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[cis-3-Methoxycyclobutyl]methanamine+hydrochloride
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[cis-3-Methoxycyclobutyl]methanamine+hydrochloride
Artikel-Nr:
(BOSSBS-11041R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11041R-A555
Lokale Artikelnummer::
BOSSBS-11041R-A555
Beschreibung:
The Bestrophins are a newly described family of anion channels unrelated in primary sequence to any previously characterized channel proteins. Bestrophins were originally defined as a family of over 20 related sequences of the C. elegans. The first mammalian Bestrophin was identified as the vitelliform macular dystrophy (VMD), 1 also known as Best disease. Three more members of the bestrophin family members were cloned and indentified recently, Bestrophin 2, 3 and 4. RT PCR analyses revealed tissue restricted expression of the three genes with both Bestrophin 1 and Bestrophin 2 are abundantly transcribed in colon. Functionally the bestrophines oligomerise to form tetramers and pentamers in order to act as calcium sensitive chloride channels. It has been shown that Bestrophin interacts with beta catalytic subunit of protein phosphatase 2A (PP2Ac). Such protein protein interaction between Bestrophin and PP2Ac and the structural subunit of PP2A, PR65, was confirmed by reciprocal immunoprecipitation. The interaction between PP2Ac and the Bestrophin takes place near the carboxy terminal end of the protein.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11041R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11041R-FITC
Lokale Artikelnummer::
BOSSBS-11041R-FITC
Beschreibung:
The Bestrophins are a newly described family of anion channels unrelated in primary sequence to any previously characterized channel proteins. Bestrophins were originally defined as a family of over 20 related sequences of the C. elegans. The first mammalian Bestrophin was identified as the vitelliform macular dystrophy (VMD), 1 also known as Best disease. Three more members of the bestrophin family members were cloned and indentified recently, Bestrophin 2, 3 and 4. RT PCR analyses revealed tissue restricted expression of the three genes with both Bestrophin 1 and Bestrophin 2 are abundantly transcribed in colon. Functionally the bestrophines oligomerise to form tetramers and pentamers in order to act as calcium sensitive chloride channels. It has been shown that Bestrophin interacts with beta catalytic subunit of protein phosphatase 2A (PP2Ac). Such protein protein interaction between Bestrophin and PP2Ac and the structural subunit of PP2A, PR65, was confirmed by reciprocal immunoprecipitation. The interaction between PP2Ac and the Bestrophin takes place near the carboxy terminal end of the protein.
VE:
1 * 100 µl
Artikel-Nr:
(MAYBCC03603DA)
Lieferant:
Thermo Scientific
Hersteller-Artikelnummer::
CC03603DA
Lokale Artikelnummer::
MAYBCC03603DA
Beschreibung:
1-Methyl-4-imidazolsulfonylchlorid
VE:
1 * 1 g
 This is a MarketSource item. Additional charges may apply
Lieferant:
COMBI-BLOCKS
Beschreibung:
3,5-Dimethylphenylboronsäure
Lieferant:
Sigma-Aldrich
Beschreibung:
Myristoylchlorid, Sigma-Aldrich®
Lieferant:
Sigma-Aldrich
Beschreibung:
α,α,α-Trifluor-p-toluoylchlorid, Sigma-Aldrich®
Lieferant:
FLUOROCHEM
Beschreibung:
2,5-Dimethoxybenzolsulfonylchlorid
Lieferant:
Hach
Beschreibung:
Accessory for test kit, Cold digestion solution, for Chloride cuvette test LCK311, determination of Chloride in concrete
Artikel-Nr:
(SIAL694487-5G)
Lieferant:
Sigma-Aldrich
Hersteller-Artikelnummer::
694487-5G
Lokale Artikelnummer::
SIAL694487-5G
Beschreibung:
2-Methyl-5-nitrobenzolsulfonylchlorid, Sigma-Aldrich®
VE:
1 * 5 g
Lieferant:
FLUOROCHEM
Beschreibung:
2,4-Dichlorbenzolsulfonylchlorid
Lieferant:
FLUOROCHEM
Beschreibung:
2,5-Difluorbenzolsulfonylchlorid
Lieferant:
FLUOROCHEM
Beschreibung:
3,4,5-Trifluorbenzolsulfonylchlorid
Lieferant:
FLUOROCHEM
Beschreibung:
2,4-Difluorbenzolsulfonylchlorid
Lieferant:
Sigma-Aldrich
Beschreibung:
N,N-Dimethylsulfamoylchlorid, Sigma-Aldrich®
Lieferant:
Sigma-Aldrich
Beschreibung:
1,3-Diisopropylimidazoliumchlorid, Sigma-Aldrich®
Artikel-Nr:
(BOSSBS-13046R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13046R
Lokale Artikelnummer::
BOSSBS-13046R
Beschreibung:
Excitatory Amino Acid Transporters (EAATs) are membrane-bound proteins that are localized in glial cells and pre-synaptic glutamatergic nerve endings. EAATs transport the excitatory neurotransmitters L-glutamate and D-aspartate, a process that is essential for terminating the postsynaptic action of glutamate. The re-uptake of amino acid neurotransmitters by EAAT proteins has been shown to protect neurons from excitotoxicity, which is caused by the accumulation of amino acid neurotransmitters. EAAT4 is an aspartate/glutamate transporter that is expressed predominantly in the cerebellum. The transport activity encoded by EAAT4 has high apparent affinity for L-aspartate and L-glutamate, and has a pharmacologic profile consistent with previously described cerebellar transport activities. EAAT5 is a glutamate transporter coupled to a chloride conductance which is expressed primarily in retina. Although EAAT5 shares the structural homologies of the EAAT family, a novel feature of the EAAT5 sequence is a carboxy-terminal motif previously identified in N-ethyl-D-aspartate receptors and potassium channels and shown to confer interactions with a family of synaptic proteins that promote ion channel clustering.
VE:
1 * 100 µl
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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