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2-(4-Chlorophenyl)oxazole-4-carboxylic+acid
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2-(4-Chlorophenyl)oxazole-4-carboxylic+acid
Artikel-Nr:
(BOSSBS-1145R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1145R-A555
Lokale Artikelnummer::
BOSSBS-1145R-A555
Beschreibung:
This gene encodes a member of the human ARF gene family, which is part of the RAS superfamily. The ARF genes encode small guanine nucleotide-binding proteins that stimulate the ADP-ribosyltransferase activity of cholera toxin and play a role in vesicular trafficking and as activators of phospholipase D. The product of this gene is localized to the plasma membrane, and regulates vesicular trafficking, remodelling of membrane lipids, and signaling pathways that lead to actin remodeling. A pseudogene of this gene is located on chromosome 7.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13557R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13557R-A680
Lokale Artikelnummer::
BOSSBS-13557R-A680
Beschreibung:
ZBT24/ZNF45
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2905R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2905R-CY5.5
Lokale Artikelnummer::
BOSSBS-2905R-CY5.5
Beschreibung:
This gene encodes a member of the low density lipoprotein (LDL) receptor gene family. LDL receptors are transmembrane cell surface proteins involved in receptor-mediated endocytosis of lipoprotein and protein ligands. The protein encoded by this gene functions as a receptor or, with Frizzled, a co-receptor for Wnt and thereby transmits the canonical Wnt/beta-catenin signaling cascade. Through its interaction with the Wnt/beta-catenin signaling cascade this gene plays a role in the regulation of cell differentiation, proliferation, and migration and the development of many cancer types. This protein undergoes gamma-secretase dependent RIP- (regulated intramembrane proteolysis) processing but the precise locations of the cleavage sites have not been determined.[provided by RefSeq, Dec 2009].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2201R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2201R-CY3
Lokale Artikelnummer::
BOSSBS-2201R-CY3
Beschreibung:
GEF-H1 is a Rho guanine nucleotide exchange factor that localizes to microtubules and regulates Rho activity in response to microtubule destabilization (loss of interaction between GEF-H1 and microtubules leads to activation of Rho). This protein has also been shown to localize to tight junctions and modulate polarized cell permeability.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9182R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9182R-A647
Lokale Artikelnummer::
BOSSBS-9182R-A647
Beschreibung:
VGLL1 is a specific coactivator for the mammalian TEFs. The mammalian TEF and the Drosophila scalloped genes belong to a conserved family of transcriptional factors that possesses a TEA/ATTS DNA binding domain.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0136R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0136R-FITC
Lokale Artikelnummer::
BOSSBS-0136R-FITC
Beschreibung:
GTP cyclohydrolase I (also designated dopa-responsive dystonia) catalyzes the conversion of GTP to D-erythro-7,8-dihydroneopterin triphosphate, the first and rate-limiting step in tetrahydrobiopterin (BH4) biosynthesis. Tetrahydrobiopterin is an essential cofactor for 3 aromatic amino acid monooxygenases: phenylalanine, tyrosine, and tryptophan hydroxylases. Animals can synthesize tetrahydrobiopterin in vivo from GTP through several enzymatic reactions.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12139R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12139R-A488
Lokale Artikelnummer::
BOSSBS-12139R-A488
Beschreibung:
A guanylate kinase is a phosphotransferase that produces ADP and GDP from the substrates ATP and GMP. SAPAP2, also known as DAP-2 (Disks large-associated protein 2) and PSD-95/SAP90-binding protein 2, is a 1054 amino acid protein that localizes to the postsynaptic membrane of neuronal cells of the brain and kidney. SAPAP2 likely acts as a signaling molecule which interacts with the human genes DLG1 and DLG4/PSD-95. The gene encoding SAPAP2, DLGAP2, maps to human chromosome 8. Consisting of nearly 146 million base pairs, chromosome 8 encodes over 800 genes and is associated with a variety of diseases and malignancies. Schizophrenia, bipolar disorder, Trisomy 8, Pfeiffer syndrome, congenital hypothyroidism, Waardenburg syndrome and some leukemias and lymphomas are thought to occur as a result of defects in specific genes that maps to chromosome 8.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0282R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0282R-A680
Lokale Artikelnummer::
BOSSBS-0282R-A680
Beschreibung:
Component of the Mediator complex, a coactivator involved in regulated gene transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. Binds to and activates cyclin-dependent kinase CDK8 that phosphorylates the CTD (C-terminal domain) of the large subunit of RNA polymerase II (RNAp II), which may inhibit the formation of a transcription initiation complex.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9337R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9337R-CY3
Lokale Artikelnummer::
BOSSBS-9337R-CY3
Beschreibung:
Ubiquitination is an important mechanism through which three classes of enzymes act in concert to target short-lived or abnormal proteins for destruction. The three classes of enzymes involved in ubiquitination are the ubiquitin-activating enzymes (E1s), the ubiquitin-conjugating enzymes (E2s) and the ubiquitin-protein ligases (E3s). MARCH3 (membrane-associated ring finger (C3HC4) 3), also known as RNF173, is a 253 amino acid multi-pass membrane protein that localizes to cytoplasmic vesicles and early endosomes and contains one RING-CH-type zinc finger. Involved in the pathway of protein modification, MARCH3 functions as an E3 ubiquitin-protein ligase that accepts a ubiquitin residue from an E2 ubiquitin-conjugating enzyme and is thought to be involved in endosomal trafficking events.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12051R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12051R-A750
Lokale Artikelnummer::
BOSSBS-12051R-A750
Beschreibung:
This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor is a ligand-gated ion channel, which when activated causes fast, depolarizing responses in neurons. It is a cation-specific, but otherwise relatively nonselective, ion channel.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8395R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8395R-HRP
Lokale Artikelnummer::
BOSSBS-8395R-HRP
Beschreibung:
FBXO29, also designated F-box/WD repeat-containing protein 8 (FBXW8), is a 598 amino acid protein that contains one 40 amino acid F-box region, making it a member of the F-box family. FBXO29 also contains five WD repeats. F-box proteins are critical components of the SCF (Skp1-CUL-1-F-box protein) type E3 ubiquitin ligase complex and are involved in substrate recognition and recruitment for ubiquitination. F-box proteins are members of a large family that regulates cell cycle, immune response, signaling cascades and developmental programs by targeting proteins, such as cyclins, cyclin-dependent kinase inhibitors, IkB-å and ∫-catenin, for degradation by the proteasome after ubiquitination. Functioning as a component of the SCF complex, FBXO29 is thought to recognize and bind to select phosphorylated proteins, thereby promoting their ubiquitination and subsequent degradation. FBXO29 exists as two isoforms as a result of alternative splicing events.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6059R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6059R-A350
Lokale Artikelnummer::
BOSSBS-6059R-A350
Beschreibung:
Immediate-early protein likely to play a role in cell growth regulation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4913R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4913R-CY3
Lokale Artikelnummer::
BOSSBS-4913R-CY3
Beschreibung:
By generating PPi, plays a role in regulating pyrophosphate levels, and functions in bone mineralization and soft tissue calcification. PPi inhibits mineralization by binding to nascent hydroxyapatite (HA) crystals, thereby preventing further growth of these crystals. Preferentially hydrolyzes ATP, but can also hydrolyze other nucleoside 5' triphosphates such as GTP, CTP, TTP and UTP to their corresponding monophosphates with release of pyrophosphate and diadenosine polyphosphates, and also 3',5'-cAMP to AMP. May also be involved in the regulation of the availability of nucleotide sugars in the endoplasmic reticulum and Golgi, and the regulation of purinergic signaling. Appears to modulate insulin sensitivity and function.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7644R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7644R
Lokale Artikelnummer::
BOSSBS-7644R
Beschreibung:
May be involved in membrane trafficking in the early secretory pathway. Inhibits BACE1 activity and amyloid precursor protein processing. May induce caspase-8 cascade and apoptosis. May favor BCL2 translocation to the mitochondria upon endoplasmic reticulum stress. In case of enteroviruses infection, RTN3 may be involved in the viral replication or pathogenesis. There are 5 isoforms.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13621R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13621R-HRP
Lokale Artikelnummer::
BOSSBS-13621R-HRP
Beschreibung:
The C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily consists of a variety of proteins that share a common protein fold and have diverse functions, including cell-cell signaling, cell adhesion, glycoprotein turnover and immune responses. CLEC-9A (C-type lectin domain family 9 member A), also known as DNGR1 (dendritic cell natural killer lectin group receptor 1), is a 241 amino acid single-pass type II membrane protein that contains one C-type lectin domain and belongs to the CTL/CTLD superfamily. Expressed in myeloid lineage cells, brain, spleen and thymus, CLEC-9A is a group V C-type lectin-like receptor (CTLR) that acts as an activation receptor. The gene encoding CLEC-9A maps to human chromosome 12p13.2 and mouse chromosome 6 F3.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6097R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6097R-FITC
Lokale Artikelnummer::
BOSSBS-6097R-FITC
Beschreibung:
RSRC2 (arginine/serine-rich coiled-coil 2) possibly plays a role in cell proliferation and may be a novel tumor suppressor of esophageal cancer cell growth.
VE:
1 * 100 µl
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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