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2-Amino-4,6-bis(trifluoromethyl)nicotinamide
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2-Amino-4,6-bis(trifluoromethyl)nicotinamide
Artikel-Nr:
(THOMAA23)
Lieferant:
THOMPSON & CAPPER
Hersteller-Artikelnummer::
AA23
Lokale Artikelnummer::
THOMAA23
Beschreibung:
Kaliumsulfat, Tabletten, PS KJELTABS Mineralisierungskatalysator
VE:
1 * 1.000 Tablet
Artikel-Nr:
(SIAL298301-10G)
Lieferant:
Sigma-Aldrich
Hersteller-Artikelnummer::
298301-10G
Lokale Artikelnummer::
SIAL298301-10G
Beschreibung:
Chloropentaammincobalt(III)chlorid, Sigma-Aldrich®
VE:
1 * 10 g
Lieferant:
Alfa Aesar
Beschreibung:
Kaliumchlorid 99,0-100,5% ACS
Lieferant:
Sigma-Aldrich
Beschreibung:
Phosphor(III)bromid, Sigma-Aldrich®
Artikel-Nr:
(REGE1070902)
Lieferant:
REAGECON
Hersteller-Artikelnummer::
1070902
Lokale Artikelnummer::
REGE1070902
Beschreibung:
Kaliumpermanganat 0.02 mol/l (0.1 N) in wässriger Lösung Reag. Ph. Eur. 1070902
VE:
1 * 1 L
Lieferant:
FLUOROCHEM
Beschreibung:
Ruthenium(III)chlorid Hydrat
Artikel-Nr:
(88592.LQ)
Lieferant:
Alfa Aesar
Hersteller-Artikelnummer::
88592.LQ
Lokale Artikelnummer::
ALFA88592.LQ
Beschreibung:
Kaliumbromat Konzentrat zur Verdünnung zu 0.1 N in wässriger Lösung, Acculute™ standarmäßig volumetrische Lösung
VE:
1 * 1 ST
Artikel-Nr:
(SIAL455903-25G)
Lieferant:
Sigma-Aldrich
Hersteller-Artikelnummer::
455903-25G
Lokale Artikelnummer::
SIAL455903-25G
Beschreibung:
Kaliumtetrafluoroborat, Sigma-Aldrich®
VE:
1 * 25 g
Lieferant:
CHEMPUR
Beschreibung:
Lanthan(III)nitrat Hexahydrat
Artikel-Nr:
(BOSSBS-0193R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0193R-A750
Lokale Artikelnummer::
BOSSBS-0193R-A750
Beschreibung:
Receptor tyrosine kinase involved in the development and the maturation of the central and peripheral nervous systems through regulation of proliferation, differentiation and survival of sympathetic and nervous neurons. High affinity receptor for NGF which is its primary ligand, it can also bind and be activated by NTF3/neurotrophin-3. However, NTF3 only supports axonal extension through NTRK1 but has no effect on neuron survival. Upon dimeric NGF ligand-binding, undergoes homodimerisation, autophosphorylation and activation. Recruits, phosphorylates and/or activates several downstream effectors including SHC1, FRS2, SH2B1, SH2B2 and PLCG1 that regulate distinct overlapping signaling cascades driving cell survival and differentiation. Through SHC1 and FRS2 activates a GRB2-Ras-MAPK cascade that regulates cell differentiation and survival. Through PLCG1 controls NF-Kappa-B activation and the transcription of genes involved in cell survival. Through SHC1 and SH2B1 controls a Ras-PI3 kinase-AKT1 signaling cascade that is also regulating survival. In absence of ligand and activation, may promote cell death, making the survival of neurons dependent on trophic factors. Isoform TrkA-III is resistant to NGF, constitutively activates AKT1 and NF-kappa-B and is unable to activate the Ras-MAPK signaling cascade. Antagonizes the anti-proliferative NGF-NTRK1 signaling that promotes neuronal precursors differentiation. Isoform TrkA-III promotes angiogenesis and has oncogenic activity when overexpressed.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0192R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0192R-FITC
Lokale Artikelnummer::
BOSSBS-0192R-FITC
Beschreibung:
Receptor tyrosine kinase involved in the development and the maturation of the central and peripheral nervous systems through regulation of proliferation, differentiation and survival of sympathetic and nervous neurons. High affinity receptor for NGF which is its primary ligand, it can also bind and be activated by NTF3/neurotrophin-3. However, NTF3 only supports axonal extension through NTRK1 but has no effect on neuron survival. Upon dimeric NGF ligand-binding, undergoes homodimerization, autophosphorylation and activation. Recruits, phosphorylates and/or activates several downstream effectors including SHC1, FRS2, SH2B1, SH2B2 and PLCG1 that regulate distinct overlapping signaling cascades driving cell survival and differentiation. Through SHC1 and FRS2 activates a GRB2-Ras-MAPK cascade that regulates cell differentiation and survival. Through PLCG1 controls NF-Kappa-B activation and the transcription of genes involved in cell survival. Through SHC1 and SH2B1 controls a Ras-PI3 kinase-AKT1 signaling cascade that is also regulating survival. In absence of ligand and activation, may promote cell death, making the survival of neurons dependent on trophic factors. Isoform TrkA-III is resistant to NGF, constitutively activates AKT1 and NF-kappa-B and is unable to activate the Ras-MAPK signaling cascade. Antagonizes the anti-proliferative NGF-NTRK1 signaling that promotes neuronal precursors differentiation. Isoform TrkA-III promotes angiogenesis and has oncogenic activity when overexpressed.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0193R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0193R-CY3
Lokale Artikelnummer::
BOSSBS-0193R-CY3
Beschreibung:
Receptor tyrosine kinase involved in the development and the maturation of the central and peripheral nervous systems through regulation of proliferation, differentiation and survival of sympathetic and nervous neurons. High affinity receptor for NGF which is its primary ligand, it can also bind and be activated by NTF3/neurotrophin-3. However, NTF3 only supports axonal extension through NTRK1 but has no effect on neuron survival. Upon dimeric NGF ligand-binding, undergoes homodimerization, autophosphorylation and activation. Recruits, phosphorylates and/or activates several downstream effectors including SHC1, FRS2, SH2B1, SH2B2 and PLCG1 that regulate distinct overlapping signaling cascades driving cell survival and differentiation. Through SHC1 and FRS2 activates a GRB2-Ras-MAPK cascade that regulates cell differentiation and survival. Through PLCG1 controls NF-Kappa-B activation and the transcription of genes involved in cell survival. Through SHC1 and SH2B1 controls a Ras-PI3 kinase-AKT1 signaling cascade that is also regulating survival. In absence of ligand and activation, may promote cell death, making the survival of neurons dependent on trophic factors. Isoform TrkA-III is resistant to NGF, constitutively activates AKT1 and NF-kappa-B and is unable to activate the Ras-MAPK signaling cascade. Antagonizes the anti-proliferative NGF-NTRK1 signaling that promotes neuronal precursors differentiation. Isoform TrkA-III promotes angiogenesis and has oncogenic activity when overexpressed.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-3456R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3456R-CY5.5
Lokale Artikelnummer::
BOSSBS-3456R-CY5.5
Beschreibung:
Receptor tyrosine kinase involved in the development and the maturation of the central and peripheral nervous systems through regulation of proliferation, differentiation and survival of sympathetic and nervous neurons. High affinity receptor for NGF which is its primary ligand, it can also bind and be activated by NTF3/neurotrophin-3. However, NTF3 only supports axonal extension through NTRK1 but has no effect on neuron survival. Upon dimeric NGF ligand-binding, undergoes homodimerization, autophosphorylation and activation. Recruits, phosphorylates and/or activates several downstream effectors including SHC1, FRS2, SH2B1, SH2B2 and PLCG1 that regulate distinct overlapping signaling cascades driving cell survival and differentiation. Through SHC1 and FRS2 activates a GRB2-Ras-MAPK cascade that regulates cell differentiation and survival. Through PLCG1 controls NF-Kappa-B activation and the transcription of genes involved in cell survival. Through SHC1 and SH2B1 controls a Ras-PI3 kinase-AKT1 signaling cascade that is also regulating survival. In absence of ligand and activation, may promote cell death, making the survival of neurons dependent on trophic factors. Isoform TrkA-III is resistant to NGF, constitutively activates AKT1 and NF-kappa-B and is unable to activate the Ras-MAPK signaling cascade. Antagonizes the anti-proliferative NGF-NTRK1 signaling that promotes neuronal precursors differentiation. Isoform TrkA-III promotes angiogenesis and has oncogenic activity when overexpressed.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0193R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0193R-CY5.5
Lokale Artikelnummer::
BOSSBS-0193R-CY5.5
Beschreibung:
Receptor tyrosine kinase involved in the development and the maturation of the central and peripheral nervous systems through regulation of proliferation, differentiation and survival of sympathetic and nervous neurons. High affinity receptor for NGF which is its primary ligand, it can also bind and be activated by NTF3/neurotrophin-3. However, NTF3 only supports axonal extension through NTRK1 but has no effect on neuron survival. Upon dimeric NGF ligand-binding, undergoes homodimerization, autophosphorylation and activation. Recruits, phosphorylates and/or activates several downstream effectors including SHC1, FRS2, SH2B1, SH2B2 and PLCG1 that regulate distinct overlapping signaling cascades driving cell survival and differentiation. Through SHC1 and FRS2 activates a GRB2-Ras-MAPK cascade that regulates cell differentiation and survival. Through PLCG1 controls NF-Kappa-B activation and the transcription of genes involved in cell survival. Through SHC1 and SH2B1 controls a Ras-PI3 kinase-AKT1 signaling cascade that is also regulating survival. In absence of ligand and activation, may promote cell death, making the survival of neurons dependent on trophic factors. Isoform TrkA-III is resistant to NGF, constitutively activates AKT1 and NF-kappa-B and is unable to activate the Ras-MAPK signaling cascade. Antagonizes the anti-proliferative NGF-NTRK1 signaling that promotes neuronal precursors differentiation. Isoform TrkA-III promotes angiogenesis and has oncogenic activity when overexpressed.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-0193R-A488)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-0193R-A488
Lokale Artikelnummer::
BOSSBS-0193R-A488
Beschreibung:
Receptor tyrosine kinase involved in the development and the maturation of the central and peripheral nervous systems through regulation of proliferation, differentiation and survival of sympathetic and nervous neurons. High affinity receptor for NGF which is its primary ligand, it can also bind and be activated by NTF3/neurotrophin-3. However, NTF3 only supports axonal extension through NTRK1 but has no effect on neuron survival. Upon dimeric NGF ligand-binding, undergoes homodimerization, autophosphorylation and activation. Recruits, phosphorylates and/or activates several downstream effectors including SHC1, FRS2, SH2B1, SH2B2 and PLCG1 that regulate distinct overlapping signaling cascades driving cell survival and differentiation. Through SHC1 and FRS2 activates a GRB2-Ras-MAPK cascade that regulates cell differentiation and survival. Through PLCG1 controls NF-Kappa-B activation and the transcription of genes involved in cell survival. Through SHC1 and SH2B1 controls a Ras-PI3 kinase-AKT1 signaling cascade that is also regulating survival. In absence of ligand and activation, may promote cell death, making the survival of neurons dependent on trophic factors. Isoform TrkA-III is resistant to NGF, constitutively activates AKT1 and NF-kappa-B and is unable to activate the Ras-MAPK signaling cascade. Antagonizes the anti-proliferative NGF-NTRK1 signaling that promotes neuronal precursors differentiation. Isoform TrkA-III promotes angiogenesis and has oncogenic activity when overexpressed.
VE:
1 * 100 µl
Artikel-Nr:
(SCOI285138608)
Lieferant:
SI Analytics
Hersteller-Artikelnummer::
285138608
Lokale Artikelnummer::
SCOI285138608
Beschreibung:
Kaliumchlorid 4.2 mol/l (4.2 N) in wässriger Lösung
VE:
1 * 250 mL
Preis auf Anfrage
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 noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das
noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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