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(4-Isopropylphenoxy)acetyl+chloride
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(4-Isopropylphenoxy)acetyl+chloride
Artikel-Nr:
(BOSSBS-6981R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6981R-CY3
Lokale Artikelnummer::
BOSSBS-6981R-CY3
Beschreibung:
Mediates the exchange of chloride ions against protons. Functions as antiporter and contributes to the acidification of the endosome and synaptic vesicle lumen, and may thereby affect vesicle trafficking and exocytosis. May play an important role in neuronal cell function through regulation of membrane excitability by protein kinase C. It could help neuronal cells to establish short-term memory.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6981R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6981R-A488
Lokale Artikelnummer::
BOSSBS-6981R-A488
Beschreibung:
Mediates the exchange of chloride ions against protons. Functions as antiporter and contributes to the acidification of the endosome and synaptic vesicle lumen, and may thereby affect vesicle trafficking and exocytosis. May play an important role in neuronal cell function through regulation of membrane excitability by protein kinase C. It could help neuronal cells to establish short-term memory.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3604R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3604R-A750
Lokale Artikelnummer::
BOSSBS-3604R-A750
Beschreibung:
WNK1 controls sodium and chloride ion transport by inhibiting the activity of WNK4, potentially by either phosphorylating the kinase or via an interaction between WNK4 and the autoinhibitory domain of WNK1. WNK4 regulates the activity of the thiazide sensitive Na/Cl cotransporter, SLC12A3, by phosphorylation. WNK1 may also play a role in actin cytoskeletal reorganisation.
VE:
1 * 100 µl
Artikel-Nr:
(USBI033951-BIOTIN)
Lieferant:
US Biological
Hersteller-Artikelnummer::
033951-BIOTIN
Lokale Artikelnummer::
USBI033951-BIOTIN
Beschreibung:
Anti-CLCN5 Rabbit Polyclonal Antibody (Biotin)
VE:
1 * 200 µl
Artikel-Nr:
(BOSSBS-3604R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3604R-A350
Lokale Artikelnummer::
BOSSBS-3604R-A350
Beschreibung:
WNK1 controls sodium and chloride ion transport by inhibiting the activity of WNK4, potentially by either phosphorylating the kinase or via an interaction between WNK4 and the autoinhibitory domain of WNK1. WNK4 regulates the activity of the thiazide sensitive Na/Cl cotransporter, SLC12A3, by phosphorylation. WNK1 may also play a role in actin cytoskeletal reorganization.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6981R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6981R-A750
Lokale Artikelnummer::
BOSSBS-6981R-A750
Beschreibung:
Mediates the exchange of chloride ions against protons. Functions as antiporter and contributes to the acidification of the endosome and synaptic vesicle lumen, and may thereby affect vesicle trafficking and exocytosis. May play an important role in neuronal cell function through regulation of membrane excitability by protein kinase C. It could help neuronal cells to establish short-term memory.
VE:
1 * 100 µl
Artikel-Nr:
(PRSI79-481)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
79-481
Lokale Artikelnummer::
PRSI79-481
Beschreibung:
Transcription factor that can activate or repress transcription in response to physiological and pathological stimuli. Binds with high affinity to GC-rich motifs and regulates the expression of a large number of genes involved in a variety of processes such as cell growth, apoptosis, differentiation and immune responses. Highly regulated by post-translational modifications (phosphorylations, sumoylation, proteolytic cleavage, glycosylation and acetylation). Binds also the PDGFR-alpha G-box promoter. May have a role in modulating the cellular response to DNA damage. Implicated in chromatin remodeling. Plays a role in the recruitment of SMARCA4/BRG1 on the c-FOS promoter. Plays an essential role in the regulation of FE65 gene expression.
VE:
1 * 100 µG
Artikel-Nr:
(BOSSBS-12124R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12124R-A750
Lokale Artikelnummer::
BOSSBS-12124R-A750
Beschreibung:
The GAT1 gene family includes sodium- and chloride-dependent plasma membrane transporters for neurotransmitters, metabolites and osmolites, which couple substrate flux to transmembrane electrochemical gradients. PROT (Sodium-dependent proline transporter), also known as Solute carrier family 6 member 7, is a 636 amino acid multi-pass membrane protein that is a GAT1 family member specifically expressed in regions of the brain. PROT terminates the action of proline by its high affinity sodium/chloride-dependent reuptake into pre-synaptic terminals. Enriched in glutamatergic synaptic terminals, it is likely that PROT plays an important role in excitatory events of neurotransmission. PROT-mediated proline uptake is inhibited by compounds such as benztropine, LP-403812 and Des-Tyr-Leu-enkephalin (GGFL). These inhibitors of proline uptake may lead to the development of therapeutic agents for certain neurologic disorders.
VE:
1 * 100 µl
Artikel-Nr:
(PRSI25-060)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
25-060
Lokale Artikelnummer::
PRSI25-060
Beschreibung:
RUVBL1 possesses single-stranded DNA-stimulated ATPase and ATP-dependent DNA helicase (3' to 5') activity. It is the component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex ATPase and helicase activities seem to be, at least in part, contributed by the association of RUVBL1 and RUVBL2 with EP400. NuA4 may also play a direct role in DNA repair when recruited to sites of DNA damage. RUVBL1 plays an essential role in oncogenic transformation by MYC and also modulates transcriptional activation by the LEF1/TCF1-CTNNB1 complex.
VE:
1 * 50 µG
Artikel-Nr:
(BOSSBS-3604R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3604R-CY5.5
Lokale Artikelnummer::
BOSSBS-3604R-CY5.5
Beschreibung:
WNK1 controls sodium and chloride ion transport by inhibiting the activity of WNK4, potentially by either phosphorylating the kinase or via an interaction between WNK4 and the autoinhibitory domain of WNK1. WNK4 regulates the activity of the thiazide sensitive Na/Cl cotransporter, SLC12A3, by phosphorylation. WNK1 may also play a role in actin cytoskeletal reorganization.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1247R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1247R-CY3
Lokale Artikelnummer::
BOSSBS-1247R-CY3
Beschreibung:
G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling activates a phosphatidylinositol-calcium second messenger system and generates a calcium-activated chloride current. Plays an important role in the regulation of synaptic plasticity and the modulation of the neural network activity (By similarity).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3604R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3604R-A680
Lokale Artikelnummer::
BOSSBS-3604R-A680
Beschreibung:
WNK1 controls sodium and chloride ion transport by inhibiting the activity of WNK4, potentially by either phosphorylating the kinase or via an interaction between WNK4 and the autoinhibitory domain of WNK1. WNK4 regulates the activity of the thiazide sensitive Na/Cl cotransporter, SLC12A3, by phosphorylation. WNK1 may also play a role in actin cytoskeletal reorganisation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3766R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3766R-A350
Lokale Artikelnummer::
BOSSBS-3766R-A350
Beschreibung:
Component of the heteropentameric receptor for GABA, the major inhibitory neurotransmitter in the vertebrate brain. Functions also as histamine receptor and mediates cellular responses to histamine. Functions as receptor for diazepines and various anesthetics, such as pentobarbital; these are bound at a separate allosteric effector binding site. Functions as ligand-gated chloride channel (By similarity).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1232R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1232R-A488
Lokale Artikelnummer::
BOSSBS-1232R-A488
Beschreibung:
Component of the heteropentameric receptor for GABA, the major inhibitory neurotransmitter in the vertebrate brain. Functions also as histamine receptor and mediates cellular responses to histamine. Functions as receptor for diazepines and various anesthetics, such as pentobarbital; these are bound at a separate allosteric effector binding site. Functions as ligand-gated chloride channel (By similarity).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3766R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3766R-FITC
Lokale Artikelnummer::
BOSSBS-3766R-FITC
Beschreibung:
Component of the heteropentameric receptor for GABA, the major inhibitory neurotransmitter in the vertebrate brain. Functions also as histamine receptor and mediates cellular responses to histamine. Functions as receptor for diazepines and various anesthetics, such as pentobarbital; these are bound at a separate allosteric effector binding site. Functions as ligand-gated chloride channel (By similarity).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11952R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11952R-CY3
Lokale Artikelnummer::
BOSSBS-11952R-CY3
Beschreibung:
The four isoforms of potassium/chloride co-transport channels (KCC) belong to a superfamily of cation-chloride co-transporters involved in cell volume maintenance. Nitric oxide (NO) donors activate KCCs, while inhibitors of the cGMP pathway prevent NO donor activation. The ubiquitously expressed KCC1 contains 12 transmembrane domains with both cytoplasmic N and C terminal domains. KCC2 expression is limited to neuronal tissues by a restrictive element similar to the neuronal-restrictive silencing factor. In neurons, KCC2 expression is correlated with an inhibitory response to GABA, while the absence of KCC2 is necessary for an unusual excitatory response to GABA. Alterations of KCC2 expression in the inferior colliculus of rat brain may be related to seizure susceptibility. Conversely, KCC3 is not suspected to play a major role in epilepsy. The two splice variants of KCC3, KCC3a and KCC3b, are predominantly expressed in brain and kidney, respectively, while KCC4 is expressed in muscle, brain, lung, heart and kidney.
VE:
1 * 100 µl
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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