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Antikörper
Lieferant:
Biotium
Beschreibung:
Recognizes a protein of 110 kDa, identified as CD106 (also known as vascular cell adhesion molecule-1 (VCAM-1) and INCAM-100). CD106 is a member of the Ig superfamily of adhesion molecules and is expressed at high levels on cytokine stimulated vascular endothelial cells, and at minimal levels on un-stimulated endothelial cells. It is also present on follicular and inter-follicular dendritic cells of lymph nodes, myoblasts, and some macrophages. CD106 serves as a ligand for leukocyte integrin (VLA-4 or CD49d/CD29) and mediates cell adhesion of leukocytes to activated endothelium. It plays a role in various immunological and inflammatory responses. This MAb inhibits the binding of leukocytes to VCAM-1 on stimulated endothelial cells.
Artikel-Nr:
(ABGEAP18657C)
Lieferant:
Abgent
Hersteller-Artikelnummer::
AP18657C
Lokale Artikelnummer::
ABGEAP18657C
Beschreibung:
Anti-APOBR Rabbit Polyclonal Antibody
VE:
1 * 400 µl
Artikel-Nr:
(BOSSBS-5141R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5141R-CY3
Lokale Artikelnummer::
BOSSBS-5141R-CY3
Beschreibung:
Matrin 3 (MATR 3) is an internal nuclear matrix protein that may play a role in transcription or may interact with other nuclear matrix proteins to form the internal fibrogranular network. In association with the SFPQ-NONO heteromer MATR 3 may play a role in nuclear retention of defective RNAs. MATR3 forms part of complex consisting of SFPQ, NONO and MATR3.The protein contains 1 matrin type zinc finger and 2 RRM (RNA recognition motif) domains. Two transcript variants encoding the same protein have been identified for this gene.
VE:
1 * 100 µl
Artikel-Nr:
(USBI043315-AP)
Lieferant:
US Biological
Hersteller-Artikelnummer::
043315-AP
Lokale Artikelnummer::
USBI043315-AP
Beschreibung:
Anti-TSC1 Rabbit Polyclonal Antibody (AP (Alkaline Phosphatase))
VE:
1 * 200 µl
Artikel-Nr:
(USBIB2702-01K)
Lieferant:
US Biological
Hersteller-Artikelnummer::
B2702-01K
Lokale Artikelnummer::
USBIB2702-01K
Beschreibung:
Anti-Brain Natriuretic Peptide, Pro Mouse Monoclonal Antibody [clone: 7E102]
VE:
1 * 1 mg
Artikel-Nr:
(BOSSBS-10425R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-10425R-A750
Lokale Artikelnummer::
BOSSBS-10425R-A750
Beschreibung:
Regulator of cell surface receptor signal transduction. Plays a central role in retinal vascularization by regulating norrin (NDP) signal transduction. Acts in concert with norrin (NDP) to promote FZD4 multimerization and subsequent activation of FZD4, leading to promote accumulation of beta-catenin (CTNNB1) and stimulate LEF/TCF-mediated transcriptional programs. Surprisingly, it only activate the norrin (NDP)-dependent activation of FZD4, while it does not activate the Wnt-dependent activation of FZD4, suggesting the existence of a Wnt-independent Signalling that also promote accumulation the beta-catenin (CTNNB1) (By similarity). Acts as a regulator of membrane proteinases such as ADAM10 and MMP14/MT1-MMP. Activates ADAM10-dependent cleavage activity of amyloid precursor protein (APP). Activates MMP14/MT1-MMP-dependent cleavage activity.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5636R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5636R-A680
Lokale Artikelnummer::
BOSSBS-5636R-A680
Beschreibung:
Synaptotagmins (Syts) are a large gene family of synaptic vesicle integral membrane proteins. Syt functions as regulators of both exocytosis /endocytosis and is involved in neurotransmitter secretion from small secretory vesicles. 13 isoforms of Syt have been identified(SytI-XIII). SynaptotagminVI is localised to the endoplasmic reticulum and/or Golgi like perinuclear compartment. It may be important for trafficking and calcium signaling as it is specially expressed in nonneuronal tissues. Also SytVI is present in the acrosomal region of mammalian spermatozoa. The cytosolic domain of SytVI can abrogate exocytosis by competing with the endogenous protein for essential interactions with the fusion machinery involved in a acrosomal exocytosis.
VE:
1 * 100 µl
Artikel-Nr:
(USBI041046-HRP)
Lieferant:
US Biological
Hersteller-Artikelnummer::
041046-HRP
Lokale Artikelnummer::
USBI041046-HRP
Beschreibung:
Anti-RIC3 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))
VE:
1 * 200 µl
Artikel-Nr:
(BOSSBS-8356R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8356R-CY7
Lokale Artikelnummer::
BOSSBS-8356R-CY7
Beschreibung:
Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-48'-linked polyubiquitination. Mediates the selective degradation of short-lived and abnormal proteins. Functions in the E6/E6-AP-induced ubiquitination of p53/TP53. Mediates ubiquitination of PEX5 and auto-ubiquitination of CHIP, TRAF6 and TRIM63/MURF1. Ubiquitinates CHIP-associated HSP90AB1 in vitro. Lacks inherent specificity for any particular lysine residue of ubiquitin. Essential for viral activation of IRF3. Mediates polyubiquitination of CYP3A4.
VE:
1 * 100 µl
Artikel-Nr:
(USBI043178-BIOTIN)
Lieferant:
US Biological
Hersteller-Artikelnummer::
043178-BIOTIN
Lokale Artikelnummer::
USBI043178-BIOTIN
Beschreibung:
Anti-TRADD Rabbit Polyclonal Antibody (Biotin)
VE:
1 * 200 µl
Artikel-Nr:
(BOSSBS-3899R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3899R-A647
Lokale Artikelnummer::
BOSSBS-3899R-A647
Beschreibung:
Has a role in maintaining calcium homeostasis. Catalyzes the NADPH-dependent 24-hydroxylation of calcidiol (25-hydroxyvitamin D(3)) and calcitriol (1-alpha,25-dihydroxyvitamin D(3)). The enzyme can perform up to 6 rounds of hydroxylation of calcitriol leading to calcitroic acid. It also shows 23-hydroxylating activity leading to 1-alpha,25-dihydroxyvitamin D(3)-26,23-lactone as end product.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8269R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8269R-FITC
Lokale Artikelnummer::
BOSSBS-8269R-FITC
Beschreibung:
GIMAP3p is a murine mitochondrial membrane protein belonging to the GTP-binding superfamily and to the immuno-associated nucleotide (IAN) subfamily of nucleotide-binding proteins. The IAN/GIMAP family consists of GTP-binding proteins that share a unique primary structure and whose expression is finely regulated by T-cell receptor signals. Recent studies have shown that IAN/GIMAP family proteins crucially regulate the survival of T cells during development, selection and homeostasis, and are possibly linked to the onset of T-lymphopenia, leukemia and autoimmunity. IAN/GIMAP family proteins might also take part in mitochondrial regulation of lymphocyte apoptosis by interacting with Bcl-2 family proteins. The human GIMAP (GTPase of the immunity-associated protein) gene family includes seven functional members residing on (human) chromosome 7q36.1 and one pseudogene (hGIMAP3).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5707R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5707R-A488
Lokale Artikelnummer::
BOSSBS-5707R-A488
Beschreibung:
TUSC2/FUS1 is a novel tumor suppressor gene identified in the human chromosome 3p21.3 region where allele losses and genetic alterations occur early and frequently for many human cancers. Expression of TUSC2 protein is absent or reduced in the majority of lung cancers and premalignant lung lesions. Restoration of TUSC2 function in 3p21.3-deficient non-small cell lung carcinoma cells significantly inhibits tumor cell growth by induction of apoptosis and alteration of cell cycle kinetics. TUSC2 may induce apoptosis through the activation of the intrinsic mitochondrial-dependent and Apaf-1-associated pathways and inhibit the function of protein tyrosine kinases including EGFR, PDGFR, AKT, c-Abl, and c-Kit.
VE:
1 * 100 µl
Artikel-Nr:
(USBI034607-AP)
Lieferant:
US Biological
Hersteller-Artikelnummer::
034607-AP
Lokale Artikelnummer::
USBI034607-AP
Beschreibung:
Anti-DHCR7 Rabbit Polyclonal Antibody (AP (Alkaline Phosphatase))
VE:
1 * 200 µl
Artikel-Nr:
(USBI043688-HRP)
Lieferant:
US Biological
Hersteller-Artikelnummer::
043688-HRP
Lokale Artikelnummer::
USBI043688-HRP
Beschreibung:
Anti-UTP3 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))
VE:
1 * 200 µl
Artikel-Nr:
(USBIP9103-42L)
Lieferant:
US Biological
Hersteller-Artikelnummer::
P9103-42L
Lokale Artikelnummer::
USBIP9103-42L
Beschreibung:
Anti-PRKCQ Rabbit Polyclonal Antibody
VE:
1 * 100 µl
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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