15149-10G
15149-50G
SIAL15149-10GEA
155
EUR
InStock
SIAL15149-10G
SIAL15149-50G
Glycine-N,N-bis(methylenephosphonic acid) ≥98,0% (durch titrimetrische Analyse), Sigma-Aldrich®
Glycine-N,N-bis(methylenephosphonic acid)
N,N-Bis(phosphonomethyl)glycine is present in the ligand bound to human apotransferrin.
Used as a complexing agent, pK-values: pK1: ·2, pK2: 2.0, pK3: 5.20, pK4: 6.77, pK5: 10.89.
Glyphosine binds to a pocket of MHC class II molecules I-Ag7 and DQ8, and modify T cell responses to the autoantigenic insulin B chain fragment 9–23 (B:9–23) peptide. Glyphosine stimulate IL-10 production and delay onset of diabetes in non-obese NOD mice.†