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tert-Butyl+2-amino-4-(trifluoromethyl)benzoate
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tert-Butyl+2-amino-4-(trifluoromethyl)benzoate
Artikel-Nr:
(USBII7661-15E)
Lieferant:
US Biological
Hersteller-Artikelnummer::
I7661-15E
Lokale Artikelnummer::
USBII7661-15E
Beschreibung:
Anti-Insulin-Like Growth Factor II Rabbit Polyclonal Antibody (Biotin)
VE:
1 * 50 µG
Artikel-Nr:
(BOSSBS-6972R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6972R-A350
Lokale Artikelnummer::
BOSSBS-6972R-A350
Beschreibung:
RNA polymerase II (Pol II) is an enzyme that is composed of twelve subunits and is responsible for the transcription of protein-coding genes. Transcription initiation requires Pol II-mediated recruitment of transcription machinery to a target promoter, thereby allowing transcription to begin. The largest subunit of Pol II (referred to as RPB1 or RPB205) is a 1,840 amino acid protein that contains one C2H2-type zinc finger and a C-terminal domain comprised of several heptapeptide repeats. Although Pol II function requires the cooperation of all twelve subunits, the largest subunit conveys Pol II catalytic activity and, together with the second largest subunit, forms the active center of the Pol II enzyme. Additionally, the large subunit participates in forming the DNA-binding domain of Pol II, a groove that is necessary for transcription of the DNA template. Without proper function of the large subunit, mRNA synthesis and subsequent transcription elongation cannot occur.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6972R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6972R-A647
Lokale Artikelnummer::
BOSSBS-6972R-A647
Beschreibung:
RNA polymerase II (Pol II) is an enzyme that is composed of twelve subunits and is responsible for the transcription of protein-coding genes. Transcription initiation requires Pol II-mediated recruitment of transcription machinery to a target promoter, thereby allowing transcription to begin. The largest subunit of Pol II (referred to as RPB1 or RPB205) is a 1,840 amino acid protein that contains one C2H2-type zinc finger and a C-terminal domain comprised of several heptapeptide repeats. Although Pol II function requires the cooperation of all twelve subunits, the largest subunit conveys Pol II catalytic activity and, together with the second largest subunit, forms the active center of the Pol II enzyme. Additionally, the large subunit participates in forming the DNA-binding domain of Pol II, a groove that is necessary for transcription of the DNA template. Without proper function of the large subunit, mRNA synthesis and subsequent transcription elongation cannot occur.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0282R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0282R-FITC
Lokale Artikelnummer::
BOSSBS-0282R-FITC
Beschreibung:
Component of the Mediator complex, a coactivator involved in regulated gene transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. Binds to and activates cyclin-dependent kinase CDK8 that phosphorylates the CTD (C-terminal domain) of the large subunit of RNA polymerase II (RNAp II), which may inhibit the formation of a transcription initiation complex.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0282R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0282R-A488
Lokale Artikelnummer::
BOSSBS-0282R-A488
Beschreibung:
Component of the Mediator complex, a coactivator involved in regulated gene transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. Binds to and activates cyclin-dependent kinase CDK8 that phosphorylates the CTD (C-terminal domain) of the large subunit of RNA polymerase II (RNAp II), which may inhibit the formation of a transcription initiation complex.
VE:
1 * 100 µl
Lieferant:
Thermo Scientific
Beschreibung:
Zinkoxid 99.999% (bezogen auf die Metalle der seltenen Erden)
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
Oxaliplatin inhibits DNA synthesis by conforming DNA adducts.
Lieferant:
Alfa Aesar
Beschreibung:
Zinkbromid ≥99,9% (Metall-Basis)
Artikel-Nr:
(40224.18)
Lieferant:
Alfa Aesar
Hersteller-Artikelnummer::
40224.18
Lokale Artikelnummer::
ALFA40224.18
Beschreibung:
Cobaltselenid ≥99% (Metall-Basis)
VE:
1 * 50 g
Artikel-Nr:
(BOSSBS-5034R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5034R-A750
Lokale Artikelnummer::
BOSSBS-5034R-A750
Beschreibung:
Apolipoprotein A II is the second most abundant protein of the high density lipoprotein particles. The apolipoprotein A II gene consists of 4 exons and 3 introns. The four exons encode the 5' untranslated region, pre peptide, a short N terminal domain and a C terminal domain composed of a variable number of lipid binding amphipathic helices. Familial apolipoprotein A II deficiency may result from a splice junction alteration which blocks splicing of intron 3 from the primary transcript and result in the formation of a non functional mRNA.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5034R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5034R-CY7
Lokale Artikelnummer::
BOSSBS-5034R-CY7
Beschreibung:
Apolipoprotein A II is the second most abundant protein of the high density lipoprotein particles. The apolipoprotein A II gene consists of 4 exons and 3 introns. The four exons encode the 5' untranslated region, pre peptide, a short N terminal domain and a C terminal domain composed of a variable number of lipid binding amphipathic helices. Familial apolipoprotein A II deficiency may result from a splice junction alteration which blocks splicing of intron 3 from the primary transcript and result in the formation of a non functional mRNA.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5034R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5034R-HRP
Lokale Artikelnummer::
BOSSBS-5034R-HRP
Beschreibung:
Apolipoprotein A II is the second most abundant protein of the high density lipoprotein particles. The apolipoprotein A II gene consists of 4 exons and 3 introns. The four exons encode the 5' untranslated region, pre peptide, a short N terminal domain and a C terminal domain composed of a variable number of lipid binding amphipathic helices. Familial apolipoprotein A II deficiency may result from a splice junction alteration which blocks splicing of intron 3 from the primary transcript and result in the formation of a non functional mRNA.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11988R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11988R-CY3
Lokale Artikelnummer::
BOSSBS-11988R-CY3
Beschreibung:
Brain-specific neurabin I (neural tissue-specific F-actin binding protein I) is highly concentrated in the synapse of developed neurons; it localizes in the growth cone lamellipodia during neuronal development (1). Suppression of endogenous neurabin in rat hippocampal neurons inhibits neurite formation (1). Neurabin I recruits active PP1 via a PP1-docking sequence; mutation of the PP1-binding motif halts filopodia and restores stress fibers in neurabin I-expressing cells (2,3). Neurabin II (Spinophilin) is ubiquitously expressed but is abundantly expressed in brain (4). Neurabin II localizes to neuronal dentritic spines, which are the specialized protrusions from dendritic shafts that receive most of the excitatory input in the CNS (5). Neurabin II may regulate dendritic spine properties as neurabin II(-) mice have increased spine density during development in vitro and exhibit altered filopodial formation in cultured cells (5). Neurabin may also play a role in glutamatergic transmission as Neurabin II(-) mice exhibit reduced long-term depression and resistance to kainate-induced seizures and neronal apoptosis (5). Neurabin II complexes with the catalytic subunit of protein phosphatase-1 (PP1) in vitro thus modulating the activity of PP1 (4).
VE:
1 * 100 µl
Lieferant:
Alfa Aesar
Beschreibung:
Zinkselenid ≥99,99% (Metall-Basis)
Artikel-Nr:
(45469.36)
Lieferant:
Alfa Aesar
Hersteller-Artikelnummer::
45469.36
Lokale Artikelnummer::
ALFA45469.36
Beschreibung:
Zinkoxid, HiFUEL® A310 zum Entfernen von Schwefel
VE:
1 * 500 g
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Dieses Produkt kann nur an eine Lieferadresse versandt werden die über die entsprechende Lizenzen verfügt. Für weitere Hilfe bitte kontaktieren Sie Ihr VWR Vertriebszentrum.
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