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(4-Isopropylphenoxy)acetyl+chloride
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(4-Isopropylphenoxy)acetyl+chloride
Artikel-Nr:
(COBBFA-1321-1G)
Lieferant:
COMBI-BLOCKS
Hersteller-Artikelnummer::
FA-1321-1G
Lokale Artikelnummer::
COBBFA-1321-1G
Beschreibung:
4-Acetyl-3-fluorphenylboronsäure
VE:
1 * 1 g
 This is a MarketSource item. Additional charges may apply
Artikel-Nr:
(BOSSBS-7618R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7618R-A750
Lokale Artikelnummer::
BOSSBS-7618R-A750
Beschreibung:
NOC2L is a transcriptional corepressor with inhibitor of histone acetyltransferase (INHAT) activity. NOC2L or NIR (Novel INHAT Repressor) is ubiquitously expressed throughout embryonic development and adulthood. It is a potent transcriptional corepressor that is not blocked by histone deacetylase inhibitors and is capable of silencing both basal and activator-driven transcription. NOC2L directly binds to nucleosomes and core histones and prevents acetylation by histone acetyltransferases, thus acting as a bona fide INHAT.
VE:
1 * 100 µl
Lieferant:
COMBI-BLOCKS
Beschreibung:
5-Acetyl-2-methoxypyridin
Lieferant:
CHEMPUR
Beschreibung:
3-Acetyl-2-brompyridin
Artikel-Nr:
(BOSSBS-7618R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7618R-FITC
Lokale Artikelnummer::
BOSSBS-7618R-FITC
Beschreibung:
NOC2L is a transcriptional corepressor with inhibitor of histone acetyltransferase (INHAT) activity. NOC2L or NIR (Novel INHAT Repressor) is ubiquitously expressed throughout embryonic development and adulthood. It is a potent transcriptional corepressor that is not blocked by histone deacetylase inhibitors and is capable of silencing both basal and activator-driven transcription. NOC2L directly binds to nucleosomes and core histones and prevents acetylation by histone acetyltransferases, thus acting as a bona fide INHAT.
VE:
1 * 100 µl
Artikel-Nr:
(ENAMEN30009787.1G)
Lieferant:
SIA ENAMINE
Hersteller-Artikelnummer::
EN30009787.1G
Lokale Artikelnummer::
ENAMEN30009787.1G
Beschreibung:
2-Acetyl-5-brombenzofuran
VE:
1 * 1 g
This is a MarketSource item. Additional charges may apply
Artikel-Nr:
(BOSSBS-10228R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-10228R-A750
Lokale Artikelnummer::
BOSSBS-10228R-A750
Beschreibung:
The protein encoded by this gene can hydrolyse substrates such as AMP-morpholidate, AMP-N-alanine methyl ester, AMP-alpha-acetyl lysine methyl ester, and AMP-NH2. The encoded protein interacts with these substrates via a histidine triad motif, which is part of the loop that binds to the substrate. This gene has been found to be a tumour suppressing gene. Several transcript variants, but only one of them protein-coding, have been found for this gene.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3581R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3581R-A647
Lokale Artikelnummer::
BOSSBS-3581R-A647
Beschreibung:
Nuclear corepressor for KRAB domain-containing zinc finger proteins (KRAB-ZFPs). Mediates gene silencing by recruiting CHD3, a subunit of the nucleosome remodeling and deacetylation (NuRD) complex, and SETDB1 (which specifically methylates histone H3 at 'Lys-9' (H3K9me)) to the promoter regions of KRAB target genes. Enhances transcriptional repression by coordinating the increase in H3K9me, the decrease in histone H3 'Lys-9 and 'Lys-14' acetylation (H3K9ac and H3K14ac, respectively) and the disposition of HP1 proteins to silence gene expression. Recruitment of SETDB1 induces heterochromatinization. May play a role as a coactivator for CEBPB and NR3C1 in the transcriptional activation of ORM1. Also corepressor for ERBB4. Inhibits E2F1 activity by stimulating E2F1-HDAC1 complex formation and inhibiting E2F1 acetylation. May serve as a partial backup to prevent E2F1-mediated apoptosis in the absence of RB1. Important regulator of CDKN1A/p21(CIP1). Has E3 SUMO-protein ligase activity toward itself via its PHD-type zinc finger. Also specifically sumoylates IRF7, thereby inhibiting its transactivation activity. Ubiquitinates p53/TP53 leading to its proteosomal degradation; the function is enhanced by MAGEC2 and MAGEA2, and possibly MAGEA3 and MAGEA6. Mediates the nuclear localization of KOX1, ZNF268 and ZNF300 transcription factors.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13452R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13452R-HRP
Lokale Artikelnummer::
BOSSBS-13452R-HRP
Beschreibung:
The large binding pocket can accommodate several single chain phospholipids and fatty acids, GM2A also exhibits some calcium-independent phospholipase activity (By similarity). Binds gangliosides and stimulates ganglioside GM2 degradation. It stimulates only the breakdown of ganglioside GM2 and glycolipid GA2 by beta-hexosaminidase A. It extracts single GM2 molecules from membranes and presents them in soluble form to beta-hexosaminidase A for cleavage of N-acetyl-D-galactosamine and conversion to GM3.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6383R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6383R
Lokale Artikelnummer::
BOSSBS-6383R
Beschreibung:
The minichromosome maintenance protein 3 (MCM3) is one of the MCM proteins essential for the initiation of DNA replication. The protein encoded by this gene is a MCM3 binding protein. It was reported to have phosphorylation-dependent DNA-primase activity, which was up-regulated in antigen immunization induced germinal center. This protein was demonstrated to be an acetyltransferase that acetylates MCM3 and plays a role in DNA replication. The mutagenesis of a nuclear localization signal of MCM3 affects the binding of this protein with MCM3, suggesting that this protein may also facilitate MCM3 nuclear localization.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0518R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0518R-A488
Lokale Artikelnummer::
BOSSBS-0518R-A488
Beschreibung:
Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA-3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA-3'). In the nucleus, contributes to global transcription and the DNA damage response, in addition to specific transcriptional activities that are related to cell development, proliferation and death. In the cytoplasm, interacts with and perturbs HK1- and VDAC1-containing complexes at the mitochondrial outer membrane, thereby impairing mitochondrial membrane potential, inducing mitochondrial leakage and promoting cell death. The phosphorylated form (mediated by ATM) plays a role in the DNA damage response and is involved in the ionizing radiation (IR)-induced S phase checkpoint control and in the recruitment of the MRN complex into the IR-induced foci (IRIF). Exhibits histone acetyltransferase (HAT) activity which specifically acetylates histones H2B and H4 in vitro. In concert with CUL3 and RBX1, promotes the degradation of KAT5 thereby attenuating its ability to acetylate and activate ATM. Can elicit oncogenic or tumor suppressor activities depending on the tissue or cell type.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0518R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0518R-CY5
Lokale Artikelnummer::
BOSSBS-0518R-CY5
Beschreibung:
Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA-3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA-3'). In the nucleus, contributes to global transcription and the DNA damage response, in addition to specific transcriptional activities that are related to cell development, proliferation and death. In the cytoplasm, interacts with and perturbs HK1- and VDAC1-containing complexes at the mitochondrial outer membrane, thereby impairing mitochondrial membrane potential, inducing mitochondrial leakage and promoting cell death. The phosphorylated form (mediated by ATM) plays a role in the DNA damage response and is involved in the ionizing radiation (IR)-induced S phase checkpoint control and in the recruitment of the MRN complex into the IR-induced foci (IRIF). Exhibits histone acetyltransferase (HAT) activity which specifically acetylates histones H2B and H4 in vitro. In concert with CUL3 and RBX1, promotes the degradation of KAT5 thereby attenuating its ability to acetylate and activate ATM. Can elicit oncogenic or tumor suppressor activities depending on the tissue or cell type.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11018R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11018R
Lokale Artikelnummer::
BOSSBS-11018R
Beschreibung:
This gene encodes a Golgi protein which is a member of the polypeptide N-acetylgalactosaminyltransferase (ppGalNAc-Ts) protein family. These enzymes catalyze the transfer of N-acetyl-D-galactosamine (GalNAc) to the hydroxyl groups on serines and threonines in target peptides. The encoded protein has been shown to transfer GalNAc to large proteins like mucins. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011].
VE:
1 * 100 µl
Artikel-Nr:
(38800-25MG)
Lieferant:
Sigma-Aldrich
Hersteller-Artikelnummer::
38800-25MG
Lokale Artikelnummer::
SUPL38800-25MG
Beschreibung:
Malachitgrün-Chlorid, Supelco®
VE:
1 * 25 mg
Artikel-Nr:
(BOSSBS-7618R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7618R-CY3
Lokale Artikelnummer::
BOSSBS-7618R-CY3
Beschreibung:
NOC2L is a transcriptional corepressor with inhibitor of histone acetyltransferase (INHAT) activity. NOC2L or NIR (Novel INHAT Repressor) is ubiquitously expressed throughout embryonic development and adulthood. It is a potent transcriptional corepressor that is not blocked by histone deacetylase inhibitors and is capable of silencing both basal and activator-driven transcription. NOC2L directly binds to nucleosomes and core histones and prevents acetylation by histone acetyltransferases, thus acting as a bona fide INHAT.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-10492R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-10492R
Lokale Artikelnummer::
BOSSBS-10492R
Beschreibung:
This gene encodes a tumor suppressor protein that contains a PHD-finger, which is a common motif in proteins involved in chromatin remodeling. This protein can bind TP53 and EP300/p300, a component of the histone acetyl transferase complex, suggesting its involvement in the TP53-dependent regulatory pathway. Multiple alternatively spliced transcript variants have been observed that encode distinct proteins. [provided by RefSeq, Jul 2008].
VE:
1 * 100 µl
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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