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1,4-Dibromo-3,5-difluorobenzene
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1,4-Dibromo-3,5-difluorobenzene
Artikel-Nr:
(BOSSBS-8409R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8409R-CY7
Lokale Artikelnummer::
BOSSBS-8409R-CY7
Beschreibung:
GLB1L3 is a 653 amino acid protein belonging to the glycosyl hydrolase 35 family. GLB1L3 exists as three alternatively spliced isoforms and is encoded by a gene that maps to human chromosome 11q25. With approximately 135 million base pairs and 1,400 genes, chromosome 11 makes up around 4% of human genomic DNA and is considered a gene and disease association dense chromosome. The chromosome 11 encoded Atm gene is important for regulation of cell cycle arrest and apoptosis following double strand DNA breaks. Atm mutation leads to the disorder known as ataxia-telangiectasia. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are also associated with defects in chromosome 11.
VE:
1 * 100 µl
Artikel-Nr:
(SIAL677981-1G)
Lieferant:
Sigma-Aldrich
Hersteller-Artikelnummer::
677981-1G
Lokale Artikelnummer::
SIAL677981-1G
Beschreibung:
N-tert-Butyl-3,5-dimethylanilin, Sigma-Aldrich®
VE:
1 * 1 g
Lieferant:
COMBI-BLOCKS
Beschreibung:
3,5-Dimethyl-4-hydroxyphenylboronsäurepinakolester
Artikel-Nr:
(BOSSBS-7064R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7064R-A680
Lokale Artikelnummer::
BOSSBS-7064R-A680
Beschreibung:
Associates with components of the Mediator and p160 coactivator complexes that play a role as intermediaries transducing regulatory signals from upstream transcriptional activator proteins to basal transcription machinery at the core promoter. Recruited to endogenous nuclear receptor target genes in response to the appropriate hormone. Also functions as a p53 coactivator. May thus play an important role in transcriptional regulation (By similarity). May be involved in apoptosis signaling in the presence of the reinoid CD437. Apoptosis induction involves sequestration of 14-3-3 protein(s) and mediated altered expression of multiple cell cycle regulatory genes including MYC, CCNB1 and CDKN1A. Plays a role in cell cycle progression and/or cell proliferation.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13589R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13589R-FITC
Lokale Artikelnummer::
BOSSBS-13589R-FITC
Beschreibung:
ZNF672 is a 452 amino acid nuclear protein that may be involved in transcriptional regulation. Belonging to the Krüppel C2H2-type zinc-finger protein family, ZNF672 contains 14 C2H2-type zinc fingers. ZNF672 exists as two alternatively spliced isoforms, and is encoded by a gene that maps to human chromosome 1q44. Human chromosome 1 spans 260 million base pairs, contains over 3,000 genes, comprises nearly 8% of the human genome, and houses a large number of disease-associated genes, including those that are involved in familial adenomatous polyposis, Stickler syndrome, Parkinson’s disease, Gaucher disease, schizophrenia and Usher syndrome.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-13589R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-13589R-HRP
Lokale Artikelnummer::
BOSSBS-13589R-HRP
Beschreibung:
ZNF672 is a 452 amino acid nuclear protein that may be involved in transcriptional regulation. Belonging to the Krüppel C2H2-type zinc-finger protein family, ZNF672 contains 14 C2H2-type zinc fingers. ZNF672 exists as two alternatively spliced isoforms, and is encoded by a gene that maps to human chromosome 1q44. Human chromosome 1 spans 260 million base pairs, contains over 3,000 genes, comprises nearly 8% of the human genome, and houses a large number of disease-associated genes, including those that are involved in familial adenomatous polyposis, Stickler syndrome, Parkinson’s disease, Gaucher disease, schizophrenia and Usher syndrome.
VE:
1 * 100 µl
Lieferant:
Biotium
Beschreibung:
Recognizes a protein of 36 kDa, identified as cyclin D1. Cyclin D1, one of the key cell cycle regulators, is a putative proto-oncogene overexpressed in a wide variety of human neoplasms. This antibody neutralizes the activity of cyclin D1 in vivo. About 60% of mantle cell lymphomas (MCL) contain a t(11; 14)(q13; q32) translocation resulting in over-expression of cyclin D1. This antibody is useful in identifying mantle cell lymphomas (cyclin D1 positive) from CLL/SLL and follicular lymphomas (cyclin D1 negative). Occasionally, hairy cell leukemia and plasma cell myeloma weakly express Cyclin D1.
Artikel-Nr:
(BOSSBS-7740R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-7740R-CY5.5
Lokale Artikelnummer::
BOSSBS-7740R-CY5.5
Beschreibung:
CCDC11 is a 514 amino acid protein encode by a gene that maps to human chromosome 18q21.1. Encoding over 300 genes, chromosome 18 contains about 76 million bases. Trisomy 18, or Edwards syndrome, is the second most common trisomy after Downs syndrome. Symptoms of Edwards syndrome include low birth weight, a variety of physical development defects, heart deformations and breathing difficulty. Translocation between chromosome 18 and 14 is the most common translocation in cancers, and occurs in follicular lymphomas. Niemann-Pick disease, hereditary hemorrhagic telangiectasia and erythropoietic protoporphyria are associated with chromosome 18. The TGF∫ modulators, Smad2, Smad4 and Smad7 are encoded by chromosome 18.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9675R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9675R-A555
Lokale Artikelnummer::
BOSSBS-9675R-A555
Beschreibung:
Encoding over 300 genes, chromosome 18 contains about 76 million bases. Trisomy 18, or Edwards syndrome, is the second most common trisomy after Downs syndrome. Symptoms of Edwards syndrome include low birth weight, a variety of physical development defects, heart deformations and breathing difficulty. Translocation between chromosome 18 and 14 is the most common translocation in cancers, and occurs in follicular lymphomas. Niemann-Pick disease, hereditary hemorrhagic telangiectasia and erythropoietic protoporphyria are associated with chromosome 18. The TGFβ modulators, Smad2, Smad4 and Smad7 are encoded by chromosome 18. The C18orf56 gene product has been provisionally designated C18orf56 pending further characterization.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9675R-CY7)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9675R-CY7
Lokale Artikelnummer::
BOSSBS-9675R-CY7
Beschreibung:
Encoding over 300 genes, chromosome 18 contains about 76 million bases. Trisomy 18, or Edwards syndrome, is the second most common trisomy after Downs syndrome. Symptoms of Edwards syndrome include low birth weight, a variety of physical development defects, heart deformations and breathing difficulty. Translocation between chromosome 18 and 14 is the most common translocation in cancers, and occurs in follicular lymphomas. Niemann-Pick disease, hereditary hemorrhagic telangiectasia and erythropoietic protoporphyria are associated with chromosome 18. The TGFβ modulators, Smad2, Smad4 and Smad7 are encoded by chromosome 18. The C18orf56 gene product has been provisionally designated C18orf56 pending further characterization.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9675R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9675R-CY5
Lokale Artikelnummer::
BOSSBS-9675R-CY5
Beschreibung:
Encoding over 300 genes, chromosome 18 contains about 76 million bases. Trisomy 18, or Edwards syndrome, is the second most common trisomy after Downs syndrome. Symptoms of Edwards syndrome include low birth weight, a variety of physical development defects, heart deformations and breathing difficulty. Translocation between chromosome 18 and 14 is the most common translocation in cancers, and occurs in follicular lymphomas. Niemann-Pick disease, hereditary hemorrhagic telangiectasia and erythropoietic protoporphyria are associated with chromosome 18. The TGFβ modulators, Smad2, Smad4 and Smad7 are encoded by chromosome 18. The C18orf56 gene product has been provisionally designated C18orf56 pending further characterization.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8218R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8218R-CY5.5
Lokale Artikelnummer::
BOSSBS-8218R-CY5.5
Beschreibung:
Encoding over 300 genes, chromosome 18 contains about 76 million bases. Trisomy 18, or Edwards syndrome, is the second most common trisomy after Downs syndrome. Symptoms of Edwards syndrome include low birth weight, a variety of physical development defects, heart deformations and breathing difficulty. Translocation between chromosome 18 and 14 is the most common translocation in cancers and occurs in follicular lymphomas. Niemann-Pick disease, hereditary hemorrhagic telangiectasia and erythropoietic protoporphyria are associated with chromosome 18. The TGF∫ modulators, Smad2, Smad4 and Smad7 are encoded by chromosome 18. The FAM59A gene product has been provisionally designated FAM59A pending further characterization.
VE:
1 * 100 µl
Artikel-Nr:
(ABCRAB106202.0005)
Lieferant:
ABCR
Hersteller-Artikelnummer::
AB106202.0005
Lokale Artikelnummer::
ABCRAB106202.0005
Beschreibung:
Tris(2,2,6,6-tetramethyl-3,5-heptandionato-O,O')gadolinium(III)
VE:
1 * 5 g
 This is a MarketSource item. Additional charges may apply
Lieferant:
BIONET RESEARCH
Beschreibung:
3-(3,5-Di-tert-butyl-4-hydroxyphenyl)propionsäure
Artikel-Nr:
(BOSSBS-8409R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8409R-CY5.5
Lokale Artikelnummer::
BOSSBS-8409R-CY5.5
Beschreibung:
GLB1L3 is a 653 amino acid protein belonging to the glycosyl hydrolase 35 family. GLB1L3 exists as three alternatively spliced isoforms and is encoded by a gene that maps to human chromosome 11q25. With approximately 135 million base pairs and 1,400 genes, chromosome 11 makes up around 4% of human genomic DNA and is considered a gene and disease association dense chromosome. The chromosome 11 encoded Atm gene is important for regulation of cell cycle arrest and apoptosis following double strand DNA breaks. Atm mutation leads to the disorder known as ataxia-telangiectasia. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are also associated with defects in chromosome 11.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11217R-A647)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11217R-A647
Lokale Artikelnummer::
BOSSBS-11217R-A647
Beschreibung:
Myotubularin-related protein 14 (MTMR14), also known as Jumpy, is a myotubularin-related phosphoinositol-3-phosphate (PI3P) phosphatase (1). Mutations in the MTMR14 gene have been associated with centronuclear myopathy (1). MTMR14 deficiency in mice leads to altered calcium homeostasis and muscle disorders (2). MTMR14 has also been shown to play a role in autophagy, a process that is highly regulated by phosphatidylinositides through the type III PI3K, Vps34 (3). MTMR14 was localized to autophagic isolation membranes and early autophagosomes (3). In these studies, MTMR14 inhibited autophagy and mutations of MTMR14 associated with centronuclear myopathy were also defective in autophagy inhibition. In zebrafish, MTMR14 knockdown was shown to increase the number of autophagosomes, suggesting that its activity is associated with an inhibition of autophagy (4).
VE:
1 * 100 µl
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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