Artikel-Nr:
(BOSSBS-4817R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4817R-A750
Lokale Artikelnummer::
BOSSBS-4817R-A750
Beschreibung:
Accessory protein for MHC class-II antigen/T-cell receptor interaction. May regulate T-cell activation. Induces the aggregation of lipid rafts.
VE:
1 * 100 µl
Lieferant:
Alfa Aesar
Beschreibung:
Bariumcarbonat ≥99%
Lieferant:
Biotium
Beschreibung:
Recognizes a 77-85 kDa protein, identified as cellular or tissue transglutaminase II (TGase II). Transglutaminases are enzymes that catalyze the crosslinking of proteins by epsilon-gamma glutamyl lysine isopeptide bonds. While the primary structure of transglutaminases is not conserved, they all have the same amino acid sequence at their active sites and their activity is calcium-dependent. The protein encoded by this gene acts as a monomer, is induced by retinoic acid, and appears to be involved in apoptosis. Finally, the encoded protein is the autoantigen implicated in celiac disease. The identification of transglutaminase as the main antigen of endomysium antibodies allows a new diagnostic approach to celiac disease (CD), a genetic, immunologically mediated small bowel enteropathy that causes malabsorption. TGase II is implicated in programmed cell death, signal transduction, drug-resistance, cell growth, endocytosis, insulin secretion, cell adhesion, cataract formation, and wound healing.
Artikel-Nr:
(BTIUBNUM0419-50)
Lieferant:
Biotium
Hersteller-Artikelnummer::
BNUM0419-50
Lokale Artikelnummer::
BTIUBNUM0419-50
Beschreibung:
Recognizes a 77-85 kDa protein, identified as cellular or tissue transglutaminase II (TGase II). Transglutaminases are enzymes that catalyze the crosslinking of proteins by epsilon-gamma glutamyl lysine isopeptide bonds. While the primary structure of transglutaminases is not conserved, they all have the same amino acid sequence at their active sites and their activity is calcium-dependent. The protein encoded by this gene acts as a monomer, is induced by retinoic acid, and appears to be involved in apoptosis. Finally, the encoded protein is the autoantigen implicated in celiac disease. The identification of transglutaminase as the main antigen of endomysium antibodies allows a new diagnostic approach to celiac disease (CD), a genetic, immunologically mediated small bowel enteropathy that causes malabsorption. TGase II is implicated in programmed cell death, signal transduction, drug-resistance, cell growth, endocytosis, insulin secretion, cell adhesion, cataract formation, and wound healing.
VE:
1 * 50 µl
Artikel-Nr:
(BOSSBS-5968R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5968R-CY5
Lokale Artikelnummer::
BOSSBS-5968R-CY5
Beschreibung:
Component of the little elongation complex (LEC), a complex required to regulate small nuclear RNA (snRNA) gene transcription by RNA polymerase II and III.
VE:
1 * 100 µl
Lieferant:
Sartorius Balances
Beschreibung:
Cubis® II MCE micro balances with essential user interface offer readability of 1 μg and a maximum capacity between 3,1 and 10,1 g. Used to determine the exact weight of very small sample quantities.
Lieferant:
Tonbo Biosciences
Beschreibung:
The RM4-5 antibody reacts with mouse CD4, a 55 kDa protein which acts as a co-receptor for the T cell receptor (TCR) in its interaction with MHC Class II molecules on antigen-presenting cells. The extracellular domain of CD4 binds to the beta2-domain of MHC Class II, while its cytoplasmic tail provides a binding site for the tyrosine kinase lck, facilitating the signaling cascade that initiates T cell activation. CD4 is typically expressed on thymocytes, certain mature T cell populations such as Th17 and T regulatory (Treg) cells, as well as on dendritic cells.
Artikel-Nr:
(BOSSBS-8530R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8530R-CY7
Lokale Artikelnummer::
BOSSBS-8530R-CY7
Beschreibung:
Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3971R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3971R-CY5
Lokale Artikelnummer::
BOSSBS-3971R-CY5
Beschreibung:
Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).
VE:
1 * 100 µl
Lieferant:
Alfa Aesar
Beschreibung:
Mangandinatrium-EDTA-Hydrat
Lieferant:
Sartorius Balances
Beschreibung:
Cubis® II MCA analytical balances with advanced user interface offer maximum weighing capacity between 120 and 520 g in combination with readability of 0.1 mg.
Artikel-Nr:
(BOSSBS-2133R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2133R-A555
Lokale Artikelnummer::
BOSSBS-2133R-A555
Beschreibung:
Receptor for angiotensin II. Cooperates with MTUS1 to inhibit ERK2 activation and cell proliferation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2133R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2133R-A350
Lokale Artikelnummer::
BOSSBS-2133R-A350
Beschreibung:
Receptor for angiotensin II. Cooperates with MTUS1 to inhibit ERK2 activation and cell proliferation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3992R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3992R
Lokale Artikelnummer::
BOSSBS-3992R
Beschreibung:
The hexokinases utilize Mg-ATP as a phosphoryl donor to catalyze the first step of intracellular glucose metabolism, the conversion of glucose to glucose-6-phosphate. Four hexokinase isoenzymes have been identified, including hexokinase I (HXK I), hexokinase II (HXK II), hexokinase III (HXK III) and hexokinase IV (HXK IV, also designated glucokinase or GCK). Hexokinases I-III each contain an N-terminal cluster of hydrophobic amino acids. Glucokinase lacks the N-terminal hydrophobic cluster. The hydrophobic cluster is thought to be necessary for membrane binding. This is substantiated by the finding that glucokinase has lower affinity for glucose than do the other hexokinases. HXK I has been shown to be expressed in brain, kidney and heart tissues as well as in hepatoma cell lines. HXK II is involved in the uptake and utilization of glucose by adipose and skeletal tissues. Of the hexokinases, HXK III has the highest affinity for glucose. Glucokinase is expressed in pancreatic beta cells where it functions as a glucose sensor, determining the “set point†for insulin secretion.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0647R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0647R-CY7
Lokale Artikelnummer::
BOSSBS-0647R-CY7
Beschreibung:
Accessory protein for MHC class-II antigen/T-cell receptor interaction. May regulate T-cell activation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0647R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0647R-CY3
Lokale Artikelnummer::
BOSSBS-0647R-CY3
Beschreibung:
Accessory protein for MHC class-II antigen/T-cell receptor interaction. May regulate T-cell activation.
VE:
1 * 100 µl
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