1,3-Dimethyluracil
Artikel-Nr:
(BOSSBS-10215R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-10215R-A555
Lokale Artikelnummer::
BOSSBS-10215R-A555
Beschreibung:
Carbohydrate-binding lectin with a preference for chitin. Has no chitinase activity. May play a role in tissue remodeling and in the capacity of cells to respond to and cope with changes in their environment. Plays a role in T-helper cell type 2 (Th2) inflammatory response and IL-13-induced inflammation, regulating allergen sensitization, inflammatory cell apoptosis, dendritic cell accumulation and M2 macrophage differentiation. Facilitates invasion of pathogenic enteric bacteria into colonic mucosa and lymphoid organs. Mediates activation of AKT1 signaling pathway and subsequent IL8 production in colonic epithelial cells. Regulates antibacterial responses in lung by contributing to macrophage bacterial killing, controlling bacterial dissemination and augmenting host tolerance. Also regulates hyperoxia-induced injury, inflammation and epithelial apoptosis in lung.
VE:
1 * 100 µl
Artikel-Nr:
(REST30202)
Lieferant:
Restek
Hersteller-Artikelnummer::
30202
Lokale Artikelnummer::
REST30202
Beschreibung:
Contains 1 ml each of these mixtures: 524 calibration mix #7A, 524 calibration mix #7B. calibration mix #7A contains Acetone (67-64-1), 2-Butanone (MEK) (78-93-3), 2-Hexanone (591-78-6), 4-Methyl-2-pentanone (MIBK) (108-10-1), Tetrahydrofuran (109-99-9); calibration mix #7B contains Acrylonitrile (107-13-1)
Allyl chloride (3-chloropropene) (107-05-1), Ethyl methacrylate (97-63-2), Methyl acrylate (96-33-3), Methyl methacrylate (80-62-6), Nitrobenzene (98-95-3), Pentachloroethane (76-01-7).
VE:
1 * 1 ST
Artikel-Nr:
(BOSSBS-7418R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7418R-A750
Lokale Artikelnummer::
BOSSBS-7418R-A750
Beschreibung:
Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. ZDHHC20 (zinc finger, DHHC-type containing 20) is a 365 amino acid multi-pass membrane protein that contains one DHHC-type zinc finger and is thought to function as a palmitoyltransferase, catalyzing the transformation of palmitoyl-CoA and a cysteine-conjugated protein to an S-palmitoyl protein and free CoA. In response to DNA damage, ZDHHC20, which exists as multiple alternatively spliced isoforms, may be phosphorylated by ATM or ATR. The gene encoding ZDHHC20 maps to human chromosome 13, which houses over 400 genes, such as BRCA2 and RB1, and comprises nearly 4% of the human genome.
VE:
1 * 100 µl
Artikel-Nr:
(PRSI91-214)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
91-214
Lokale Artikelnummer::
PRSI91-214
Beschreibung:
Inositol Monophosphatase 1 (IMPA1) belongs to the inositol monophosphatase family. IMPA1 is responsible for the provision of inositol required for synthesis of phosphatidylinositol and polyphosphoinositides, IMPA1 can use myo-inositol-1,3-diphosphate, myo-inositol-1,4-diphosphate, scyllo-inositol-phosphate, glucose-1-phosphate, glucose-6-phosphate, fructose-1-phosphate, beta-glycerophosphate, and 2-AMP as substrates. IMPA1 has been implicated as the pharmacological target for lithium action in brain. IMPA1 shows magnesium-dependent phosphatase activity and is inhibited by therapeutic concentrations of lithium. In addition, IMPA1 plays a improtant role in intracellular signal transduction.
VE:
1 * 50 µG
Artikel-Nr:
(BOSSBS-10215R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-10215R-HRP
Lokale Artikelnummer::
BOSSBS-10215R-HRP
Beschreibung:
Carbohydrate-binding lectin with a preference for chitin. Has no chitinase activity. May play a role in tissue remodeling and in the capacity of cells to respond to and cope with changes in their environment. Plays a role in T-helper cell type 2 (Th2) inflammatory response and IL-13-induced inflammation, regulating allergen sensitization, inflammatory cell apoptosis, dendritic cell accumulation and M2 macrophage differentiation. Facilitates invasion of pathogenic enteric bacteria into colonic mucosa and lymphoid organs. Mediates activation of AKT1 signaling pathway and subsequent IL8 production in colonic epithelial cells. Regulates antibacterial responses in lung by contributing to macrophage bacterial killing, controlling bacterial dissemination and augmenting host tolerance. Also regulates hyperoxia-induced injury, inflammation and epithelial apoptosis in lung.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-10215R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-10215R-A350
Lokale Artikelnummer::
BOSSBS-10215R-A350
Beschreibung:
Carbohydrate-binding lectin with a preference for chitin. Has no chitinase activity. May play a role in tissue remodeling and in the capacity of cells to respond to and cope with changes in their environment. Plays a role in T-helper cell type 2 (Th2) inflammatory response and IL-13-induced inflammation, regulating allergen sensitization, inflammatory cell apoptosis, dendritic cell accumulation and M2 macrophage differentiation. Facilitates invasion of pathogenic enteric bacteria into colonic mucosa and lymphoid organs. Mediates activation of AKT1 signaling pathway and subsequent IL8 production in colonic epithelial cells. Regulates antibacterial responses in lung by contributing to macrophage bacterial killing, controlling bacterial dissemination and augmenting host tolerance. Also regulates hyperoxia-induced injury, inflammation and epithelial apoptosis in lung.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-10215R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-10215R-A680
Lokale Artikelnummer::
BOSSBS-10215R-A680
Beschreibung:
Carbohydrate-binding lectin with a preference for chitin. Has no chitinase activity. May play a role in tissue remodeling and in the capacity of cells to respond to and cope with changes in their environment. Plays a role in T-helper cell type 2 (Th2) inflammatory response and IL-13-induced inflammation, regulating allergen sensitization, inflammatory cell apoptosis, dendritic cell accumulation and M2 macrophage differentiation. Facilitates invasion of pathogenic enteric bacteria into colonic mucosa and lymphoid organs. Mediates activation of AKT1 Signalling pathway and subsequent IL8 production in colonic epithelial cells. Regulates antibacterial responses in lung by contributing to macrophage bacterial killing, controlling bacterial dissemination and augmenting host tolerance. Also regulates hyperoxia-induced injury, inflammation and epithelial apoptosis in lung.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11574R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11574R-A680
Lokale Artikelnummer::
BOSSBS-11574R-A680
Beschreibung:
Cell cycle progression is controlled in part by a family of cyclin proteins and cyclin dependent kinases (Cdks). Cdk proteins work in concert with cyclins to phosphorylate key substrates involved in cell cycle progression. Another family of proteins, Cdk inhibitors, also play a role in regulating the cell cycle by binding to cyclin-Cdk complexes and modulating their activity. Members of the Cdk family include Cdk2Cdk8, PCTAIRE-13, PITALRE and PITSLRE. PCTAIRE-1, PCTAIRE-2 and PCTAIRE-3 comprise a subfamily of cdc2-related serine/threonine kinases. PCTAIRE-1, which is expressed primarily in mammalian brain, interacts with a variety of proteins and is thought to be part of a multiple signal transduction cascade. PCTAIRE-2, also expressed in brain, may be important in terminally differentiated neurons.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7418R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7418R-A488
Lokale Artikelnummer::
BOSSBS-7418R-A488
Beschreibung:
Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. ZDHHC20 (zinc finger, DHHC-type containing 20) is a 365 amino acid multi-pass membrane protein that contains one DHHC-type zinc finger and is thought to function as a palmitoyltransferase, catalyzing the transformation of palmitoyl-CoA and a cysteine-conjugated protein to an S-palmitoyl protein and free CoA. In response to DNA damage, ZDHHC20, which exists as multiple alternatively spliced isoforms, may be phosphorylated by ATM or ATR. The gene encoding ZDHHC20 maps to human chromosome 13, which houses over 400 genes, such as BRCA2 and RB1, and comprises nearly 4% of the human genome.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7418R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7418R-A555
Lokale Artikelnummer::
BOSSBS-7418R-A555
Beschreibung:
Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. ZDHHC20 (zinc finger, DHHC-type containing 20) is a 365 amino acid multi-pass membrane protein that contains one DHHC-type zinc finger and is thought to function as a palmitoyltransferase, catalyzing the transformation of palmitoyl-CoA and a cysteine-conjugated protein to an S-palmitoyl protein and free CoA. In response to DNA damage, ZDHHC20, which exists as multiple alternatively spliced isoforms, may be phosphorylated by ATM or ATR. The gene encoding ZDHHC20 maps to human chromosome 13, which houses over 400 genes, such as BRCA2 and RB1, and comprises nearly 4% of the human genome.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-10215R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-10215R-FITC
Lokale Artikelnummer::
BOSSBS-10215R-FITC
Beschreibung:
Carbohydrate-binding lectin with a preference for chitin. Has no chitinase activity. May play a role in tissue remodeling and in the capacity of cells to respond to and cope with changes in their environment. Plays a role in T-helper cell type 2 (Th2) inflammatory response and IL-13-induced inflammation, regulating allergen sensitization, inflammatory cell apoptosis, dendritic cell accumulation and M2 macrophage differentiation. Facilitates invasion of pathogenic enteric bacteria into colonic mucosa and lymphoid organs. Mediates activation of AKT1 signaling pathway and subsequent IL8 production in colonic epithelial cells. Regulates antibacterial responses in lung by contributing to macrophage bacterial killing, controlling bacterial dissemination and augmenting host tolerance. Also regulates hyperoxia-induced injury, inflammation and epithelial apoptosis in lung.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-10215R-PE)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-10215R-PE
Lokale Artikelnummer::
BOSSBS-10215R-PE
Beschreibung:
Carbohydrate-binding lectin with a preference for chitin. Has no chitinase activity. May play a role in tissue remodeling and in the capacity of cells to respond to and cope with changes in their environment. Plays a role in T-helper cell type 2 (Th2) inflammatory response and IL-13-induced inflammation, regulating allergen sensitization, inflammatory cell apoptosis, dendritic cell accumulation and M2 macrophage differentiation. Facilitates invasion of pathogenic enteric bacteria into colonic mucosa and lymphoid organs. Mediates activation of AKT1 signaling pathway and subsequent IL8 production in colonic epithelial cells. Regulates antibacterial responses in lung by contributing to macrophage bacterial killing, controlling bacterial dissemination and augmenting host tolerance. Also regulates hyperoxia-induced injury, inflammation and epithelial apoptosis in lung.
VE:
1 * 100 µl
Artikel-Nr:
(PRSI92-182)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
92-182
Lokale Artikelnummer::
PRSI92-182
Beschreibung:
Ankyrin repeat and SOCS box protein 13(ASB13) is a member of the ankyrin repeat and SOCS box-containing (ASB) family. ASB13 contain six ankyrin repeats sequence and a SOCS box domain. The SOCS box serves to couple suppressor of cytokine signalling (SOCS) proteins and their binding partners with the elongin B and C complex, possibly targeting them for degradation. ASB13 may be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
VE:
1 * 50 µG
Artikel-Nr:
(BOSSBS-13442R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13442R
Lokale Artikelnummer::
BOSSBS-13442R
Beschreibung:
GSTZ1 is a member of the glutathione S transferase (GSTs) super family, encoding multifunctional enzymes important in the detoxification of electrophilic molecules, including carcinogens, mutagens, and several therapeutic drugs, by conjugation with glutathione. This enzyme also plays a significant role in the catabolism of phenylalanine and tyrosine. Several transcript variants of this gene encode multiple protein isoforms. GSTZ1 shows minimal glutathione-conjugating activity with ethacrynic acid and 7-chloro-4-nitrobenz-2-oxa-1,3-diazole and maleylacetoacetate isomerase activity. It has low glutathione peroxidase activity with T butyl and cumene hydroperoxides and is able to catalyze the glutathione dependent oxygenation of dichloroacetic acid to glyoxylic acid. Highest expression in liver followed by kidney, skeletal muscle and brain. Also expressed in melanocytes, synovium, placenta, breast and fetal liver and heart.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7752R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7752R-CY5.5
Lokale Artikelnummer::
BOSSBS-7752R-CY5.5
Beschreibung:
KLHL13 (kelch like 13), also known as BKLHD2 (BTB and kelch domain containing protein 2), is a 604 amino acid protein that contains six Kelch repeats and one BTB/POZ domain. Expressed predominantly in brain, KLHL13 is believed to play a role in protein ubiquitination and may function as a substrate specific adapter of an E3 ubiquitin protein ligase complex. E3 ligases accept a ubiquitin residue from an E2 ubiquitin conjugating enzyme and immediately transfer that residue to a protein that is targeted for degradation. Specifically, KLHL13 interacts with KLHL9 and CUL3, a member of the cullin family of mediators that participate in the selective targeting of proteins for ubiquitin mediated proteolysis. Via its BTB and C terminal Kelch (BACK) motif, KLHL13 is thought to play a role in spatially orientating substrates in the CUL3 ligase.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-7752R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7752R-CY3
Lokale Artikelnummer::
BOSSBS-7752R-CY3
Beschreibung:
KLHL13 (kelch like 13), also known as BKLHD2 (BTB and kelch domain containing protein 2), is a 604 amino acid protein that contains six Kelch repeats and one BTB/POZ domain. Expressed predominantly in brain, KLHL13 is believed to play a role in protein ubiquitination and may function as a substrate specific adapter of an E3 ubiquitin protein ligase complex. E3 ligases accept a ubiquitin residue from an E2 ubiquitin conjugating enzyme and immediately transfer that residue to a protein that is targeted for degradation. Specifically, KLHL13 interacts with KLHL9 and CUL3, a member of the cullin family of mediators that participate in the selective targeting of proteins for ubiquitin mediated proteolysis. Via its BTB and C terminal Kelch (BACK) motif, KLHL13 is thought to play a role in spatially orientating substrates in the CUL3 ligase.
VE:
1 * 100 µl
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