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Potassium+2-(trifluoromethyl)phenyltrifluoroborate
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Potassium+2-(trifluoromethyl)phenyltrifluoroborate
Artikel-Nr:
(BOSSBS-6728R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6728R-HRP
Lokale Artikelnummer::
BOSSBS-6728R-HRP
Beschreibung:
Ca2+/calmodulin dependent protein kinase type IV (CAMKIV) belongs to the serine/threonine protein kinase family, and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. This enzyme is a multifunctional serine/threonine protein kinase with limited tissue distribution, that has been implicated in transcriptional regulation in lymphocytes, neurons and male germ cells.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4593R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4593R-A680
Lokale Artikelnummer::
BOSSBS-4593R-A680
Beschreibung:
May play an essential role in local proteolysis of the extracellular matrix and in leukocyte migration. Could play a role in bone osteoclastic resorption. Cleaves KiSS1 at a Gly-|-Leu bond. Cleaves type IV and type V collagen into large C-terminal three quarter fragments and shorter N-terminal one quarter fragments. Degrades fibronectin but not laminin or Pz-peptide.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1856R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1856R-CY7
Lokale Artikelnummer::
BOSSBS-1856R-CY7
Beschreibung:
Endopeptidase that degrades various components of the extracellular matrix, such as collagen type III and fibronectin. Activates progelatinase A. Involved in the matrix remodeling of blood vessels. Isoform short cleaves fibronectin and also collagen type III, but at lower rate. It has no effect on type I, II, IV and V collagen. However, upon interaction with CSPG4, it may be involved in degradation and invasion of type I collagen by melanoma cells.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1856R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1856R-CY3
Lokale Artikelnummer::
BOSSBS-1856R-CY3
Beschreibung:
Endopeptidase that degrades various components of the extracellular matrix, such as collagen type III and fibronectin. Activates progelatinase A. Involved in the matrix remodeling of blood vessels. Isoform short cleaves fibronectin and also collagen type III, but at lower rate. It has no effect on type I, II, IV and V collagen. However, upon interaction with CSPG4, it may be involved in degradation and invasion of type I collagen by melanoma cells.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1377R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1377R-A680
Lokale Artikelnummer::
BOSSBS-1377R-A680
Beschreibung:
Matrix metalloproteinase 26 preprotein; gelatinase A; 70kD type IV collagenase; gelatinase neutrophil. Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes as well as in disease processes. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. MMP26 degrades type IV collagen, the major structural component of basement membranes. The enzyme plays a role in endometrial menstrual breakdown, regulation of vascularization and the inflammatory response.Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodelling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. MMP26, also known as Matrilysin 2, was first cloned from human fetal cells, and identified as an MMP most closely related to MMP7 (Matrilysin 1). The homology between MMP7 and MMP26 is low (only 38% identical), thus the functions are unlikely to be similar. Homology is much higher (48% identical) for the comparable region of MMP12, but MMP26 appears to have broader substrate specificity than does MMP12. MMP26, like MMP7, lacks the hemopexin domain common to the other MMPs, but contains a Propeptide domain, cysteine switch activation site, followed by a catalytic domain, and a short vestige of the hinge region. MMP26 is apparently not glycosylated, and is a secreted MMP. Tissue analysis shows MMP26 most strongly in placenta and uterus, but also in kidney cells, lung cells, lymphocytes and lung or endometrial carcinoma cells. MMP26 is proteolytically active, cleaving casein in zymograms, and gelatin, a1PI, fibrinogen, fibronectin, vitronectin, type IV collagen, and apparently activating MMP9.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0318R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0318R-CY5.5
Lokale Artikelnummer::
BOSSBS-0318R-CY5.5
Beschreibung:
PADI4 (peptidyl arginine deiminase, type IV) catalyzes the deimination of arginine residues of proteins. Down-regulates histone H3 and H4 arginine methylation, both by preventing arginine methylation by CARM1 and HRMT1L2/PRMT1 and by converting methylarginine to citrulline. subcellular location at cytoplasmic granules. Belongs to the protein arginine deiminase family. This gene may play a role in granulocyte and macrophage development leading to inflammation and immune response.
VE:
1 * 100 µl
Lieferant:
Corning
Beschreibung:
PS, coated with mouse laminin. Laminin, a major structural component of basement membranes, has many varied functions that are mediated by binding to various components of the basement membrane (for example, collagen IV) and to cell-surface receptors. Laminin-coated cell culture plates have a number of applications, including the promotion of cell adhesion, proliferation and differentiation of a variety of cell types, particularly neurons, epithelial cells, myocytes and myoblasts.
Artikel-Nr:
(20284.153)
Lieferant:
VWR Chemicals
Lokale Artikelnummer::
VWRC20284.153
Beschreibung:
trans-1,2-Diaminocyclohexan-N,N,N',N'-tetraessigsäure Monohydrat ≥99,0%
VE:
1 * 50 g
Artikel-Nr:
(USBIC2266-01T)
Lieferant:
US Biological
Hersteller-Artikelnummer::
C2266-01T
Lokale Artikelnummer::
USBIC2266-01T
Beschreibung:
Anti-FUT4 Mouse Monoclonal Antibody [clone: AHN1.1]
VE:
1 * 100 µG
Lieferant:
Biotium
Beschreibung:
Recognizes a protein of 80 kDa-90 kDa, identified as CD36 (Workshop IV; Code P-26). Its epitope maps between aa155-183. It is expressed on platelets, monocytes and macrophages, microvascular endothelial cells, erythrocyte precursors, mammary epithelial cells, and some macrophage derived dendritic cells. CD36 acts as a receptor for thrombospondin (TSP), collagen types I, IV and V, P. falciparum malaria-infected erythrocytes, and sickle erythrocytes. It also functions as a scavenger receptor, mediating macrophage uptake of oxidized low-density lipoprotein (LDL) and recognition of apoptotic polymorphonuclear leukocytes (PMN). CD36 plays a role in platelet aggregation, macrophage foam cell development, inflammation, and the tissue ischemia observed in sickle cell disease and cerebral malaria. Note that 1-4% of Japanese and East Asia population lack CD36. This MAb blocks adhesion of P. falciparum parasitized red blood cells to CD36 and strongly inhibits collagen-induced platelet aggregation.
Lieferant:
Biotium
Beschreibung:
Recognizes a protein of 80 kDa-90 kDa, identified as CD36 (Workshop IV; Code P-26). Its epitope maps between aa155-183. It is expressed on platelets, monocytes and macrophages, microvascular endothelial cells, erythrocyte precursors, mammary epithelial cells, and some macrophage derived dendritic cells. CD36 acts as a receptor for thrombospondin (TSP), collagen types I, IV and V, P. falciparum malaria-infected erythrocytes, and sickle erythrocytes. It also functions as a scavenger receptor, mediating macrophage uptake of oxidized low-density lipoprotein (LDL) and recognition of apoptotic polymorphonuclear leukocytes (PMN). CD36 plays a role in platelet aggregation, macrophage foam cell development, inflammation, and the tissue ischemia observed in sickle cell disease and cerebral malaria. Note that 1-4% of Japanese and East Asia population lack CD36. This MAb blocks adhesion of P. falciparum parasitized red blood cells to CD36 and strongly inhibits collagen-induced platelet aggregation.
Artikel-Nr:
(USBIC2277-07H)
Lieferant:
US Biological
Hersteller-Artikelnummer::
C2277-07H
Lokale Artikelnummer::
USBIC2277-07H
Beschreibung:
Anti-DPP4 Mouse Monoclonal Antibody [clone: 5E8]
VE:
1 * 100 µG
Artikel-Nr:
(BOSSBS-0318R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0318R-A750
Lokale Artikelnummer::
BOSSBS-0318R-A750
Beschreibung:
PADI4 (peptidyl arginine deiminase, type IV) catalyses the deimination of arginine residues of proteins. Down-regulates histone H3 and H4 arginine methylation, both by preventing arginine methylation by CARM1 and HRMT1L2/PRMT1 and by converting methylarginine to citrulline. subcellular location at cytoplasmic granules. Belongs to the protein arginine deiminase family. This gene may play a role in granulocyte and macrophage development leading to inflammation and immune response.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0318R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0318R-A680
Lokale Artikelnummer::
BOSSBS-0318R-A680
Beschreibung:
PADI4 (peptidyl arginine deiminase, type IV) catalyses the deimination of arginine residues of proteins. Down-regulates histone H3 and H4 arginine methylation, both by preventing arginine methylation by CARM1 and HRMT1L2/PRMT1 and by converting methylarginine to citrulline. subcellular location at cytoplasmic granules. Belongs to the protein arginine deiminase family. This gene may play a role in granulocyte and macrophage development leading to inflammation and immune response.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1564R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1564R-HRP
Lokale Artikelnummer::
BOSSBS-1564R-HRP
Beschreibung:
The Annexins are a family of structurally similar proteins. Annexins bind to phospholipids and may be involved in regulation of membrane transport, membrane channel activity, and interaction of the cell membrane with the extracellular matrix. Annexin A4 (ANXA4) belongs to the annexin family of calcium dependent phospholipid binding proteins. Although their functions are still not clearly defined, several members of the annexin family have been implicated in membrane related events along exocytotic and endocytotic pathways. ANXA4 has 45 to 59% identity with other members of its family and shares a similar size and exon intron organization. Isolated from human placenta, ANXA4 encodes a protein that has possible interactions with ATP, and has in vitro anticoagulant activity and also inhibits phospholipase A2 activity. ANXA4 is almost exclusively expressed in epithelial cells.
VE:
1 * 100 µl
Lieferant:
OMEGA BIO-TEK
Beschreibung:
RNA-Solv® Reagenz ist ein Einreagenzsystem für die Isolierung der Gesamt-RNA aus Zellen und Gewebe. Das Reagenz, eine aus Phenol und Guanidin-Isothiocyanat bestehende Einphasen-Lösung, ist eine Abwandlung der Einphasen-RNA-Isolierungsmethode, die von Chomczynski und Sacchi entwickelt wurde. Die Probe wird im RNA-Solv® Reagenz homogenisiert und lysiert, wodurch die Integrität der RNA erhalten bleibt, während endogene RNasen und andere zelluläre Komponenten aufgeschlossen und denaturiert werden. Die Extraktion des Lysats mit Chloroform denaturiert die Proteine noch mehr und trennt das Gemisch in eine organische und eine wässrige Phase. Die RNA verbleibt ausschließlich in der wässrigen Phase und wird anschließend mit Isopropanol zurückgewonnen.
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Dieses Produkt kann nur an eine Lieferadresse versandt werden die über die entsprechende Lizenzen verfügt. Für weitere Hilfe bitte kontaktieren Sie Ihr VWR Vertriebszentrum.
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