2\',4\'-Difluorbiphenyl-4-carbonsäure
Artikel-Nr:
(BOSSBS-3814R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3814R-CY5
Lokale Artikelnummer::
BOSSBS-3814R-CY5
Beschreibung:
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E1 ubiquitin-activating enzyme family. The encoded enzyme is a retinoid target that triggers promyelocytic leukemia (PML)/retinoic acid receptor alpha (RARalpha) degradation and apoptosis in acute promyelocytic leukemia, where it is involved in the conjugation of the ubiquitin-like interferon-stimulated gene 15 protein. [provided by RefSeq, Jul 2008].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13387R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13387R-CY3
Lokale Artikelnummer::
BOSSBS-13387R-CY3
Beschreibung:
Glucose Oxidase is a dimeric enzyme that binds to β-D-glucose and aids in its oxidation into D-glucono-1,5-lactone which then hydrolyzes to gluconic acid. Flavin adenine dinucleotide (FAD) is a cofactor to Glucose Oxidase that acts as the initial electron acceptor and is required for this oxidation to occur. Glucose Oxidase is a natural preservative found in honey, where it reduces atmospheric oxygen into hydrogen peroxide which acts as an antibacterial barrier. Glucose Oxidase is also commonly used in biosensors in which it conveys levels of glucose by keeping track of the number of electrons passed through the enzyme. In this application, Glucose Oxidase is connected to an electrode and the resulting charge is measured.
VE:
1 * 100 µl
Artikel-Nr:
(TEST0560.1109)
Lieferant:
Testo
Hersteller-Artikelnummer::
0560.1109
Lokale Artikelnummer::
TEST0560.1109
Beschreibung:
Das Mini-Oberflächenthermometer hat einen sehr großen Anwendungsbereich und lässt sich für Oberflächentemperaturmessungen verschiedenster Art nutzen (Temperaturkontrollen im Heizungsbau, Sanitärbereich oder in der Klima-/Kälte und Lüftungstechnik).
VE:
1 * 1 ST
Artikel-Nr:
(BOSSBS-3814R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3814R-HRP
Lokale Artikelnummer::
BOSSBS-3814R-HRP
Beschreibung:
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E1 ubiquitin-activating enzyme family. The encoded enzyme is a retinoid target that triggers promyelocytic leukemia (PML)/retinoic acid receptor alpha (RARalpha) degradation and apoptosis in acute promyelocytic leukemia, where it is involved in the conjugation of the ubiquitin-like interferon-stimulated gene 15 protein. [provided by RefSeq, Jul 2008].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13387R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13387R-A647
Lokale Artikelnummer::
BOSSBS-13387R-A647
Beschreibung:
Glucose Oxidase is a dimeric enzyme that binds to β-D-glucose and aids in its oxidation into D-glucono-1,5-lactone which then hydrolyzes to gluconic acid. Flavin adenine dinucleotide (FAD) is a cofactor to Glucose Oxidase that acts as the initial electron acceptor and is required for this oxidation to occur. Glucose Oxidase is a natural preservative found in honey, where it reduces atmospheric oxygen into hydrogen peroxide which acts as an antibacterial barrier. Glucose Oxidase is also commonly used in biosensors in which it conveys levels of glucose by keeping track of the number of electrons passed through the enzyme. In this application, Glucose Oxidase is connected to an electrode and the resulting charge is measured.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9350R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9350R-CY3
Lokale Artikelnummer::
BOSSBS-9350R-CY3
Beschreibung:
Ubiquitin-dependent proteolysis mediates selective destruction of various cell cycle regulators, transcription factors and tumor suppressors. In eukaryotic cells, selective breakdown of cellular proteins is ensured by their ubiquitination and subsequent degradation by the 26S proteasome. At specific stages of development, embryo- and tissue-specific components of the 26S proteasome form, facilitating proteolysis. 20S Proteasome ?, also designated macropain subunit C2 or PROS-30, is a prosomal protein involved in a non-lysosomal ATP/ubiquitin-dependent proteolytic pathway. The entire proteasome is composed of at least 15 non-identical subunits which form a highly-ordered ring-shaped structure.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9350R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9350R-CY7
Lokale Artikelnummer::
BOSSBS-9350R-CY7
Beschreibung:
Ubiquitin-dependent proteolysis mediates selective destruction of various cell cycle regulators, transcription factors and tumor suppressors. In eukaryotic cells, selective breakdown of cellular proteins is ensured by their ubiquitination and subsequent degradation by the 26S proteasome. At specific stages of development, embryo- and tissue-specific components of the 26S proteasome form, facilitating proteolysis. 20S Proteasome ?, also designated macropain subunit C2 or PROS-30, is a prosomal protein involved in a non-lysosomal ATP/ubiquitin-dependent proteolytic pathway. The entire proteasome is composed of at least 15 non-identical subunits which form a highly-ordered ring-shaped structure.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9988R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9988R-A680
Lokale Artikelnummer::
BOSSBS-9988R-A680
Beschreibung:
The smallest of the human chromosomes, 21 makes up about 1.5% of the human genome. Chromosome 21 contains nearly 300 genes and 47 million base pairs. Down syndrome, also known as trisomy 21, is the disease most commonly associated with chromosome 21. Alzheimer's disease, Jervell and Lange-Nielsen syndrome and amyotrophic lateral sclerosis are also associated with chromosome 21. Translocations are found to occur between chromosome 21 and 8, and chromosome 21 and 12, in certain leukaemias. C2CD2 is an 696 amino acid protein that is secreted. The C2CD2 gene product has been provisionally designated C2CD2 pending further characterisation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11785R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11785R-A488
Lokale Artikelnummer::
BOSSBS-11785R-A488
Beschreibung:
Maspardin is a 308 amino acid cytoplasmic protein that is widely expressed. Belonging to the AB hydrolase superfamily, Maspardin colocalizes with CD4 on endosomal/trans-Golgi network. It is thought that Maspardin may act as a negative regulatory factor in CD4-dependent T-cell activation. Defects in the gene encoding Maspardin are the result of hereditary spastic paraplegia autosomal recessive type 21 (also designated Mast syndrome), an autosomal recessive neurodegenerative disorder characterized by a slow, gradual, progressive weakness and spasticity of the lower limbs. The gene encoding Maspardin is encoded by human chromosome 15, which houses over 700 genes and comprises nearly 3% of the human genome.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-15126R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-15126R-A350
Lokale Artikelnummer::
BOSSBS-15126R-A350
Beschreibung:
The smallest of the human chromosomes, 21 makes up about 1.5% of the human genome. Chromosome 21 contains nearly 300 genes and 47 million base pairs. Down syndrome, also known as trisomy 21, is the disease most commonly associated with chromosome 21. Alzheimer's disease, Jervell and Lange-Nielsen syndrome and amyotrophic lateral sclerosis are also associated with chromosome 21. Translocations are found to occur between chromosome 21 and 8, and chromosome 21 and 12, in certain leukemias. C21orf59, also known as C21orf48, is a 290 amino acid protein and its gene product has been provisionally designated C21orf59 pending further characterization.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9512R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9512R-A647
Lokale Artikelnummer::
BOSSBS-9512R-A647
Beschreibung:
Protein S (PROS) is a vitamin K-dependent plasma protein that inhibits blood clotting by serving as a cofactor for activated protein C (APC) and facilitates clearance of early apoptotic cells. In the plasma, circulating Protein S becomes inactive upon complexing with C4b-binding protein (C4BP); 60-70% of Protein S circulates in complex with C4BP. Calcium-dependent association of C4BP-Protein S with apoptotic cells influences the regulation of complement activation. Protein S has APC-independent anticoagulant activity through direct inhibition of prothrombin activation via interactions with Factor X A, Factor V A and phospholipids. Autosomal dominant Protein S deficiency (levels 15 to 37% of normal) correlates with severe recurrent venous thrombosis.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9512R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9512R-A680
Lokale Artikelnummer::
BOSSBS-9512R-A680
Beschreibung:
Protein S (PROS) is a vitamin K-dependent plasma protein that inhibits blood clotting by serving as a cofactor for activated protein C (APC) and facilitates clearance of early apoptotic cells. In the plasma, circulating Protein S becomes inactive upon complexing with C4b-binding protein (C4BP); 60 to 70% of Protein S circulates in complex with C4BP. Calcium-dependent association of C4BP-Protein S with apoptotic cells influences the regulation of complement activation. Protein S has APC-independent anticoagulant activity through direct inhibition of prothrombin activation via interactions with Factor X A, Factor V A and phospholipids. Autosomal dominant Protein S deficiency (levels 15 to 37% of normal) correlates with severe recurrent venous thrombosis.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12406R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12406R-A750
Lokale Artikelnummer::
BOSSBS-12406R-A750
Beschreibung:
SNX2 and SNX4 share a high degree of amino acid similarity with SNX1, as they all contain a characteristic phox homology (PX) domain (4). These proteins are all partially associated with cellular membranes, and they, likewise, associate with EGF, PDGF and insulin receptor tyrosine kinases (2). These nexins are widely expressed and yet have various tissue distribution patterns. Additionally, the sorting nexins can associate with each other and with a variety of other cellular proteins, suggesting that they exist as part of multisubunit complexes (1,5). The related protein, SNX3, comprises a distinct subgroup of nexins that share less sequence similarity outside of the PX domain and have dramatically different binding affinities for the tyrosine kinase receptors (2,6).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9350R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9350R-A750
Lokale Artikelnummer::
BOSSBS-9350R-A750
Beschreibung:
Ubiquitin-dependent proteolysis mediates selective destruction of various cell cycle regulators, transcription factors and tumor suppressors. In eukaryotic cells, selective breakdown of cellular proteins is ensured by their ubiquitination and subsequent degradation by the 26S proteasome. At specific stages of development, embryo- and tissue-specific components of the 26S proteasome form, facilitating proteolysis. 20S Proteasome ?, also designated macropain subunit C2 or PROS-30, is a prosomal protein involved in a non-lysosomal ATP/ubiquitin-dependent proteolytic pathway. The entire proteasome is composed of at least 15 non-identical subunits which form a highly-ordered ring-shaped structure.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9350R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9350R-A488
Lokale Artikelnummer::
BOSSBS-9350R-A488
Beschreibung:
Ubiquitin-dependent proteolysis mediates selective destruction of various cell cycle regulators, transcription factors and tumor suppressors. In eukaryotic cells, selective breakdown of cellular proteins is ensured by their ubiquitination and subsequent degradation by the 26S proteasome. At specific stages of development, embryo- and tissue-specific components of the 26S proteasome form, facilitating proteolysis. 20S Proteasome ?, also designated macropain subunit C2 or PROS-30, is a prosomal protein involved in a non-lysosomal ATP/ubiquitin-dependent proteolytic pathway. The entire proteasome is composed of at least 15 non-identical subunits which form a highly-ordered ring-shaped structure.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9512R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9512R-A750
Lokale Artikelnummer::
BOSSBS-9512R-A750
Beschreibung:
Protein S (PROS) is a vitamin K-dependent plasma protein that inhibits blood clotting by serving as a cofactor for activated protein C (APC) and facilitates clearance of early apoptotic cells. In the plasma, circulating Protein S becomes inactive upon complexing with C4b-binding protein (C4BP); 60 to 70% of Protein S circulates in complex with C4BP. Calcium-dependent association of C4BP-Protein S with apoptotic cells influences the regulation of complement activation. Protein S has APC-independent anticoagulant activity through direct inhibition of prothrombin activation via interactions with Factor X A, Factor V A and phospholipids. Autosomal dominant Protein S deficiency (levels 15 to 37% of normal) correlates with severe recurrent venous thrombosis.
VE:
1 * 100 µl
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