicken and zebrafish, ANKRD22 is encoded by a gene that maps to human chromosome 10. Chromosome 10 encodes nearly 1,200 genes within 135 million bases, making up approximately 4.5% of the human genome. Several protein-coding genes, including those that encode for chemokines, cadherins, excision repair proteins, early growth response factors (Egrs) and fibroblast growth receptors (FGFRs), are located on chromosome 10. Defects in genes that map to chromosome 10 are associated with Charcot-Marie Tooth disease, Jackson-Weiss syndrome, Usher syndrome, nonsyndromatic deafness, Wolman’s syndrome, Cowden syndrome, multiple endocrine neoplasia type 2 and porphyria.
VE:
1 * 100 µl
Artikel-Nr:
(USBIT1080-10A)
Lieferant:
US Biological
Hersteller-Artikelnummer::
T1080-10A
Lokale Artikelnummer::
USBIT1080-10A
Beschreibung:
Anti-TAZ Rabbit Polyclonal Antibody
VE:
1 * 200 µl
Artikel-Nr:
(USBI035856-APC)
Lieferant:
US Biological
Hersteller-Artikelnummer::
035856-APC
Lokale Artikelnummer::
USBI035856-APC
Beschreibung:
Anti-GABRA4 Rabbit Polyclonal Antibody (APC (Allophycocyanin))
VE:
1 * 200 µl
Artikel-Nr:
(USBII8600-18B)
Lieferant:
US Biological
Hersteller-Artikelnummer::
I8600-18B
Lokale Artikelnummer::
USBII8600-18B
Beschreibung:
Anti-IRAK4 Rabbit Polyclonal Antibody
VE:
1 * 100 µG
Artikel-Nr:
(USBIT8663-01H-FITC)
Lieferant:
US Biological
Hersteller-Artikelnummer::
T8663-01H-FITC
Lokale Artikelnummer::
USBIT8663-01H-FITC
Beschreibung:
Anti-NTRK1 Rabbit Polyclonal Antibody (FITC (Fluorescein))
VE:
1 * 200 µl
Artikel-Nr:
(USBIP9107-18D-FITC)
Lieferant:
US Biological
Hersteller-Artikelnummer::
P9107-18D-FITC
Lokale Artikelnummer::
USBIP9107-18D-FITC
Beschreibung:
Anti-PPP1CC Rabbit Polyclonal Antibody (FITC (Fluorescein))
VE:
1 * 200 µl
Artikel-Nr:
(BOSSBS-13575R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13575R-CY7
Lokale Artikelnummer::
BOSSBS-13575R-CY7
Beschreibung:
Chromosome 1 is the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The mechanism of rapidly enhanced aging is unclear and is a topic of continuing exploration. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1. A breakpoint has been identified in 1q which disrupts the DISC1 gene and is linked to schizophrenia. Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, malignant melanoma and multiple myeloma.
VE:
1 * 100 µl
Artikel-Nr:
(ROCK012-006-041)
Lieferant:
Rockland Immunochemicals
Hersteller-Artikelnummer::
012-006-041
Lokale Artikelnummer::
ROCK012-006-041
Beschreibung:
Rat IgG2a isotype control can be utilized as a control or standard reagent in Western Blotting, Flow Cytometry, and ELISA experiments where determination of sample isotype is important. Specific conditions should be optimized by user.
VE:
1 * 50 µG
Artikel-Nr:
(BOSSBS-5777R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5777R-CY7
Lokale Artikelnummer::
BOSSBS-5777R-CY7
Beschreibung:
Serine/threonine protein kinase which forms a receptor complex on ligand binding. The receptor complex consisting of 2 type II and 2 type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators, SMAD2 and SMAD3. Receptor for activin AB, activin B and NODAL. Plays a role in cell differentiation, growth arrest and apoptosis.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-10369R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-10369R-A647
Lokale Artikelnummer::
BOSSBS-10369R-A647
Beschreibung:
The protein encoded by this gene is secreted and then cleaved to form the 10 aa luteinizing hormone-releasing hormone (LHRH, also known as gonadoliberin-1), and prolactin release-inhibiting factor (also known as GnRH-associated peptide 1). LHRH stimulates the release of luteinizing and follicle stimulating hormones, which are important for reproduction. Mutation in this gene are associated with hypogonadotropic hypogonadism. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Jul 2012].
VE:
1 * 100 µl
Artikel-Nr:
(USBIR9700-24)
Lieferant:
US Biological
Hersteller-Artikelnummer::
R9700-24
Lokale Artikelnummer::
USBIR9700-24
Beschreibung:
Anti-Rubella, Strain HPV-77 Goat Polyclonal Antibody
VE:
1 * 1 mL
Artikel-Nr:
(BOSSBS-4589R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4589R-HRP
Lokale Artikelnummer::
BOSSBS-4589R-HRP
Beschreibung:
High density lipoprotein
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6389R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6389R-CY5.5
Lokale Artikelnummer::
BOSSBS-6389R-CY5.5
Beschreibung:
E3 ubiquitin-protein ligase which mediates ubiquitination and subsequent proteasomal degradation of PCNP. May participate in methylation-dependent transcriptional regulation. Important for G1/S transition. Overexpression causes G1 phase cell arrest.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4182R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4182R-CY5
Lokale Artikelnummer::
BOSSBS-4182R-CY5
Beschreibung:
As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. In the cellular response to DNA damage, the RPA complex controls DNA repair and DNA damage checkpoint activation. Through recruitment of ATRIP activates the ATR kinase a master regulator of the DNA damage response. It is required for the recruitment of the DNA double-strand break repair factors RAD51 and RAD52 to chromatin in response to DNA damage. Also recruits to sites of DNA damage proteins like XPA and XPG that are involved in nucleotide excision repair and is required for this mechanism of DNA repair. Plays also a role in base excision repair (BER) probably through interaction with UNG. Through RFWD3 may activate CHEK1 and play a role in replication checkpoint control. Also recruits SMARCAL1/HARP, which is involved in replication fork restart, to sites of DNA damage. May also play a role in telomere maintenance.
VE:
1 * 100 µl
Artikel-Nr:
(USBI044348)
Lieferant:
US Biological
Hersteller-Artikelnummer::
044348
Lokale Artikelnummer::
USBI044348
Beschreibung:
Anti-ZNF733P Rabbit Polyclonal Antibody
VE:
1 * 200 µl
Artikel-Nr:
(BOSSBS-3111R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3111R-HRP
Lokale Artikelnummer::
BOSSBS-3111R-HRP
Beschreibung:
Protein kinases are enzymes that transfer a phosphate group from a phosphate donor onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. The protein kinase family is one of the largest families of proteins in eukaryotes, classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. Epidermal Growth factor receptor (EGFR) is the prototype member of the type 1 receptor tyrosine kinases. EGFR overexpression in tumors indicates poor prognosis and is observed in tumors of the head and neck, brain, bladder, stomach, breast, lung, endometrium, cervix, vulva, ovary, esophagus, stomach and in squamous cell carcinoma.
VE:
1 * 100 µl
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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