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4,4-Dimethylcyclohexa-1,5-dienylborons\\u00E4ure+Mononatriumsalz
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4,4-Dimethylcyclohexa-1,5-dienylborons\\u00E4ure+Mononatriumsalz
Artikel-Nr:
(BOSSBS-4877R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4877R-A555
Lokale Artikelnummer::
BOSSBS-4877R-A555
Beschreibung:
The complement factor C3 consists of an alpha and a beta chain. C3 is a central factor in the complement cascade. It is central to the alternative pathway that leads to the C3 convertase C3bBb. The classical mannose binding lectin activation pathway leads to the C3 convertase C4b2a. These convertases cleave C3 resulting in C3a and C3b. Further degradation leads to the formation of the alpha chain products C3d, C3g and C3c. C3 is an acute phase protein that is produced by a wide range of tissues, including renal epithelial cells and hepatocytes.
VE:
1 * 100 µl
Artikel-Nr:
(BNUM0363-50)
Lieferant:
Biotium
Hersteller-Artikelnummer::
BNUM0363-50
Lokale Artikelnummer::
BTIUBNUM0363-50
Beschreibung:
CD147 is a transmembrane glycoprotein of the immunoglobulin superfamily. It is expressed more intensely on thymocytes than on mature peripheral blood T cells. CD147 is important in spermatogenesis, embryo implantation, neural network formation, and tumor progression. CD147 is involved in the regulation of matrix remodeling at the epidermal-dermal interface. It stimulates the production of interstitial collagenase, gelatinase A, stromelysin-1 and various metalloproteinases (MMPs) by fibroblasts. These enzymes, which are typically increased during tissue degradation and wound healing, are important factors in cancer invasion and metastasis.
VE:
1 * 50 µl
Artikel-Nr:
(BOSSBS-3484R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3484R-CY5.5
Lokale Artikelnummer::
BOSSBS-3484R-CY5.5
Beschreibung:
Receptor-regulated SMAD (R-SMAD) that is an intracellular signal transducer and transcriptional modulator activated by TGF-beta (transforming growth factor) and activin type 1 receptor kinases. Binds the TRE element in the promoter region of many genes that are regulated by TGF-beta and, on formation of the SMAD2/SMAD4 complex, activates transcription. May act as a tumor suppressor in colorectal carcinoma. Positively regulates PDPK1 kinase activity by stimulating its dissociation from the 14-3-3 protein YWHAQ which acts as a negative regulator.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1638R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1638R-FITC
Lokale Artikelnummer::
BOSSBS-1638R-FITC
Beschreibung:
Potent inhibitor of the complement membrane attack complex (MAC) action. Acts by binding to the C8 and/or C9 complements of the assembling MAC, thereby preventing incorporation of the multiple copies of C9 required for complete formation of the osmolytic pore. This inhibitor appears to be species-specific. Involved in signal transduction for T-cell activation complexed to a protein tyrosine kinase. The soluble form from urine retains its specific complement binding activity, but exhibits greatly reduced ability to inhibit MAC assembly on cell membranes.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5034R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5034R-FITC
Lokale Artikelnummer::
BOSSBS-5034R-FITC
Beschreibung:
Apolipoprotein A II is the second most abundant protein of the high density lipoprotein particles. The apolipoprotein A II gene consists of 4 exons and 3 introns. The four exons encode the 5' untranslated region, pre peptide, a short N terminal domain and a C terminal domain composed of a variable number of lipid binding amphipathic helices. Familial apolipoprotein A II deficiency may result from a splice junction alteration which blocks splicing of intron 3 from the primary transcript and result in the formation of a non functional mRNA.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3484R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3484R-CY5
Lokale Artikelnummer::
BOSSBS-3484R-CY5
Beschreibung:
Receptor-regulated SMAD (R-SMAD) that is an intracellular signal transducer and transcriptional modulator activated by TGF-beta (transforming growth factor) and activin type 1 receptor kinases. Binds the TRE element in the promoter region of many genes that are regulated by TGF-beta and, on formation of the SMAD2/SMAD4 complex, activates transcription. May act as a tumor suppressor in colorectal carcinoma. Positively regulates PDPK1 kinase activity by stimulating its dissociation from the 14-3-3 protein YWHAQ which acts as a negative regulator.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4874R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4874R-FITC
Lokale Artikelnummer::
BOSSBS-4874R-FITC
Beschreibung:
The complement factor C3 consists of an alpha and a beta chain. C3 is a central factor in the complement cascade. It is central to the alternative pathway that leads to the C3 convertase C3bBb. The classical mannose binding lectin activation pathway leads to the C3 convertase C4b2a. These convertases cleave C3 resulting in C3a and C3b. Further degradation leads to the formation of the alpha chain products C3d, C3g and C3c. C3 is an acute phase protein that is produced by a wide range of tissues, including renal epithelial cells and hepatocytes.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4875R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4875R-CY3
Lokale Artikelnummer::
BOSSBS-4875R-CY3
Beschreibung:
The complement factor C3 consists of an alpha and a beta chain. C3 is a central factor in the complement cascade. It is central to the alternative pathway that leads to the C3 convertase C3bBb. The classical mannose binding lectin activation pathway leads to the C3 convertase C4b2a. These convertases cleave C3 resulting in C3a and C3b. Further degradation leads to the formation of the alpha chain products C3d, C3g and C3c. C3 is an acute phase protein that is produced by a wide range of tissues, including renal epithelial cells and hepatocytes.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4877R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4877R-CY7
Lokale Artikelnummer::
BOSSBS-4877R-CY7
Beschreibung:
The complement factor C3 consists of an alpha and a beta chain. C3 is a central factor in the complement cascade. It is central to the alternative pathway that leads to the C3 convertase C3bBb. The classical mannose binding lectin activation pathway leads to the C3 convertase C4b2a. These convertases cleave C3 resulting in C3a and C3b. Further degradation leads to the formation of the alpha chain products C3d, C3g and C3c. C3 is an acute phase protein that is produced by a wide range of tissues, including renal epithelial cells and hepatocytes.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6299R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6299R-CY5.5
Lokale Artikelnummer::
BOSSBS-6299R-CY5.5
Beschreibung:
PRUNE, the human homologue of the Drosophila gene, is located in 1q21.3, a region highly amplified in human sarcomas, malignant tumours of mesenchymal origin. Human prune (h-prune), a phosphoesterase DHH family appertaining protein, physically interacts with nm23-H1, a metastasis suppressor gene. h-prune is involved in cellular motility and metastasis formation. Metastatic breast cancers were found to overexpress h-prune; h-prune was also found to be highly expressed in colorectal and pancreatic cancers. Hence h-prune is considered useful as a marker for tumor aggressiveness.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2809R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2809R-A350
Lokale Artikelnummer::
BOSSBS-2809R-A350
Beschreibung:
Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Involved in muscle maturation via its interaction with the myocyte enhancer factors such as MEF2A, MEF2C and MEF2D. Involved in the MTA1-mediated epigenetic regulation of ESR1 expression in breast cancer.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2652R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2652R-CY5.5
Lokale Artikelnummer::
BOSSBS-2652R-CY5.5
Beschreibung:
Sphingosine-1-phosphate (SPP) is a novel lipid messenger with both intracellular and extracellular functions. Intracellularly, it regulates proliferation and survival, and extracellularly, it is a ligand for EDG1 (MIM 601974). Various stimuli increase cellular levels of SPP by activation of sphingosine kinase (SPHK), the enzyme that catalyzes the phosphorylation of sphingosine. Competitive inhibitors of SPHK block formation of SPP and selectively inhibit cellular proliferation induced by a variety of factors, including platelet-derived growth factor (e.g., MIM 173430) and serum.[supplied by OMIM].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4876R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4876R-A488
Lokale Artikelnummer::
BOSSBS-4876R-A488
Beschreibung:
The complement factor C3 consists of an alpha and a beta chain. C3 is a central factor in the complement cascade. It is central to the alternative pathway that leads to the C3 convertase C3bBb. The classical mannose binding lectin activation pathway leads to the C3 convertase C4b2a. These convertases cleave C3 resulting in C3a and C3b. Further degradation leads to the formation of the alpha chain products C3d, C3g and C3c. C3 is an acute phase protein that is produced by a wide range of tissues, including renal epithelial cells and hepatocytes.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0932R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0932R-CY7
Lokale Artikelnummer::
BOSSBS-0932R-CY7
Beschreibung:
This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. Two transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2809R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2809R-CY7
Lokale Artikelnummer::
BOSSBS-2809R-CY7
Beschreibung:
Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Involved in muscle maturation via its interaction with the myocyte enhancer factors such as MEF2A, MEF2C and MEF2D. Involved in the MTA1-mediated epigenetic regulation of ESR1 expression in breast cancer.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6638R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6638R
Lokale Artikelnummer::
BOSSBS-6638R
Beschreibung:
EVC2 is an integral membrane protein that plays a vital role in bone formation and skeletal development. Defects in EVC2 are a cause of Ellis-van Creveld syndrome (EVC), also known as chondroectodermal dysplasia. EVC is an autosomal recessive disorder characterized by the clinical tetrad of chondrodystrophy, polydactyly, ectodermal dysplasia and cardiac anomalies. Patients manifest short-limb dwarfism, short ribs, postaxial polydactyly and dysplastic nails and teeth. Congenital heart defects, most commonly an atrioventricular septal defect, are observed in 60% of affected individuals.
VE:
1 * 100 µl
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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