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β-tri-Calciumphosphat+(β-Phase)
Artikel-Nr:
(JACK209-035-098)
Lieferant:
Jackson Immuno Research
Hersteller-Artikelnummer::
209-035-098
Lokale Artikelnummer::
JACK209-035-098
Beschreibung:
Whole IgG antibodies are isolated as intact molecules from antisera by immunoaffinity chromatography. They have an Fc portion and two antigen binding Fab portions joined together by disulfide bonds and therefore they are divalent. The average molecular weight is reported to be about 160 kDa. The whole IgG form of antibodies is suitable for the majority of immunodetection procedures and is the most cost effective. Based on immunoelectrophoresis and/or ELISA, the antibody reacts with the Fc portion of human IgG heavy chain but not with the Fab portion of human IgG. No antibody was detected against human IgM or IgA, or against non-immunoglobulin serum proteins. The antibody exhibits inherent minimal cross-reaction to mouse serum proteins and has been tested by ELISA and/or solid-phase adsorbed to ensure minimal cross-reaction with bovine, horse and mouse serum proteins. The antibody may cross-react with immunoglobulins from other species.
VE:
1 * 1 mL
 This is a MarketSource item. Additional charges may apply
Artikel-Nr:
(PRSI5725)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
5725
Lokale Artikelnummer::
PRSI5725
Beschreibung:
APC4 Antibody: Cell cycle regulated protein ubiquitination and degradation within subcellular domains is thought to be essential for the normal progression of mitosis. APC4 is a highly conserved component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. APC/C is responsible for degrading anaphase inhibitors, mitotic cyclins, and spindle-associated proteins ensuring that events of mitosis take place in proper sequence. The individual APC/C components mRNA and protein levels are expressed at approximately the same levels in most tissues and cell lines, suggesting that they perform their functions as part of a complex. While little is known of APC4, it is thought that APC4 associates with other APC/C components APC1, APC5, and CDC23 interdependently, such that loss of any one subunit reduces binding between the remaining three.
VE:
1 * 100 µG
Artikel-Nr:
(85398.290)
Lieferant:
VWR Chemicals
Lokale Artikelnummer::
VWRC85398.290
Beschreibung:
N-Methyl-2-pyrrolidon (NMP) ≥99,8%, PESTINORM® für die Headspace-Gaschromatographie
VE:
1 * 1 L
Artikel-Nr:
(SPCMA1107-12KG)
Lieferant:
Spectrum Chemical
Hersteller-Artikelnummer::
A1107-12KG
Lokale Artikelnummer::
SPCMA1107-12KG
Beschreibung:
Aluminum Potassium Sulfate, Crystal, FCC is commonly used as an additive to baking powder to provide a second leavening phase at high temperatures. The FCC grade meets the requirements of the Food Chemical Codex indicates and is suitable for all food, beverage and nutritional supplement applications. Spectrum Chemical offers over 300 Food grade chemical ingredients packaged in laboratory size bottles to production drum quantities and are manufactured, packaged and stored under current Good Manufacturing Practices (cGMP) per 21CFR part 211 in FDA registered and inspected facilities.
VE:
1 * 12 kg
Artikel-Nr:
(BOSSBS-3092R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3092R-CY3
Lokale Artikelnummer::
BOSSBS-3092R-CY3
Beschreibung:
Plays a key role in the control of the eukaryotic cell cycle by modulating the centrosome cycle as well as mitotic onset; promotes G2-M transition, and regulates G1 progress and G1-S transition via association with multiple interphase cyclins. Required in higher cells for entry into S-phase and mitosis. Phosphorylates PARVA/actopaxin, APC, AMPH, APC, BARD1, Bcl-xL/BCL2L1, BRCA2, CALD1, CASP8, CDC7, CDC20, CDC25A, CDC25C, CC2D1A, CSNK2 proteins/CKII, FZR1/CDH1, CDK7, CEBPB, CHAMP1, DMD/dystrophin, EEF1 proteins/EF-1, EZH2, KIF11/EG5, EGFR, FANCG, FOS, GFAP, GOLGA2/GM130, GRASP1, UBE2A/hHR6A, HIST1H1 proteins/histone H1, HMGA1, HIVEP3/KRC, LMNA, LMNB, LMNC, LBR, LATS1, MAP1B, MAP4, MARCKS, MCM2, MCM4, MKLP1, MYB, NEFH, NFIC, NPC/nuclear pore complex, PITPNM1/NIR2, NPM1, NCL, NUCKS1, NPM1/numatrin, ORC1, PRKAR2A, EEF1E1/p18, EIF3F/p47, p53/TP53, NONO/p54NRB, PAPOLA, PLEC/plectin, RB1, UL40/R2, RAB4A, RAP1GAP, RCC1, RPS6KB1/S6K1, KHDRBS1/SAM68, ESPL1, SKI, BIRC5/survivin, STIP1, TEX14, beta-tubulins, MAPT/TAU, NEDD1, VIM/vimentin, TK1, FOXO1, RUNX1/AML1, SIRT2 and RUNX2. CDK1/CDC2-cyclin-B controls pronuclear union in interphase fertilized eggs. Essential for early stages of embryonic development. During G2 and early mitosis, CDC25A/B/C-mediated dephosphorylation activates CDK1/cyclin complexes which phosphorylate several substrates that trigger at least centrosome separation, Golgi dynamics, nuclear envelope breakdown and chromosome condensation. Once chromosomes are condensed and aligned at the metaphase plate, CDK1 activity is switched off by WEE1- and PKMYT1-mediated phosphorylation to allow sister chromatid separation, chromosome decondensation, reformation of the nuclear envelope and cytokinesis. Inactivated by PKR/EIF2AK2- and WEE1-mediated phosphorylation upon DNA damage to stop cell cycle and genome replication at the G2 checkpoint thus facilitating DNA repair.
VE:
1 * 100 µl
Artikel-Nr:
(STMC78143.2)
Lieferant:
Stemcell Technologies
Hersteller-Artikelnummer::
78143.2
Lokale Artikelnummer::
STMC78143.2
Beschreibung:
Interleukin 1 beta (IL-1β) is synthesised as an inactive precursor protein or pro-IL-1β. This precursor is cleaved intracellularly by Caspase 1 (IL-1β convertase) to form the active form of the protein that is later secreted (Allan <i>et al.</i>). IL-1β binds to IL-1 receptor and activates intracellular signaling via the MAPK or NF-kB pathway. IL-1β is released by monocytes, tissue macrophages, and dendritic cells in response to infection or injury and induces expression of acute-phase proteins. It also promotes the infiltration of inflammatory and immunocompetent cells from the circulation into the extravascular space and affected tissues, by stimulating the expression of adhesion molecules on endothelial cells. IL-1β also affects other immune cells; for example, it co-stimulates T cell functions together with antigen or mitogen. It also stimulates Th17 differentiation and B cell proliferation in an IL-6-dependent manner. This product is animal component-free.
VE:
1 * 1.000 µG
New Product
This is a MarketSource item. Additional charges may apply
Artikel-Nr:
(STMC100-1404)
Lieferant:
Stemcell Technologies
Hersteller-Artikelnummer::
100-1404
Lokale Artikelnummer::
STMC100-1404
Beschreibung:
Stimulating T cells with HHV8 (K8.1) Peptide pool releases downstream cytokines and upregulates activation markers, enabling antigen-specific T cells to be detected or isolated for analysis. HHV8 (K8.1) Peptide pool is a lyophilised mixture of 55 peptides from glycoprotein K8.1 of human herpesvirus 8 (HHV-8) and consists of 15-mer peptides with 11-amino-acid overlaps that cover amino acids 1 to 228 on K8.1. Expressed in the late-lytic phase, K8.1 is a viral envelope protein that binds to heparin sulfate on the cell surface and facilitates HHV 8 infection (Zoeteweij et al; Birkmann <i>et al.</i>; Wang <i>et al.</i>). Viral peptide pools are useful for a broad range of applications, including vaccine development, immunological research, and diagnostic assay development.
VE:
1 * 1 LE
New Product
This is a MarketSource item. Additional charges may apply
Lieferant:
Restek
Beschreibung:
These cartridges are made of glass fiber disks embedded with C18 or C8 bonded silica. These hydrophobic (nonpolar) silica-based adsorbents are ideal to extract hydrophobic analytes from polar matrices, such as water (e.g., pesticides from water).
Artikel-Nr:
(PRSI90-231)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
90-231
Lokale Artikelnummer::
PRSI90-231
Beschreibung:
Tumour necrosis factor (TNF, cachexin or cachectin and formerly known as tumour necrosis factor-alpha) is a cytokine involved in systemic inflammation and is a member of a group of cytokines that stimulate the acute phase reaction. MultimericTNF-alpha™ is a high activity construct in which two trimeric TNF-alpha ligands are artificially linked via the collagen domain of ACRP30. The receptor TNF-R1 is activated by both the membrane-bound and soluble trimeric forms of TNF-alpha, whereas the receptor TNF-R2 only responds to the membrane-bound form of TNF-alpha (TNF-alpha (human) (multimeric) (rec. ) (Prod. No. AG-40B-0019). Since the MultimericTNF-alpha™ mimics the membrane-bound form (forms oligomers higher than trimer), it is the only TNF-alpha protein that can activate the TNF-R2. For TNF-R1 activation, either "normal" TNF-alpha or MultimericTNF-alpha™ can be used.
VE:
1 * 10 µG
Lieferant:
HAMILTON BONADUZ
Beschreibung:
Diese Anion-Säulenreihe wurde entwickelt, um den besonderen Anforderungen der Anionenanalyse zu entsprechen. Diese vier Säulen decken alle Aspekte der standardmäßigen Anionenanalyse, die Trennung aller 8 gängigen Anionen in einem Durchlauf ab. Das einzigartige Design des stark porösen Verpackungsmaterials mit hoher Quervernetzung und die stark kovalent gebundene Oberflächenchemie gewährleisten eine hervorragende Strapazierfähigkeit und hohe Trennungseffizienz. Die Säulen wurden für die Verwendung mit Karbonat-Bikarbonat-Puffer in beliebiger Konzentration entwickelt. Hydroxidgradienten und viele anderen mobile-Phase sind ebenfalls möglich.
Artikel-Nr:
(PRSI92-663)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
92-663
Lokale Artikelnummer::
PRSI92-663
Beschreibung:
Interleukin-22 (IL-22) was initially identified as a gene induced by IL-9 in mouse T cells and mast cells. Mouse IL-22 cDNA encodes a 179 amino acid residue protein with a putative 33 amino acid signal peptide that is cleaved to generate a 147 amino acid mature protein that shares approximately 79% and 22% sequence identity with human IL22 and IL10, respectively. IL22 has been shown to activate STAT-1 and STAT-3 in several hepatoma cell lines and up-regulate the production of acute phase proteins. IL-22 is produced by normal mouse T cells upon Con A activation. Mouse IL-22 expression is also induced in various organs upon lipopolysaccharide injection, suggesting that IL-22 may be involved in inflammatory responses. The functional IL-22 receptor complex consists of two receptor subunits, IL-22R (previously an orphan receptor named CRF2-9) and IL-10R beta (previously known as CRF2-4), belonging to the class II cytokine receptor family.
VE:
1 * 50 µG
Lieferant:
Merck
Beschreibung:
With their high degree of UV transmittance, low particle count, low acidity and alkalinity and low evaporation residue level, LiChrosolv® solvents are ideal for reproducible separations. Since separations are normally carried out under gradient conditions in analytical HPLC, we offer solvents in 'gradient grade' as well as 'isocratic grade'. This minimises the gradient effect of the solvent involved.
Lieferant:
SMEG
Beschreibung:
Diese Reihe professioneller Smeg-Reinigungs- und Thermodesinfektionsmaschinen wird aus hochwertigen Materialien und Komponenten hergestellt, um optimale Ergebnisse zu erzielen. Die Waschkammern bestehen aus rostfreiem Stahl der Qualität 316 L, der gegen starke Säuren (wie sie in der Pharma- und Lebensmittelindustrie verwendet werden) beständig ist.
Lieferant:
Agilent
Beschreibung:
These HPLC columns are made with type A silica. They are useful for many applications of acidic or neutral compounds. These columns have a higher activity level and are therefore useful for separating isomers or other compounds where silanol activity enhances selectivity.
Lieferant:
Honeywell Chemicals
Beschreibung:
n-Hexan für die Gaschromatographie, Burdick & Jackson™
Artikel-Nr:
(VARI12105032)
Lieferant:
VARIAN
Hersteller-Artikelnummer::
12105032
Lokale Artikelnummer::
VARI12105032
Beschreibung:
Bond Elut™ PCB is a specially designed sorbent which allows for the facile extraction of polychlorinated biphenyl (PCB) compounds from a variety of matrices. Desired analytes can be loaded and eluted using a simple, single solvent method prior to analysis by GC/ECD.
VE:
1 * 50 ST
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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