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Purvalanol A 98, crystalline solid

Lieferant: CAYMAN

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CAYM14579-10EA 81 EUR InStock
CAYM14579-10 CAYM14579-50 CAYM14579-5 CAYM14579-100
Purvalanol A 98, crystalline solid
Purvalanol A
Purvalanol A is a potent, cell-permeable, and selective inhibitor of cyclin-dependent kinases (CDKs) with IC50 values of 4, 70, 35, 850, and 75 nM for cdc2/cyclin B, Cdk2/cyclin A, Cdk2/cyclin E, Cdk4/cyclin D1 and Cdk5-p35, respectively.

Purvalanol A reversibly arrests synchronized cells in the G1 and G2 phase of the cell cycle, inhibiting both cell proliferation and cell death. At 10 μM, purvalanol A potently suppresses the anchorage-independent growth of c-Src-transformed cells as well as HT-29 and SW48 human colon cancer cells.

Achtung! Bitte beachten: Not for human or veterinary use.


Formel: C₁₉H₂₅N₆OCl
MW: 388.9 g/mol
Storage Temperature: Gefrierschrank
 MDL Number: MFCD02179211
CAS-Nummer: 212844-53-6
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Spezifikation Testergebnisse
Purity ≥98%

 

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Should VWR need to supply products and/or services of different specifications, sources, and pack size to that published or ordered by the customer, VWR shall do so only after consultation with and agreement by the customer.

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