(+\/-)-3-(trans-2-(Trifluoromethyl)cyclopropyl)benzoic+acid
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
5-Bromo-2,4-difluorobenzotrifluoride
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
Diethyl 2-(3-trifluoromethylphenyl)malonate
Lieferant:
Alfa Aesar
Beschreibung:
α,α,α-Trifluor-4-tolualdehyd ≥97%
Lieferant:
Alfa Aesar
Beschreibung:
α,α,α-Trifluor-3-tolualdehyd ≥97%
Artikel-Nr:
(BLDPBD257892-1G)
Lieferant:
BLD PHARMATECH GMBH
Hersteller-Artikelnummer::
BD257892-1G
Lokale Artikelnummer::
BLDPBD257892-1G
Beschreibung:
3-Brom-5-iodbenzotrifluorid 97%
VE:
1 * 1 g
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
α'-Chlor-α,α,α-trifluor-p-xylol 98%
Artikel-Nr:
(BOSSBS-0483R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0483R-A555
Lokale Artikelnummer::
BOSSBS-0483R-A555
Beschreibung:
Histones are highly conserved proteins that serve as the structural scaffold for the organization of nuclear DNA into chromatin. The four core histones, H2A, H2B, H3, and H4, assemble into an octamer (2 molecules of each). Subsequently, 146 base pairs of DNA are wrapped around the octamer, forming a nucleosome, the basic subunit of chromatin. Histone modifications regulate DNA transcription, repair, recombination, and replication. The most commonly studied modifications are acetylation, phosphorylation, methylation, and ubiquitination. These modifications can alter local chromatin architecture, or recruit trans-acting factors that recognize specific histone modifications (the "histone code" hypothesis). Trimethylation of histone H3 on Lys9 (H3K9me3) is one of the most highly studied epigenetic marks. H3K9me3 functions in the repression of euchromatic genes, and in epigenetic control of heterochromatin assembly, most likely via acting as a recognition motif for the binding of chromatin-associated proteins, such as Swi6 or HP1Alpha/Beta. The enzymes responsible for H3K9me3 formation are SUV39H1 and SUV39H2.
VE:
1 * 100 µl
Lieferant:
Alfa Aesar
Beschreibung:
α,α,α,3-Tetrafluortoluol ≥99%
Lieferant:
Biotium
Beschreibung:
Cytochrome C is a well-characterized mobile electron transport protein that is essential to energy conversion in all aerobic organisms. In mammalian cells, this highly conserved protein is normally localized to the mitochondrial inter-membrane space. More recent studies have identified cytosolic cytochrome c as a factor necessary for activation of apoptosis. During apoptosis, cytochrome c is trans-located from the mitochondrial membrane to the cytosol, where it is required for activation of caspase-3 (CPP32). Overexpression of Bcl-2 has been shown to prevent the translocation of cytochrome c, thereby blocking the apoptotic process. Overexpression of Bax has been shown to induce the release of cytochrome c and to induce cell death. The release of cytochrome c from the mitochondria is thought to trigger an apoptotic cascade, whereby Apaf-1 binds to Apaf-3 (caspase-9) in a cytochrome c-dependent manner, leading to caspase-9 cleavage of caspase-3. This MAb recognizes total cytochrome C which includes both apocytochrome (i.e. cytochrome in the cytosol without heme attached) and holocytochrome (i.e cytochrome in the mitochondria with heme attached).
Artikel-Nr:
(BOSSBS-11292R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11292R-HRP
Lokale Artikelnummer::
BOSSBS-11292R-HRP
Beschreibung:
The Hox proteins play a role in development and cellular differentiation by regulating downstream target genes. Specifically, the Hox proteins direct DNA-protein and protein-protein interactions that assist in determining the morphologic features associated with the anterior-posterior body axis. The mammalian HOX gene complex consists of 39 genes that are located on four linkage groups, which are dispersed over four chromosomes. HOX genes that occupy the same relative position along the 5’ to 3’ coordinate (trans-paralogous genes) are more similar in sequence and expression pattern than adjacent HOX genes on the same chromosome. HoxA3, in conjunction with Pax1, mediates the development of the thymus, parathyroid gland, and carotid body. Its expression in the third pharyngeal arch and pouch is required for development of the third arch artery, and homozygous null HoxA3 mutants lack the carotid body. HoxA3 also regulates hindbrain development by controlling the axon projection pattern of motor neurons and sensory neurons of the proximal and distal ganglia.
VE:
1 * 100 µl
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
Intermediate for the synthesis of several pharmaceuticals including Bendrofluazide
Artikel-Nr:
(USBI132441)
Lieferant:
US Biological
Hersteller-Artikelnummer::
132441
Lokale Artikelnummer::
USBI132441
Beschreibung:
Anti-Retinol Dehydrogenase 12 Rabbit Polyclonal Antibody
VE:
1 * 100 µG
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
α,α,α,2-Tetrafluortoluol 97%
Lieferant:
Alfa Aesar
Beschreibung:
α'-Brom-α,α,α-trifluor-m-xylol ≥98%
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
2,2-Dichloro-3,3,3-trifluoropropan-1-ol
Lieferant:
Alfa Aesar
Beschreibung:
α,α,α,4-Tetrafluortoluol ≥98%
Preis auf Anfrage
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