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6-Fluoro-4-chromanone
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6-Fluoro-4-chromanone
Artikel-Nr:
(BOSSBS-1160R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1160R-A555
Lokale Artikelnummer::
BOSSBS-1160R-A555
Beschreibung:
Gelsolin is a calcium dependent actin binding protein. It is a potent modulator of actin filament length and gelation. Gelsolin has been shown to exist in at least two variant forms, cytoplasmic gelsolin and plasma gelsolin. Plasma gelsolin has also been called actin depolymerizing factor (ADF) or brevin. Human plasma and rabbit macrophage gelsolins differ by the presence of a 25 amino acid residue extension at the NH2 terminus in the human plasma gelsolin, which appears to account for the difference in relative molecular weights.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5357R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5357R-A555
Lokale Artikelnummer::
BOSSBS-5357R-A555
Beschreibung:
The multi-pass membrane protein encoded by this gene belongs to the G-protein coupled receptor 3 family and GABA-B receptor subfamily. The GABA-B receptors inhibit neuronal activity through G protein-coupled second-messenger systems, which regulate the release of neurotransmitters, and the activity of ion channels and adenylyl cyclase. This receptor subunit forms an active heterodimeric complex with GABA-B receptor subunit 1, neither of which is effective on its own. Allelic variants of this gene have been associated with nicotine dependence.[provided by RefSeq, Jan 2010].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5660R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5660R-A647
Lokale Artikelnummer::
BOSSBS-5660R-A647
Beschreibung:
NF-kappa-B is a ubiquitous transcription factor involved in several biological processes. It is held in the cytoplasm in an inactive state by specific inhibitors. Upon degradation of the inhibitor, NF-kappa-B moves to the nucleus and activates transcription of specific genes. NF-kappa-B is composed of NFKB1 or NFKB2 bound to either REL, RELA, or RELB. The most abundant form of NF-kappa-B is NFKB1 complexed with the product of this gene, RELA. Four transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5661R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5661R-CY7
Lokale Artikelnummer::
BOSSBS-5661R-CY7
Beschreibung:
NF-kappa-B is a ubiquitous transcription factor involved in several biological processes. It is held in the cytoplasm in an inactive state by specific inhibitors. Upon degradation of the inhibitor, NF-kappa-B moves to the nucleus and activates transcription of specific genes. NF-kappa-B is composed of NFKB1 or NFKB2 bound to either REL, RELA, or RELB. The most abundant form of NF-kappa-B is NFKB1 complexed with the product of this gene, RELA. Four transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13016R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13016R-HRP
Lokale Artikelnummer::
BOSSBS-13016R-HRP
Beschreibung:
DNA polymerase specifically involved in DNA repair. Plays an important role in translesion synthesis, where the normal high fidelity DNA polymerases cannot proceed and DNA synthesis stalls. Plays an important role in the repair of UV-induced pyrimidine dimers. Depending on the context, it inserts the correct base, but causes frequent base transitions and transversions. May play a role in hypermutation at immunoglobulin genes. Forms a Schiff base with 5'-deoxyribose phosphate at abasic sites, but does not have lyase activity. Targets POLI to replication foci.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5983R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5983R-FITC
Lokale Artikelnummer::
BOSSBS-5983R-FITC
Beschreibung:
AARE (Acylamino-acid-releasing enzyme) is also known as Acyl-peptide hydrolase. It catalyzes the hydrolysis of the terminal acetylated amino acid preferentially from small acetylated peptides. The acetyl amino acid formed by this hydrolase is further processed to acetate and a free amino acid by an aminoacylase. It can play an important role in destroying oxidatively damaged proteins in living cells. Deletions of this gene locus corresponding to the protein are found in various types of carcinomas, including small cell lung carcinoma and renal cell carcinoma.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1350R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1350R-HRP
Lokale Artikelnummer::
BOSSBS-1350R-HRP
Beschreibung:
Death Associated Protein 5 (DAP5) is a 97 kDa protein with high amino acid sequence homology to Eukaryotic Translation Initiation Factor 4G (eIF4G). Compared with eIF4G, DAP5 lacks the N-terminal region necessary for cap-dependent translation and has a unique C-terminal part functioning as a regulator for interferon-gamma induced cell death. During apoptosis, DAP5 is cleaved at Asp790. The C-terminal truncated form of DAP5 functions as a cap-independent translation initiation factor responsible for the mediation of its own translation during apoptosis.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3428R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3428R-A555
Lokale Artikelnummer::
BOSSBS-3428R-A555
Beschreibung:
Signal transducer and activator of transcription that mediates signaling by type I IFNs (IFN-alpha and IFN-beta). Following type I IFN binding to cell surface receptors, Jak kinases (TYK2 and JAK1) are activated, leading to tyrosine phosphorylation of STAT1 and STAT2. The phosphorylated STATs dimerize, associate with IRF9/ISGF3G to form a complex termed ISGF3 transcription factor, that enters the nucleus. ISGF3 binds to the IFN stimulated response element (ISRE) to activate the transcription of interferon stimulated genes, which drive the cell in an antiviral state.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4989R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4989R-FITC
Lokale Artikelnummer::
BOSSBS-4989R-FITC
Beschreibung:
During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including long-term potentiation (LTP), long-term depression (LTD), certain forms of short-term synaptic plasticity, as well as homeostatic regulation of intrinsic neuronal excitability.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9652R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9652R-A680
Lokale Artikelnummer::
BOSSBS-9652R-A680
Beschreibung:
Functions as a negative regulator of TGF-beta Signalling and thereby probably plays a role in cell proliferation, differentiation, apoptosis, motility, extracellular matrix production and immunosuppression. In the canonical TGF-beta pathway, ZFYVE9/SARA recruits the intracellular signal transducer and transcriptional modulators SMAD2 and SMAD3 to the TGF-beta receptor. Phosphorylated by the receptor, SMAD2 and SMAD3 then form a heteromeric complex with SMAD4 that translocates to the nucleus to regulate transcription. Through interaction with SMAD2 and SMAD3, LDLRAD4 may compete with ZFYVE9 and SMAD4 and prevent propagation of the intracellular signal.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5983R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5983R-A750
Lokale Artikelnummer::
BOSSBS-5983R-A750
Beschreibung:
AARE (Acylamino-acid-releasing enzyme) is also known as Acyl-peptide hydrolase. It catalyzes the hydrolysis of the terminal acetylated amino acid preferentially from small acetylated peptides. The acetyl amino acid formed by this hydrolase is further processed to acetate and a free amino acid by an aminoacylase. It can play an important role in destroying oxidatively damaged proteins in living cells. Deletions of this gene locus corresponding to the protein are found in various types of carcinomas, including small cell lung carcinoma and renal cell carcinoma.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-4989R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4989R-HRP
Lokale Artikelnummer::
BOSSBS-4989R-HRP
Beschreibung:
During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including long-term potentiation (LTP), long-term depression (LTD), certain forms of short-term synaptic plasticity, as well as homeostatic regulation of intrinsic neuronal excitability.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6516R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6516R-A555
Lokale Artikelnummer::
BOSSBS-6516R-A555
Beschreibung:
The protein encoded by this gene was initially named CA-related protein because of sequence similarity to other known carbonic anhydrase genes. However, the gene product lacks carbonic anhydrase activity (i.e., the reversible hydration of carbon dioxide). The gene product continues to carry a carbonic anhydrase designation based on clear sequence identity to other members of the carbonic anhydrase gene family. The absence of CA8 gene transcription in the cerebellum of the lurcher mutant in mice with a neurologic defect suggests an important role for this acatalytic form.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3521R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3521R-A647
Lokale Artikelnummer::
BOSSBS-3521R-A647
Beschreibung:
This gene encodes a member of the Polycomb-group (PcG) family. PcG family members form multimeric protein complexes, which are involved in maintaining the transcriptional repressive state of genes over successive cell generations. This protein associates with the embryonic ectoderm development protein, the VAV1 oncoprotein, and the X-linked nuclear protein. This protein may play a role in the hematopoietic and central nervous systems. Multiple alternatively splcied transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Feb 2011].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13258R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13258R-A750
Lokale Artikelnummer::
BOSSBS-13258R-A750
Beschreibung:
The multi-pass membrane protein encoded by this gene belongs to the G-protein coupled receptor 3 family and GABA-B receptor subfamily. The GABA-B receptors inhibit neuronal activity through G protein-coupled second-messenger systems, which regulate the release of neurotransmitters, and the activity of ion channels and adenylyl cyclase. This receptor subunit forms an active heterodimeric complex with GABA-B receptor subunit 1, neither of which is effective on its own. Allelic variants of this gene have been associated with nicotine dependence.[provided by RefSeq, Jan 2010].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-6127R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6127R
Lokale Artikelnummer::
BOSSBS-6127R
Beschreibung:
Catalyzes the specific attachment of an amino acid to its cognate tRNA in a 2 step reaction: the amino acid (AA) is first activated by ATP to form AA-AMP and then transferred to the acceptor end of the tRNA. When secreted, acts as a signaling molecule that induces immune response through the activation of monocyte/macrophages. Catalyzes the synthesis of diadenosine oligophosphate (Ap4A), a signaling molecule involved in the activation of MITF transcriptional activity. Interacts with HIV-1 virus GAG protein, facilitating the selective packaging of tRNA(3)(Lys), the primer for reverse transcription initiation.
VE:
1 * 100 µl
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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