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Antikörper
Artikel-Nr:
(BOSSBS-3330R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3330R-FITC
Lokale Artikelnummer::
BOSSBS-3330R-FITC
Beschreibung:
Phosphorylates the alpha subunit of eukaryotic translation-initiation factor 2 (EIF2), leading to its inactivation and thus to a rapid reduction of translational initiation and repression of global protein synthesis. Serves as a critical effector of unfolded protein response (UPR)-induced G1 growth arrest due to the loss of cyclin-D1 (CCND1). Involved in control of mitochondrial morphology and function.
VE:
1 * 100 µl
Lieferant:
Biotium
Beschreibung:
The mouse monoclonal antibody recognizes CD1b, a 44 kDa type I glycoprotein associated with beta2-microglobulin. It is expressed on dendritic cells, Langerhans cells, thymocytes, and T acute lymphoblastic leukemia cells. The CD1 multigene family encodes five forms of the CD1 T-cell surface glycoprotein in human, designated CD1A, 1B, 1C, 1D and 1E. CD1, a type 1 membrane protein, has structural similarity to the MHC class I antigen and has been shown to present lipid antigens for recognition by T lymphocytes. Constitutive endocytosis of CD1B molecules and the differential sorting of MHC class II from lysosomes separate peptide- and lipid antigen-presenting molecules during dendritic cell maturation. CD1B is also expressed in interdigitating cells.
Artikel-Nr:
(BOSSBS-2362R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2362R-A647
Lokale Artikelnummer::
BOSSBS-2362R-A647
Beschreibung:
Recognizes the ribosomal RNA gene promoter and activates transcription mediated by RNA polymerase I through cooperative interactions with the transcription factor SL1/TIF-IB complex. It binds specifically to the upstream control element.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0385R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0385R-A647
Lokale Artikelnummer::
BOSSBS-0385R-A647
Beschreibung:
Required for consolidation of synaptic plasticity as well as formation of long-term memory. Regulates endocytosis of AMPA receptors in response to synaptic activity. Required for homeostatic synaptic scaling of AMPA receptors (By similarity). Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the stress fiber dynamics and cell migration.
VE:
1 * 100 µl
Lieferant:
Biotium
Beschreibung:
This antibody recognizes an oncofetal glycoprotein with a single chain of 70 kDa, which is identified as alpha fetoprotein (AFP) (ISOBM TD-2 workshop). This MAb is highly specific to AFP and shows no cross-reaction with other oncofetal antigens or serum albumin. AFP is normally synthesized in the liver, intestinal tract, and yolk sac of the fetus. Antibody to AFP has been shown to be useful in detecting hepatocellular carcinomas (HCC) and germ cell neoplasms, especially yolk sac tumors.
Artikel-Nr:
(BOSSBS-8284R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8284R-CY7
Lokale Artikelnummer::
BOSSBS-8284R-CY7
Beschreibung:
Collapsin response mediator proteins (CRMPs) are cytosolic phosphoproteins involved in neuronal differentiation and axonal guidance. CRMP2 was previously shown to mediate the repulsive effect of Sema3A on axons and to participate in axonal specification. The CRMPs appear to play a complex role in axon growth as well as microtubule dynamics and axon induction. CRMPs localize to the lamellipodia and filopodia of axonal growth cones, suggesting a role in axon guidance. Moreover, CRMP2 is upregulated after axotomy, and appears to increase the formation of axon-type processes from hippocampal neurons. CRMP2 has been reported to bind tubulin dimers directly and modulate microtubule assembly. CRMPs have also been implicated in the pathogenesis of a paraneoplastic neurologic syndrome. Interaction studies have implicated phospholipase D2 (PLD2), the cytosolic tyrosine kinase Fes, and intersectin in CRMP function. Hyperphosphorylation of CRMP2 is an early event in the progression of Alzheimer's disease.
VE:
1 * 100 µl
Artikel-Nr:
(USBI043073)
Lieferant:
US Biological
Hersteller-Artikelnummer::
043073
Lokale Artikelnummer::
USBI043073
Beschreibung:
Anti-TNFRSF13C Rabbit Polyclonal Antibody
VE:
1 * 200 µl
Artikel-Nr:
(USBI042748-HRP)
Lieferant:
US Biological
Hersteller-Artikelnummer::
042748-HRP
Lokale Artikelnummer::
USBI042748-HRP
Beschreibung:
Anti-TET2 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))
VE:
1 * 200 µl
Lieferant:
Biotium
Beschreibung:
This MAb recognizes a protein of 134 kDa, which binds fibroblast growth factor and E-selectin (cell-adhesion lectin on endothelial cells mediating the binding of neutrophils). Fucosylation is essential for binding to E-selectin. It contains sialic acid residues and 16 Cys-rich GLG1 repeats. This MAb can be used to stain the Golgi complex in cell or tissue preparations and can be used as a Golgi marker in subcellular fractions. It produces a diffuse staining pattern of the Golgi zone in normal and malignant cells. This MAb is an excellent marker for human cells in xenographic model research. It reacts specifically with human cells. The Golgi apparatus is an organelle present in all eukaryotic cells that forms a part of the endomembrane system. The primary function of the Golgi apparatus is to process and package macromolecules synthesized by the cell for exocytosis or use within the cell. The Golgi is made up of a stack of flattened, membrane-bound sacs known as cisternae, with three functional regions: the cis face, medial region and trans face. Each region consists of various enzymes that selectively modify the macromolecules passing though them, depending on where they are destined to reside. Several spherical vesicles that have budded off of the Golgi are present surrounding the main cisternae. The Golgi tends to be more pronounced and numerous in cells that make and secrete many substances such as plasma B cells.
Artikel-Nr:
(IMMRIR1365)
Lieferant:
ImmunoReagents
Hersteller-Artikelnummer::
IR1365
Lokale Artikelnummer::
IMMRIR1365
Beschreibung:
ImmunoReagents is a manufacturer of quality research and production reagents for the Life Science Industries. Product lines include a wide range of antibodies used in ELISA, immunohistochemistry (IHC), western blotting, flow cytometry (FACS), immunofluorescence and microscopy. Antibodies produced cover a broad range of Immunoglobulins from various species cross absorbed to provide high specificity.
VE:
1 * 1 mg
Lieferant:
Biotium
Beschreibung:
This antibody recognizes a protein of 66 kDa-170 kDa, identified as involucrin. In Western blotting of cultured human keratinocytes, this MAb reacts with a 120 kDa protein. It stains the involucrin in a variety of sizes: 170 kDa in MCF-7 cells, a doublet of ~115 kDa and 150 kDa in gorilla and owl monkey, 66 kDa in dog, and a doublet of 105 kDa in pig. Its epitope maps between codon 421-568 of human involucrin. Involucrin is expressed in a range of stratified squamous epithelia, including the cornea, which lacks a distinct cornified layer. In normal epidermis, it is first expressed in the upper spinous layers, and in keratinocyte cultures, all cells that have left the basal layer express it. Involucrin expression is altered in pathological conditions: in psoriasis and other benign epidermal hyperplasias, involucrin expression begins closer to the basal layer than normal; expression is abnormal in squamous cell carcinomas and premalignant lesions, and is reduced in severe dysplasias of the larynx and cervix.
Lieferant:
Biotium
Beschreibung:
Recognizes a protein of 180 kDa, identified as CD11a (Leucocyte Workshop IV; Code 1524). CD11a complex with the 2 subunit of the integrin family, CD18, to form the cell surface heterodimer, LFA-1 or CD11a /C18 (aLbL). LFA-1 is expressed on all leukocytes including lymphocytes, monocytes, and granulocytes. It is involved in leukocyte adhesion to its ligands including intercellular adhesion molecule-1 (ICAM-1 or CD54), ICAM-2 (CD102), ICAM-3 (CD50) and Telencephalin (TLN) and play a role in most immune/inflammatory responses. This MAb potently blocks LFA-1 dependent homotypic cell aggregation.
Artikel-Nr:
(USBI033225)
Lieferant:
US Biological
Hersteller-Artikelnummer::
033225
Lokale Artikelnummer::
USBI033225
Beschreibung:
Anti-CATSPER1 Rabbit Polyclonal Antibody
VE:
1 * 200 µl
Artikel-Nr:
(USBI033852-APC)
Lieferant:
US Biological
Hersteller-Artikelnummer::
033852-APC
Lokale Artikelnummer::
USBI033852-APC
Beschreibung:
Anti-CHMP2B Rabbit Polyclonal Antibody (APC (Allophycocyanin))
VE:
1 * 200 µl
Artikel-Nr:
(USBI038896-FITC)
Lieferant:
US Biological
Hersteller-Artikelnummer::
038896-FITC
Lokale Artikelnummer::
USBI038896-FITC
Beschreibung:
Anti-NPHS1 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))
VE:
1 * 200 µl
Artikel-Nr:
(USBIS1014-08E6A)
Lieferant:
US Biological
Hersteller-Artikelnummer::
S1014-08E6A
Lokale Artikelnummer::
USBIS1014-08E6A
Beschreibung:
Anti-Six3b Goat Polyclonal Antibody
VE:
1 * 100 µG
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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