4-Amino-7-bromo-2-methylquinoline
Lieferant:
WITEG LABORTECHNIK
Beschreibung:
Borosilicate glass 3.3, clear.
Lieferant:
BIOLEGEND INC
Beschreibung:
Anti-CD45 Rat Monoclonal Antibody [clone: I3/2.3] (PerCP (Peridinin-Chlorophyll Protein Complex)/Cy5.5®)
Artikel-Nr:
(BOSSBS-12248R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12248R-HRP
Lokale Artikelnummer::
BOSSBS-12248R-HRP
Beschreibung:
Sorting nexin 1 (SNX1) is a member of a large family of hydrophilic proteins that interact with a variety of receptor types and are involved in intracellular trafficking (1). SNX1 and the related splice variant, SNX1A, bind the epidermal growth factor (EGF) receptor, facilitate its transport to lysosome, and thereby contribute to the degradation of the receptor (2,3). SNX2 and SNX4 share a high degree of amino acid similarity with SNX1, as they all contain a characteristic phox homology (PX) domain (4). These proteins are all partially associated with cellular membranes, and they, likewise, associate with EGF, PDGF and insulin receptor tyrosine kinases (2). These nexins are widely expressed and yet have various tissue distribution patterns. Additionally, the sorting nexins can associate with each other and with a variety of other cellular proteins, suggesting that they exist as part of multisubunit complexes (1,5). The related protein, SNX3, comprises a distinct subgroup of nexins that share less sequence similarity outside of the PX domain and have dramatically different binding affinities for the tyrosine kinase receptors (2,6).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12248R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12248R-CY5
Lokale Artikelnummer::
BOSSBS-12248R-CY5
Beschreibung:
Sorting nexin 1 (SNX1) is a member of a large family of hydrophilic proteins that interact with a variety of receptor types and are involved in intracellular trafficking (1). SNX1 and the related splice variant, SNX1A, bind the epidermal growth factor (EGF) receptor, facilitate its transport to lysosome, and thereby contribute to the degradation of the receptor (2,3). SNX2 and SNX4 share a high degree of amino acid similarity with SNX1, as they all contain a characteristic phox homology (PX) domain (4). These proteins are all partially associated with cellular membranes, and they, likewise, associate with EGF, PDGF and insulin receptor tyrosine kinases (2). These nexins are widely expressed and yet have various tissue distribution patterns. Additionally, the sorting nexins can associate with each other and with a variety of other cellular proteins, suggesting that they exist as part of multisubunit complexes (1,5). The related protein, SNX3, comprises a distinct subgroup of nexins that share less sequence similarity outside of the PX domain and have dramatically different binding affinities for the tyrosine kinase receptors (2,6).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12311R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12311R-A750
Lokale Artikelnummer::
BOSSBS-12311R-A750
Beschreibung:
The leucine-rich (LRR) repeat is a 20 to 30 amino acid motif that forms a hydrophobic å/ horseshoe fold, allowing it to accommodate several leucine residues within a tightly packed core. All LRR repeats contain a variable segment and a highly conserved segment, the latter of which accounts for 11 or 12 residues of the entire LRR motif. The primary function of these motifs is to provide a versatile structural framework to mediate the formation of protein-protein interactions. LRRs are present in a variety of proteins with diverse structure and function, including innate immunity and nervous system development. Several human diseases are associated with mutations in genes encoding LRR-containing proteins. LRRC23 (leucine-rich repeat-containing protein 23), also known as leucine-rich protein B7, is a 343 amino acid protein that contains eight LRR (leucine-rich) repeats and one LRRCT domain. LRRC23 exists as two alternatively spliced isoforms and is encoded by a gene mapping to chromosome 12.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12311R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12311R-A680
Lokale Artikelnummer::
BOSSBS-12311R-A680
Beschreibung:
The leucine-rich (LRR) repeat is a 20 to 30 amino acid motif that forms a hydrophobic å/ horseshoe fold, allowing it to accommodate several leucine residues within a tightly packed core. All LRR repeats contain a variable segment and a highly conserved segment, the latter of which accounts for 11 or 12 residues of the entire LRR motif. The primary function of these motifs is to provide a versatile structural framework to mediate the formation of protein-protein interactions. LRRs are present in a variety of proteins with diverse structure and function, including innate immunity and nervous system development. Several human diseases are associated with mutations in genes encoding LRR-containing proteins. LRRC23 (leucine-rich repeat-containing protein 23), also known as leucine-rich protein B7, is a 343 amino acid protein that contains eight LRR (leucine-rich) repeats and one LRRCT domain. LRRC23 exists as two alternatively spliced isoforms and is encoded by a gene mapping to chromosome 12.
VE:
1 * 100 µl
Artikel-Nr:
(LAUDRKJ009)
Lieferant:
LAUDA
Hersteller-Artikelnummer::
RKJ009
Lokale Artikelnummer::
LAUDRKJ009
Beschreibung:
Insulation tubing for increased insulation.
VE:
1 * 1 m
Lieferant:
UVP ULTRA VIOLET PRODUCTS
Beschreibung:
UV-Lamp, UV-Tischlampe, XX-15M, 15 W, 302 nm, B×T×H: 502×152×108 mm, Gewicht: 2,3 kg
Artikel-Nr:
(SCOT241302105)
Lieferant:
DWK Life Sciences
Hersteller-Artikelnummer::
241302105
Lokale Artikelnummer::
SCOT241302105
Beschreibung:
DURAN®, Borosilikatglas 3.3, klar.
VE:
1 * 1 ST
Lieferant:
BIOLEGEND INC
Beschreibung:
Anti-IL-12/IL-23 p40 Rat Monoclonal Antibody [clone: C17.8] (Ultra-LEAF™)
Artikel-Nr:
(BOSSBS-12248R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12248R-A750
Lokale Artikelnummer::
BOSSBS-12248R-A750
Beschreibung:
Sorting nexin 1 (SNX1) is a member of a large family of hydrophilic proteins that interact with a variety of receptor types and are involved in intracellular trafficking (1). SNX1 and the related splice variant, SNX1A, bind the epidermal growth factor (EGF) receptor, facilitate its transport to lysosome, and thereby contribute to the degradation of the receptor (2,3). SNX2 and SNX4 share a high degree of amino acid similarity with SNX1, as they all contain a characteristic phox homology (PX) domain (4). These proteins are all partially associated with cellular membranes, and they, likewise, associate with EGF, PDGF and insulin receptor tyrosine kinases (2). These nexins are widely expressed and yet have various tissue distribution patterns. Additionally, the sorting nexins can associate with each other and with a variety of other cellular proteins, suggesting that they exist as part of multisubunit complexes (1,5). The related protein, SNX3, comprises a distinct subgroup of nexins that share less sequence similarity outside of the PX domain and have dramatically different binding affinities for the tyrosine kinase receptors (2,6).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11427R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11427R-A555
Lokale Artikelnummer::
BOSSBS-11427R-A555
Beschreibung:
In mammalian cells, transcription is regulated in part by high molecular weight coactivating complexes that mediate signals between transcriptional activators and RNA polymerase (1). These complexes include the SMCC (SRB and MED protein cofactor complex), which consists of various subunits that share homology with several components of the yeast transcriptional mediator complexes, and including the human proteins Srb7, Med6 (also designated DRIP33) and Med7 (also designated DRIP34) (2,3). SMCC associates with the RNAPII (RNA polymerase II) holoenzyme through Srb7 and, in turn, enhances gene-specific activation or repression induced by DNA-binding transcription factors (4). Med6 and Med7, as well as other components of SMCC, associate with coactivator proteins from the TRAP (thyroid hormone receptor-activating protein) complex and DRIP (for vitamin D receptor interacting protein) complex to facilitate steroid receptor dependent transcriptional activation (4,5). Additionally, SMCC associates with PC4 (positive cofactor 4) to repress basal transcription independent of RNAPII activity (6).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11427R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11427R-A488
Lokale Artikelnummer::
BOSSBS-11427R-A488
Beschreibung:
In mammalian cells, transcription is regulated in part by high molecular weight coactivating complexes that mediate signals between transcriptional activators and RNA polymerase (1). These complexes include the SMCC (SRB and MED protein cofactor complex), which consists of various subunits that share homology with several components of the yeast transcriptional mediator complexes, and including the human proteins Srb7, Med6 (also designated DRIP33) and Med7 (also designated DRIP34) (2,3). SMCC associates with the RNAPII (RNA polymerase II) holoenzyme through Srb7 and, in turn, enhances gene-specific activation or repression induced by DNA-binding transcription factors (4). Med6 and Med7, as well as other components of SMCC, associate with coactivator proteins from the TRAP (thyroid hormone receptor-activating protein) complex and DRIP (for vitamin D receptor interacting protein) complex to facilitate steroid receptor dependent transcriptional activation (4,5). Additionally, SMCC associates with PC4 (positive cofactor 4) to repress basal transcription independent of RNAPII activity (6).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12248R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12248R
Lokale Artikelnummer::
BOSSBS-12248R
Beschreibung:
Sorting nexin 1 (SNX1) is a member of a large family of hydrophilic proteins that interact with a variety of receptor types and are involved in intracellular trafficking (1). SNX1 and the related splice variant, SNX1A, bind the epidermal growth factor (EGF) receptor, facilitate its transport to lysosome, and thereby contribute to the degradation of the receptor (2,3). SNX2 and SNX4 share a high degree of amino acid similarity with SNX1, as they all contain a characteristic phox homology (PX) domain (4). These proteins are all partially associated with cellular membranes, and they, likewise, associate with EGF, PDGF and insulin receptor tyrosine kinases (2). These nexins are widely expressed and yet have various tissue distribution patterns. Additionally, the sorting nexins can associate with each other and with a variety of other cellular proteins, suggesting that they exist as part of multisubunit complexes (1,5). The related protein, SNX3, comprises a distinct subgroup of nexins that share less sequence similarity outside of the PX domain and have dramatically different binding affinities for the tyrosine kinase receptors (2,6).
VE:
1 * 100 µl
Artikel-Nr:
(UPST20-265)
Lieferant:
UPSTATE TECHNOLOGY
Hersteller-Artikelnummer::
20-265
Lokale Artikelnummer::
UPST20-265
Beschreibung:
Dithiothreitol (DTT, Cleland's Reagenz) 1 mol/l in wässriger Lösung
VE:
1 * 450 µl
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Artikel-Nr:
(3870-25GM)
Lieferant:
Merck Millipore (Calbiochem)
Hersteller-Artikelnummer::
3870-25GM
Lokale Artikelnummer::
CALB3870-25GM
Beschreibung:
Dithiothreitol (DTT, Cleland's Reagenz) ≥99,4%, OmniPur® Calbiochem®, Millipore®
VE:
1 * 25 g
Preis auf Anfrage
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