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(+\/-)-3-(trans-2-(Trifluoromethyl)cyclopropyl)benzoic+acid
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(+\/-)-3-(trans-2-(Trifluoromethyl)cyclopropyl)benzoic+acid
Artikel-Nr:
(BOSSBS-3703R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3703R-FITC
Lokale Artikelnummer::
BOSSBS-3703R-FITC
Beschreibung:
Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. In cooperation with mitochondrial PPIF is involved in activating oxidative stress-induced necrosis; the function is largely independent of transcription. Induces the transcription of long intergenic non-coding RNA p21 (lincRNA-p21) and lincRNA-Mkln1. LincRNA-p21 participates in TP53-dependent transcriptional repression leading to apoptosis and seem to have to effect on cell-cycle regulation. Implicated in Notch signaling cross-over. Prevents CDK7 kinase activity when associated to CAK complex in response to DNA damage, thus stopping cell cycle progression. Isoform 2 enhances the transactivation activity of isoform 1 from some but not all TP53-inducible promoters. Isoform 4 suppresses transactivation activity and impairs growth suppression mediated by isoform 1. Isoform 7 inhibits isoform 1-mediated apoptosis.
VE:
1 * 100 µl
Artikel-Nr:
(APOSPC01683-25G)
Lieferant:
APOLLO SCIENTIFIC
Hersteller-Artikelnummer::
PC01683-25G
Lokale Artikelnummer::
APOSPC01683-25G
Beschreibung:
1-Methyl-1-propylpyrrolidinium bis(trifluoromethanesulphonyl)imide 98%
VE:
1 * 25 g
Artikel-Nr:
(BOSSBS-3704R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3704R-A488
Lokale Artikelnummer::
BOSSBS-3704R-A488
Beschreibung:
Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. In cooperation with mitochondrial PPIF is involved in activating oxidative stress-induced necrosis; the function is largely independent of transcription. Induces the transcription of long intergenic non-coding RNA p21 (lincRNA-p21) and lincRNA-Mkln1. LincRNA-p21 participates in TP53-dependent transcriptional repression leading to apoptosis and seem to have to effect on cell-cycle regulation. Implicated in Notch signaling cross-over. Prevents CDK7 kinase activity when associated to CAK complex in response to DNA damage, thus stopping cell cycle progression. Isoform 2 enhances the transactivation activity of isoform 1 from some but not all TP53-inducible promoters. Isoform 4 suppresses transactivation activity and impairs growth suppression mediated by isoform 1. Isoform 7 inhibits isoform 1-mediated apoptosis. Regulates the circadian clock by repressing CLOCK-ARNTL/BMAL1-mediated transcriptional activation of PER2 (PubMed:24051492).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3704R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3704R-HRP
Lokale Artikelnummer::
BOSSBS-3704R-HRP
Beschreibung:
Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. In cooperation with mitochondrial PPIF is involved in activating oxidative stress-induced necrosis; the function is largely independent of transcription. Induces the transcription of long intergenic non-coding RNA p21 (lincRNA-p21) and lincRNA-Mkln1. LincRNA-p21 participates in TP53-dependent transcriptional repression leading to apoptosis and seem to have to effect on cell-cycle regulation. Implicated in Notch signaling cross-over. Prevents CDK7 kinase activity when associated to CAK complex in response to DNA damage, thus stopping cell cycle progression. Isoform 2 enhances the transactivation activity of isoform 1 from some but not all TP53-inducible promoters. Isoform 4 suppresses transactivation activity and impairs growth suppression mediated by isoform 1. Isoform 7 inhibits isoform 1-mediated apoptosis. Regulates the circadian clock by repressing CLOCK-ARNTL/BMAL1-mediated transcriptional activation of PER2 (PubMed:24051492).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3704R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3704R-CY3
Lokale Artikelnummer::
BOSSBS-3704R-CY3
Beschreibung:
Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. In cooperation with mitochondrial PPIF is involved in activating oxidative stress-induced necrosis; the function is largely independent of transcription. Induces the transcription of long intergenic non-coding RNA p21 (lincRNA-p21) and lincRNA-Mkln1. LincRNA-p21 participates in TP53-dependent transcriptional repression leading to apoptosis and seem to have to effect on cell-cycle regulation. Implicated in Notch signaling cross-over. Prevents CDK7 kinase activity when associated to CAK complex in response to DNA damage, thus stopping cell cycle progression. Isoform 2 enhances the transactivation activity of isoform 1 from some but not all TP53-inducible promoters. Isoform 4 suppresses transactivation activity and impairs growth suppression mediated by isoform 1. Isoform 7 inhibits isoform 1-mediated apoptosis. Regulates the circadian clock by repressing CLOCK-ARNTL/BMAL1-mediated transcriptional activation of PER2 (PubMed:24051492).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3704R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3704R-A555
Lokale Artikelnummer::
BOSSBS-3704R-A555
Beschreibung:
Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. In cooperation with mitochondrial PPIF is involved in activating oxidative stress-induced necrosis; the function is largely independent of transcription. Induces the transcription of long intergenic non-coding RNA p21 (lincRNA-p21) and lincRNA-Mkln1. LincRNA-p21 participates in TP53-dependent transcriptional repression leading to apoptosis and seem to have to effect on cell-cycle regulation. Implicated in Notch signaling cross-over. Prevents CDK7 kinase activity when associated to CAK complex in response to DNA damage, thus stopping cell cycle progression. Isoform 2 enhances the transactivation activity of isoform 1 from some but not all TP53-inducible promoters. Isoform 4 suppresses transactivation activity and impairs growth suppression mediated by isoform 1. Isoform 7 inhibits isoform 1-mediated apoptosis. Regulates the circadian clock by repressing CLOCK-ARNTL/BMAL1-mediated transcriptional activation of PER2 (PubMed:24051492).
VE:
1 * 100 µl
Artikel-Nr:
(BSBTA01308)
Lieferant:
BosterBio
Hersteller-Artikelnummer::
A01308
Lokale Artikelnummer::
BSBTA01308
Beschreibung:
Rabbit IgG polyclonal antibody for Peptidyl-prolyl cis-trans isomerase A(PPIA) detection. Tested with WB, IHC-P in Human;Mouse;Rat.
VE:
1 * 100 µG
Artikel-Nr:
(REST36290)
Lieferant:
Restek
Hersteller-Artikelnummer::
36290
Lokale Artikelnummer::
REST36290
Beschreibung:
The United States Pharmacopeia (USP)<467> residual solvents is a widely used compendial method intended for identifying and quantifying residual solvents in drug substances, drug products, and excipients.
VE:
1 * 1 Ampull
Lieferant:
Sigma-Aldrich
Beschreibung:
Capsaisin, Sigma-Aldrich®
Lieferant:
Sigma-Aldrich
Beschreibung:
Isoeugenol (Gemisch der cis- und trans-Isomeren), Sigma-Aldrich®
Artikel-Nr:
(211275-100MG)
Lieferant:
Merck Millipore (Calbiochem)
Hersteller-Artikelnummer::
211275-100MG
Lokale Artikelnummer::
CALB211275-100MG
Beschreibung:
Capsaisin, Calbiochem®
VE:
1 * 100 mg
Artikel-Nr:
(ACRO467881000)
Lieferant:
Thermo Scientific
Hersteller-Artikelnummer::
467881000
Lokale Artikelnummer::
ACRO467881000
Beschreibung:
Chemical probes can be used to help establish the
relationship between a molecular target and the broader biological consequences of modulating that target in cells or organisms.
VE:
1 * 100 mg
Artikel-Nr:
(BOSSBS-0033R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0033R-FITC
Lokale Artikelnummer::
BOSSBS-0033R-FITC
Beschreibung:
Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. In cooperation with mitochondrial PPIF is involved in activating oxidative stress-induced necrosis; the function is largely independent of transcription. Induces the transcription of long intergenic non-coding RNA p21 (lincRNA-p21) and lincRNA-Mkln1. LincRNA-p21 participates in TP53-dependent transcriptional repression leading to apoptosis and seem to have to effect on cell-cycle regulation. Implicated in Notch signaling cross-over. Prevents CDK7 kinase activity when associated to CAK complex in response to DNA damage, thus stopping cell cycle progression. Isoform 2 enhances the transactivation activity of isoform 1 from some but not all TP53-inducible promoters. Isoform 4 suppresses transactivation activity and impairs growth suppression mediated by isoform 1. Isoform 7 inhibits isoform 1-mediated apoptosis.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1650R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1650R-A750
Lokale Artikelnummer::
BOSSBS-1650R-A750
Beschreibung:
Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. In cooperation with mitochondrial PPIF is involved in activating oxidative stress-induced necrosis; the function is largely independent of transcription. Induces the transcription of long intergenic non-coding RNA p21 (lincRNA-p21) and lincRNA-Mkln1. LincRNA-p21 participates in TP53-dependent transcriptional repression leading to apoptosis and seem to have to effect on cell-cycle regulation. Implicated in Notch signaling cross-over. Prevents CDK7 kinase activity when associated to CAK complex in response to DNA damage, thus stopping cell cycle progression. Isoform 2 enhances the transactivation activity of isoform 1 from some but not all TP53-inducible promoters. Isoform 4 suppresses transactivation activity and impairs growth suppression mediated by isoform 1. Isoform 7 inhibits isoform 1-mediated apoptosis.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3703R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3703R-A647
Lokale Artikelnummer::
BOSSBS-3703R-A647
Beschreibung:
Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. In cooperation with mitochondrial PPIF is involved in activating oxidative stress-induced necrosis; the function is largely independent of transcription. Induces the transcription of long intergenic non-coding RNA p21 (lincRNA-p21) and lincRNA-Mkln1. LincRNA-p21 participates in TP53-dependent transcriptional repression leading to apoptosis and seem to have to effect on cell-cycle regulation. Implicated in Notch signaling cross-over. Prevents CDK7 kinase activity when associated to CAK complex in response to DNA damage, thus stopping cell cycle progression. Isoform 2 enhances the transactivation activity of isoform 1 from some but not all TP53-inducible promoters. Isoform 4 suppresses transactivation activity and impairs growth suppression mediated by isoform 1. Isoform 7 inhibits isoform 1-mediated apoptosis.
VE:
1 * 100 µl
Artikel-Nr:
(SIAL268976-5G)
Lieferant:
Sigma-Aldrich
Hersteller-Artikelnummer::
268976-5G
Lokale Artikelnummer::
SIAL268976-5G
Beschreibung:
3-Methyl-1,3-pentadien (Gemisch der cis- und trans-Isomeren), Sigma-Aldrich®
VE:
1 * 5 g
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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