Drucken
Sie suchten nach:
432 382 results were found
Antikörper
Artikel-Nr:
(USBI040990-FITC)
Lieferant:
US Biological
Hersteller-Artikelnummer::
040990-FITC
Lokale Artikelnummer::
USBI040990-FITC
Beschreibung:
Anti-RFXANK Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))
VE:
1 * 200 µl
Artikel-Nr:
(USBI039087-APC)
Lieferant:
US Biological
Hersteller-Artikelnummer::
039087-APC
Lokale Artikelnummer::
USBI039087-APC
Beschreibung:
Anti-NPFFR2 Rabbit Polyclonal Antibody (APC (Allophycocyanin))
VE:
1 * 200 µl
Lieferant:
Biotium
Beschreibung:
This antibody neutralises HurTNFamediated cytotoxicity of L929 cells and inhibits tumour growth in mice. It protects mice against toxicity of HurTNFa. Tumor Necrosis Factor Alpha (TNF alpha) is a protein secreted by lipopolysaccharide-stimulated macrophages, and causes tumor necrosis when injected into tumor bearing mice. TNF alpha is believed to mediate pathogenic shock and tissue injury associated with endotoxemia. TNF alpha exists as a multimer of two, three, or five non-covalently linked units, but shows a single 17 kDa band following SDS PAGE under non-reducing conditions. TNF alpha is closely related to the 25 kDa protein Tumor Necrosis Factor beta (lymphotoxin), sharing the same receptors and cellular actions. TNF alpha causes cytolysis of certain transformed cells, being synergistic with interferon gamma in its cytotoxicity. Although it has little effect on many cultured normal human cells, TNF alpha appears to be directly toxic to vascular endothelial cells. Other actions of TNF alpha include stimulating growth of human fibroblasts and other cell lines, activating polymorphonuclear neutrophils and osteoclasts, and induction of interleukin 1, prostaglandin E2 and collagenase production.
Artikel-Nr:
(BOSSBS-0485R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0485R-HRP
Lokale Artikelnummer::
BOSSBS-0485R-HRP
Beschreibung:
Receptor tyrosine kinase which binds promiscuously membrane-bound ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Activated by the ligand ephrin-A1/EFNA1 regulates migration, integrin-mediated adhesion, proliferation and differentiation of cells. Regulates cell adhesion and differentiation through DSG1/desmoglein-1 and inhibition of the ERK1/ERK2 (MAPK3/MAPK1, respectively) signaling pathway. May also participate in UV radiation-induced apoptosis and have a ligand-independent stimulatory effect on chemotactic cell migration. During development, may function in distinctive aspects of pattern formation and subsequently in development of several fetal tissues. Involved for instance in angiogenesis, in early hindbrain development and epithelial proliferation and branching morphogenesis during mammary gland development. Engaged by the ligand ephrin-A5/EFNA5 may regulate lens fiber cells shape and interactions and be important for lens transparency development and maintenance. With ephrin-A2/EFNA2 may play a role in bone remodeling through regulation of osteoclastogenesis and osteoblastogenesis.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1160R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1160R-A488
Lokale Artikelnummer::
BOSSBS-1160R-A488
Beschreibung:
Gelsolin is a calcium dependent actin binding protein. It is a potent modulator of actin filament length and gelation. Gelsolin has been shown to exist in at least two variant forms, cytoplasmic gelsolin and plasma gelsolin. Plasma gelsolin has also been called actin depolymerizing factor (ADF) or brevin. Human plasma and rabbit macrophage gelsolins differ by the presence of a 25 amino acid residue extension at the NH2 terminus in the human plasma gelsolin, which appears to account for the difference in relative molecular weights.
VE:
1 * 100 µl
Artikel-Nr:
(USBI128582)
Lieferant:
US Biological
Hersteller-Artikelnummer::
128582
Lokale Artikelnummer::
USBI128582
Beschreibung:
Anti-IRF2 Mouse Monoclonal Antibody [clone: 3B5]
VE:
1 * 100 µG
Artikel-Nr:
(BOSSBS-11403R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11403R-CY7
Lokale Artikelnummer::
BOSSBS-11403R-CY7
Beschreibung:
Gonadotropin-releasing hormone (GnRH) is released in a pulsatile manner that varies with the reproductive cycle. This hypothalamic hormone is transported to the pituitary, where it binds to specific receptors and regulates the synthesis and release of luteinizing hormone (LH) and follicle-stimulating hormone (FSH). Localized to the cell membrane, GnRHR2 mediates its own receptor activity via association with G proteins, thereby activating a phosphatidylinositol-calcium second messenger system that regulates GnRHR2 function. GnRHR2 is thought to have potent antiproliferative effects on ovarian and endometrial cancer cells, suggesting a possible role in tumor suppression. Due to alternative splicing events, GnRHR2 is expressed as two isoforms.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11665R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11665R-CY7
Lokale Artikelnummer::
BOSSBS-11665R-CY7
Beschreibung:
Clathrin-coated pits and vesicles are assembled for receptor-mediated endocytosis through interaction with clathrin associated protein complexes. Vesicle transport is mediated from the trans-Golgi network by the adapter complex AP-1 and from the plasma membrane by the AP-2 complex. The AP-1 and AP-2 adapter protein complexes consist of clathrin binding adaptin proteins and two smaller subunits known as AP50 and AP17. The Alpha- and Beta-Adaptin chains have a similar two-domain organization with C-terminal domains that vary in both sequence and length. Alpha-Adaptin splice variants A and C display variable relative expression levels and differential distribution in different tissues. AP180 (also designated AP-3 or F1-20) is a synapse-specific clathrin assembly protein. The protein CALM (clathrin assembly protein lymphoid myeloid leukemia) is highly homologous to AP180 and may also be involved in clathrin assembly.
VE:
1 * 100 µl
Lieferant:
Biotium
Beschreibung:
Recognizes a non-histone protein of 36 kDa, which is identified as proliferating cell nuclear antigen (PCNA). It is also known as cyclin or polymerase delta auxiliary protein. Elevated expression of PCNA/cyclin has been shown in the nucleus during late G1 phase immediately before the onset of DNA synthesis, becoming maximal during S-phase and declining during G2 and M phases. This MAb is excellent for multiple applications.
Artikel-Nr:
(BOSSBS-3156R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3156R-CY7
Lokale Artikelnummer::
BOSSBS-3156R-CY7
Beschreibung:
GCN2 belongs to a family of kinases that phosphorylate the alpha subunit of eukaryotic translation initiation factor 2 to downregulate protein synthesis in response to varied cellular stresses.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5020R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5020R-A647
Lokale Artikelnummer::
BOSSBS-5020R-A647
Beschreibung:
Plays a role in lipoprotein assembly and dietary cholesterol absorption. In addition to its acyltransferase activity, it may act as a ligase. May provide cholesteryl esters for lipoprotein secretion from hepatocytes and intestinal mucosa.
VE:
1 * 100 µl
Artikel-Nr:
(USBIP9104-91K)
Lieferant:
US Biological
Hersteller-Artikelnummer::
P9104-91K
Lokale Artikelnummer::
USBIP9104-91K
Beschreibung:
Anti-PDPN Sheep Polyclonal Antibody (Biotin)
VE:
1 * 50 µG
Artikel-Nr:
(USBI043669-BIOTIN)
Lieferant:
US Biological
Hersteller-Artikelnummer::
043669-BIOTIN
Lokale Artikelnummer::
USBI043669-BIOTIN
Beschreibung:
Anti-USP30 Rabbit Polyclonal Antibody (Biotin)
VE:
1 * 200 µl
Artikel-Nr:
(USBIS7049-88)
Lieferant:
US Biological
Hersteller-Artikelnummer::
S7049-88
Lokale Artikelnummer::
USBIS7049-88
Beschreibung:
Anti-SRY Mouse Monoclonal Antibody [clone: 9F639]
VE:
1 * 100 µG
Artikel-Nr:
(USBIP9003-01E-PE)
Lieferant:
US Biological
Hersteller-Artikelnummer::
P9003-01E-PE
Lokale Artikelnummer::
USBIP9003-01E-PE
Beschreibung:
Anti-PRKDC Rabbit Polyclonal Antibody (PE (Phycoerythrin))
VE:
1 * 200 µl
Artikel-Nr:
(BOSSBS-0015R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0015R-FITC
Lokale Artikelnummer::
BOSSBS-0015R-FITC
Beschreibung:
The insulin-like growth factors possess growth-promoting activity. In vitro, they are potent mitogens for cultured cells. IGF-II is influenced by placental lactogen and may play a role in fetal development. Preptin undergoes glucose-mediated co-secretion with insulin, and acts as physiological amplifier of glucose-mediated insulin secretion. Exhibits osteogenic properties by increasing osteoblast mitogenic activity through phosphoactivation of MAPK1 and MAPK3.
VE:
1 * 100 µl
Preis auf Anfrage
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Dieses Produkt kann nur an eine Lieferadresse versandt werden die über die entsprechende Lizenzen verfügt. Für weitere Hilfe bitte kontaktieren Sie Ihr VWR Vertriebszentrum.
-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
Dieses Produkt wurde von Ihrer Organisation gesperrt. Bitte kontaktieren Sie Ihren Einkauf für weitere Informationen.
Dieses Produkt ist Ersatz für den von Ihnen gewünschten Artikel.
Dieses Produkt ist nicht mehr verfügbar. Bitte kontaktieren Sie den VWR Kundenservice.
|
|||||||||
Listenansicht
