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1,1-Diphenylhydrazin+Hydrochlorid
Artikel-Nr:
(BOSSBS-8098R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8098R-FITC
Lokale Artikelnummer::
BOSSBS-8098R-FITC
Beschreibung:
The coiled-coil domain is a structural motif found in proteins that are involved in a diverse array of biological functions such as the regulation of gene expression, cell division, membrane fusion and drug extrusion and delivery. CCDC34 (coiled-coil domain containing 34), also known as Renal carcinoma antigen NY-REN-41, is a 373 amino acid protein that is expressed in testis, breast, lung, placenta, liver and small intestine. A translocation between the short arms of chromosomes 11 and 18 affecting the CCDC34 gene has been identified in a patient with hamartoma of the retinal pigment epithelium. There are two isoforms of CCDC34 that are produced as a result of alternative splicing events.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-10465R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-10465R-A680
Lokale Artikelnummer::
BOSSBS-10465R-A680
Beschreibung:
Alpha-1-adrenergic receptors (alpha-1-ARs) are members of the G protein-coupled receptor superfamily. They activate mitogenic responses and regulate growth and proliferation of many cells. There are 3 alpha-1-AR subtypes: alpha-1A, -1B and -1D, all of which signal through the Gq/11 family of G-proteins and different subtypes show different patterns of activation. This gene encodes alpha-1B-adrenergic receptor, which induces neoplastic transformation when transfected into NIH 3T3 fibroblasts and other cell lines. Thus, this normal cellular gene is identified as a protooncogene. This gene comprises 2 exons and a single large intron of at least 20 kb that interrupts the coding region.
VE:
1 * 100 µl
Lieferant:
Thermo Scientific
Beschreibung:
m-Tolylhydraziniumchlorid
Artikel-Nr:
(BOSSBS-12338R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12338R-A680
Lokale Artikelnummer::
BOSSBS-12338R-A680
Beschreibung:
Carboxypeptidase A (CPA) is a pancreatic exopeptidase which hydrolyses the peptide bond adjacent to the C-terminal end in polypeptide chains. Mast cell carboxypeptidase A (MC-CPA), a part of the peptidase M14 family, is a highly conserved metalloprotease localised to the secretory granules, along with trytases and chymases. MC-CPA is stored as an active enzyme in the granule and is released, along with other inflammatory mediators, upon mast cell degranulation. MC-CPA mirrors pancreatic carboxypeptidase A in cleaving COOH-terminal aromatic and aliphatic amino acid residues. The optimum pH of MC-CPA is between neutral and basic, depending upon the substrate. The MC-CPA gene, CPA3, resides on chromosome 3 and contains 11 exons.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11544R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11544R-A750
Lokale Artikelnummer::
BOSSBS-11544R-A750
Beschreibung:
Bcl-11a genes play crucial roles in lymphopoiesis and influence the progression of hematopoietic malignancies. Disruption of the Bcl-11b locus is linked to T cell acute lymphoblastic leukaemia, and the loss of heterozygosity in mice results in T cell lymphoma. Bcl-11 proteins are related C2H2 zinc-finger transcription factors that act as transcriptional repressors. Bcl-11b can interact with the metastasis-associated proteins MTA1 and MTA2 through the amino-terminal region. Bcl-11a is essential for postnatal development and normal lymphopoiesis. The Bcl-11a mouse gene is a common site of retroviral integration in myeloid leukaemia, and may function as a leukaemia disease gene, in part, through its interaction with Bcl-6.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-10465R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-10465R-HRP
Lokale Artikelnummer::
BOSSBS-10465R-HRP
Beschreibung:
Alpha-1-adrenergic receptors (alpha-1-ARs) are members of the G protein-coupled receptor superfamily. They activate mitogenic responses and regulate growth and proliferation of many cells. There are 3 alpha-1-AR subtypes: alpha-1A, -1B and -1D, all of which signal through the Gq/11 family of G-proteins and different subtypes show different patterns of activation. This gene encodes alpha-1B-adrenergic receptor, which induces neoplastic transformation when transfected into NIH 3T3 fibroblasts and other cell lines. Thus, this normal cellular gene is identified as a protooncogene. This gene comprises 2 exons and a single large intron of at least 20 kb that interrupts the coding region. [provided by RefSeq, Jul 2008].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11544R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11544R-A680
Lokale Artikelnummer::
BOSSBS-11544R-A680
Beschreibung:
Bcl-11a genes play crucial roles in lymphopoiesis and influence the progression of hematopoietic malignancies. Disruption of the Bcl-11b locus is linked to T cell acute lymphoblastic leukaemia, and the loss of heterozygosity in mice results in T cell lymphoma. Bcl-11 proteins are related C2H2 zinc-finger transcription factors that act as transcriptional repressors. Bcl-11b can interact with the metastasis-associated proteins MTA1 and MTA2 through the amino-terminal region. Bcl-11a is essential for postnatal development and normal lymphopoiesis. The Bcl-11a mouse gene is a common site of retroviral integration in myeloid leukaemia, and may function as a leukaemia disease gene, in part, through its interaction with Bcl-6.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11690R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11690R-A350
Lokale Artikelnummer::
BOSSBS-11690R-A350
Beschreibung:
FIG4 is a 907 amino acid protein that contains one SAC domain through which it is thought to function as a phosphoinositide phosphatase that may play an important role in signal transduction and vesicle trafficking. Defects in the gene encoding FIG4 are the cause of Charcot-Marie-Tooth disease type 4J (CMT4J) and amyotrophic lateral sclerosis type 11 (ALS11), both of which negatively affect the nervous system. CMT4J is a recessive demyelinating disorder of the peripheral nervous system and is characterized by reduced motor nerve conduction velocities and axonal degeneration. Unlike CMT4J, ALS11 is characterized by the degeneration of upper motor neurons in the brain and lower neurons in the spinal cord, causing paralysis and, ultimately, death.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11390R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11390R-FITC
Lokale Artikelnummer::
BOSSBS-11390R-FITC
Beschreibung:
AASDHPPT (aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase), also known as LYS2, LYS5 or CGI-80, is a 309 amino acid protein that localizes to the cytoplasm and belongs to the P-Pant transferase superfamily. Expressed in testis, liver, kidney, heart, brain, placenta and skeletal muscle, AASDHPPT exists as a monomer that functions to catalyze the phosphopantetheine-dependent post-translational modification of target proteins, effectively transferring a 4'-phosphopantetheine moiety from coenzyme A (CoA) to a serine residue of an acceptor protein. AASDHPPT is subject to DNA damage-dependent phosphorylation, probably by ATM or ATR. The gene encoding AASDHPPT maps to human chromosome 11, which houses over 1,400 genes and comprises nearly 4% of the human genome.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11544R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11544R-A488
Lokale Artikelnummer::
BOSSBS-11544R-A488
Beschreibung:
Bcl-11a genes play crucial roles in lymphopoiesis and influence the progression of hematopoietic malignancies. Disruption of the Bcl-11b locus is linked to T cell acute lymphoblastic leukemia, and the loss of heterozygosity in mice results in T cell lymphoma. Bcl-11 proteins are related C2H2 zinc-finger transcription factors that act as transcriptional repressors. Bcl-11b can interact with the metastasis-associated proteins MTA1 and MTA2 through the amino-terminal region. Bcl-11a is essential for postnatal development and normal lymphopoiesis. The Bcl-11a mouse gene is a common site of retroviral integration in myeloid leukemia, and may function as a leukemia disease gene, in part, through its interaction with Bcl-6.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11544R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11544R-CY5
Lokale Artikelnummer::
BOSSBS-11544R-CY5
Beschreibung:
Bcl-11a genes play crucial roles in lymphopoiesis and influence the progression of hematopoietic malignancies. Disruption of the Bcl-11b locus is linked to T cell acute lymphoblastic leukemia, and the loss of heterozygosity in mice results in T cell lymphoma. Bcl-11 proteins are related C2H2 zinc-finger transcription factors that act as transcriptional repressors. Bcl-11b can interact with the metastasis-associated proteins MTA1 and MTA2 through the amino-terminal region. Bcl-11a is essential for postnatal development and normal lymphopoiesis. The Bcl-11a mouse gene is a common site of retroviral integration in myeloid leukemia, and may function as a leukemia disease gene, in part, through its interaction with Bcl-6.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11690R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11690R-CY3
Lokale Artikelnummer::
BOSSBS-11690R-CY3
Beschreibung:
FIG4 is a 907 amino acid protein that contains one SAC domain through which it is thought to function as a phosphoinositide phosphatase that may play an important role in signal transduction and vesicle trafficking. Defects in the gene encoding FIG4 are the cause of Charcot-Marie-Tooth disease type 4J (CMT4J) and amyotrophic lateral sclerosis type 11 (ALS11), both of which negatively affect the nervous system. CMT4J is a recessive demyelinating disorder of the peripheral nervous system and is characterized by reduced motor nerve conduction velocities and axonal degeneration. Unlike CMT4J, ALS11 is characterized by the degeneration of upper motor neurons in the brain and lower neurons in the spinal cord, causing paralysis and, ultimately, death.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8672R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8672R
Lokale Artikelnummer::
BOSSBS-8672R
Beschreibung:
HDL is a cholesterol carrier protein that acts as scavenger of tissue cholesterol. It is important in cholesterol efflux from tissues, and involved in the return of cholesterol from the periphery to the liver for removal as bile acids.This gene encodes apolipoprotein A-I, which is the major protein component of high density lipoprotein (HDL) in plasma. The protein promotes cholesterol efflux from tissues to the liver for excretion, and it is a cofactor for lecithin cholesterolacyltransferase (LCAT) which is responsible for the formation of most plasma cholesteryl esters. This gene is closely linked with two other apolipoprotein genes on chromosome 11. Defects in this gene are associated with HDL deficiencies, including Tangier disease, and with systemic non-neuropathic amyloidosis. [provided by RefSeq, Jul 2008].
VE:
1 * 100 µl
Lieferant:
Biotium
Beschreibung:
Recognizes a protein of 36 kDa, identified as cyclin D1. Cyclin D1, one of the key cell cycle regulators, is a putative proto-oncogene overexpressed in a wide variety of human neoplasms. This antibody neutralizes the activity of cyclin D1 in vivo. About 60% of mantle cell lymphomas (MCL) contain a t(11; 14)(q13; q32) translocation resulting in over-expression of cyclin D1. This antibody is useful in identifying mantle cell lymphomas (cyclin D1 positive) from CLL/SLL and follicular lymphomas (cyclin D1 negative). About 40% of breast carcinomas are positive for Cyclin D1. Occasionally, hairy cell leukemia and plasma cell myeloma weakly express Cyclin D1.
Lieferant:
Biotium
Beschreibung:
Recognizes a protein of 50-65 kDa, identified as CD16 (Workshop IV; Code N39 ) (also known low affinity Fc receptor III for IgG (FcRIII) or Leu 11). CD16 exists as a polypepetide-anchored from (FCRIIIA or CD16A) on human natural killer (NK) cells and monocytes/ macrophages and as a glycosylphosphatidylinositol (GPI)-anchored form (FcRIIIB or CD16B) on neutrophils. CD16B is polymorphic and the two alleles are termed NA1 and NA2.3 CD16 plays a role in signal transduction, NK cell activation and antibody-dependent cellular cytotoxicity. This MAb has been showed to inhibit the binding of immune complex to NK cells, inhibit cytotoxicity of NK cells, and induce calcium fluxes in NK cells and neutrophils.
Artikel-Nr:
(EDQMA0360000)
Lieferant:
EDQM
Hersteller-Artikelnummer::
A0360000
Lokale Artikelnummer::
EDQMA0360000
Beschreibung:
Organic Standard, Alprenolol hydrochloride, Ph. Eur. standard, Packung: Vial
VE:
1 * 100 mg
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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