1,2-Phenylendiisothiocyanat
Artikel-Nr:
(BOSSBS-15154R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-15154R-A750
Lokale Artikelnummer::
BOSSBS-15154R-A750
Beschreibung:
C12orf56 (chromosome 12 open reading frame 56), also known as PRO1853 or protein midA homolog, is a 441 amino acid mitochondrial protein that belongs to the midA family. Existing as two alternatively spliced isoforms, C12orf56 is encoded by a gene that maps to human chromosome 2p22.2. As the second largest human chromosome, chromosome 2 makes up approximately 8% of the human genome and contains 237 million bases encoding over 1,400 genes. A number of genetic diseases are linked to genes on chromosome 2. Harlequin icthyosis, a rare skin deformity, is associated with mutations in the ABCA12 gene. The lipid metabolic disorder sitosterolemia is associated with ABCG5 and ABCG8. An extremely rare recessive genetic disorder, Alstr syndrome, is related to mutations in the ALMS1 gene. Chromosome 2 contains a probable vestigial second centromere as well as vestigial telomeres, which gives credence to the hypothesis that human chromosome 2 formed as a result of an ancient fusion of two ancestral chromosomes, which are still present in modern day apes.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-15154R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-15154R-A555
Lokale Artikelnummer::
BOSSBS-15154R-A555
Beschreibung:
C12orf56 (chromosome 12 open reading frame 56), also known as PRO1853 or protein midA homolog, is a 441 amino acid mitochondrial protein that belongs to the midA family. Existing as two alternatively spliced isoforms, C12orf56 is encoded by a gene that maps to human chromosome 2p22.2. As the second largest human chromosome, chromosome 2 makes up approximately 8% of the human genome and contains 237 million bases encoding over 1,400 genes. A number of genetic diseases are linked to genes on chromosome 2. Harlequin icthyosis, a rare skin deformity, is associated with mutations in the ABCA12 gene. The lipid metabolic disorder sitosterolemia is associated with ABCG5 and ABCG8. An extremely rare recessive genetic disorder, Alstr syndrome, is related to mutations in the ALMS1 gene. Chromosome 2 contains a probable vestigial second centromere as well as vestigial telomeres, which gives credence to the hypothesis that human chromosome 2 formed as a result of an ancient fusion of two ancestral chromosomes, which are still present in modern day apes.
VE:
1 * 100 µl
Lieferant:
Sigma-Aldrich
Beschreibung:
1,3-Propansulton, Sigma-Aldrich®
Artikel-Nr:
(DELT901407)
Lieferant:
DELTALAB
Hersteller-Artikelnummer::
901407
Lokale Artikelnummer::
DELT901407
Beschreibung:
Polystyrene, flexible, white
VE:
1 * 25 ST
Artikel-Nr:
(VITL90794)
Lieferant:
VITLAB
Hersteller-Artikelnummer::
90794
Lokale Artikelnummer::
VITL90794
Beschreibung:
Stopper for Standard Ground Joints, PP, square-knob cap, NS: 12/21, Weiß/rot
VE:
1 * 10 ST
Lieferant:
KARTELL
Beschreibung:
PP, durchscheinend.
Artikel-Nr:
(HECH40958016)
Lieferant:
GLASWARENFABRIK KARL HECHT
Hersteller-Artikelnummer::
40958016
Lokale Artikelnummer::
HECH40958016
Beschreibung:
Borosilicate glass 3.3.
VE:
1 * 100 ST
Artikel-Nr:
(MOLEM19265187)
Lieferant:
Molekula
Hersteller-Artikelnummer::
M19265187
Lokale Artikelnummer::
MOLEM19265187
Beschreibung:
4-Nitro-o-xylol
VE:
1 * 100 g
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Artikel-Nr:
(L16588.06)
Lieferant:
Alfa Aesar
Hersteller-Artikelnummer::
L16588.06
Lokale Artikelnummer::
ALFAL16588.06
Beschreibung:
1H,1H,12H,12H-Eicosafluor-1,12-dodecandiol tech. 90%, technische Qualität
VE:
1 * 5 g
Artikel-Nr:
(CONSSP21X)
Lieferant:
CONSORT
Hersteller-Artikelnummer::
SP21X
Lokale Artikelnummer::
CONSSP21X
Beschreibung:
Elektrode, pH, SP21X, pH: 0 - 14, 0...+100 °C, Glas, Membran: Single junction, Elektrolyt: Refillable, Ø×L: 12×110 mm, S7, Für: General purposes
VE:
1 * 1 ST
Lieferant:
KARTELL
Beschreibung:
PS or PP.
Artikel-Nr:
(221-0096)
Lieferant:
Thermo Fisher Scientific
Hersteller-Artikelnummer::
4260-0040
Lokale Artikelnummer::
NALG4260-0040
Beschreibung:
LDPE, durchscheinend.
VE:
1 * 2 ST
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Artikel-Nr:
(BOSSBS-12332R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12332R-A350
Lokale Artikelnummer::
BOSSBS-12332R-A350
Beschreibung:
Dyrk is the homolog of the Drosophila mnb (minibrain) gene, which is required for neurogenesis (1–3). Dyrk is a dual-specificity tyrosine kinase and serine/threonine kinase, which is itself regulated by tyrosine phosphorylation (1). Several mammalian Dyrk related proteins have been identified and are thought to compose a family of dual specificity protein kinases (4). Dyrk family members, including Dyrk1A (originally Dyrk), Dyrk1B, Dryk1C, Dyrk2, Dyrk3, Dyrk4A and Dyrk4B, are thought to be involved in diverse cellular functions (4). Dyrk1A is a candidate gene that may be involved in Downs syndrome, and it has been found to be somewhat overexpressed in Downs syndrome (1,5). Two isoforms of human fetal brain Dyrk2 exist: a deduced 528-amino acid protein and a protein containing 73 additional amino acids at the amino terminus (4). Dyrk3 is strongly expressed in testis, only after the onset of spermatogenesis, and very weakly expressed in spleen and adrenal gland (1). The genes which encode Dyrk2 and Dyrk3 map to human chromosomes 12 and 1q32, respectively (4).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11769R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11769R-A488
Lokale Artikelnummer::
BOSSBS-11769R-A488
Beschreibung:
The majority of mitochondrial-directed proteins are encoded by the nuclear genome and are transported to the mitochondria via regulated processes involving the mitochondrial Tom and Tim proteins (1). The mitochondrial Tim protein family is comprised of a large group of evolutionarily conserved proteins that are found in most eukaryotes (1,2). Import of nuclear-encoded precursor proteins into and across the mitochondrial inner membrane is mediated by two distinct complexes, the Tim23 complex and the Tim22 complex, which differ in their substrate specificity (1). Defects in Tim proteins are implicated in several neuro-degenerative diseases, suggesting important roles for Tim proteins in development and health (3,4). Tim8A and Tim8B, which map to human chromosomes Xq22.1 and 11q23.1-q23.2, respectively, are conserved proteins of the mitochondrial intermembrane space, which are organized in hetero-oligomeric complex with Tim13 (5,6,7). Tim8A is highly expressed in fetal and adult brain (5). Tim8A is mutated in deafness dystonia syndrome, a novel type of disease that causes severe neurological defects, thought to be caused by a defective mitochondrial protein transport system (5,8).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11512R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11512R-A350
Lokale Artikelnummer::
BOSSBS-11512R-A350
Beschreibung:
Bardet-Biedl syndrome (BBS) is a pleiotropic genetic disorder characterized by obesity, photoreceptor degeneration, polydactyly, hypogenitalism, renal abnormalities, and developmental delay. Other associated clinical findings in BBS patients include diabetes, hypertension, and congenital heart defects. BBS genes map to multiple loci and encode fourteen proteins, BBS1-BBS14. Many BBS genes encode basal body or cilia proteins, suggesting that BBS is a ciliary dysfunction disorder. BBS10 (Bardet-Biedl syndrome 10), also known as chromosome 12 open reading fame 58, C12orf58 or FLJ23560, is a novel 723 amino acid protein belonging to the TCP-1 chaperonin family. BBS10 localizes to the basal body of primary cilium and assists in protein folding upon ATP hydrolysis. Inhibition of BBS10 has been found to impair ciliogenesis, activate the glycogen synthase kinase 3 pathway and cause peroxisome proliferator-activated receptor nuclear accumulation. The gene encoding BBS10 contains two exons and maps to human chromosome 12q21.2.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11512R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11512R-A680
Lokale Artikelnummer::
BOSSBS-11512R-A680
Beschreibung:
Bardet-Biedl syndrome (BBS) is a pleiotropic genetic disorder characterised by obesity, photoreceptor degeneration, polydactyly, hypogenitalism, renal abnormalities, and developmental delay. Other associated clinical findings in BBS patients include diabetes, hypertension, and congenital heart defects. BBS genes map to multiple loci and encode fourteen proteins, BBS1-BBS14. Many BBS genes encode basal body or cilia proteins, suggesting that BBS is a ciliary dysfunction disorder. BBS10 (Bardet-Biedl syndrome 10), also known as chromosome 12 open reading fame 58, C12orf58 or FLJ23560, is a novel 723 amino acid protein belonging to the TCP-1 chaperonin family. BBS10 localizes to the basal body of primary cilium and assists in protein folding upon ATP hydrolysis. Inhibition of BBS10 has been found to impair ciliogenesis, activate the glycogen synthase kinase 3 pathway and cause peroxisome proliferator-activated receptor nuclear accumulation. The gene encoding BBS10 contains two exons and maps to human chromosome 12q21.2.
VE:
1 * 100 µl
Preis auf Anfrage
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