cis-1,2,3,6-Tetrahydrophthalimide
Artikel-Nr:
(BOSSBS-6577R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-6577R-CY5.5
Lokale Artikelnummer::
BOSSBS-6577R-CY5.5
Beschreibung:
S100PBP was originally cloned from a pancreatic epithelioid carcinoma library and encodes a predicted 408 amino acid protein. RT-PCR detected S100PBP expression in brain, breast, spleen, and lung, but not in pancreas and liver. GFP-tagged S100PBP localized to nuclei of transfected HeLa cells.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8317R)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8317R
Lokale Artikelnummer::
BOSSBS-8317R
Beschreibung:
HDHD2 (haloacid dehalogenase-like hydrolase domain containing 2) is also known as DKFZp564D1378 and is a 259 amino acid protein that is expressed as two isoforms produced by alternative splicing. HDHD2 belongs to the HAD-like hydrolase superfamily, which contains a group of hydrolase enzymes that differ from the å/∫
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8317R-CY5.5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8317R-CY5.5
Lokale Artikelnummer::
BOSSBS-8317R-CY5.5
Beschreibung:
HDHD2 (haloacid dehalogenase-like hydrolase domain containing 2) is also known as DKFZp564D1378 and is a 259 amino acid protein that is expressed as two isoforms produced by alternative splicing. HDHD2 belongs to the HAD-like hydrolase superfamily, which contains a group of hydrolase enzymes that differ from the å/∫
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-2060R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-2060R-CY5
Lokale Artikelnummer::
BOSSBS-2060R-CY5
Beschreibung:
Forms a channel with a broad specificity. Mediates passage of a wide variety of non-charged solutes including carbamides, polyols, purines, and pyrimidines in a phloretin- and mercury-sensitive manner, whereas amino acids, cyclic sugars, Na(+), K(+), Cl(-), and deprotonated monocarboxylates are excluded. Also permeable to urea and glycerol.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8317R-CY5)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8317R-CY5
Lokale Artikelnummer::
BOSSBS-8317R-CY5
Beschreibung:
HDHD2 (haloacid dehalogenase-like hydrolase domain containing 2) is also known as DKFZp564D1378 and is a 259 amino acid protein that is expressed as two isoforms produced by alternative splicing. HDHD2 belongs to the HAD-like hydrolase superfamily, which contains a group of hydrolase enzymes that differ from the å/∫
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8155R-A350)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8155R-A350
Lokale Artikelnummer::
BOSSBS-8155R-A350
Beschreibung:
Golgi auto-antigen; probably involved in maintaining cis-Golgi structure.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8155R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8155R-FITC
Lokale Artikelnummer::
BOSSBS-8155R-FITC
Beschreibung:
Golgi auto-antigen; probably involved in maintaining cis-Golgi structure.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-8155R-A680)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-8155R-A680
Lokale Artikelnummer::
BOSSBS-8155R-A680
Beschreibung:
Golgi auto-antigen; probably involved in maintaining cis-Golgi structure.
VE:
1 * 100 µl
Artikel-Nr:
(BNUM0890-50)
Lieferant:
Biotium
Hersteller-Artikelnummer::
BNUM0890-50
Lokale Artikelnummer::
BTIUBNUM0890-50
Beschreibung:
This antibody recognizes a glycoprotein of 75 kDa, identified as low affinity Nerve Growth Factor (NGF) Receptor (p75NGFR) or Neurotrophin Receptor (p75NTR). Its epitope spans in aa 1-160 of extracellular domain of NGFR/NTR. NGF-receptor contains an extracellular domain containing four 40-amino acid repeats with 6 cysteine residues at conserved positions followed by a serine/threonine-rich region, a single transmembrane domain, and a 155-amino acid cytoplasmic domain. The cysteine-rich region contains the nerve growth factor binding domain. NGF is important for the development, differentiation, and survival of variety of neuronal and non-neuronal cells. Its action is mediated by binding two distinct receptors, the high affinity p140 and low affinity p75.
VE:
1 * 50 µl
Artikel-Nr:
(BLDPBD150735-25G)
Lieferant:
BLD PHARMATECH GMBH
Hersteller-Artikelnummer::
BD150735-25G
Lokale Artikelnummer::
BLDPBD150735-25G
Beschreibung:
Safranin O BS
VE:
1 * 25 g
Artikel-Nr:
(BOSSBS-3919R-FITC)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-3919R-FITC
Lokale Artikelnummer::
BOSSBS-3919R-FITC
Beschreibung:
STARD5, or START domain containing 5, belongs to a family containing a 200- to 210-amino acid STAR-related lipid transfer (START) domain. STARD5 may be involved in the intracellular transport of sterols or other lipids and may bind cholesterol or other sterols.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1302R-CY3)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1302R-CY3
Lokale Artikelnummer::
BOSSBS-1302R-CY3
Beschreibung:
Glutamic Acid Decarboxylase (GAD) catalyzes the conversion of L glutamate to g-aminobutyric acid (GABA), the principal inhibitory neurotransmitter in the brain, and a putative paracrine signal molecule in pancreatic islets. GAD has a restricted tissue distribution. It is highly expressed in the cytoplasm of GABAergic neurons in the central nervous system (CNS) and pancreatic beta cells. It is also present in other non-neuronal tissues such as testis, oviduct and ovary. GAD is also transiently expressed in non-GABAergic cells of the embryonic and adult nervous system, suggesting its involvement in development and plasticity. GAD exists as two isoforms, GAD65 and GAD67 (molecular masses of 65 and 67 kD, respectively) that are encoded by two different genes. GAD65 is an ampiphilic, membraneanchored protein, (585 amino acid residues) and is encoded on human chromosome 10. GAD67 is a cytoplasmic protein (594 amino acid residues) and is encoded on chromosome 2. There is 64% amino acid identity between the two isoforms, with the highest diversity located at the N terminus, which in GAD65 is required for targeting the enzyme to GABA-containing secretory vesicles. The two isoforms appear to have distinct intraneuronal distribution in the brain. GAD65 has been identified as an autoantigen in insulindependent diabetes mellitus (IDDM) and stiff-man syndrome (SMS), IDDM is an autoimmune disease that results from T cell mediated destruction of pancreatic insulin-secreting beta cells. Islet-reactive T cells and primarily to GAD65 (also named beta cell autoantigen) can be detected in peripheral blood of 80% of recent-onset IDD patients and in pre-diabetic high-risk subjects before onset of clinical symptoms. This suggests that GAD may be an important marker in the early stages of the disease.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-1302R-A750)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-1302R-A750
Lokale Artikelnummer::
BOSSBS-1302R-A750
Beschreibung:
Glutamic Acid Decarboxylase (GAD) catalyses the conversion of L glutamate to g-aminobutyric acid (GABA), the principal inhibitory neurotransmitter in the brain, and a putative paracrine signal molecule in pancreatic islets. GAD has a restricted tissue distribution. It is highly expressed in the cytoplasm of GABAergic neurons in the central nervous system (CNS) and pancreatic beta cells. It is also present in other non-neuronal tissues such as testis, oviduct and ovary. GAD is also transiently expressed in non-GABAergic cells of the embryonic and adult nervous system, suggesting its involvement in development and plasticity. GAD exists as two isoforms, GAD65 and GAD67 (molecular masses of 65 and 67 kD, respectively) that are encoded by two different genes. GAD65 is an ampiphilic, membraneanchored protein, (585 amino acid residues) and is encoded on human chromosome 10. GAD67 is a cytoplasmic protein (594 amino acid residues) and is encoded on chromosome 2. There is 64% amino acid identity between the two isoforms, with the highest diversity located at the N terminus, which in GAD65 is required for targeting the enzyme to GABA-containing secretory vesicles. The two isoforms appear to have distinct intraneuronal distribution in the brain. GAD65 has been identified as an autoantigen in insulindependent diabetes mellitus (IDDM) and stiff-man syndrome (SMS), IDDM is an autoimmune disease that results from T cell mediated destruction of pancreatic insulin-secreting beta cells. Islet-reactive T cells and primarily to GAD65 (also named beta cell autoantigen) can be detected in peripheral blood of 80% of recent-onset IDD patients and in pre-diabetic high-risk subjects before onset of clinical symptoms. This suggests that GAD may be an important marker in the early stages of the disease.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-11491R-HRP)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-11491R-HRP
Lokale Artikelnummer::
BOSSBS-11491R-HRP
Beschreibung:
TorsinB is a 336 amino acid protein that localizes to the lumen of endoplasmic reticulum and belongs to the Torsin family. Expressed in a variety of tissues with particularly high levels in adult brain, TorsinB is thought to function as a molecular chaperone that assists in the conformational folding of membrane and secreted proteins. Via its ability to regulate protein folding, TorsinB plays a key role in postnatal developmental events and is essential for proper neurological development. TorsinB contains two PKC (protein kinase C) phosphorylations sites, one ATP binding domain and several conserved cysteines and shares 69% amino acid identity with TorsinA, a related family member. Defects in the gene encoding TorsinB are associated with torsion dystonia, an autosomal dominant neurological disorder that is characterized by debilitating muscle contractions throughout the body.
VE:
1 * 100 µl
Artikel-Nr:
(BOSSBS-9554R-A555)
Lieferant:
Bioss
Hersteller-Artikelnummer::
BS-9554R-A555
Lokale Artikelnummer::
BOSSBS-9554R-A555
Beschreibung:
GTP-binding protein 9 is a 396 amino acid protein that belongs to the Obg-related GTPase family under the translation factors (TRAFAC) class. Originally thought to only have GTPase activity, Obg-related GTPase family members have been shown to also have ATPase activity. In Homo sapians, GTPBP9 exhibits a preference for binding ATP over GTP, with GTP binding occuring only at high nucleotide concentration. One cause for ATP affinity and GTP discrimination is thought to be a substitution of glutamine for a hydrophobic amino acid in Obg-related family members; this is the same substitution that inactivates Ras-like GTPases. GTPBP9 contains a C-terminal TGS domain that binds to ligands and an N-terminal G domain which binds nucleotides. GTPBP9 is expressed as three isoforms produced by alternative splicing.
VE:
1 * 100 µl
Lieferant:
Biotium
Beschreibung:
Myogenin is a member of the MyoD family of myogenic basic helix-loop-helix (bHLH) transcription factors that also includes MyoD, Myf-5, and MRF4 (also known as herculinor Myf-6). MyoD family members are expressed exclusively in skeletal muscle and play a key role in activating myogenesis by binding to enhancer sequences of muscle-specific genes. The regulatory domain of MyoD is approximately 70 amino acids in length and includes both a basic DNA binding motif and a bHLH dimerization motif. MyoD family members share about 80% amino acid homology in their bHLH motifs. Anti-myogenin labels the nuclei of myoblasts in developing muscle tissue, and is expressed in tumor cell nuclei of rhabdomyosarcoma and some leiomyosarcomas. Positive nuclear staining may occur in Wilms' tumor.
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