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1,2-Propylendiamin
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1,2-Propylendiamin
Artikel-Nr:
(BOSSBS-5827R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-5827R-HRP
Lokale Artikelnummer::
BOSSBS-5827R-HRP
Beschreibung:
PCDHGB5 is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes.
VE:
1 * 100 µl
Lieferant:
KOEHLER TECHNISCHE PRODUKTEN
Beschreibung:
Made of acrylic, clear.
Artikel-Nr:
(KART1037)
Lieferant:
KARTELL
Hersteller-Artikelnummer::
1037
Lokale Artikelnummer::
KART1037
Beschreibung:
PTFE.
VE:
1 * 10 ST
Artikel-Nr:
(SIAL184829-10G)
Lieferant:
Sigma-Aldrich
Hersteller-Artikelnummer::
184829-10G
Lokale Artikelnummer::
SIAL184829-10G
Beschreibung:
2-(Hydroxymethyl)benzylalkohol, Sigma-Aldrich®
VE:
1 * 10 g
Artikel-Nr:
(BOSSBS-11512R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11512R-CY3
Lokale Artikelnummer::
BOSSBS-11512R-CY3
Beschreibung:
Bardet-Biedl syndrome (BBS) is a pleiotropic genetic disorder characterized by obesity, photoreceptor degeneration, polydactyly, hypogenitalism, renal abnormalities, and developmental delay. Other associated clinical findings in BBS patients include diabetes, hypertension, and congenital heart defects. BBS genes map to multiple loci and encode fourteen proteins, BBS1-BBS14. Many BBS genes encode basal body or cilia proteins, suggesting that BBS is a ciliary dysfunction disorder. BBS10 (Bardet-Biedl syndrome 10), also known as chromosome 12 open reading fame 58, C12orf58 or FLJ23560, is a novel 723 amino acid protein belonging to the TCP-1 chaperonin family. BBS10 localizes to the basal body of primary cilium and assists in protein folding upon ATP hydrolysis. Inhibition of BBS10 has been found to impair ciliogenesis, activate the glycogen synthase kinase 3 pathway and cause peroxisome proliferator-activated receptor nuclear accumulation. The gene encoding BBS10 contains two exons and maps to human chromosome 12q21.2.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3773R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3773R-A750
Lokale Artikelnummer::
BOSSBS-3773R-A750
Beschreibung:
Modulation of the chromatin structure plays an important role in the regulation of transcription in eukaryotes. The nucleosome, made up of four core histone proteins (H2A, H2B, H3 and H4), is the primary building block of chromatin. The N-terminal tail of core histones undergoes different posttranslational modifications including acetylation, phosphorylation and methylation. These modifications occur in response to cell signal stimuli and have a direct effect on gene expression. In most species, the histone H2B is primarily acetylated at lysines 5, 12, 15 and 20. Histone H3 is primarily acetylated at lysines 9, 14, 18 and 23. Acetylation at lysine 9 appears to have a dominant role in histone deposition and chromatin assembly in some organisms. Phosphorylation at Ser10 of histone H3 is tightly correlated with chromosome condensation during both mitosis and meiosis.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12379R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12379R-A750
Lokale Artikelnummer::
BOSSBS-12379R-A750
Beschreibung:
Stanniocalcin 1 (STC1) and stanniocalcin 2 (STC2) are mammalian peptide hormones that were previously considered to be present only in bony fish, where they are involved in calcium homeostasis. STC1 plays a role in calcium and phosphate homoeostasis and is phosphorylated in vitro by protein kinase C, and STC2 is phosphorylated in vitro by casein kinase II (CK2). A human fibrosarcoma cell line, HT1080, expresses both STC1 and STC2 as secreted phosphoproteins in vivo, with STC2 being phosphorylated by an ecto-CK2-like enzyme. STC1 and STC2 have opposite effects on calcium and phosphate homeostasis, namely anti-hypercalcemic and anti-hypocalcemic actions, respectively. STC1 and STC2 are detected in human adrenal tumours, such as pheochromocytoma, differentiated neuroblastoma aldosterone-producing adenoma, and in cultured adrenal tumour cells (rat pheochromocytoma PC-12 cells and human neuroblastoma NB-1 cells).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12379R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12379R-A555
Lokale Artikelnummer::
BOSSBS-12379R-A555
Beschreibung:
Stanniocalcin 1 (STC1) and stanniocalcin 2 (STC2) are mammalian peptide hormones that were previously considered to be present only in bony fish, where they are involved in calcium homeostasis. STC1 plays a role in calcium and phosphate homoeostasis and is phosphorylated in vitro by protein kinase C, and STC2 is phosphorylated in vitro by casein kinase II (CK2). A human fibrosarcoma cell line, HT1080, expresses both STC1 and STC2 as secreted phosphoproteins in vivo, with STC2 being phosphorylated by an ecto-CK2-like enzyme. STC1 and STC2 have opposite effects on calcium and phosphate homeostasis, namely anti-hypercalcemic and anti-hypocalcemic actions, respectively. STC1 and STC2 are detected in human adrenal tumors, such as pheochromocytoma, differentiated neuroblastoma aldosterone-producing adenoma, and in cultured adrenal tumor cells (rat pheochromocytoma PC-12 cells and human neuroblastoma NB-1 cells).
VE:
1 * 100 µl
Lieferant:
HAMILTON BONADUZ
Beschreibung:
Loses Sorbents auf Polymer basis für die Anionaustauch-chromatographie.
Artikel-Nr:
(735-0223)
Lieferant:
Thermo Scientific
Hersteller-Artikelnummer::
150200
Lokale Artikelnummer::
NUNC150200
Beschreibung:
PS, non treated, with lid, sterile.
VE:
1 * 75 ST
Artikel-Nr:
(PROOTRCM216100-250)
Lieferant:
LGC Standards PROMOCHEM
Hersteller-Artikelnummer::
TRCM216100-250
Lokale Artikelnummer::
PROOTRCM216100-250
Beschreibung:
Meloxicam
VE:
1 * 250 mg
Artikel-Nr:
(ABNOMAB4478)
Lieferant:
Abnova
Hersteller-Artikelnummer::
MAB4478
Lokale Artikelnummer::
ABNOMAB4478
Beschreibung:
Mouse monoclonal antibody raised against HLA-DR.
VE:
1 * 100 µl
Lieferant:
BIOLEGEND INC
Beschreibung:
Anti-CD100 (SEMA4D) Rat Monoclonal Antibody [clone: BMA-12] (PE (Phycoerythrin))
Lieferant:
Honeywell Chemicals
Beschreibung:
di-Natriumhydrogenphosphat Dodecahydrat 98,5-101% (Trockenmasse), erfüllt analytische Spezifikationen von BP, Ph. Eur., E339, Fluka™
Artikel-Nr:
(HEWL8010-0153)
Lieferant:
Agilent
Hersteller-Artikelnummer::
8010-0153
Lokale Artikelnummer::
HEWL8010-0153
Beschreibung:
Chromatographie, Crimp neck, 0,80 ml, Borosilikatglas , Braun, Ø×H: 12×32 mm, Flacher Boden, Unsteril, Cap included: Nein
VE:
1 * 1.000 ST
Artikel-Nr:
(BOSSBS-13657R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13657R-A350
Lokale Artikelnummer::
BOSSBS-13657R-A350
Beschreibung:
Tumor necrosis factor (TNF) is a pleiotropic cytokine whose function is mediated through two distinct cell surface receptors (1,2). These receptors, designated TNF-R1 and TNF-R2, are expressed on most cell types (1,3). The majority of TNF functions are primarily mediated through TNF-R1 (1,4). FAN (for factor associated with neutral sphingomyelinase (N-SMase) activation) is an intermediate protein that interacts with TNF-R1 to initiate TNF signaling events. FAN binds to TNF-R1 at the cytoplasmic NSD (N-SMase activating domain), which results in the initiation of the N-SMase pathway (5). N-SMase has been shown to be involved in TNF-induced Raf-1 activation (6). FAN contains four carboxy-terminal WD-repeat domains which appear to be involved in protein-protein interaction. The FAN WD-repeats may mediate the interaction between FAN and TNF-R1 (5).
VE:
1 * 100 µl
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Dieses Produkt kann nur an eine Lieferadresse versandt werden die über die entsprechende Lizenzen verfügt. Für weitere Hilfe bitte kontaktieren Sie Ihr VWR Vertriebszentrum.
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