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[2-(3,4-Dimethylphenoxy)phenyl]methanol
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[2-(3,4-Dimethylphenoxy)phenyl]methanol
Lieferant:
Biotium
Beschreibung:
Recognizes a cluster of proteins between 70-80 kDa, identified as tyrosinase. Occasionally a minor band at 55 kDa is also detected. This MAb shows no cross-reaction with MAGE-1 and tyrosinase-related protein 1, TRP-1/gp75. Tyrosinase is a copper-containing metalloglycoprotein that catalyzes several steps in the melanin pigment biosynthetic pathway; the hydroxylation of tyrosine to L-3,4-dihydroxy-phenylalanine (dopa), and the subsequent oxidation of dopa to dopaquinone. Mutations of the tyrosinase gene occur in various forms of albinism. Tyrosinase is one of the targets for cytotoxic T-cell recognition in melanoma patients. Staining of melanomas with this MAb shows tyrosinase in melanotic as well as amelanotic variants. This MAb is a useful marker for melanocytes and melanomas.
Lieferant:
Biotium
Beschreibung:
Recognizes a cluster of proteins between 70-80 kDa, identified as tyrosinase. Occasionally a minor band at 55 kDa is also detected. This MAb shows no cross-reaction with MAGE-1 and tyrosinase-related protein 1, TRP-1/gp75. Tyrosinase is a copper-containing metalloglycoprotein that catalyzes several steps in the melanin pigment biosynthetic pathway; the hydroxylation of tyrosine to L-3,4-dihydroxy-phenylalanine (dopa), and the subsequent oxidation of dopa to dopaquinone. Mutations of the tyrosinase gene occur in various forms of albinism. Tyrosinase is one of the targets for cytotoxic T-cell recognition in melanoma patients. Staining of melanomas with this MAb shows tyrosinase in melanotic as well as amelanotic variants. This MAb is a useful marker for melanocytes and melanomas.
Artikel-Nr:
(BOSSBS-5373R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5373R-A750
Lokale Artikelnummer::
BOSSBS-5373R-A750
Beschreibung:
Heterotrimeric G protein-mediated signal transduction is a dynamically regulated process with the intensity of signal decreasing over time despite the continued presence of the agonist (1,2). G protein-coupled receptor kinases (GRKs) are activated by activated G protein-coupled receptors, and they function to phosphorylate and inactivate cell surface receptors in the heterotrimeric G protein signaling cascade (3,4). GIT1 (for GRK-interactor 1) and GIT2 are GTPase-activating proteins (GAP) for members of the ADP ribosylation factor (ARF) family of small GTP-binding proteins, which are involved in vesicular trafficking (5,6). GIT1 overexpression results in reduced internalization and resensitization of b2-adrenergic receptor, thus reducing b2-adrenergic receptor signaling (5).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5372R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5372R-CY7
Lokale Artikelnummer::
BOSSBS-5372R-CY7
Beschreibung:
Heterotrimeric G protein-mediated signal transduction is a dynamically regulated process with the intensity of signal decreasing over time despite the continued presence of the agonist (1,2). G protein-coupled receptor kinases (GRKs) are activated by activated G protein-coupled receptors, and they function to phosphorylate and inactivate cell surface receptors in the heterotrimeric G protein signaling cascade (3,4). GIT1 (for GRK-interactor 1) and GIT2 are GTPase-activating proteins (GAP) for members of the ADP ribosylation factor (ARF) family of small GTP-binding proteins, which are involved in vesicular trafficking (5,6). GIT1 overexpression results in reduced internalization and resensitization of b2-adrenergic receptor, thus reducing b2-adrenergic receptor signaling (5).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11287R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11287R-FITC
Lokale Artikelnummer::
BOSSBS-11287R-FITC
Beschreibung:
Lymphotactin is a chemokine-like molecule produced selectively, if not exclusively, by activated CD8+ T cells (1). Lymphotactin is a C-type member of the chemokine superfamily, but retains only the 2nd and 4th of the four cysteine residues conserved in other chemokines (3,4). In normal tissues, lymphotactin is expressed at high levels in spleen, thymus, small intestine, and peripheral blood leukocytes, as well as at low levels in lung, prostate, and ovary (2). Lymphotactin is chemotactic for CD4+ and CD8+ T cells but not for monocytes, and induces a rise in intracellular calcium in peripheral blood lymphocytes (1). The specific receptor for lymphotactin is XCR1, a member of the G protein-coupled receptor family (5). The gene which encodes lymphotactin maps to human chromosome 1q23 (1,2).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11287R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11287R-HRP
Lokale Artikelnummer::
BOSSBS-11287R-HRP
Beschreibung:
Lymphotactin is a chemokine-like molecule produced selectively, if not exclusively, by activated CD8+ T cells (1). Lymphotactin is a C-type member of the chemokine superfamily, but retains only the 2nd and 4th of the four cysteine residues conserved in other chemokines (3,4). In normal tissues, lymphotactin is expressed at high levels in spleen, thymus, small intestine, and peripheral blood leukocytes, as well as at low levels in lung, prostate, and ovary (2). Lymphotactin is chemotactic for CD4+ and CD8+ T cells but not for monocytes, and induces a rise in intracellular calcium in peripheral blood lymphocytes (1). The specific receptor for lymphotactin is XCR1, a member of the G protein-coupled receptor family (5). The gene which encodes lymphotactin maps to human chromosome 1q23 (1,2).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5372R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5372R-CY3
Lokale Artikelnummer::
BOSSBS-5372R-CY3
Beschreibung:
Heterotrimeric G protein-mediated signal transduction is a dynamically regulated process with the intensity of signal decreasing over time despite the continued presence of the agonist (1,2). G protein-coupled receptor kinases (GRKs) are activated by activated G protein-coupled receptors, and they function to phosphorylate and inactivate cell surface receptors in the heterotrimeric G protein signaling cascade (3,4). GIT1 (for GRK-interactor 1) and GIT2 are GTPase-activating proteins (GAP) for members of the ADP ribosylation factor (ARF) family of small GTP-binding proteins, which are involved in vesicular trafficking (5,6). GIT1 overexpression results in reduced internalization and resensitization of b2-adrenergic receptor, thus reducing b2-adrenergic receptor signaling (5).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5373R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5373R-CY3
Lokale Artikelnummer::
BOSSBS-5373R-CY3
Beschreibung:
Heterotrimeric G protein-mediated signal transduction is a dynamically regulated process with the intensity of signal decreasing over time despite the continued presence of the agonist (1,2). G protein-coupled receptor kinases (GRKs) are activated by activated G protein-coupled receptors, and they function to phosphorylate and inactivate cell surface receptors in the heterotrimeric G protein signaling cascade (3,4). GIT1 (for GRK-interactor 1) and GIT2 are GTPase-activating proteins (GAP) for members of the ADP ribosylation factor (ARF) family of small GTP-binding proteins, which are involved in vesicular trafficking (5,6). GIT1 overexpression results in reduced internalization and resensitization of b2-adrenergic receptor, thus reducing b2-adrenergic receptor signaling (5).
VE:
1 * 100 µl
Artikel-Nr:
(BLDPBD16437-100MG)
Lieferant:
BLD PHARMATECH GMBH
Hersteller-Artikelnummer::
BD16437-100MG
Lokale Artikelnummer::
BLDPBD16437-100MG
Beschreibung:
Boc-(R)-3-amino-4-(3-trifluoromethylphenyl)butyric acid 98%
VE:
1 * 100 mg
Lieferant:
Thermo Scientific
Beschreibung:
1,4-Diazabicyclo[3.2.2]nonane 95%
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
1,4-Bis(2-methylstyryl)benzene
Artikel-Nr:
(APOSPC408142-5G)
Lieferant:
APOLLO SCIENTIFIC
Hersteller-Artikelnummer::
PC408142-5G
Lokale Artikelnummer::
APOSPC408142-5G
Beschreibung:
3,3,3-Trifluoro-1-phenylpropan-1-one 99%
VE:
1 * 5 g
Artikel-Nr:
(BLDPBD261519-1G)
Lieferant:
BLD PHARMATECH GMBH
Hersteller-Artikelnummer::
BD261519-1G
Lokale Artikelnummer::
BLDPBD261519-1G
Beschreibung:
3-Methyl-4-trifluoromethoxyphenylboronic acid 97%
VE:
1 * 1 g
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
2,2,2,2',6'-Pentafluoro-3'-(trifluoromethyl)acetophenone
Artikel-Nr:
(APOSOR13154-100MG)
Lieferant:
APOLLO SCIENTIFIC
Hersteller-Artikelnummer::
OR13154-100MG
Lokale Artikelnummer::
APOSOR13154-100MG
Beschreibung:
3-(3-Hydroxypropyl)benzeneboronic acid
VE:
1 * 100 mg
Lieferant:
APOLLO SCIENTIFIC
Beschreibung:
4-Fluor-2-(trifluormethyl)benzylamin 97%
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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