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1,4-Benzenedimethanethiol
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1,4-Benzenedimethanethiol
Artikel-Nr:
(BOSSBS-13324R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13324R-HRP
Lokale Artikelnummer::
BOSSBS-13324R-HRP
Beschreibung:
Rab proteins, a family of Ras-related small GTP-binding proteins, play a key role in regulating intracellular vesicle trafficking (1?). Rab GDP dissociation inhibitor (Rab GDI or GDI2) forms a soluble complex with Rab proteins and thereby prevents the exchange of GDP for GTP (1?). In mammals, there exist two major isoforms, Rab GDI alpha (also known as XAP-4) and Rab GDI beta (1,4). While the mammalian Rab GDI beta-genes are ubiquitously expressed, the Rab GDI ?genes are predominantly brain-specific (1). Since it is expressed predominantly in neural and sensory tissues, Rab GDI a may serve a specific function in neural signal transmission (5). The gene sequences for the Rab GDI proteins are extremely conserved in evolution, with substantial homology preserved across three eukaryotic kingdoms (5).
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3773R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3773R-FITC
Lokale Artikelnummer::
BOSSBS-3773R-FITC
Beschreibung:
Modulation of the chromatin structure plays an important role in the regulation of transcription in eukaryotes. The nucleosome, made up of four core histone proteins (H2A, H2B, H3 and H4), is the primary building block of chromatin. The N-terminal tail of core histones undergoes different posttranslational modifications including acetylation, phosphorylation and methylation. These modifications occur in response to cell signal stimuli and have a direct effect on gene expression. In most species, the histone H2B is primarily acetylated at lysines 5, 12, 15 and 20. Histone H3 is primarily acetylated at lysines 9, 14, 18 and 23. Acetylation at lysine 9 appears to have a dominant role in histone deposition and chromatin assembly in some organisms. Phosphorylation at Ser10 of histone H3 is tightly correlated with chromosome condensation during both mitosis and meiosis.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13727R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13727R-A750
Lokale Artikelnummer::
BOSSBS-13727R-A750
Beschreibung:
Protocadherins are a large family of cadherin-like cell adhesion proteins that are involved in the establishment and maintenance of neuronal connections in the brain. There are three protocadherin gene clusters, designated alpha, beta and gamma, all of which contain multiple tandemly arranged genes. PCDHB14 (Protocadherin beta 14) is a 798 amino acid protein that is one of 16 proteins in the protocadherin beta cluster. Unlike the alpha and gamma gene clusters whos genes are spliced to downstream constant region exons during transcription, members of the beta cluster (such as PCDHB14) do not use constant-region exons to produce mRNAs. As a result, each protocadherin beta gene encodes the transmembrane, extracellular and short cytoplasmic domains of the protein. Localized to the cell membrane, PCDHB14 is a single-pass type I membrane protein that contains six cadherin domains.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12253R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12253R-HRP
Lokale Artikelnummer::
BOSSBS-12253R-HRP
Beschreibung:
Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Krüppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. ZNF219 (Zinc finger protein 219) is a 722 amino acid protein belonging to the Krüppel C2H2-type zinc-finger protein family. It is ubiquitously expressed and localizes to the nucleus. Containing 6 C2H2-type zinc fingers which function to bind DNA, ZNF219 is thought to be involved in transcriptional regulation. Specifically, ZNF219 has been identified as a transcriptional repressor that downregulates the transcription of the HMG-14 promoter.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9190R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9190R-A680
Lokale Artikelnummer::
BOSSBS-9190R-A680
Beschreibung:
Schlafen family members are preferentially expressed in lymphoid tissues and are differentially regulated during thymocyte maturation. Schlafen proteins function as suppressors of cell growth and are thought to play a role in the maintenance of T cell quiescence. The prototype member of the Schlafen family, Slfn1, is transcriptionally unregulated during thymocyte positive selection, and the induction of Slfn1 induces a G0/G1 arrest, suggesting that Slfn1 participates in the regulation of cell cycle and potentially acts as a determining factor for apoptosis. These proteins all contain a largely conserved core domain within the center of the sequence, and yet they are substantially diversified at the N terminus. Slfn14 (Schlafen family member 14) is a 912 amino acid protein belonging to the Schlafen family. Slfn14 exists as two alternatively spliced isoforms and is encoded by a gene mapping to human chromosome 17q12.
VE:
1 * 100 µl
Artikel-Nr:
(PRSI24-173)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
24-173
Lokale Artikelnummer::
PRSI24-173
Beschreibung:
Anti-INSR Recombinant Antibody [Clone: 83-14]
VE:
1 * 0,2 mg
New Product
Artikel-Nr:
(1558003.)
Lieferant:
USP
Hersteller-Artikelnummer::
1558003
Lokale Artikelnummer::
USPH1558003
Beschreibung:
USP Reference Standards are specified for use in conducting official USP–NF tests and assays. To confirm accuracy and reproducibility, USP Reference Standards are rigorously tested and evaluated by multiple independent laboratories including USP, commercial, regulatory, and academic labs. USP also provide publicly available, official documentary standards for pharmaceutical ingredients in the USP–NF that link directly with our primary reference standards.
VE:
1 * 200 mg
Artikel-Nr:
(BOSSBS-13508R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13508R-CY5
Lokale Artikelnummer::
BOSSBS-13508R-CY5
Beschreibung:
G2A (for G2 accumulation) is a seven transmembrane G protein-coupled receptor that is upregulated in response to DNA damage and stress (1). G2A is predominantly expressed in hematopoietic tissues and in hematopoietic stem cells, and it is more highly detected in pro-B cells, while lower expression is observed in immature B cells and pre-B cells (1,2). G2A is expressed throughout T cell maturation, and it is further increased in response to T-cell activation (3). Ectopic expression of a G2A fusion protein in NIH/3T3 fibroblasts induces a cell cycle arrest that is consistent with a block at the G2/M transition (1,4). G2A is also able to attenuate the proliferative effects of Bcr-Abl, a chimeric tyrosine kinase oncogene, suggesting that G2A possesses anti-oncogenic properties (5). The amino acid sequence of G2A contains a destruction box motif that is consistently observed in cyclins, where it is required for ubiquitination and proteolytic degradation (6).
VE:
1 * 100 µl
Lieferant:
Molekula
Beschreibung:
PIPES
Artikel-Nr:
(88403.080)
Lieferant:
VWR Chemicals
Lokale Artikelnummer::
VWRC88403.080
Beschreibung:
CRM - sekundäre Referenzmaterialien, vorgesehen für die Standardisierung von volumetrischen Lösungen gemäß der Pharmakopöe (Ph. Eur. und USP). Diese volumetrischen Standards werden aus hochreinen Salzen hergestellt. Der zertifizierte Massenanteil wurde durch klassische Analyse nach ISO/IEC 17025 bestimmt. Homogenitäts- und Stabilitätsstudien werden gemäß den Anforderungen von ISO 17034 und ISO Guide 35 durchgeführt. Alle volumetrischen Standards sind auf SI rückführbar (NIST NIST).
VE:
1 * 80 g
Artikel-Nr:
(EHERXA12372000ME)
Lieferant:
EHRENSTORFER
Hersteller-Artikelnummer::
XA12372000ME
Lokale Artikelnummer::
EHERXA12372000ME
Beschreibung:
Organic Standard, 1,4-Dichlorbenzol 100 µg/ml in Methanol, Packung: Glasflasche
VE:
1 * 1 mL
Artikel-Nr:
(PRSI24-200)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
24-200
Lokale Artikelnummer::
PRSI24-200
Beschreibung:
Anti-AOC3 Recombinant Antibody [Clone: TK8-14]
VE:
1 * 0,2 mg
New Product
Artikel-Nr:
(USBI031928)
Lieferant:
US Biological
Hersteller-Artikelnummer::
031928
Lokale Artikelnummer::
USBI031928
Beschreibung:
Anti-ANXA10 Rabbit Polyclonal Antibody
VE:
1 * 200 µl
Artikel-Nr:
(PRSI24-174)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
24-174
Lokale Artikelnummer::
PRSI24-174
Beschreibung:
Anti-INSR Recombinant Antibody [Clone: 83-14]
VE:
1 * 0,2 mg
New Product
Artikel-Nr:
(40039.)
Lieferant:
Biotium
Hersteller-Artikelnummer::
40039
Lokale Artikelnummer::
BTIU40039
Beschreibung:
Acridine orange (AO) stains dsDNA green (525 nm) and RNA or single stranded DNA red (650 nm). The dye is membrane-permeant and its nucleic acid binding property has been used for cell-cycle studies. Acridine orange has also been used for the detection of microorganisms in cerebrospinal fluid and other clinical specimens. We offer a highly purified form of acridine orange while most of the other commercially available grades of AO are either in zinc chloride complex form or of low purity.
VE:
1 * 10 mL
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Dieses Produkt kann nur an eine Lieferadresse versandt werden die über die entsprechende Lizenzen verfügt. Für weitere Hilfe bitte kontaktieren Sie Ihr VWR Vertriebszentrum.
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