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Antikörper
Artikel-Nr:
(USBIG4000-05A)
Lieferant:
US Biological
Hersteller-Artikelnummer::
G4000-05A
Lokale Artikelnummer::
USBIG4000-05A
Beschreibung:
Anti-GAD1 Goat polyclonal antibody
VE:
1 * 100 µG
Artikel-Nr:
(BOSSBS-9379R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9379R-FITC
Lokale Artikelnummer::
BOSSBS-9379R-FITC
Beschreibung:
The Makorins are a family of putative ribonucleoproteins containing two to four C3H zinc fingers that may confer RNA-binding. In addition, they contain a C3HC4 RING zinc finger that allows them to function as E3 ubiquitin ligases. Makorin-2, also known as RNF62, HSPC070 or MKRN2, is a widely expressed, evolutionarily conserved protein with four C3H-type zinc fingers (three at the N-terminus and one at the C-terminus), one RING-type zinc finger and a cysteine and histidine motif similar to that found in Makorin-1. In Xenopus, Makorin-2 functions, via PI 3-kinase/Akt signaling, as a negative regulator of neurogenesis. In humans, Makorin-2 is overexpressed in various cancer cell lines, suggesting a possible role of Makorin-2 in tumor progression. In addition, Makorin-2 is co-expressed with Raf-1 in the same tissues and cell lines.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11439R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11439R-CY5
Lokale Artikelnummer::
BOSSBS-11439R-CY5
Beschreibung:
May act as a redox regulator involved in DUOX proteins folding. The interaction with DUOX1 and DUOX2 suggest that it belongs to a multiprotein complex constituting the thyroid H(2)O(2) generating system. It is however not sufficient to assist DUOX1 and DUOX2 in H(2)O(2) generation.
VE:
1 * 100 µl
Artikel-Nr:
(PRSI36-031)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
36-031
Lokale Artikelnummer::
PRSI36-031
Beschreibung:
ACE2 has direct effects on cardiac functions. It is expressed predominantly in vascular endothelial cells of the heart and kidney. ACE2 converts angiotensin I to angiotensin 1-9. ACE2 was also identified as a functional receptor for SARS coronavirus.
VE:
1 * 100 µG
Artikel-Nr:
(BOSSBS-8211R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8211R-FITC
Lokale Artikelnummer::
BOSSBS-8211R-FITC
Beschreibung:
FAM84B, also known as NSE2 or BCMP101, is a 310 amino acid protein that is expressed in esophageal squamous cell carcinomas, suggesting a role in tumor development and metastasis. The gene encoding FAM84B maps to human chromosome 8, which consists of nearly 146 million base pairs, houses more than 800 genes and is associated with a variety of diseases and malignancies. Schizophrenia, bipolar disorder, trisomy 8, Pfeiffer syndrome, congenital hypothyroidism, Waardenburg syndrome and some leukemias and lymphomas are thought to occur as a result of defects in specific genes that map to chromosome 8.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9120R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9120R-A555
Lokale Artikelnummer::
BOSSBS-9120R-A555
Beschreibung:
Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, c-jun/JUN, IkappaBalpha/NFKBIA, ITPK1 and IRF8, possibly via its association with CK2 and PKD kinases. CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively. Has some glucocorticoid receptor-responsive activity.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9345R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9345R-A488
Lokale Artikelnummer::
BOSSBS-9345R-A488
Beschreibung:
E3 ubiquitin-protein ligase that mediates polyubiquitination of CD4. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates. May play a role in ubuquitin-dependent protein sorting in developmenting spermatids.
VE:
1 * 100 µl
Lieferant:
Biotium
Beschreibung:
The onset of angiogenesis is believed to be an early event in tumorigenesis and may facilitate tumor progression and metastasis. Several growth factors with angiogenic activity have been described. These include Fibroblast Growth Factor (FGF), Platelet Derived Growth Factor (PDGF), Vascular Endothelial Growth Factor (VEGF) and Placenta Growth Factor (PLGF). Placenta growth factor (PLGF) is a secreted protein primarily produced by placental trophoblasts but also expressed in other endothelial cells and tumors. There are three isoforms, PLGF-1, PLGF-2, and PLGF-3. PLGF-2 is expressed up until week 8 in the placenta; the placental tissues continuously express PLGF-1 and PLGF-3 but only PLGF-1 is found in colon and mammary carcinomas. PLGF acts to stimulate angiogenesis, endothelial growth and migration. PLGF is a powerful promoter of tumor growth and is upregulated in some cancers, and PLGF is thought to aid in atherosclerotic lesions and neovascular growth surrounding the lesion. Also, PLGF appears to aid aldosterone mediated atherosclerosis. Serum levels of PLGF in some cases are used as a potential biomarker for disease or genetic defect. Recent research indicates that PLGF levels are lower in mothers with Down syndrome fetuses. Evidence has suggested VEGF to be an obligatory component in PLGF signaling. While VEGF homodimers and VEGF/PLGF heterodimers function as potent mediators of mitogenic and chemotactic responses in endothelial cells, PLGF homodimers are effectual only at extremely high concentrations. Indeed, many of the physiological effects attributed to VEGF may actually be a result of VEGF/PLGF. VEGF and PLGF share a common receptor, Flt-1, and may also activate Flk-1/KDR.
Artikel-Nr:
(BOSSBS-1258R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1258R-CY5.5
Lokale Artikelnummer::
BOSSBS-1258R-CY5.5
Beschreibung:
ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). ICAM2 may play a role in lymphocyte recirculation by blocking LFA-1-dependent cell adhesion. It mediates adhesive interactions important for antigen-specific immune response, NK-cell mediated clearance, lymphocyte recirculation, and other cellular interactions important for immune response and surveillance.
VE:
1 * 100 µl
Artikel-Nr:
(USBIA1475-03C-PE)
Lieferant:
US Biological
Hersteller-Artikelnummer::
A1475-03C-PE
Lokale Artikelnummer::
USBIA1475-03C-PE
Beschreibung:
Anti-PRKAB1 Rabbit Polyclonal Antibody (PE (Phycoerythrin))
VE:
1 * 200 µl
Artikel-Nr:
(USBI044092-FITC)
Lieferant:
US Biological
Hersteller-Artikelnummer::
044092-FITC
Lokale Artikelnummer::
USBI044092-FITC
Beschreibung:
Anti-ZMAT2 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))
VE:
1 * 200 µl
Artikel-Nr:
(ROCK606-1004)
Lieferant:
Rockland Immunochemicals
Hersteller-Artikelnummer::
606-1004
Lokale Artikelnummer::
ROCK606-1004
Beschreibung:
Secondary Goat Anti-IgG F(ab')2 Reacts with Guinea Pig
VE:
1 * 2 mg
Artikel-Nr:
(BOSSBS-3248R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3248R-CY5.5
Lokale Artikelnummer::
BOSSBS-3248R-CY5.5
Beschreibung:
This gene, which encodes a member of the serine/threonine kinase family, regulates cell polarity and functions as a tumor suppressor. Mutations in this gene have been associated with Peutz-Jeghers syndrome, an autosomal dominant disorder characterized by the growth of polyps in the gastrointestinal tract, pigmented macules on the skin and mouth, and other neoplasms. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. [provided by RefSeq, Jul 2008].
VE:
1 * 100 µl
Artikel-Nr:
(USBI150114)
Lieferant:
US Biological
Hersteller-Artikelnummer::
150114
Lokale Artikelnummer::
USBI150114
Beschreibung:
Anti-RAN Goat Polyclonal Antibody
VE:
1 * 100 µG
Artikel-Nr:
(USBIC9097-21D)
Lieferant:
US Biological
Hersteller-Artikelnummer::
C9097-21D
Lokale Artikelnummer::
USBIC9097-21D
Beschreibung:
Anti-KRT18 Mouse Monoclonal Antibody [clone: 5F228]
VE:
1 * 50 µG
Lieferant:
Biotium
Beschreibung:
Recognizes a 47-55 kDa-tumor suppressor protein, identified as Wilm's Tumor (WT1) protein. The antibody reacts with all isoforms of the full-length WT1 and also identifies WT1 lacking exon 2-encoded amino acids, frequently found in subsets of sporadic Wilm s tumors.WT1, a sporadic and familial pediatric kidney tumor, is genetically heterogeneous. Wilm s tumor is associated with mutations of WT1, a zinc-finger transcription factor that is essential for the development of the metanephric kidney and the urogenital system. The WT1 gene is normally expressed in fetal kidney and mesothelium, and its expression has been suggested as a marker for Wilm s tumor and mesothelioma. WT1 protein has been identified in proliferative mesothelial cells, malignant mesothelioma, ovarian carcinoma, gonadoblastoma, nephroblastoma, and desmoplastic small round cell tumor. Lung adenocarcinomas rarely stain positive with this antibody. WT1 protein expression in mesothelial cells has become a reliable marker for the diagnosis of mesotheliomas.
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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