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Proteine und Peptide
Artikel-Nr:
(PRSI91-249)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
91-249
Lokale Artikelnummer::
PRSI91-249
Beschreibung:
Gamma-Aminobutyric Acid Receptor-Associated Protein-Like 1 (GABARAPL1) is a cytoplasmic protein that belongs to the MAP1 LC3 family. GABARAPL1 is expressed at very high levels in the brain, heart, peripheral blood leukocytes, liver, kidney, placenta, and skeletal muscle. It can interact with GABRG2, OPRK1 and beta -Tubulin. GABARAPL1 increases cell-surface expression of kappa-type opioid receptor through facilitating anterograde intracellular trafficking of the receptor.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI91-167)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
91-167
Lokale Artikelnummer::
PRSI91-167
Beschreibung:
Ubiquitin-Conjugating Enzyme E2 T (UBE2T) is a ligase that belongs to the Ubiquitin-Conjugating Enzyme family. UBE2T accepts the ATP-dependent ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro, UBE2T is able to catalyze polyubiquitination using all 7 ubiquitin Lys residues, but may prefer 'Lys-11'-, 'Lys-27'-, 'Lys-48'- and 'Lys-63'-linked polyubiquitination. UBE2T is an important factor of the Faconi anemia pathway of DNA damage repair and, upon self-inactivation, may negatively regulate the Faconi pathway.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI91-036)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
91-036
Lokale Artikelnummer::
PRSI91-036
Beschreibung:
FGF-basic is a members of the Fibroblast Growth Factors (FGFs) family.The family constitutes a large family of proteins involved in many aspects of development including cell proliferation, growth, and differentiation. They act on several cell types to regulate diverse physiologic functions including angiogenesis, cell growth, pattern formation, embryonic development, metabolic regulation, cell migration, neurotrophic effects, and tissue repair. FGF-basic is a non-glycosylated heparin binding growth factor that is expressed in the brain, pituitary, kidney, retina, bone, testis, adrenal gland liver, monocytes, epithelial cells and endothelial cells. FGF-basic signals through FGFR 1b, 1c, 2c, 3c and 4.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI2395P)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
2395P
Lokale Artikelnummer::
PRSI2395P
Beschreibung:
TACI peptide is used for blocking the activity of TACI antibody.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI96-592)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
96-592
Lokale Artikelnummer::
PRSI96-592
Beschreibung:
Programmed cell death 1 ligand 1 (PDL1) is also known as B7-H, B7H1, MGC142294, MGC142296, PD-L1, PDCD1L1 and PDCD1LG1,which is a member of the growing B7 family of immune molecules and is involved in the regulation of cellular and humoral immune responses.PDL1 is a cell surface immunoglobulin superfamily with two Ig-like domains within the extracellular region and a short cytoplasmic domain. This protein is broadly expressed in the majority of peripheral tissues as well as hematopoietic cells. Interaction between PDL1 and its receptors belonging to the CD28 family of molecules provide both stimulatory and inhibitory signals in regulating T cell activation and tolerance. PDL1 may inhibit ongoing T-cell responses by inducing apoptosis and arresting cell-cycle progression.
VE:
1 * 100 µG
Lieferant:
Shenandoah Biotechnology
Beschreibung:
Interleukin 3 (IL-3) is a cytokine that is produced by activated T cells and mast cells. IL-3 induces the differentiation of hematopoietic stem cells into myeloid precursor cells, such as erythrocyte, megakaryocyte, granulocyte, monocyte, and dendritic cells. IL-3 also functions in the nervous system and is important during the B-1 cell regulation of chronic inflammatory diseases.
Artikel-Nr:
(PRSI90-055)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
90-055
Lokale Artikelnummer::
PRSI90-055
Beschreibung:
ANGPTL7 (Angiopoietin-like protein 7) is expressed in various tissues and regulates angiogenesis. Human ANGPTL7 was characterised as a potent target gene of the WNT/beta-catenin signalling pathway, and is a pharmacogenomics target in the fields of oncology and regenerative medicine. Overexpression of ANGPTL7 increases collagen expression and might exert a pathogenic role in glaucoma.
VE:
1 * 10 µG
Artikel-Nr:
(PRSI4677P)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
4677P
Lokale Artikelnummer::
PRSI4677P
Beschreibung:
BICD2 peptide is used for blocking the activity of BICD2 antibody.
VE:
1 * 50 µG
Lieferant:
Shenandoah Biotechnology
Beschreibung:
Interleukin 8 (IL-8 oder CXCL8) ist ein Mitglied der CXC-Zytokinfamilie und wird von Makrophagen, Epithelzellen, glatten Muskelzellen und Endothelzellen produziert. IL-8 bindet die G-Protein-gekoppelten Serpentinrezeptoren CXCR1 und CXCR2. IL-8 rekrutiert angeborene Immunzellen, induziert die Phagozytose und stimuliert die Angiogenese.
Artikel-Nr:
(PRSI96-750)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
96-750
Lokale Artikelnummer::
PRSI96-750
Beschreibung:
Tumor necrosis factor receptor superfamily member 10B (TNFRSF10B) is also known as TNF-related apoptosis-inducing ligand receptor 2 (TRAILR2), Death receptor 5 (DR5), CD262, KILLER, is a member of the TNF-receptor superfamily, and contains an intracellular death domain. TNFRSF10B / DR-5 is widely expressed in adult and fetal tissues; very highly expressed in tumor cell lines. TRAILR2 / CD262 / DR5 is the receptor for the cytotoxic ligand TNFSF10/TRAIL. The adapter molecule FADD (a death domain containing adaptor protein) of TRAIL-R2 / TNFRSF10B recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. CD262 / DR5 Promotes the activation of NF-kappa-B. DR5 is essential for ER stress-induced apoptosis and is regulated by p53/TP53.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI96-551)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
96-551
Lokale Artikelnummer::
PRSI96-551
Beschreibung:
Natural cytotoxicity triggering receptor 3 (NCR3) is also known as Activating natural killer receptor p30, Natural killer cell p30-related protein (NK-p30), CD antigen CD337, 1C7, LY117. NCR3 /CD337 /NKp30 belongs to the natural cytotoxicity receptor (NCR) family. NCR3 /NKp30 contains one Ig-like (immunoglobulin-like) domain. NCR3 /NKp30 is selectively expressed by all resting and activated NK cells and weakly expressed in spleen. NCR3 is homodimer in the unliganted form. NCR3 interacts with CD3Z. NCR3 interacts with and is activated by binding to NCR3LG1 or BAG6. Engagement of NCR3 by BAG6 also promotes dendritic cell (DC) maturation, both through killing those DCs that did not properly acquire a mature phenotype, and inducing NK cells to release TNFA and IFNG, which promotes DC maturation.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI2007P)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
2007P
Lokale Artikelnummer::
PRSI2007P
Beschreibung:
CAD peptide is used for blocking the activity of CAD antibody.
VE:
1 * 50 µG
Lieferant:
Shenandoah Biotechnology
Beschreibung:
Galectin-3 belongs to the lectin family of carbohydrate binding proteins. Galectin-3 is expressed by a wide range of cell types including activated T cells, tumor cells, macrophages, osteoclasts, fibroblasts, and epithelial cells. Galectin-3 has specific binding affinity for beta-galactoside sugar moieties and has functional roles during development, innate immunity, cell apoptosis, and tumor metastasis. Galectin-3 is associated with cancer, heart failure, stroke, and inflammation. The amino acid sequences of human and mouse Galectin-3 proteins share 80% homology.
Lieferant:
Shenandoah Biotechnology
Beschreibung:
Sonic hedgehog (SHH) is a member of a small group of hedgehog secreted proteins that are essential for development in both vertebrates and invertebrates. There are three mammalian hedgehog homologues, sonic, desert, and indian, that signal via the Patched-1 and Patched-2 receptors. SHH is a morphogen that is essential during vertebrate organogenesis and adult stem cell division.
Artikel-Nr:
(PRSI96-133)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
96-133
Lokale Artikelnummer::
PRSI96-133
Beschreibung:
CD Antigen CD27 is also known as Tumor necrosis factor receptor superfamily member 7 (TNFRSF7), which belongs to TNF-receptor superfamily. CD27 / TNFRSF7 is found in most T-lymphocytes. CD27 / TNFRSF7 is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-κB and MAPK8/JNK. CD27 has been shown to interact with SIVA1, TRAF2 and TRAF3.
VE:
1 * 200 µG
Lieferant:
Shenandoah Biotechnology
Beschreibung:
Myostatin, also known as GDF-8, is a conserved member of the TGF-beta superfamily. Myostatin is an essential regulator of skeletal muscle mass and cardiac muscle development and function. Myostatin is a secreted protein that negatively regulates skeletal muscle growth by determining muscle fiber number and size.
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Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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