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1,2-Phenylendiisothiocyanat
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1,2-Phenylendiisothiocyanat
Artikel-Nr:
(PRSI7615)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
7615
Lokale Artikelnummer::
PRSI7615
Beschreibung:
TMIGD1 (transmembrane and immunoglobulin domain containing 1) is a 262 amino acid single-pass membrane protein that contains two Ig-like C2-type (immunoglobulin-like) domains (1,2). It is a nonsecreted, glycosylated protein located in the cytoplasm and cell membrane. TMIGD1 might be a possible cell-differentiation marker in the intestine, whose expression is lost during cellular transformation and promote progression of tumorigenesis in the intestinal epithelium. TMIGD1 has also been postulated to play a role in cell adhesion.
VE:
1 * 100 µG
Artikel-Nr:
(APOSOR89372-100MG)
Lieferant:
APOLLO SCIENTIFIC
Hersteller-Artikelnummer::
OR89372-100MG
Lokale Artikelnummer::
APOSOR89372-100MG
Beschreibung:
1-Hydroxy-3,3-dimethyl-1,3-dihydrobenzo[c][1,2]oxaborole-5-carboxylic acid 100mg pack 1 * 100 mg
VE:
1 * 100 mg
New Product
Artikel-Nr:
(APOSOR89372-50MG)
Lieferant:
APOLLO SCIENTIFIC
Hersteller-Artikelnummer::
OR89372-50MG
Lokale Artikelnummer::
APOSOR89372-50MG
Beschreibung:
1-Hydroxy-3,3-dimethyl-1,3-dihydrobenzo[c][1,2]oxaborole-5-carboxylic acid 50mg pack 1 * 50 mg
VE:
1 * 50 mg
New Product
Artikel-Nr:
(BOSSBS-5372R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5372R
Lokale Artikelnummer::
BOSSBS-5372R
Beschreibung:
Heterotrimeric G protein-mediated signal transduction is a dynamically regulated process with the intensity of signal decreasing over time despite the continued presence of the agonist (1,2). G protein-coupled receptor kinases (GRKs) are activated by activated G protein-coupled receptors, and they function to phosphorylate and inactivate cell surface receptors in the heterotrimeric G protein signaling cascade (3,4). GIT1 (for GRK-interactor 1) and GIT2 are GTPase-activating proteins (GAP) for members of the ADP ribosylation factor (ARF) family of small GTP-binding proteins, which are involved in vesicular trafficking (5,6). GIT1 overexpression results in reduced internalization and resensitization of b2-adrenergic receptor, thus reducing b2-adrenergic receptor signaling (5).
VE:
1 * 100 µl
Artikel-Nr:
(PRSI7643)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
7643
Lokale Artikelnummer::
PRSI7643
Beschreibung:
Arrestin 3 (ARR3) belongs to the Arrestin family of proteins that function as negative regulators of G protein-coupled receptor (GPCR) signaling (1,2). ARR3 binds the c-Jun N-terminal kinase 3 (JNK3) and scaffolds the apoptosis signal-regulating kinase 1 (ASK1)-MAPK kinase4-JNK3 cascade in a receptor-independent fashion, promoting JNK3 phosphorylation. ARR3 also mediates the internalization of the C-C chemokine receptor CCR7 upon the binding of its ligand CCL19, but not CCL21, suggesting that it helps mediate CCR7 receptor desensitization.
VE:
1 * 100 µG
Artikel-Nr:
(BOSSBS-12210R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12210R-CY3
Lokale Artikelnummer::
BOSSBS-12210R-CY3
Beschreibung:
Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Krüppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. ZNF81, also known as HFZ20 or MRX45, is a transcriptional regulator belonging to the Krüppel C2H2-type zinc-finger protein family. It localizes to the nucleus and contains 12 C2H2-type zinc fingers and 1 KRAB domain. Mutations in the gene encoding ZNF81 are implicated in nonsyndromic X-linked mental retardation (XLMR).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5373R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5373R-A488
Lokale Artikelnummer::
BOSSBS-5373R-A488
Beschreibung:
Heterotrimeric G protein-mediated signal transduction is a dynamically regulated process with the intensity of signal decreasing over time despite the continued presence of the agonist (1,2). G protein-coupled receptor kinases (GRKs) are activated by activated G protein-coupled receptors, and they function to phosphorylate and inactivate cell surface receptors in the heterotrimeric G protein signaling cascade (3,4). GIT1 (for GRK-interactor 1) and GIT2 are GTPase-activating proteins (GAP) for members of the ADP ribosylation factor (ARF) family of small GTP-binding proteins, which are involved in vesicular trafficking (5,6). GIT1 overexpression results in reduced internalization and resensitization of b2-adrenergic receptor, thus reducing b2-adrenergic receptor signaling (5).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5372R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5372R-CY5.5
Lokale Artikelnummer::
BOSSBS-5372R-CY5.5
Beschreibung:
Heterotrimeric G protein-mediated signal transduction is a dynamically regulated process with the intensity of signal decreasing over time despite the continued presence of the agonist (1,2). G protein-coupled receptor kinases (GRKs) are activated by activated G protein-coupled receptors, and they function to phosphorylate and inactivate cell surface receptors in the heterotrimeric G protein signaling cascade (3,4). GIT1 (for GRK-interactor 1) and GIT2 are GTPase-activating proteins (GAP) for members of the ADP ribosylation factor (ARF) family of small GTP-binding proteins, which are involved in vesicular trafficking (5,6). GIT1 overexpression results in reduced internalization and resensitization of b2-adrenergic receptor, thus reducing b2-adrenergic receptor signaling (5).
VE:
1 * 100 µl
Artikel-Nr:
(PRSI7469)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
7469
Lokale Artikelnummer::
PRSI7469
Beschreibung:
The endoplasmic reticulum (ER) aminopeptidase 2 (ERAP2), a member of the peptidase M1 family, like the related protein ERAP1, plays a central role in peptide trimming, a step required for the generation of most HLA class I-binding peptides (1,2). Like ERAP1, ERAP2 is localized to the lumen of the ER and is thought to associate with ERAP1 as a heterodimer. Both ERAP1 and ERAP2 have been linked to several human diseases ranging from infections to autoimmunity and cancer, and may play a role in the innate immune response .
VE:
1 * 100 µG
Artikel-Nr:
(BOSSBS-3303R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3303R
Lokale Artikelnummer::
BOSSBS-3303R
Beschreibung:
This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. This gene is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor; all three genes may be implicated in the 5-q syndrome. A translocation between chromosomes 5 and 12, that fuses this gene to that of the translocation, ETV6, leukemia gene, results in chronic myeloproliferative disorder with eosinophilia. [provided by RefSeq].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3322R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3322R-CY5.5
Lokale Artikelnummer::
BOSSBS-3322R-CY5.5
Beschreibung:
This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. This gene is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor; all three genes may be implicated in the 5-q syndrome. A translocation between chromosomes 5 and 12, that fuses this gene to that of the translocation, ETV6, leukemia gene, results in chronic myeloproliferative disorder with eosinophilia. [provided by RefSeq].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11271R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11271R-CY3
Lokale Artikelnummer::
BOSSBS-11271R-CY3
Beschreibung:
Hip (HSP70-interacting protein), also known as ST13 (suppression of tumorigenicity protein 13), is one of several co-chaperones that regulate activities of the HSP70 chaperone family (1,2). The homo-oligomeric protein Hip cooperates with HSP70 in protein folding by stabilizing the ADP-bound state of HSP70. Hip directly binds to the ATPase domain of HSP70 when it is converted to the ADP-bound state by proteins of the HSP40 family (3). By collaborating with other positive co-factors such as HSP40 and Hop, or competing with negative co-factors such as Bag1, Hip may facilitate the chaperone function of HSP70 in protein folding and repair, and in controlling the activity of regulatory proteins such as steroid receptors and various regulators of proliferation or apoptosis (4-8).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-5373R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5373R
Lokale Artikelnummer::
BOSSBS-5373R
Beschreibung:
Heterotrimeric G protein-mediated signal transduction is a dynamically regulated process with the intensity of signal decreasing over time despite the continued presence of the agonist (1,2). G protein-coupled receptor kinases (GRKs) are activated by activated G protein-coupled receptors, and they function to phosphorylate and inactivate cell surface receptors in the heterotrimeric G protein signaling cascade (3,4). GIT1 (for GRK-interactor 1) and GIT2 are GTPase-activating proteins (GAP) for members of the ADP ribosylation factor (ARF) family of small GTP-binding proteins, which are involved in vesicular trafficking (5,6). GIT1 overexpression results in reduced internalization and resensitization of b2-adrenergic receptor, thus reducing b2-adrenergic receptor signaling (5).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11287R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11287R-CY5
Lokale Artikelnummer::
BOSSBS-11287R-CY5
Beschreibung:
Lymphotactin is a chemokine-like molecule produced selectively, if not exclusively, by activated CD8+ T cells (1). Lymphotactin is a C-type member of the chemokine superfamily, but retains only the 2nd and 4th of the four cysteine residues conserved in other chemokines (3,4). In normal tissues, lymphotactin is expressed at high levels in spleen, thymus, small intestine, and peripheral blood leukocytes, as well as at low levels in lung, prostate, and ovary (2). Lymphotactin is chemotactic for CD4+ and CD8+ T cells but not for monocytes, and induces a rise in intracellular calcium in peripheral blood lymphocytes (1). The specific receptor for lymphotactin is XCR1, a member of the G protein-coupled receptor family (5). The gene which encodes lymphotactin maps to human chromosome 1q23 (1,2).
VE:
1 * 100 µl
Artikel-Nr:
(91113.001)
Lieferant:
VWR Chemicals
Lokale Artikelnummer::
VWRC91113.001
Beschreibung:
A standard mixture, typically used for food testing, containing the following components: 100 ug/ml each of Azinphos-ethyl [CAS:2642-71-9] ; Azinphos-methyl [CAS:86-50-0] ; Chlorpyrifos [CAS:2921-88-2] ; Chlorpyrifos methyl [CAS:5598-13-0] ; Diazinon [CAS:333-41-5] ; EPN [CAS:2104-64-5] ; Fenitrothion [CAS:122-14-5] ; Isazofos [CAS:42509-80-8] ; Phosalone [CAS:2310-17-0] ; Phosmet [CAS:732-11-6] ; Pirimiphos-ethyl [CAS:23505-41-1] ; Pirimiphos-methyl [CAS:29232-93-7] ; Pyraclofos [CAS:89784-60-1] ; Pyrazophos [CAS:13457-18-6] ; Pyridaphenthion [CAS:119-12-0] ; Quinalphos [CAS:13593-03-8] in Toluene
VE:
1 * 1 mL
Artikel-Nr:
(BOSSBS-13360R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13360R-HRP
Lokale Artikelnummer::
BOSSBS-13360R-HRP
Beschreibung:
Heterotrimeric G protein-mediated signal transduction is a dynamically regulated process with the intensity of signal decreasing over time despite the continued presence of the agonist (1,2). G protein-coupled receptor kinases (GRKs) are activated by activated G protein-coupled receptors, and they function to phosphorylate and inactivate cell surface receptors in the heterotrimeric G protein signaling cascade (3,4). GIT1 (for GRK-interactor 1) and GIT2 are GTPase-activating proteins (GAP) for members of the ADP ribosylation factor (ARF) family of small GTP-binding proteins, which are involved in vesicular trafficking (5,6). GIT1 overexpression results in reduced internalization and resensitization of b2-adrenergic receptor, thus reducing b2-adrenergic receptor signaling (5).
VE:
1 * 100 µl
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Dieses Produkt kann nur an eine Lieferadresse versandt werden die über die entsprechende Lizenzen verfügt. Für weitere Hilfe bitte kontaktieren Sie Ihr VWR Vertriebszentrum.
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