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N1-Methylbenzene-1,2-diamine dihydrochloride
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N1-Methylbenzene-1,2-diamine dihydrochloride
Artikel-Nr:
(BOSSBS-11466R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11466R-FITC
Lokale Artikelnummer::
BOSSBS-11466R-FITC
Beschreibung:
Cell surface protein involved in cell-cell-interactions, exocytosis of secretory granules and regulation of signal transmission. Function is isoform-specific. Alpha-type isoforms have a long N-terminus with six laminin G-like domains and play an important role in synaptic signal transmission. Alpha-type isoforms play a role in the regulation of calcium channel activity and Ca(2+)-triggered neurotransmitter release at synapses and at neuromuscular junctions. They play an important role in Ca(2+)-triggered exocytosis of secretory granules in pituitary gland. They may effect their functions at synapses and in endocrine cells via their interactions with proteins from the exocytotic machinery. Likewise, alpha-type isoforms play a role in regulating the activity of postsynaptic NMDA receptors, a subtype of glutamate-gated ion channels. Both alpha-type and beta-type isoforms may play a role in the formation or maintenance of synaptic junctions via their calcium-dependent interactions (via the extracellular domains) with neuroligin family members, CBLN1 or CBLN2. In vitro, triggers the de novo formation of presynaptic structures. May be involved in specification of excitatory synapses. Alpha-type isoforms were first identified as receptors for alpha-latrotoxin from spider venom (By similarity).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4938R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4938R-A750
Lokale Artikelnummer::
BOSSBS-4938R-A750
Beschreibung:
Chemoattractant active on T-lymphocytes, monocytes, but not neutrophils. Activates the C-X-C chemokine receptor CXCR4 to induce a rapid and transient rise in the level of intracellular calcium ions and chemotaxis. Also binds to atypical chemokine receptor ACKR3, which activates the beta-arrestin pathway and acts as a scavenger receptor for SDF-1. SDF-1-beta(3-72) and SDF-1-alpha(3-67) show a reduced chemotactic activity. Binding to cell surface proteoglycans seems to inhibit formation of SDF-1-alpha(3-67) and thus to preserve activity on local sites. Acts as a positive regulator of monocyte migration and a negative regulator of monocyte adhesion via the LYN kinase. Stimulates migration of monocytes and T-lymphocytes through its receptors, CXCR4 and ACKR3, and decreases monocyte adherence to surfaces coated with ICAM-1, a ligand for beta-2 integrins. SDF1A/CXCR4 signaling axis inhibits beta-2 integrin LFA-1 mediated adhesion of monocytes to ICAM-1 through LYN kinase. Inhibits CXCR4-mediated infection by T-cell line-adapted HIV-1. Plays a protective role after myocardial infarction. Induces down-regulation and internalization of ACKR3 expressed in various cells. Has several critical functions during embryonic development; required for B-cell lymphopoiesis, myelopoiesis in bone marrow and heart ventricular septum formation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4938R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4938R-FITC
Lokale Artikelnummer::
BOSSBS-4938R-FITC
Beschreibung:
Chemoattractant active on T-lymphocytes, monocytes, but not neutrophils. Activates the C-X-C chemokine receptor CXCR4 to induce a rapid and transient rise in the level of intracellular calcium ions and chemotaxis. Also binds to atypical chemokine receptor ACKR3, which activates the beta-arrestin pathway and acts as a scavenger receptor for SDF-1. SDF-1-beta(3-72) and SDF-1-alpha(3-67) show a reduced chemotactic activity. Binding to cell surface proteoglycans seems to inhibit formation of SDF-1-alpha(3-67) and thus to preserve activity on local sites. Acts as a positive regulator of monocyte migration and a negative regulator of monocyte adhesion via the LYN kinase. Stimulates migration of monocytes and T-lymphocytes through its receptors, CXCR4 and ACKR3, and decreases monocyte adherence to surfaces coated with ICAM-1, a ligand for beta-2 integrins. SDF1A/CXCR4 signaling axis inhibits beta-2 integrin LFA-1 mediated adhesion of monocytes to ICAM-1 through LYN kinase. Inhibits CXCR4-mediated infection by T-cell line-adapted HIV-1. Plays a protective role after myocardial infarction. Induces down-regulation and internalization of ACKR3 expressed in various cells. Has several critical functions during embryonic development; required for B-cell lymphopoiesis, myelopoiesis in bone marrow and heart ventricular septum formation.
VE:
1 * 100 µl
Artikel-Nr:
(BLDPBD89489-5G)
Lieferant:
BLD PHARMATECH GMBH
Hersteller-Artikelnummer::
BD89489-5G
Lokale Artikelnummer::
BLDPBD89489-5G
Beschreibung:
2-Amino-6-ethylpyrimidin-4-ol 95%
VE:
1 * 5 g
Lieferant:
Thermo Scientific
Beschreibung:
Formaldehyddiethylacetal 99% stabilisiert, rein
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
4-Ethylphenylisocyanat 95%
Lieferant:
VWR Chemicals
Beschreibung:
Acetonitril ≥99,9%, HiPerSolv CHROMANORM®, Gradienten-Qualität für die HPLC
Artikel-Nr:
(BOSSBS-8878R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8878R-CY5
Lokale Artikelnummer::
BOSSBS-8878R-CY5
Beschreibung:
Ubiquitin-like modifier involved in formation of autophagosomal vacuoles (autophagosomes). Plays a role in mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. Whereas LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation. Promotes primary ciliogenesis by removing OFD1 from centriolar satellites via the autophagic pathway.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0028R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0028R-CY3
Lokale Artikelnummer::
BOSSBS-0028R-CY3
Beschreibung:
The protein encoded by this gene is a serine-threonine kinase, belonging to the glycogen synthase kinase subfamily. It is involved in energy metabolism, neuronal cell development, and body pattern formation. Polymorphisms in this gene have been implicated in modifying risk of Parkinson disease, and studies in mice show that overexpression of this gene may be relevant to the pathogenesis of Alzheimer disease. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Sep 2009]
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6094R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6094R
Lokale Artikelnummer::
BOSSBS-6094R
Beschreibung:
RIN1 is a Ras effector protein which can affect Ras signaling in a variety of ways. It enhances signaling from ABL1 and ABL2 whcih are involved in regulation of cytoskeletal remodeling. It may function as a guanine nucleotide exchange factor in activation of Rab5a. Rin1 also competes with RAF1 for binding of the activated form of Ras. It may play a role inhibiting the modulation of neuronal plasticity in formation of aversive memory, and has been implicated as a tumor supressor gene in breast cancer.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4878R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4878R-A750
Lokale Artikelnummer::
BOSSBS-4878R-A750
Beschreibung:
The complement factor C3 consists of an alpha and a beta chain. C3 is a central factor in the complement cascade. It is central to the alternative pathway that leads to the C3 convertase C3bBb. The classical mannose binding lectin activation pathway leads to the C3 convertase C4b2a. These convertases cleave C3 resulting in C3a and C3b. Further degradation leads to the formation of the alpha chain products C3d, C3g and C3c. C3 is an acute phase protein that is produced by a wide range of tissues, including renal epithelial cells and hepatocytes.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4878R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4878R-A680
Lokale Artikelnummer::
BOSSBS-4878R-A680
Beschreibung:
The complement factor C3 consists of an alpha and a beta chain. C3 is a central factor in the complement cascade. It is central to the alternative pathway that leads to the C3 convertase C3bBb. The classical mannose binding lectin activation pathway leads to the C3 convertase C4b2a. These convertases cleave C3 resulting in C3a and C3b. Further degradation leads to the formation of the alpha chain products C3d, C3g and C3c. C3 is an acute phase protein that is produced by a wide range of tissues, including renal epithelial cells and hepatocytes.
VE:
1 * 100 µl
Lieferant:
Thermo Scientific
Beschreibung:
Natriumethanolat 21% in Ethanol, rein
Artikel-Nr:
(BOSSBS-4081R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4081R
Lokale Artikelnummer::
BOSSBS-4081R
Beschreibung:
This gene encodes a serine/threonine protein kinase belonging to the LATS tumor suppressor family. The protein localizes to centrosomes during interphase, and early and late metaphase. It interacts with the centrosomal proteins aurora-A and ajuba and is required for accumulation of gamma-tubulin and spindle formation at the onset of mitosis. It also interacts with a negative regulator of p53 and may function in a positive feedback loop with p53 that responds to cytoskeleton damage. Additionally, it can function as a co-repressor of androgen-responsive gene expression. [provided by RefSeq].
VE:
1 * 100 µl
Lieferant:
Merck
Beschreibung:
Bio-Based Ethanol
Instead of synthetic ethanol, we use bioethanol produced from grain or sugar cane. High quality, affordability, and ready availability make our bioethanol an obvious choice for a sustainable future.
Lieferant:
Merck
Beschreibung:
Bio-Based Ethanol
Instead of synthetic ethanol, we use bioethanol produced from grain or sugar cane. High quality, affordability, and ready availability make our bioethanol an obvious choice for a sustainable future.
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Dieses Produkt kann nur an eine Lieferadresse versandt werden die über die entsprechende Lizenzen verfügt. Für weitere Hilfe bitte kontaktieren Sie Ihr VWR Vertriebszentrum.
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