2\',4\'-Difluorbiphenyl-4-carbonsäure
Lieferant:
Thermo Fisher Scientific
Beschreibung:
Diese Aufbewahrungsröhrchen eignen sich hervorragend für die Lagerung in der Forschung und zur allgemeinen Laborlagerung von wertvollen und genomischen Materialien bis hinunter zur Dampfphase von Flüssigstickstoff (bei Temperaturen bis zu –150 °C). Sie bestehen aus PPCO und besitzen HDPE-Schraubverschlüsse.
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Artikel-Nr:
(USBI030866-APC)
Lieferant:
US Biological
Hersteller-Artikelnummer::
030866-APC
Lokale Artikelnummer::
USBI030866-APC
Beschreibung:
Anti-CDC25C Mouse Monoclonal Antibody (APC (Allophycocyanin)) [clone: 233CT9.6.6]
VE:
1 * 200 µl
Lieferant:
Sigma-Aldrich
Beschreibung:
Mangan(III)acetat Dihydrat, Sigma-Aldrich®
Artikel-Nr:
(BOSSBS-3091R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3091R-A680
Lokale Artikelnummer::
BOSSBS-3091R-A680
Beschreibung:
The cell division control protein cdc2, also known as cyclin dependent kinase 1 (Cdk1) or p34/cdk1, plays a key role in the control of the eukaryotic cell cycle, where it is required for entry into S phase and mitosis. Cdc2 exists as a complex with both cyclin A and cyclin B. The best characterised of these associations is the Cdc2 p34 cyclin B complex, which is required for the G2 to M phase transition. Activation of Cdc2 is controlled at several steps including cyclin binding and phosphorylation of threonine 161. However, the critical regulatory step in activating cdc2 during progression into mitosis appears to be dephosphorylation of Tyr15 and Tyr14. Phosphorylation at Tyr15 and inhibition of Cdc2 is carried out by WEE1 and MIK protein kinases while Tyr15 dephosphorylation and activation of Cdc2 is carried out by the cdc25 phosphatase. The isoform CDC2deltaT is found in breast cancer tissues. Furthermore, cdc2/Cdk1 is a key mediator of neuronal cell death in brain development and degeneration.
VE:
1 * 100 µl
Artikel-Nr:
(567540-5)
Lieferant:
Merck Millipore (Calbiochem)
Hersteller-Artikelnummer::
567540-5
Lokale Artikelnummer::
CALB567540-5
Beschreibung:
Natriumorthovanadat, Millipore®
VE:
1 * 5 g
Artikel-Nr:
(BOSSBS-7832R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7832R-A555
Lokale Artikelnummer::
BOSSBS-7832R-A555
Beschreibung:
Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7832R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7832R-A350
Lokale Artikelnummer::
BOSSBS-7832R-A350
Beschreibung:
Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12486R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12486R-CY5
Lokale Artikelnummer::
BOSSBS-12486R-CY5
Beschreibung:
Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11788R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11788R-CY3
Lokale Artikelnummer::
BOSSBS-11788R-CY3
Beschreibung:
The function of PrP is still under debate. May play a role in neuronal development and synaptic plasticity. May be required for neuronal myelin sheath maintenance. May play a role in iron uptake and iron homeostasis (By similarity). Isoform 2 may act as a growth suppressor by arresting the cell cycle at the G0/G1 phase. Soluble oligomers are toxic to cultured neuroblastoma cells and induce apoptosis (in vitro).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11788R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11788R-A350
Lokale Artikelnummer::
BOSSBS-11788R-A350
Beschreibung:
The function of PrP is still under debate. May play a role in neuronal development and synaptic plasticity. May be required for neuronal myelin sheath maintenance. May play a role in iron uptake and iron homeostasis (By similarity). Isoform 2 may act as a growth suppressor by arresting the cell cycle at the G0/G1 phase. Soluble oligomers are toxic to cultured neuroblastoma cells and induce apoptosis (in vitro).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7832R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7832R-A488
Lokale Artikelnummer::
BOSSBS-7832R-A488
Beschreibung:
Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5634R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5634R-CY5.5
Lokale Artikelnummer::
BOSSBS-5634R-CY5.5
Beschreibung:
NAD-dependent protein deacetylase. Has deacetylase activity towards histone H3K9Ac and H3K56Ac. Modulates acetylation of histone H3 in telomeric chromatin during the S-phase of the cell cycle. Deacetylates histone H3K9Ac at NF-kappa-B target promoters and may down-regulate the expression of a subset of NF-kappa-B target genes. Acts as a corepressor of the transcription factor HIF1A to control the expression of multiple glycolytic genes to regulate glucose homeostasis. Required for genomic stability. Regulates the production of TNF protein. Has a role in the regulation of life span (By similarity). Deacetylation of nucleosomes interferes with RELA binding to target DNA. May be required for the association of WRN with telomeres during S-phase and for normal telomere maintenance. Required for genomic stability. Required for normal IGF1 serum levels and normal glucose homeostasis. Modulates cellular senescence and apoptosis. On DNA damage, promotes DNA end resection via deacetylation of RBBP8. Has very weak deacetylase activity and can bind NAD(+) in the absence of acetylated substrate.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3122R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3122R-CY5
Lokale Artikelnummer::
BOSSBS-3122R-CY5
Beschreibung:
The protein encoded by this gene is a regulatory protein involved in mitosis. The gene product complexes with p34(cdc2) to form the maturation-promoting factor (MPF). Two alternative transcripts have been found, a constitutively expressed transcript and a cell cycle-regulated transcript, that is expressed predominantly during G2/M phase. The different transcripts result from the use of alternate transcription initiation sites. [provided by RefSeq, Jul 2008].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3733R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3733R-CY7
Lokale Artikelnummer::
BOSSBS-3733R-CY7
Beschreibung:
The protein encoded by this gene is a regulatory protein involved in mitosis. The gene product complexes with p34(cdc2) to form the maturation-promoting factor (MPF). Two alternative transcripts have been found, a constitutively expressed transcript and a cell cycle-regulated transcript, that is expressed predominantly during G2/M phase. The different transcripts result from the use of alternate transcription initiation sites. [provided by RefSeq, Jul 2008].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3123R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3123R-CY7
Lokale Artikelnummer::
BOSSBS-3123R-CY7
Beschreibung:
The protein encoded by this gene is a regulatory protein involved in mitosis. The gene product complexes with p34(cdc2) to form the maturation-promoting factor (MPF). Two alternative transcripts have been found, a constitutively expressed transcript and a cell cycle-regulated transcript, that is expressed predominantly during G2/M phase. The different transcripts result from the use of alternate transcription initiation sites. [provided by RefSeq, Jul 2008].
VE:
1 * 100 µl
Lieferant:
Hichrom Limited
Beschreibung:
Diese Vydac TP ist die erste im Vydac-Sortiment entwickelte Reihe weitporiger Medienphasen und ist der Branchenstandard für Peptid- und Proteintrennungen. Die großen Poren des 300-Å-TP-Silica ermöglichen Polypeptidmolekülen vollständigen Zugang zum Inneren der Silica-Poren.
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