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1,4-Diazabicyclo[2.2.2]octanebis(sulphur+dioxide)adduct
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1,4-Diazabicyclo[2.2.2]octanebis(sulphur+dioxide)adduct
Artikel-Nr:
(BOSSBS-9190R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9190R-A647
Lokale Artikelnummer::
BOSSBS-9190R-A647
Beschreibung:
Schlafen family members are preferentially expressed in lymphoid tissues and are differentially regulated during thymocyte maturation. Schlafen proteins function as suppressors of cell growth and are thought to play a role in the maintenance of T cell quiescence. The prototype member of the Schlafen family, Slfn1, is transcriptionally unregulated during thymocyte positive selection, and the induction of Slfn1 induces a G0/G1 arrest, suggesting that Slfn1 participates in the regulation of cell cycle and potentially acts as a determining factor for apoptosis. These proteins all contain a largely conserved core domain within the center of the sequence, and yet they are substantially diversified at the N terminus. Slfn14 (Schlafen family member 14) is a 912 amino acid protein belonging to the Schlafen family. Slfn14 exists as two alternatively spliced isoforms and is encoded by a gene mapping to human chromosome 17q12.
VE:
1 * 100 µl
Artikel-Nr:
(BEHRB00217652)
Lieferant:
BEHR
Hersteller-Artikelnummer::
B00217652
Lokale Artikelnummer::
BEHRB00217652
Beschreibung:
H 13-2/14, Mikroseparator, NS 14, 250×70×80 mm, Für: Clean-up station
VE:
1 * 1 ST
Artikel-Nr:
(PROOCILULM78401.2)
Lieferant:
LGC Standards PROMOCHEM
Hersteller-Artikelnummer::
CILULM78401.2
Lokale Artikelnummer::
PROOCILULM78401.2
Beschreibung:
Organic Standard, 1,4-Dioxan 1.000 µg/ml in Methanol, Packung: Glasflasche
VE:
1 * 1,2 mL
Lieferant:
Restek
Beschreibung:
Internal standard mix 8260, includes chlorobenzene-d5, 1,4-dichlorobenzene-d4, 1,4-difluorobenzene and pentafluorobenzene, 2500 μg/ml each , : N/A, Matrix: P&T Methanol
Artikel-Nr:
(PRSI2283P)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
2283P
Lokale Artikelnummer::
PRSI2283P
Beschreibung:
RIP3 peptide is used for blocking the activity of RIP3 antibody.
VE:
1 * 50 µG
Artikel-Nr:
(PRSI91-863)
Lieferant:
ProSci Inc.
Hersteller-Artikelnummer::
91-863
Lokale Artikelnummer::
PRSI91-863
Beschreibung:
Beta-1,4-galactosyltransferase 3 (B4GALT3) belongs to the glycosyltransferase 7 family. It is responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids. It is highest expression in placenta, prostate, testis, ovary, intestine and muscle, and in fetal brain.
VE:
1 * 50 µG
Artikel-Nr:
(BOSSBS-4296R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-4296R-A680
Lokale Artikelnummer::
BOSSBS-4296R-A680
Beschreibung:
One of the major pre-mRNA-binding proteins. Binds tenaciously to poly(C) sequences. Likely to play a role in the nuclear metabolism of hnRNAs, particularly for pre-mRNAs that contain cytidine-rich sequences. Can also bind poly(C) single-stranded DNA. Plays an important role in p53/TP53 response to DNA damage, acting at the level of both transcription activation and repression. When sumoylated, acts as a transcriptional coactivator of p53/TP53, playing a role in p21/CDKN1A and 14-3-3 sigma/SFN induction (By similarity). As far as transcription repression is concerned, acts by interacting with long intergenic RNA p21 (lincRNA-p21), a non-coding RNA induced by p53/TP53. This interaction is necessary for the induction of apoptosis, but not cell cycle arrest.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2423R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2423R-A350
Lokale Artikelnummer::
BOSSBS-2423R-A350
Beschreibung:
This gene encodes a transmembrane protein containing six epidermal growth factor repeats. The protein is involved in the differentiation of several cell types, including adipocytes; it is also thought to be a tumor suppressor. It is one of several imprinted genes located in a region of on chr 14q32. Certain mutations in this imprinted region can cause phenotypes similar to maternal and paternal uniparental disomy of chromosome 14 (UPD14). This gene is expressed from the paternal allele. A polymorphism within this gene has been associated with child and adolescent obesity. The mode of inheritance for this polymorphism is polar overdominance; this non-Mendelian inheritance pattern was first described in sheep with the callipyge phenotype, which is characterized by muscle hypertrophy and decreased fat mass. [provided by RefSeq, Mar 2010].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2423R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2423R-FITC
Lokale Artikelnummer::
BOSSBS-2423R-FITC
Beschreibung:
This gene encodes a transmembrane protein containing six epidermal growth factor repeats. The protein is involved in the differentiation of several cell types, including adipocytes; it is also thought to be a tumor suppressor. It is one of several imprinted genes located in a region of on chr 14q32. Certain mutations in this imprinted region can cause phenotypes similar to maternal and paternal uniparental disomy of chromosome 14 (UPD14). This gene is expressed from the paternal allele. A polymorphism within this gene has been associated with child and adolescent obesity. The mode of inheritance for this polymorphism is polar overdominance; this non-Mendelian inheritance pattern was first described in sheep with the callipyge phenotype, which is characterized by muscle hypertrophy and decreased fat mass. [provided by RefSeq, Mar 2010].
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13300R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13300R-A680
Lokale Artikelnummer::
BOSSBS-13300R-A680
Beschreibung:
GBE1 is a 702 amino acid protein that is expressed at high levels in muscle and liver and is involved in glycogen biosynthesis. Existing as a monomer, GBE1 catalyzes the transfer of alpha-1,4-linked glucosyl units from the outer end of a glycogen chain to an alpha-1,6 position on a neighboring glycogen chain and, via this catalytic activity, plays an essential role in glycogen accumulation. Defects in the gene encoding GBE1 are the cause of glycogen storage disease type 4 (GSD4) and adult polyglucosan body disease (APBD), the first of which is a metabolic disorder that is associated with the accumulation of polysaccharides and is characterized by liver disease during childhood. Unlike GSD4, APBD is a late-onset disorder that affects the central and peripheral nervous systems and is characterized by cognitive impairment, pyramidal tetraparesis and peripheral neuropathy.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-15165R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-15165R-A350
Lokale Artikelnummer::
BOSSBS-15165R-A350
Beschreibung:
C3orf14 (chromosome 3 open reading frame 14), also known as HT021, is a 128 amino acid protein that is encoded by a gene mapping to human chromosome 3p14.2. Chromosome 3 is made up of approximately 214 million bases encoding over 1,100 genes. Notably, there is a chemokine receptor gene cluster and a variety of human cancer related loci on chromosome 3. Particular regions of the chromosome 3 short arm are deleted in many types of cancer cells. Key tumor suppressing genes on chromosome 3 encode apoptosis mediator RASSF1, cell migration regulator HYAL1 and angiogenesis suppressor SEMA3B. Marfan Syndrome, porphyria, von Hippel-Lindau syndrome, osteogenesis imperfecta and Charcot-Marie-Tooth disease are a few of the numerous genetic diseases associated with chromosome 3.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3773R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3773R-CY5.5
Lokale Artikelnummer::
BOSSBS-3773R-CY5.5
Beschreibung:
Modulation of the chromatin structure plays an important role in the regulation of transcription in eukaryotes. The nucleosome, made up of four core histone proteins (H2A, H2B, H3 and H4), is the primary building block of chromatin. The N-terminal tail of core histones undergoes different posttranslational modifications including acetylation, phosphorylation and methylation. These modifications occur in response to cell signal stimuli and have a direct effect on gene expression. In most species, the histone H2B is primarily acetylated at lysines 5, 12, 15 and 20. Histone H3 is primarily acetylated at lysines 9, 14, 18 and 23. Acetylation at lysine 9 appears to have a dominant role in histone deposition and chromatin assembly in some organisms. Phosphorylation at Ser10 of histone H3 is tightly correlated with chromosome condensation during both mitosis and meiosis.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11705R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11705R-CY3
Lokale Artikelnummer::
BOSSBS-11705R-CY3
Beschreibung:
AIP1 (ASK-interacting protein 1), also known as DAB2IP (DAB2 interacting protein), is a 1,189 amino acid protein that localizes to both the membrane and the cytoplasm and contains one Ras-GAP domain, one PH domain and one C2 domain. Expressed at low levels in prostate tissue, AIP1 functions as a Ras GTPase-activating protein that interacts with ASK 1 and, via this interaction, disrupts the association of ASK 1 with an inhibitory 14-3-3 complex, thereby allowing free ASK 1 to function within the cell. AIP1 exists as multiple alternatively spliced isoforms and is down-regulated in prostate cancer tissue, suggesting a role in tumor suppression. Chromosomal aberrations in the gene encoding AIP1 are associated with acute myeloid leukemia (AML), implicating a role for AIP1 fusion proteins in tumorigenesis.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-12253R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-12253R
Lokale Artikelnummer::
BOSSBS-12253R
Beschreibung:
Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Krüppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. ZNF219 (Zinc finger protein 219) is a 722 amino acid protein belonging to the Krüppel C2H2-type zinc-finger protein family. It is ubiquitously expressed and localizes to the nucleus. Containing 6 C2H2-type zinc fingers which function to bind DNA, ZNF219 is thought to be involved in transcriptional regulation. Specifically, ZNF219 has been identified as a transcriptional repressor that downregulates the transcription of the HMG-14 promoter.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11705R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11705R-A750
Lokale Artikelnummer::
BOSSBS-11705R-A750
Beschreibung:
AIP1 (ASK-interacting protein 1), also known as DAB2IP (DAB2 interacting protein), is a 1189 amino acid protein that localizes to both the membrane and the cytoplasm and contains one Ras-GAP domain, one PH domain and one C2 domain. Expressed at low levels in prostate tissue, AIP1 functions as a Ras GTPase-activating protein that interacts with ASK 1 and, via this interaction, disrupts the association of ASK 1 with an inhibitory 14-3-3 complex, thereby allowing free ASK 1 to function within the cell. AIP1 exists as multiple alternatively spliced isoforms and is down-regulated in prostate cancer tissue, suggesting a role in tumour suppression. Chromosomal aberrations in the gene encoding AIP1 are associated with acute myeloid leukaemia (AML), implicating a role for AIP1 fusion proteins in tumourigenesis.
VE:
1 * 100 µl
Artikel-Nr:
(229-0619)
Lieferant:
Heidolph Instruments GmbH & Co.KG
Hersteller-Artikelnummer::
526-22000-00
Lokale Artikelnummer::
HEID526-22000-00
Beschreibung:
Schlauchverbinder, PTFE, für Verlängerungsschläuche Ø 0,2 - 1,4 mm
VE:
1 * 1 ST
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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