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2-Chloro-4-methylnicotinic+acid+ethyl+ester
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2-Chloro-4-methylnicotinic+acid+ethyl+ester
Artikel-Nr:
(BOSSBS-11318R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11318R-A555
Lokale Artikelnummer::
BOSSBS-11318R-A555
Beschreibung:
The human ataxin-7 gene, also known as spinocerebellar ataxia 7 or SCA7, maps to chromosome 3p13-p12, has a 2,727-bp open reading frame, and encodes a 892 amino acid protein containing a nuclear localization signal and a polyglutamine tract (1,2). SCA7 is an autosomal dominant neurodegenerative disorder characterized by ataxia and selective neuronal cell loss caused by the expansion of a translated CAG repeat encoding a polyglutamine tract in ataxin-7, which is the SCA7 gene product (3,4). Ataxin-7 is expressed within neurons both affected and unaffected in SCA7 pathology with subcellular localization being variable depending upon the neuronal subtype (5). Polyglutamine expanded in ataxin-7 may carry out its pathogenic effects in the nucleus by altering the matrix-associated nuclear structure and/or by disrupting nucleolar function (6).
VE:
1 * 100 µl
Lieferant:
BIOLEGEND INC
Beschreibung:
Human recombinant IL-12 (p70) insect cells
Lieferant:
Stemcell Technologies
Beschreibung:
Interleukin 12 (IL-12p70) is a heterodimeric cytokine composed of p35 and p40 subunits. IL-12 is produced by monocytes, macrophages, dendritic cells, neutrophils and B cells in response to bacterial products and cytokines such as IFN-γ. The IL-12 receptor is expressed on T, NK, and dendritic cells. Upon binding, IL-12 initiates signaling via the JAK/STAT signaling pathway and stimulates NK, B, and T cells to produce IFN-γ (Watford <i>et al.</i>). It also regulates cytokine synthesis, proliferation of T and NK cells, and stimulates differentiation of CD4+ and CD8+ T cells (Germann and Rüde). Mice that are deficient in IL-12 are susceptible to many intracellular pathogens and have impaired IFN-γ secretion, Th1 differentiation and NK cytolytic activity; however, Th2 development and IL-4 production are enhanced (Watford <i>et al.</i>).
Lieferant:
FLUOROCHEM
Beschreibung:
4-Fluor-o-phenylendiamin
Artikel-Nr:
(PRSI5745P)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
5745P
Lokale Artikelnummer::
PRSI5745P
Beschreibung:
PIAS3 peptide is used for blocking the activity of PIAS3 antibody.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI5295P)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
5295P
Lokale Artikelnummer::
PRSI5295P
Beschreibung:
IRGC peptide is used for blocking the activity of IRGC antibody.
VE:
1 * 50 µG
Artikel-Nr:
(PIER17919)
Lieferant:
Thermo Scientific
Hersteller-Artikelnummer::
17919
Lokale Artikelnummer::
PIER17919
Beschreibung:
N,N,N',N'-Tetramethylethylendiamin (TEMED)
VE:
1 * 25 mL
Artikel-Nr:
(ABNOMAB23650.500UG)
Lieferant:
Abnova
Hersteller-Artikelnummer::
MAB23650.500UG
Lokale Artikelnummer::
ABNOMAB23650.500UG
Beschreibung:
Anti-CD90 Rat Monoclonal Antibody [clone: MTHY-1.2]
VE:
1 * 500 µG
Artikel-Nr:
(BOSSBS-13508R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13508R-CY7
Lokale Artikelnummer::
BOSSBS-13508R-CY7
Beschreibung:
G2A (for G2 accumulation) is a seven transmembrane G protein-coupled receptor that is upregulated in response to DNA damage and stress (1). G2A is predominantly expressed in hematopoietic tissues and in hematopoietic stem cells, and it is more highly detected in pro-B cells, while lower expression is observed in immature B cells and pre-B cells (1,2). G2A is expressed throughout T cell maturation, and it is further increased in response to T-cell activation (3). Ectopic expression of a G2A fusion protein in NIH/3T3 fibroblasts induces a cell cycle arrest that is consistent with a block at the G2/M transition (1,4). G2A is also able to attenuate the proliferative effects of Bcr-Abl, a chimeric tyrosine kinase oncogene, suggesting that G2A possesses anti-oncogenic properties (5). The amino acid sequence of G2A contains a destruction box motif that is consistently observed in cyclins, where it is required for ubiquitination and proteolytic degradation (6).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11879R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11879R-CY3
Lokale Artikelnummer::
BOSSBS-11879R-CY3
Beschreibung:
The leucine-rich (LRR) repeat is a 20-30 amino acid motif that forms a hydrophobic å/∫ horseshoe fold, allowing it to accommodate several leucine residues within a tightly packed core. All LRR repeats contain a variable segment and a highly conserved segment, the latter of which accounts for 11 or 12 residues of the entire LRR motif. Leucine-rich glioma-inactivated protein 3 (LGI3), also known as LGI1-like protein 4 (LGIL4) or leucine-rich repeat LGI family member 3, is a 548 amino acid secretory protein. LGI3 contains five LRR repeats and seven EAR repeats. Widely expressed, with highest levels in brain and lung, LGI3 has been shown to colocalize with endocytosis-associated proteins, lipid raft markers, and Syntaxin. The gene encoding LGI3 maps to chromosome 8p21.3.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13508R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13508R-CY3
Lokale Artikelnummer::
BOSSBS-13508R-CY3
Beschreibung:
G2A (for G2 accumulation) is a seven transmembrane G protein-coupled receptor that is upregulated in response to DNA damage and stress (1). G2A is predominantly expressed in hematopoietic tissues and in hematopoietic stem cells, and it is more highly detected in pro-B cells, while lower expression is observed in immature B cells and pre-B cells (1,2). G2A is expressed throughout T cell maturation, and it is further increased in response to T-cell activation (3). Ectopic expression of a G2A fusion protein in NIH/3T3 fibroblasts induces a cell cycle arrest that is consistent with a block at the G2/M transition (1,4). G2A is also able to attenuate the proliferative effects of Bcr-Abl, a chimeric tyrosine kinase oncogene, suggesting that G2A possesses anti-oncogenic properties (5). The amino acid sequence of G2A contains a destruction box motif that is consistently observed in cyclins, where it is required for ubiquitination and proteolytic degradation (6).
VE:
1 * 100 µl
Lieferant:
Restek
Beschreibung:
Resprep®, Gasket, 12-port, Für: SPE manifolds, Resprep®
Artikel-Nr:
(MOLE10908583-25G)
Lieferant:
Molekula
Hersteller-Artikelnummer::
10908583-25G
Lokale Artikelnummer::
MOLE10908583-25G
Beschreibung:
o-Phenylendiacetonitril
VE:
1 * 25 g
 This is a MarketSource item. Additional charges may apply
Artikel-Nr:
(614-0189)
Lieferant:
GERBER FUNKE
Hersteller-Artikelnummer::
3875
Lokale Artikelnummer::
GERB3875
Beschreibung:
Stativ, Holz, für 12 Extraktionsröhrchen nach Mojonnier
VE:
1 * 1 ST
Artikel-Nr:
(USBI040735)
Lieferant:
US Biological
Hersteller-Artikelnummer::
040735
Lokale Artikelnummer::
USBI040735
Beschreibung:
Anti-RAB12 Rabbit Polyclonal Antibody
VE:
1 * 200 µl
Lieferant:
Thermo Scientific
Beschreibung:
3,4-Dimethyl-o-phenylendiamin
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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