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[4-(1H-Pyrazol-1-yl)phenyl]boronic+acid
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[4-(1H-Pyrazol-1-yl)phenyl]boronic+acid
Artikel-Nr:
(BOSSBS-5523R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5523R-HRP
Lokale Artikelnummer::
BOSSBS-5523R-HRP
Beschreibung:
Nudel is important for normal cortical development. It is invovled in microtubule organization, nuclear translocation, and neuronal positioning in concert with various other factors (including Lis1, Pafah1b1, Pahfah1b2, dynein, dynorphin A and cdk5). Western blot analysis of mouse tissues shows abundant expression of Nudel in brain and testis, and much lower expression in heart, liver, kidney, and skeletal muscle. In fractionated rat brain, Nudel and Lis1 are both found in fractions enriched for postsynaptic density proteins. Immunostaining of embryonic day 18 mouse brain sections revealed staining of migrating neurons and thalamocortical axons of the intermediate zone of the developing cerebral cortex, as well as several other developing brain regions. The deduced protein contains 345 amino acids and has a calculated molecular mass of 38.4 kDa. It has a coiled coil motif (residues 19 to 201), followed by several potential phosphorylation sites for casein kinase II, protein kinase C or CDK5. Nudel shares about 50% identity with mouse and human NUDE proteins.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5522R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5522R-A350
Lokale Artikelnummer::
BOSSBS-5522R-A350
Beschreibung:
Nudel is important for normal cortical development. It is invovled in microtubule organization, nuclear translocation, and neuronal positioning in concert with various other factors (including Lis1, Pafah1b1, Pahfah1b2, dynein, dynorphin A and cdk5). Western blot analysis of mouse tissues shows abundant expression of Nudel in brain and testis, and much lower expression in heart, liver, kidney, and skeletal muscle. In fractionated rat brain, Nudel and Lis1 are both found in fractions enriched for postsynaptic density proteins. Immunostaining of embryonic day 18 mouse brain sections revealed staining of migrating neurons and thalamocortical axons of the intermediate zone of the developing cerebral cortex, as well as several other developing brain regions. The deduced protein contains 345 amino acids and has a calculated molecular mass of 38.4 kDa. It has a coiled coil motif (residues 19 to 201), followed by several potential phosphorylation sites for casein kinase II, protein kinase C or CDK5. Nudel shares about 50% identity with mouse and human NUDE proteins.
VE:
1 * 100 µl
Lieferant:
HAMMACHER KARL
Beschreibung:
Edelstahl 18/10, antimagnetisch. Zur leichten und sicheren Handhabung von Tiegeln verschiedenster Materialien.
Artikel-Nr:
(BRND470045)
Lieferant:
Brand
Hersteller-Artikelnummer::
470045
Lokale Artikelnummer::
BRND470045
Beschreibung:
Diese Deckgläser sind aus reinweißem Klarglas und bieten eine gute chemische Beständigkeit.
VE:
1 * 2.000 ST
Artikel-Nr:
(BOSSBS-5973R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5973R-CY5
Lokale Artikelnummer::
BOSSBS-5973R-CY5
Beschreibung:
NAD-dependent protein deacetylase that specifically mediates deacetylation of histone H3 at 'Lys-18' (H3K18Ac). In contrast to other histone deacetylases, displays selectivity for a single histone mark, H3K18Ac, directly linked to control of gene expression. H3K18Ac is mainly present around the transcription start site of genes and has been linked to activation of nuclear hormone receptors. SIRT7 thereby acts as a transcription repressor. Moreover, H3K18 hypoacetylation has been reported as a marker of malignancy in various cancers and seems to maintain the transformed phenotype of cancer cells. These data suggest that SIRT7 may play a key role in oncogenic transformation by suppresses expression of tumor suppressor genes by locus-specific deacetylation of H3K18Ac at promoter regions. Also required to restore the transcription of ribosomal RNA (rRNA) at the exit from mitosis: promotes the association of RNA polymerase I with the rDNA promoter region and coding region. Stimulates transcription activity of the RNA polymerase I complex. May also deacetylate p53/TP53 and promotes cell survival, however such data need additional confirmation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5973R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5973R-CY5.5
Lokale Artikelnummer::
BOSSBS-5973R-CY5.5
Beschreibung:
NAD-dependent protein deacetylase that specifically mediates deacetylation of histone H3 at 'Lys-18' (H3K18Ac). In contrast to other histone deacetylases, displays selectivity for a single histone mark, H3K18Ac, directly linked to control of gene expression. H3K18Ac is mainly present around the transcription start site of genes and has been linked to activation of nuclear hormone receptors. SIRT7 thereby acts as a transcription repressor. Moreover, H3K18 hypoacetylation has been reported as a marker of malignancy in various cancers and seems to maintain the transformed phenotype of cancer cells. These data suggest that SIRT7 may play a key role in oncogenic transformation by suppresses expression of tumor suppressor genes by locus-specific deacetylation of H3K18Ac at promoter regions. Also required to restore the transcription of ribosomal RNA (rRNA) at the exit from mitosis: promotes the association of RNA polymerase I with the rDNA promoter region and coding region. Stimulates transcription activity of the RNA polymerase I complex. May also deacetylate p53/TP53 and promotes cell survival, however such data need additional confirmation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5973R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5973R-A680
Lokale Artikelnummer::
BOSSBS-5973R-A680
Beschreibung:
NAD-dependent protein deacetylase that specifically mediates deacetylation of histone H3 at 'Lys-18' (H3K18Ac). In contrast to other histone deacetylases, displays selectivity for a single histone mark, H3K18Ac, directly linked to control of gene expression. H3K18Ac is mainly present around the transcription start site of genes and has been linked to activation of nuclear hormone receptors. SIRT7 thereby acts as a transcription repressor. Moreover, H3K18 hypoacetylation has been reported as a marker of malignancy in various cancers and seems to maintain the transformed phenotype of cancer cells. These data suggest that SIRT7 may play a key role in oncogenic transformation by suppresses expression of tumor suppressor genes by locus-specific deacetylation of H3K18Ac at promoter regions. Also required to restore the transcription of ribosomal RNA (rRNA) at the exit from mitosis: promotes the association of RNA polymerase I with the rDNA promoter region and coding region. Stimulates transcription activity of the RNA polymerase I complex. May also deacetylate p53/TP53 and promotes cell survival, however such data need additional confirmation.
VE:
1 * 100 µl
Artikel-Nr:
(HAMMHWN100-15)
Lieferant:
HAMMACHER KARL
Hersteller-Artikelnummer::
HWN100-15
Lokale Artikelnummer::
HAMMHWN100-15
Beschreibung:
Double-ended micro spoon made of Wironit steel (stainless steel 18/12 with 18 % chrome and 10 to 12 % nickel).
VE:
1 * 1 ST
Lieferant:
BOCHEM
Beschreibung:
Edelstahl 18/10.
Lieferant:
QVF LABORTECHNIK
Beschreibung:
Made of the most corrosion resistant, red coloured material PBT.
Artikel-Nr:
(HECH41326018)
Lieferant:
GLASWARENFABRIK KARL HECHT
Hersteller-Artikelnummer::
41326018
Lokale Artikelnummer::
HECH41326018
Beschreibung:
PP, schwarz.
VE:
1 * 10 ST
Lieferant:
BOCHEM
Beschreibung:
Edelstahl 18/10, antimagnetisch. Universallöffel für eine Vielzahl von Verwendungen. Spezielle Form für leichtes und einfaches Handling.
Lieferant:
HAMMACHER KARL
Beschreibung:
Pinzetten, Präszisionspinzetten, Edelstahl 18/10, Gerade, Spitzen: Fein, 155 mm
Lieferant:
PRIMERDESIGN
Beschreibung:
Papillomviren sind eine vielfältige Gruppe von DNA-Viren, die für Infektionen der Haut und Schleimhäute des Menschen und einer Vielzahl von Tieren verantwortlich sind. Obwohl mehr als 100 unterschiedliche humane Papillomvirus(HPV)-Typen charakterisiert wurden, sind HPV 6, HPV 11, HPV-16 und HPV 18 von größter klinischer Relevanz.
Artikel-Nr:
(USBI035079-BIOTIN)
Lieferant:
US Biological
Hersteller-Artikelnummer::
035079-BIOTIN
Lokale Artikelnummer::
USBI035079-BIOTIN
Beschreibung:
Anti-ENPEP Rabbit Polyclonal Antibody (Biotin)
VE:
1 * 200 µl
Artikel-Nr:
(BOSSBS-11073R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11073R-HRP
Lokale Artikelnummer::
BOSSBS-11073R-HRP
Beschreibung:
The cadherins are a family of Ca2+-dependent adhesion molecules that function to mediate cell-cell binding events that are critical to the maintenance of cell structure and morphogenesis. EY-cadherin, also known as CDH18 (cadherin 18), CDH14 (cadherin 14), CDH24 or CDH14L, is a 790 amino acid single-pass type I membrane protein that contains five cadherin domains. One of several members of the cadherin superfamily, EY-cadherin functions as a type II classical cadherin that is expressed specifically in the central nervous system (CNS), where it plays a role in cell-cell binding events. Specifically, EY-cadherin is thought to be involved in axon guidance and outgrowth, as well as synaptic adhesion within the CNS. EY-cadherin contains a highly conserved C-terminal domain characteristic of all cadherins, but lacks the HAV cell adhesion sequence that is specific to type I cadherins. The gene encoding EY-cadherin is located within a region on chromosome five that is commonly deleted in carcinomas, implicating EY-cadherin as a potential tumor suppressor.
VE:
1 * 100 µl
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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