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Proteine und Peptide
Artikel-Nr:
(PRSI91-425)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
91-425
Lokale Artikelnummer::
PRSI91-425
Beschreibung:
Rat Macrophage colony-stimulating factor 1(MCSF,CSF1) is a single-pass type I membrane cytokine. It is a hematopoietic growth factor that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. MCSF promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. It is involved in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development which for normal male and female fertility. It promotes reorganization of the actin cytoskeleton, regulates formation of membrane ruffles, cell adhesion and cell migration. MCSF also plays a role in lipoprotein clearance.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI92-338)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
92-338
Lokale Artikelnummer::
PRSI92-338
Beschreibung:
Neuronal acetylcholine receptor subunit beta-3(CHRNB3) is a cell membrane protein and belongs to the ligand-gated ion channel (TC 1.A.9) family. CHRNB3 seems to be composed of two different type of subunits: alpha and beta. The CHRNB3 are (hetero) pentamers composed of homologous subunits. The subunits that make up the muscle and neuronal forms of CHRNB3 are encoded by separate genes and have different primary structure. There are several subtypes of neuronal CHRNB3 that vary based on which homologous subunits are arranged around the central channel. They are classified as alpha-subunits if like muscle alpha-1, they have a pair of adjacent cysteines as part of the presumed acetylcholine binding site. Subunits lacking these cysteine residues are classified as beta-subunits.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI90-316)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
90-316
Lokale Artikelnummer::
PRSI90-316
Beschreibung:
Irisin is a recently described exercise-induced hormone secreted by skeletal muscle in mice and humans. Irisin activates beige fat cells (beige cells have a gene expression pattern distinct from either white or brown fat and are preferentially sensitive to the polypeptide hormone Irisin). Irisin is cleaved from the type I membrane protein FNDC5 and improves systemic metabolism by increasing energy expenditure.
VE:
1 * 10 µG
Artikel-Nr:
(PRSI5071P)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
5071P
Lokale Artikelnummer::
PRSI5071P
Beschreibung:
PCDH12 peptide is used for blocking the activity of PCDH12 antibody.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI7001P)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
7001P
Lokale Artikelnummer::
PRSI7001P
Beschreibung:
RGS22 peptide is used for blocking the activity of RGS22 antibody.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI96-745)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
96-745
Lokale Artikelnummer::
PRSI96-745
Beschreibung:
Tumor necrosis factor receptor superfamily member 10A (TNFRSF10A) is also known as TNF-related apoptosis-inducing ligand receptor 1 (TRAIL-R1), Death receptor 4 (DR4), CD261 and APO2, which belongs to TNF superfamily. TRAILR1 / TNFRSF10A contains 1 death domain and 3 TNFR-Cys repeats. TNFRSF10A / DR4 is widely expressed and high levels are found in spleen, peripheral blood leukocytes, small intestine and thymus, but also in K-562 erythroleukemia cells, MCF-7 breast carcinoma cells and activated T-cells. APO2 / TNFRSF10A is receptor for the cytotoxic ligand TNFSF10 / TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI6057P)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
6057P
Lokale Artikelnummer::
PRSI6057P
Beschreibung:
SHISA9 peptide is used for blocking the activity of SHISA9 antibody.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI92-106)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
92-106
Lokale Artikelnummer::
PRSI92-106
Beschreibung:
Estrogen Receptor Beta (ESR2) is a nuclear protein that belongs to the nuclear hormone receptor family of NR3 subfamily. It contains one nuclear receptor DNA-binding domain and is expressed in many tissues at a lower level. ESR2 is a nuclear hormone receptor. It binds estrogens with an affinity similar to that of ESR1 and activates expression of reporter genes containing estrogen response elements (ERE) in an estrogen-dependent manner. DNA-binding by ESR1 and ESR2 is rapidly lost at 37 degrees Celsius in the absence of ligand while in the presence of 17 beta-estradiol and 4-hydroxy-tamoxifen loss in DNA-binding at elevated temperature is more gradual.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI92-271)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
92-271
Lokale Artikelnummer::
PRSI92-271
Beschreibung:
Polyubiquitin-B(UBB) is one of Ubiquitins. Ubiquitin is one of the most conserved proteins known in eukaryotic organisms. Ubiquitin is required for ATP-dependent, non-lysosomal intracellular protein degradation of abnormal proteins and normal proteins with a rapid turnover. Ubiquitin is covalently bound to proteins to be degraded, and presumably labels these proteins for degradation.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI7305P)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
7305P
Lokale Artikelnummer::
PRSI7305P
Beschreibung:
16 amino acids near the amino terminus of human TIAF.
VE:
1 * 50 µG
Lieferant:
Shenandoah Biotechnology
Beschreibung:
Vascular endothelial growth factor-A (VEGF-A) is produced by a wide variety of cell types, including tumor and vascular cells. VEGF-A is a mediator of vascular growth, vascular permeability, and plays a role in stimulating vasodilation via nitric oxide-dependent pathways. VEGF-A has several alternatively spliced isoforms, with one being VEGF-121. The VEGF-121 isoform is a secreted protein that acts on receptors VEGFR-1 and VEGFR-2 to modulate endothelial cell function.
Artikel-Nr:
(PRSI6299P)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
6299P
Lokale Artikelnummer::
PRSI6299P
Beschreibung:
SIK1 peptide is used for blocking the activity of SIK1 antibody.
VE:
1 * 50 µG
Artikel-Nr:
(734-0099)
Lieferant:
Corning
Hersteller-Artikelnummer::
354233
Lokale Artikelnummer::
BDAA354233
Beschreibung:
Collagen IV ist eine in der Basalmembran ubiquitär vorhandene, schichtartige Matrix, die Epithel- und Endothelzellen unterliegt und Muskelfett- und Nervenzellen umgibt. Es kann auch als dünne Schicht auf Gewebekulturoberflächen aufgetragen werden, um die Zellanhaftung zu verbessern und die Wirkung von Collagen IV auf das Zellverhalten zu erforschen.
VE:
1 * 1 mg
Artikel-Nr:
(PRSI91-068)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
91-068
Lokale Artikelnummer::
PRSI91-068
Beschreibung:
Tumor necrosis factor alpha (TNF alpha) is the prototypic ligand of the TNF superfamily. TNF alpha forms a homotrimer and functions by activating two types of receptors TNF-R1 (TNF receptor type 1,p55R) and TNF-R2 (TNF receptor type 2,p75R). TNF alpha is a pleiotropic cytokine that is capable to promote inflammation, to induce apoptotic cell death, and to inhibit tumorigenesis and viral replication. TNF alpha is a potent lymphoid factor that exerts cytotoxic effects on a wide range of tumor cells and certain other target cells.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI40-537)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
40-537
Lokale Artikelnummer::
PRSI40-537
Beschreibung:
TPO is a lineage specific growth factor, produced in the liver, kidney and skeletal muscle. It stimulates the proliferation and maturation of megakaryocytes, and promotes increased circulating levels of platelets in vivo. TPO signals through the c-mpl receptor and acts as an important regulator of circulating platelets. Human and murine TPO exhibits cross-species reactivity. Recombinant rat TPO is a fully biologically active 174 amino acid polypeptide (18.7 kDa), which contains the erythropoietin-like domain of the full length TPO protein.
VE:
1 * 10 µG
Artikel-Nr:
(PRSI92-428)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
92-428
Lokale Artikelnummer::
PRSI92-428
Beschreibung:
Kell blood group glycoprotein (KEL) is a single-pass type II membrane protein which belongs to the peptidase M13 family. It is expressed in Expressed at high levels in erythrocytes and testis, and, at lower levels, in skeletal muscle, tonsils, lymph node, spleen and appendix. KEL has been shown zinc endopeptidase with endothelin-3-converting enzyme activity. It cleaves EDN1, EDN2 and EDN3, with a marked preference for EDN3. It links via a single disulfide bond to the XK membrane protein that carries the Kx antigen.
VE:
1 * 50 µG
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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