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β-tri-Calciumphosphat+(β-Phase)
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β-tri-Calciumphosphat+(β-Phase)
Artikel-Nr:
(BOSSBS-3092R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3092R-CY7
Lokale Artikelnummer::
BOSSBS-3092R-CY7
Beschreibung:
Plays a key role in the control of the eukaryotic cell cycle by modulating the centrosome cycle as well as mitotic onset; promotes G2-M transition, and regulates G1 progress and G1-S transition via association with multiple interphase cyclins. Required in higher cells for entry into S-phase and mitosis. Phosphorylates PARVA/actopaxin, APC, AMPH, APC, BARD1, Bcl-xL/BCL2L1, BRCA2, CALD1, CASP8, CDC7, CDC20, CDC25A, CDC25C, CC2D1A, CSNK2 proteins/CKII, FZR1/CDH1, CDK7, CEBPB, CHAMP1, DMD/dystrophin, EEF1 proteins/EF-1, EZH2, KIF11/EG5, EGFR, FANCG, FOS, GFAP, GOLGA2/GM130, GRASP1, UBE2A/hHR6A, HIST1H1 proteins/histone H1, HMGA1, HIVEP3/KRC, LMNA, LMNB, LMNC, LBR, LATS1, MAP1B, MAP4, MARCKS, MCM2, MCM4, MKLP1, MYB, NEFH, NFIC, NPC/nuclear pore complex, PITPNM1/NIR2, NPM1, NCL, NUCKS1, NPM1/numatrin, ORC1, PRKAR2A, EEF1E1/p18, EIF3F/p47, p53/TP53, NONO/p54NRB, PAPOLA, PLEC/plectin, RB1, UL40/R2, RAB4A, RAP1GAP, RCC1, RPS6KB1/S6K1, KHDRBS1/SAM68, ESPL1, SKI, BIRC5/survivin, STIP1, TEX14, beta-tubulins, MAPT/TAU, NEDD1, VIM/vimentin, TK1, FOXO1, RUNX1/AML1, SIRT2 and RUNX2. CDK1/CDC2-cyclin-B controls pronuclear union in interphase fertilized eggs. Essential for early stages of embryonic development. During G2 and early mitosis, CDC25A/B/C-mediated dephosphorylation activates CDK1/cyclin complexes which phosphorylate several substrates that trigger at least centrosome separation, Golgi dynamics, nuclear envelope breakdown and chromosome condensation. Once chromosomes are condensed and aligned at the metaphase plate, CDK1 activity is switched off by WEE1- and PKMYT1-mediated phosphorylation to allow sister chromatid separation, chromosome decondensation, reformation of the nuclear envelope and cytokinesis. Inactivated by PKR/EIF2AK2- and WEE1-mediated phosphorylation upon DNA damage to stop cell cycle and genome replication at the G2 checkpoint thus facilitating DNA repair.
VE:
1 * 100 µl
Lieferant:
PanReac AppliChem
Beschreibung:
TRItidy G™ is based on the single step simultaneous isolation of RNA, DNA and proteins from cell and tissue samples (Chomczynski, P. (1993), BioTechniques 15, p.532 - 537). RNA is selectively retained in the aqueous phase during acidic GuSCN/phenol extraction; DNA and proteins are isolated from the organic phase by ethanol and isopropanol precipitation, respectively.
Artikel-Nr:
(PRSI32-114)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
32-114
Lokale Artikelnummer::
PRSI32-114
Beschreibung:
AURKB (aurora kinase B, AIK2 or aurora-B), with 344-amino acid protein(about 39 kDa),localizes to microtubules near kinetochores, specifically to the specialized microtubules called K-fibers. AURKB is a mitotic protein kinase, which phosphorylates histone H3 and regulates Chromosomal segregation during mitosis and meiosis.It may regulates several stages of mitosis such as centrosome separation, chromosome segregation and cytokinesis.Component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. ARK-2 transcripts arepresent at high levels in human thymus and fetal liver.ARK-2 protein levels are maximal during both S and G2/M phases
VE:
1 * 100 µl
Artikel-Nr:
(PRSI5721)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
5721
Lokale Artikelnummer::
PRSI5721
Beschreibung:
APC2 Antibody: Cell cycle regulated protein ubiquitination and degradation within subcellular domains is thought to be essential for the normal progression of mitosis. APC2 is a highly conserved component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. APC/C is responsible for degrading anaphase inhibitors, mitotic cyclins, and spindle-associated proteins ensuring that events of mitosis take place in proper sequence. The individual APC/C components mRNA and protein levels are expressed at approximately the same levels in most tissues and cell lines, suggesting that they perform their functions as part of a complex. Like APC11, APC2 contains cullin and RING finger domains that are thought to be important in regulating ubiquitination activity.
VE:
1 * 100 µG
Lieferant:
VARIAN
Beschreibung:
Native silica is generally regarded as the most polar SPE sorbent available. Bond Elut™ SI is particularly effective at separating compounds with a very similar structure. Applying the analytes in a non-polar solvent, then increasing the solvent polarity by increasing the concentration of a polar modifier, such as THF or ethyl acetate, delivers effective separations.
Lieferant:
NABERTHERM
Beschreibung:
Mit Ihrem überzeugenden Preis-Leistungs-Verhältnis und der schnellen Aufheizgeschwindigkeit eignen sich diese kompakten Muffelöfen für viele Anwendungen im Labor. Qualitätsmerkmale wie das doppelwandige Ofengehäuse aus nicht rostendem Edelstahl, der kompakte, leichte Aufbau oder die in Quarzglasrohren eingelegten Heizelemente machen diese Modelle zum zuverlässigen Partner für Ihre Anwendung. Die Maximaltemperatur der Öfen liegt bei 1100 °C, die Arbeitstemperatur bei 1050 °C.
Artikel-Nr:
(PRSI79-644)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
79-644
Lokale Artikelnummer::
PRSI79-644
Beschreibung:
Transcription regulator involved in inner cell mass and embryonic stem (ES) cells proliferation and self-renewal. Imposes pluripotency on ES cells and prevents their differentiation towards extraembryonic endoderm and trophectoderm lineages. Blocks bone morphogenetic protein-induced mesoderm differentiation of ES cells by physically interacting with SMAD1 and interfering with the recruitment of coactivators to the active SMAD transcriptional complexes By similarity. Acts as a transcriptional activator or repressor By similarity. Binds optimally to the DNA consensus sequence 5'-TAAT[GT][GT]-3' or 5'-[CG][GA][CG]C[GC]ATTAN[GC]-3' By similarity. When overexpressed, promotes cells to enter into S phase and proliferation
VE:
1 * 100 µG
Artikel-Nr:
(PRSIXP-5164BT)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
XP-5164BT
Lokale Artikelnummer::
PRSIXP-5164BT
Beschreibung:
Interleukin 11 is a pleiotropic cytokine produced by mesenchymal-derived adherent cells. IL11 shares many functions of IL6 and LIF, including potentiation of megakaryocyte activity, enhancement of human myeloma cell proliferation, and enhancement of hepatic acute phase protein production. Interleukin 11 directly stimulates the proliferation of hematopoietic stem cells and megakaryocyte progenitor cells, and induces megakaryocyte maturation resulting in increased platelet production. Clinically it is used to prevent severe thrombocytopenia and the reduction of the need for platelet transfusion following myelosuppressive chemotherapy.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI28-974)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
28-974
Lokale Artikelnummer::
PRSI28-974
Beschreibung:
This gene was identified based on its homology to the gene encoding the RING3 protein, a serine/threonine kinase. The gene localizes to 9q34, a region which contains several major histocompatibility complex (MHC) genes. BRD3 is ubiquitously expressed in human adult and fetal tissues. BRD3 is markedly expressed in undifferentiated ES cells, whereas the expression was reduced upon endothelial differentiation. BRD3 plays a role in regulation of cell proliferation by allowing cells to enter the proliferative phase of the angiogenic process.BRD3 is also involved in bladder cancer.
VE:
1 * 100 µG
Artikel-Nr:
(PRSI79-266)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
79-266
Lokale Artikelnummer::
PRSI79-266
Beschreibung:
NFKB has been detected in numerous cell types that express cytokines, chemokines, growth factors, cell adhesion molecules, and some acute phase proteins in health and in various disease states. NFKB is activated by a wide variety of stimuli such as cytokines, oxidant-free radicals, inhaled particles, ultraviolet irradiation, and bacterial or viral products. Inappropriate activation of NF-κ-B has been linked to inflammatory events associated with autoimmune arthritis, asthma, septic shock, lung fibrosis, glomerulonephritis, atherosclerosis, and AIDS. In contrast, complete and persistent inhibition of NF-κ-B has been linked directly to apoptosis, inappropriate immune cell development, and delayed cell growth.
VE:
1 * 100 µG
Lieferant:
ZEISS
Beschreibung:
Primo Vert ist für Hochschul- und Forschungslabore im Bereich Zellkultur konzipiert.
Artikel-Nr:
(YMCAOS12S03-1546WT)
Lieferant:
YMC
Hersteller-Artikelnummer::
OS12S03-1546WT
Lokale Artikelnummer::
YMCAOS12S03-1546WT
Beschreibung:
Die ProFamily-Reihe wird aus ultrahochreinem Silica (99,999 %) hergestellt, das anschließend einem speziellen Bindungsprozess unterzogen wird. Für die Phasen der ProFamily wird Silica mit einem extrem niedrigen Metallgehalt verwendet, um polare Wechselwirkungen zu unterdrücken, da Metallverunreinigungen dazu führen, dass Silanolgruppen saurer werden.
VE:
1 * 1 ST
 This is a MarketSource item. Additional charges may apply
Artikel-Nr:
(705-0004)
Lieferant:
BEHR
Hersteller-Artikelnummer::
B00217714
Lokale Artikelnummer::
BEHRB00217714
Beschreibung:
Komplettausrüstung zur Vorbereitung und Destillation für gängige Analysen von festen und wässrigen Proben.
VE:
1 * 1 ST
Lieferant:
Thermo Scientific
Beschreibung:
PS, klar, ohne Deckel. Die Platten wurden speziell für quantitative und qualitative Festphasen-Immunoassays (z. B. ELISA) und Bindungsassays entwickelt. Wahlweise mit den Oberflächen MaxiSorp™, PolySorp™, MediSorp™ und MultiSorp™ erhältlich. Alle MaxiSorp™ Platten wurden für ihre Bindungshomogenität zertifiziert.
Artikel-Nr:
(BOSSBS-3092R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3092R-CY5
Lokale Artikelnummer::
BOSSBS-3092R-CY5
Beschreibung:
Plays a key role in the control of the eukaryotic cell cycle by modulating the centrosome cycle as well as mitotic onset; promotes G2-M transition, and regulates G1 progress and G1-S transition via association with multiple interphase cyclins. Required in higher cells for entry into S-phase and mitosis. Phosphorylates PARVA/actopaxin, APC, AMPH, APC, BARD1, Bcl-xL/BCL2L1, BRCA2, CALD1, CASP8, CDC7, CDC20, CDC25A, CDC25C, CC2D1A, CSNK2 proteins/CKII, FZR1/CDH1, CDK7, CEBPB, CHAMP1, DMD/dystrophin, EEF1 proteins/EF-1, EZH2, KIF11/EG5, EGFR, FANCG, FOS, GFAP, GOLGA2/GM130, GRASP1, UBE2A/hHR6A, HIST1H1 proteins/histone H1, HMGA1, HIVEP3/KRC, LMNA, LMNB, LMNC, LBR, LATS1, MAP1B, MAP4, MARCKS, MCM2, MCM4, MKLP1, MYB, NEFH, NFIC, NPC/nuclear pore complex, PITPNM1/NIR2, NPM1, NCL, NUCKS1, NPM1/numatrin, ORC1, PRKAR2A, EEF1E1/p18, EIF3F/p47, p53/TP53, NONO/p54NRB, PAPOLA, PLEC/plectin, RB1, UL40/R2, RAB4A, RAP1GAP, RCC1, RPS6KB1/S6K1, KHDRBS1/SAM68, ESPL1, SKI, BIRC5/survivin, STIP1, TEX14, beta-tubulins, MAPT/TAU, NEDD1, VIM/vimentin, TK1, FOXO1, RUNX1/AML1, SIRT2 and RUNX2. CDK1/CDC2-cyclin-B controls pronuclear union in interphase fertilized eggs. Essential for early stages of embryonic development. During G2 and early mitosis, CDC25A/B/C-mediated dephosphorylation activates CDK1/cyclin complexes which phosphorylate several substrates that trigger at least centrosome separation, Golgi dynamics, nuclear envelope breakdown and chromosome condensation. Once chromosomes are condensed and aligned at the metaphase plate, CDK1 activity is switched off by WEE1- and PKMYT1-mediated phosphorylation to allow sister chromatid separation, chromosome decondensation, reformation of the nuclear envelope and cytokinesis. Inactivated by PKR/EIF2AK2- and WEE1-mediated phosphorylation upon DNA damage to stop cell cycle and genome replication at the G2 checkpoint thus facilitating DNA repair.
VE:
1 * 100 µl
Lieferant:
WATERS
Beschreibung:
These cartridges deliver the option of minimum sample preparation. Consists of moulded, high purity PP syringe-barrel bodies with two PE frits to contain the packing material.
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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